Abstracts tagged "axial spondyloarthritis"

Abstract Number: 2569 • 2018 ACR/ARHP Annual Meeting
Association of Enthesitis with Achievement of Normal Quality of Life and Clinical Response in Patients with Non-Radiographic Axial Spondyloarthritis Treated with Adalimumab
Philip J. Mease¹, Filip van Den Bosch², Uta Kiltz³, Patrick Zueger⁴, Kun Chen⁴, Meijing Wu⁴ and Jaclyn K. Anderson⁴, ¹Swedish Medical Center and University of Washington, Seattle, WA, ²Ghent University, Ghent, Belgium, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴AbbVie Inc., North Chicago, IL
Background/Purpose: Enthesitis, a key pathology in non-radiographic axial spondyloarthritis (nr-axSpA), has been difficult to treat with conventional therapies and may take longer to resolve than…
Abstract Number: 1620 • 2018 ACR/ARHP Annual Meeting
Lateral DXA More Effective in Detecting Osteoporosis Than Conventional DXA in Axial Spondyloarthropathy
Gillian Fitzgerald^1,2, Jason Wyse³, Tochukwu Anachebe⁴, Ronan Mullan⁵, David Kane⁶, Kevin McCarroll⁷ and Finbar O' Shea², ¹School of Medicine, Trinity College Dublin, Dublin 2, Ireland, ²Rheumatology, St. James's Hospital, Dublin 8, Ireland, ³School of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland, ⁴Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, ⁵Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, ⁶Department of Rheumatology, Tallaght Hospital, TCD, Dublin 24, Ireland, ⁷Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland
Background/Purpose: The severe consequences of osteoporosis in the general population are well outlined. In axial spondyloarthropathy (axSpA), osteoproliferation of the spine means posterioanterior (PA) dual-energy…
Abstract Number: 2581 • 2018 ACR/ARHP Annual Meeting
Comparing Treatment Patterns of Non-Radiographic Axial Spondyloarthritis Patients in the United States and Europe
Theresa Hunter¹, David Sandoval Calderon¹, Steve Lobosco², Rachel Moon², Gary Milligan³ and Rebecca Bolce¹, ¹Eli Lilly and Company, Indianapolis, IN, ²Adelphi Real World, Macclesfield, United Kingdom, ³Adelphi Real World, Macclesfield,, United Kingdom
Background/Purpose: To compare TNF inhibitor (TNFi) use and switching patterns among patients with nr-axSpA in the United States (US) and Europe (EU). Methods: Data from…
Abstract Number: 330 • 2018 ACR/ARHP Annual Meeting
The IMPACT of a Referral Algorithm for Axial Spondyloarthritis: Four Month Follow-up in Patient Reported Outcomes
Maha Jamal¹, Amber Korver², Martijn Kuijper³, Deirisa Lopes Barreto¹, Frank van den Hoogen⁴, Cathelijne W. Y. Appels⁵, Anneke Spoorenberg⁶, Bart Koes⁷, Lonneke van Hoeven⁸, JMW Hazes⁹ and Angelique EAM Weel³, ¹Maasstad Hospital, Rotterdam, Netherlands, ²Erasmuc Medical Center, Rotterdam, Netherlands, ³Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁴Radboud Medical center, Nijmegen, Netherlands, ⁵Rheumatology, Amphia Hospital, Breda, Netherlands, ⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁷Erasmuc Medical center, Rotterdam, Netherlands, ⁸Erasmus Medical center, Rotterdam, Netherlands, ⁹Rheumatology, Erasmus MC, Rotterdam, Netherlands
Background/Purpose: A substantial amount of patients with chronic low back pain (CLBP) have axial spondyloarthritis (axSpA), but early recognition of these patients is difficult for…
Abstract Number: 1621 • 2018 ACR/ARHP Annual Meeting
Higher Serum Uric Acid Levels Protect Against Osteoporosis in Patients with Axial Spondyloarthropathy
Gillian Fitzgerald^1,2, Tochukwu Anachebe³, Ronan Mullan⁴, David Kane⁵, Kevin McCarroll⁶ and Finbar O' Shea², ¹School of Medicine, Trinity College Dublin, Dublin 2, Ireland, ²Rheumatology, St. James's Hospital, Dublin 8, Ireland, ³Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, ⁴Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, ⁵Department of Rheumatology, Tallaght Hospital, Dublin 24, Ireland, ⁶Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland
Background/Purpose: High serum urate (SUA) is a risk factor for metabolic disease, including hypertension and coronary artery disease. However, SUA has an antioxidant effect and…
Abstract Number: 2601 • 2018 ACR/ARHP Annual Meeting
Nonsteroidal Anti-Inflammatory Drugs Attenuate Active Inflammatory Sacroiliac Joint Lesions in Patients with Early Axial Spondyloarthritis
Hong-Ki Min¹, Hyonjoung Cho² and Sung-Hwan Park³, ¹Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Armed Forces Capital hospital, Armed Forces Medical Command, Seongnam, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
Background/Purpose: The purpose of the present study was to examine the therapeutic effect of NSAIDs on active inflammatory lesions (bone marrow oedema [BMO]) in the…
Abstract Number: 642 • 2018 ACR/ARHP Annual Meeting
Cost of Illness Analysis before and after Initiation of Tumour Necrosis Factor α Inhibitors in Patients with Axial Spondyloarthritis
Imke Redeker¹, Falk Hoffmann², Johanna Callhoff¹, Hildrun Haibel³, Joachim Sieper⁴, Angela Zink⁵ and Denis Poddubnyy⁴, ¹Epidemiology Unit, German Rheumatism Research Centre, Berlin, Germany, ²Department of Health Services Research, Carl von Ossietzky University, Oldenburg, Germany, ³Charité Universitätmedizin Berlin, Berlin, Germany, ⁴Rheumatology, Charité Universitätsmeidzin Berlin, Berlin, Germany, ⁵Epidemiology Unit / Rheumatology and Clinical Immunology, German Rheumatism Research Centre (DRFZ) / Charité University Hospital, Berlin, Germany
Background/Purpose: Tumour necrosis factor-α inhibitors (TNFi) are an effective but rather expensive treatment option in axial spondyloarthritis (axSpA) patients who fail conventional treatment. The aim…
Abstract Number: 1626 • 2018 ACR/ARHP Annual Meeting
The Disease Expression in Familial and Sporadic Axial Spondyloarthritis Patients
Dilek Solmaz¹, Onay Gercik², Gökhan Kabadayı¹ and Servet Akar³, ¹Rheumatology, Izmir Katip Celebi University, Faculty of Medicine, Izmir, Turkey, ²Rheumatology, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, ³Faculty of Medicine, Department of Rheumatology, Izmir Katip Celebi University, Izmir, Turkey
Background/Purpose: Familial aggregation of the SpA in particular AS has long been known and up to 40% of AS patients have a positive family history…
Abstract Number: 2862 • 2018 ACR/ARHP Annual Meeting
Magnitude of Response to TNF Inhibitors in Children with Spondyloarthritis and Sacroiliitis
Rosemary Peterson¹, Rui Xiao², Timothy G. Brandon³, David M. Biko⁴, Michael Francavilla⁴, Nancy A. Chauvin⁵ and Pamela F. Weiss⁶, ¹Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Radiology, Penn State Hershey Medical Center, Hershey, PA, ⁶Pediatrics, Children's Hospital Philadelphia, Philadelphia, PA
Background/Purpose: We aimed to quantify the magnitude of biologic effect on sacroiliitis in juvenile SpA by comparing the change in the Spondyloarthritis Research Consortium of…
Abstract Number: 646 • 2018 ACR/ARHP Annual Meeting
Do Ethnicity, Degree of Family Relationship, and the Spondyloarthritis Subtype in Affected Relatives Influence the Association between a Positive Family History for Spondyloarthritis and HLA-B27 Carriership? Results from the Worldwide ASAS Cohort
Miranda van Lunteren¹, Alexandre Sepriano^1,2, Robert B.M. Landewé^3,4, Joachim Sieper^5,6, Martin Rudwaleit^6,7, Désirée van der Heijde¹ and Floris van Gaalen¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal, ³Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, ⁴Rheumatology, Zuyderland Hospital, Heerlen, Netherlands, ⁵German Rheumatism Research Centre, Berlin, Germany, ⁶Rheumatology, Charité Campus Benjamin Franklin, Berlin, Germany, ⁷Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) defines a positive family history (PFH) of spondyloarthritis (SpA) as presence of ankylosing spondylitis (AS), acute anterior…
Abstract Number: 1645 • 2018 ACR/ARHP Annual Meeting
Clinical Features of Axial Spondyloarthritis Patients Diagnosed in Secondary Versus a Tertiary Hospital
Ann-Sophie De Craemer^1,2, Thomas Renson^1,2, Philippe Carron^1,2, Peggy Jacques^1,2, Rik Joos^1,3,4, Jan Lenaerts^5,6, Lieve Gyselbrecht⁷, Filip van Den Bosch^1,2 and Dirk Elewaut^1,2, ¹Department of Rheumatology, Ghent University Hospital, Ghent, 9000, Belgium, ²VIB Inflammation Research Center, Ghent, 9000, Belgium, ³Department of Rheumatology, Antwerp University Hospital, Edegem, 2650, Belgium, ⁴Department of Rheumatology, ZNA Jan Palfijn, Merksen, 2170, Belgium, ⁵Reuma Institute Hasselt, Hasselt, 3500, Belgium, ⁶Department of Rheumatology, Leuven University Hospital, Leuven, 3000, Belgium, ⁷Department of Rheumatology, ASZ Aalst, Aalst, 9300, Belgium
Background/Purpose: Diagnosis of axial spondyloarthritis (axSpA) often relies on a positive MRI of the SI joints. However, pitfalls in interpretation of MRI images were recently…
Abstract Number: 2891 • 2018 ACR/ARHP Annual Meeting
Eligibility Criteria for TNFi Therapy in Axial Spa: Going Beyond Basdai
José Marona^1,2, Alexandre Sepriano^2,3, Santiago Rodrigues Manica^1,2, Fernando Pimentel-Santos^1,2, Ana Filipa Mourão^1,2, Nélia Gouveia², Jaime Cunha Branco^1,2, Filipe Vinagre⁴, Raquel Roque⁴, João Rovisco⁵, Mary Lucy Marques⁵, José Tavares Costa⁶, Joana Leite Silva⁶, Helena Santos⁷, Nathalie Madeira⁷, Elsa Vieira-Sousa^8,9, Ana Rita Machado¹⁰, Miguel Bernardes¹¹, Raquel Ferreira¹¹ and Sofia Ramiro^2,12,13, ¹Rheumatology, Hospital de Egas Moniz - Centro Hospitalar Lisboa Ocidental, EPE, Lisbon, Portugal, ²CEDOC, NOVA Medical School, Lisbon, Portugal, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Hospital Garcia de Orta, Almada, Portugal, ⁵Rheumatology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ⁶Rheumatology, Unidade Local de Saúde do Alto Minho, Ponte de Lima, Portugal, ⁷Rheumatology, Instituto Português de Reumatologia, Lisbon, Portugal, ⁸Rheumatology and Metabolic Bone Diseases, Hospital de Santa Maria - Centro Hospitalar Lisboa Norte, EPE, Lisbon, Portugal, ⁹Rheumatology Research Unit, Instituto de Medicina Molecular - Faculty of Medicine, University of Lisbon, Lisbon Academic Medical Centre, Lisbon, Portugal, ¹⁰Serviço de Reumatologia e Doenças Ósseas Metabólicas, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisboa, Portugal, Lisboa, Portugal, ¹¹Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, ¹²Department of Rheumatology, Leiden University Medical Centre, Leiden, Netherlands, ¹³Department of Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands
Background/Purpose: A BASDAI ≥4 has often been required to start TNF inhibitors (TNFi) therapy in patients with axial SpA (axSpA). However, this cut-off of high…
Abstract Number: 651 • 2018 ACR/ARHP Annual Meeting
Analysis of the Different Value of Magnetic Resonance Imaging Changes in the Sacroiliac Joints for a Diagnosis of Axial Spondyloarthritis As Judged By Rheumatologists and Radiologists
Xenofon Baraliakos¹, Ana Ghadir², Martin Fruth², Uta Kiltz³ and Jürgen Braun¹, ¹Ruhr-University Bochum, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Rheumatology, Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany
Background/Purpose: Classification of axial spondyloarthritis (axSpA) by the imaging arm of the ASAS criteria relies partly on the detection of a bone marrow edema (BME)…
Abstract Number: 1652 • 2018 ACR/ARHP Annual Meeting
Musculoskeletal Involvement in Inflammatory Bowel Disease’S Patients: A Mono Centric Experience
Andrea Delle Sedie¹, Linda Ceccarelli², Linda Carli¹, Francesco Costa³, Santino Marchi³ and Marta Mosca¹, ¹Rheumatology Unit, University of Pisa, Pisa, Italy, ²University Gastroenterology Unit, University of Pisa, Pisa, Italy, ³University Gastroenterology Unit, University of Pisa,, Pisa, Italy
Background/Purpose: Musculoskeletal symptoms are frequently reported by patients with inflammatory bowel diseases (IBD). Those symptoms may vary from arthralgia to arthritis, involving peripheral or axial…
Abstract Number: 2944 • 2018 ACR/ARHP Annual Meeting
Longitudinal Outcomes and Predictors of E-Learning Effectiveness in Patients with Axial Spondyloarthritis: A Randomized Controlled Trial
Daeria O. Lawson¹, Ahmed Omar^1,2, Rita Kang³, Nigil Haroon^1,2, Robert D Inman^1,4 and Laura Passalent^1,5, ¹Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, ³Patient and Family Education, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, ⁵Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada
Background/Purpose: There is evidence that education programs are effective (e.g. improved disease activity and quality of life) for patients with arthritis, but little is known…

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