Abstracts tagged "axial spondyloarthritis"

Abstract Number: 2776 • 2019 ACR/ARP Annual Meeting
5-years Treatment Effect of TNF Alpha Inhibitor in Early Axial Spondyloarthritis and Associated Factors: An Inverse Probability Weighting Analysis of the DESIR Cohort
Marion Pons ¹, Sylvie Chevret ², Karine Briot ¹, Maria-Antonietta D’Agostino ³, Christian Roux ⁴, Maxime Dougados ⁵ and Anna Moltó⁴, ¹Rheumatology department, Cochin Hospital, Paris, Paris, Ile-de-France, France, ²INSERM U-1153, CRESS Paris-Sorbonne, Paris, Paris, Ile-de-France, France, ³Department of Rheumatology, APHP, Hôpital Ambroise Paré, Paris, France, ⁴Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁵Cochin Hospital, Paris, France
Background/Purpose: Only scarce date is available on the long term treatment effect in a real-life setting (i.e. effectiveness) of TNFi in early axial SpA forms…
Abstract Number: 563 • 2019 ACR/ARP Annual Meeting
The Impact of Sex and Disease Classification on Patient-reported Outcome Measures in Axial Spondyloarthritis: A Descriptive Prospective Cross-sectional Study
Rikke Andreasen¹, Lars Erik Kristensen ², Kenneth Egstrup ¹, Xenofon Baraliakos ³, Vibeke Strand ⁴, Hans Christian Horn ⁵, Inger Marie Hansen ¹, Robin Christensen ⁶ and Torkell Ellingsen ⁷, ¹Odense University Hospital, Svendborg, Svendborg, Denmark, ²Musculoskeletal Statistics Unit, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany, Herne, Germany, ⁴Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ⁵Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark, Odense, Denmark, ⁶Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital & Department of Rheumatology, Institute of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark, ⁷Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark
Background/Purpose: To explore the impact of sex and disease classification on outcomes in axial spondyloarthritis (axSpA) patients, including both ankylosing spondylitis (AS) and non-radiographic (nr-)…
Abstract Number: 603 • 2019 ACR/ARP Annual Meeting
Are the Modified New York and ASAS Criteria Interchangeable in the Classification of Patients with Spondyloarthritis with Radiographic Sacroiliitis?
Anne Boel¹, Anna Moltó ², Désirée van der Heijde ³, Adrian Ciurea ⁴, Maxime Dougados ⁵, Lianne Gensler ⁶, Maria José Santos ⁷, Eugenio de Miguel ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Astrid van Tubergen ¹¹, Floris van Gaalen ³ and Sofia Ramiro ¹², ¹Leiden University Medical Centre, Leiden, Netherlands, ²Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Hospital Zürich, Zürich, Switzerland, ⁵Cochin Hospital, Paris, France, ⁶University San Francisco California, San Francisco, CA, ⁷Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ⁸Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Maastricht University Medical Centre and Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands, ¹²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands
Background/Purpose: Patients with axial spondyloarthritis (axSpA) with radiographic sacroiliitis may be classified using the modified New York (mNY) criteria as ankylosing spondylitis and using the…
Abstract Number: 748 • 2019 ACR/ARP Annual Meeting
Takayasu Arteritis and Sacroiliitis: A Case Control Study in 28 Patients of a Single Italian Center
Paola Toniati¹, Francesca Regola ¹, Franco Franceschini ¹, Giovanni Bosio ² and Angela Tincani ³, ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, Brescia, Italy, ²Nuclear Medicine Unit, ASST Spedali Civili of Brescia, Brescia, Italy, Brescia, Italy, ³Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, Brescia, Italy
Background/Purpose: A lot of clinical case descriptions about spondyloarthropathy in TAK patients were reported. Recently, a paper about an increased incidence of spondyloarthropathy in TAK…
Abstract Number: 1487 • 2019 ACR/ARP Annual Meeting
Impact of TNF-α Inhibitor on Lipid Profile and Atherogenic Index of Plasma in Axial Spondyloarthritis: Two-year Follow-up Data from the Catholic Axial Spondyloarthritis COhort (CASCO)
Hong Ki Min¹, Seung-Ki Kwok ² and Sang-Heon Lee ¹, ¹Konkuk university medical center, Seoul, Republic of Korea, ²Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Background/Purpose: To evaluate the influence of TNF-α inhibitor on lipid profile and atherogenic index of plasma (AIP) in axial spondyloarthritis (axSpA) patients with long term…
Abstract Number: 1548 • 2019 ACR/ARP Annual Meeting
Drug Survival of Secukinumab for Axial Spondyloarthritis in a Real-World Setting Possible Response Factors
Carolina Merino Argumanez¹, Valentina Emperiale ², María Martín ³, Marta Valero ⁴, javier Bachiller ⁵, Beatriz Joven-Ibáñez ⁶, Ana Pérez-Gómez ⁷ and Jose Campos ¹, ¹Hospital Universitario Puerta de Hierro, Majadahonda (Madrid), Spain, ²Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain, ³Hospital Universitario Doce de Octubre, Madrid, Spain, ⁴Hospital Universitario Ramón y Cajal, Madrid, Spain, ⁵Rheumatology Department, Ramón y Cajal University Hospital & IRYCIS, Madrid, Spain, ⁶Hospital Universitario 12 de Octubre, Madrid, Spain, ⁷Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
Background/Purpose: Secukinumab is a newly introduced biologic therapy against IL-17 which has been proved effective in patients with ankylosing spondylitis (AS) in clinical trials and…
Abstract Number: 2777 • 2019 ACR/ARP Annual Meeting
What Is Axial Spondyloarthritis? A Latent Class and Transition Analysis in the SPACE and DESIR Cohorts
Alexandre Sepriano¹, Sofia Ramiro ², Désirée van der Heijde ¹, Pierre Hoonhout ³, Anna Moltó ⁴, Alain Saraux ⁵, Maxime Dougados ⁶ and Robert B.M. Landewé ⁷, ¹Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, ³ISEG - Lisbon School of Economics and Management, Lisbon, Portugal, ⁴Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁵CHU de la Cavale-Blanche Brest, Brest, France, ⁶Cochin Hospital, Paris, France, ⁷Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: Axial spondyloarthritis (axSpA) is a disease with a rather heterogeneous presentation that may be difficult to diagnose. Classification criteria, such as the ASAS criteria,…
Abstract Number: 567 • 2019 ACR/ARP Annual Meeting
Worse Outcomes for Female Patients with Axial Spondyloarthropathy
Sinead Maguire¹, Gillian Fitzgerald ², Claire Sheehy ³ and Finbar O'Shea ², ¹University Hospital Waterford, Dublin, Ireland, ²St James' Hospital, Dublin, Ireland, ³University Hospital Waterford, Waterford, Ireland
Background/Purpose: Axial Spondyloarthritis(axSpA) is known to have a male predominance. There is little available literature examining affected female patients. Previous studies have included small numbers…
Abstract Number: 604 • 2019 ACR/ARP Annual Meeting
Do Illness Perceptions and Coping Change over Time in Patients Recently Diagnosed with Axial Spondyloarthritis? A 2-Year Follow-Up Study in the SPACE Cohort
Miranda van Lunteren¹, Robert B.M. Landewé ², Camilla Fongen ³, Roberta Ramonda ⁴, Désirée van der Heijde ¹ and Floris van Gaalen ¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Amsterdam University Medical Center, Amsterdam, Netherlands, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴University of Padova, Padova, Italy
Background/Purpose: We have previously shown that in patients with recently diagnosed axial SpA (axSpA), illness perceptions had a negative impact on the relationship between back…
Abstract Number: 837 • 2019 ACR/ARP Annual Meeting
Does Discordance Between Baseline Patient’s and Evaluator’s Global Assessment of Disease Activity Impact Retention and Remission Rates of a First TNF Inhibitor in Patients with Axial Spondyloarthritis? Data from the EuroSpA Research Collaboration Network
Brigitte Michelsen¹, Lykke Midtbøll Ørnbjerg ², Anne Gitte Loft ³, Tore Kvien ⁴, Adrian Ciurea ⁵, Herman Mann ⁶, Kari K. Eklund ⁷, Ayten Yazici ⁸, Maria José Santos ⁹, Johan Askling ¹⁰, Ziga Rotar ¹¹, Bjorn Gudbjornsson ¹², Manuel Pombo-Suarez ¹³, Catalin Codreanu ¹⁴, Irene van der Horst-Bruinsma ¹⁵, Eirik Kristianslund ¹⁶, Michael J. Nissen ¹⁷, Karel Pavelka ⁶, Nina Trokovic ¹⁸, Nevsun Inanc ¹⁹, Elsa Vieira-Sousa ²⁰, Daniela DiGuiseppe ²¹, Matija Tomsic ²², Arni Jon Geirsson ²³, Ruxandra IONESCU ²⁴, Marleen van de Sande ²⁵, Florenzo Iannone ²⁶, Carlos Sánchez-Piedra ²⁷, Gareth Jones ²⁸, Lise Hyldstrup ², Merete Lund Hetland ²⁹ and Mikkel Østergaard ³⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark/ Hospital of Southern Norway Trust, Kristiansand, Norway/ Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, ²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ³Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, ⁴Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, ⁵University Hospital Zürich, Zürich, Switzerland, ⁶Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, ⁷ROB-FIN registry, Department of Medicine, Helsinki University and University Hospital, Helsinki, Finland, ⁸Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, ⁹Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ¹⁰Karolinska Institutet, Stockholm, Sweden, ¹¹UMC LJUBLJANA, DPT. OF RHEUMATOLOGY, LJUBLJANA, Slovenia, ¹²Centre for Rheumatology Research, Landspitali and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ¹³Unit Research, Spanish Society of Rheumatology, Madrid, Spain, ¹⁴Center of Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, Romania., Bucharest, Romania, ¹⁵Amsterdam University Medical Center, Amsterdam, Netherlands, ¹⁶Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Oslo, Norway, ¹⁷University Hospital Geneva, Geneva, Switzerland, ¹⁸Helsinki University Central Hospital, Helsinki, Finland, ¹⁹Marmara University, Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, ISTANBUL, Turkey, ²⁰Rheumatology and Metabolic Bone Diseases, Hospital de Santa Maria - Centro Hospitalar Lisboa Norte, EPE | Rheumatology Research Unit, Instituto de Medicina Molecular - Faculty of Medicine, University of Lisbon, Lisbon Academic Medical Centre, Lisbon, Portugal,, Lisbon, Portugal, ²¹Clinical Epidemiology Division, Dept of Medicine Solna, Karolinska Institutet,, Stockholm, Sweden, ²²Department of Rheumatology, University Medical Center Ljubljana, Slovenia, Ljubljana, Slovenia, ²³Centre for Rheumatology Research, University Hospital and Faculty of Medicine, Reykjavik, Iceland, ²⁴SPITALUL CLINIC SFANTA MARIA, Bucharest, ²⁵Amsterdam UMC, Amsterdam, Netherlands, ²⁶Department of Emergency and Transplantation , Rheumatology Unit, University Hospital of Bari, Bari, Italy., Bari, Italy, ²⁷Research Unit, Spanish Society of Rheumatology, Madrid, Spain, ²⁸University of Aberdeen, Aberdeen, United Kingdom, ²⁹DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ³⁰Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Discordance between baseline patient’s and evaluator’s global assessment of disease activity is common.1 However, the impact of such discordance on retention and remission rates…
Abstract Number: 1491 • 2019 ACR/ARP Annual Meeting
Long-term Clinical Outcome of Anti-TNF Treatment in Patients with Early Axial Spondyloarthritis: 10-year Data of the Etanercept vs. Sulfasalazin in Early Axial Spondyloarthritis Trial
Fabian Proft¹, Murat Torgutalp ², Anja Weiß ³, Mikhail Protopopov ⁴, Valeria Rios Rodriguez ⁵, Hildrun Haibel ¹, Olaf Behmer ⁶, Joachim Sieper ¹ and Denis Poddubnyy ⁷, ¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ²Charité Universitätsmedizin Berlin, Germany and Ankara University Faculty of Medicine, Ankara, Turkey., Berlin, Germany, ³German Rheumatism Research Center (DRFZ), Berlin, Germany, ⁴Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ⁵Charité Universitätsmedizin, Berlin, Germany, ⁶Pfizer Inc., Berlin, Germany, ⁷Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: Long-term data on anti-TNF treatment in patients with early axial spondyloarthritis (SpA) is scarce. The objective of this analysis was to assess the long-term…
Abstract Number: 1549 • 2019 ACR/ARP Annual Meeting
Primary 1-Year Data of Ixekizumab in Biologic Disease-Modifying Anti-rheumatic Drug-Naïve Patients with Radiographic Axial Spondyloarthritis Including Data in Patients Rerandomized from Adalimumab to Ixekizumab
Cheng-Chung Wei¹, Lianne Gensler ², Jessica Walsh ³, Robert B.M. Landewé ⁴, Tetsuya Tomita ⁵, Fangyi Zhao ⁶, Gaia Gallo ⁶, Hilde Carlier ⁷ and Maxime Dougados ⁸, ¹Chung Shan Medical University, Taichung City, Taiwan (Republic of China), ²University San Francisco California, San Francisco, CA, ³Division of Rheumatology, University of Utah, Salt Lake City, UT, ⁴Amsterdam University Medical Center, Amsterdam, Netherlands, ⁵Osaka University Graduate School of Medicine, Osaka, Japan, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Eli Lilly and Company, Indianapolis, ⁸Hôpital Cochin, Paris, France
Background/Purpose: During 16 weeks of blinded treatment, ixekizumab (IXE) and an adalimumab (ADA) active reference arm were found superior to placebo (PBO) in improving signs…
Abstract Number: 2778 • 2019 ACR/ARP Annual Meeting
Alcohol Consumption as a Predictor of the Progression of Spinal Structural Damage in Axial Spondyloarthritis: Data from the Catholic Axial Spondyloarthritis COhort (CASCO)
Hong Ki Min¹, Seung-Ki Kwok ² and Sang-Heon Lee ¹, ¹Konkuk university medical center, Seoul, Republic of Korea, ²Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Background/Purpose: The purpose of the present study was to demonstrate the predicting factors of spinal structural damage in axial spondyloarthritis (axSpA) in a prospective cohort…
Abstract Number: 568 • 2019 ACR/ARP Annual Meeting
Understanding mNY Radiograph Score Discordance in Axial Spondyloarthritis Clinical Trials Using Imaging Criteria for Subject Eligibility
Farhan Syed¹, Kassel Fotinos-Hoyer ², Michael O'Connor ³, Maureen Li ³, Bryan Hermannsson ², Nicholas Enus ³, Sayali Karve ³, Manish Sharma ⁴, Gabriele Pradella ³, Robert B.M. Landewé ⁵, Xenofon Baraliakos ⁶ and Sarah Warner ³, ¹Parexel, Billerica, MA, ²Parexel, Berlin, Germany, ³Parexel, Billerica, ⁴Parexel, Hyderabad, India, ⁵Amsterdam University Medical Center, Amsterdam, Netherlands, ⁶Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) is typically radiographically confirmed on the sacroiliac joint (SIJ) as assessed by the modified New York (mNY) criteria. In clinical trials,…
Abstract Number: 606 • 2019 ACR/ARP Annual Meeting
Effectiveness of TNFi After a First Switch in Patients with Early Axial Spondyloarthritis: A Longitudinal Analysis of the DESIR Cohort
Marion Pons ¹, Sylvie Chevret ², Karine Briot ³, Maria-Antonietta D’Agostino ⁴, Christian Roux ⁵, Maxime Dougados ⁶ and Anna Moltó⁵, ¹Rheumatology department, Cochin Hospital, Paris, Paris, Ile-de-France, France, ²INSERM U-1153, CRESS Paris-Sorbonne, Paris, Paris, Ile-de-France, France, ³Rheumatology department, Cochin Hospital, Paris, France, Paris, Ile-de-France, France, ⁴Department of Rheumatology, APHP, Hôpital Ambroise Paré, Paris, France, ⁵Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁶Cochin Hospital, Paris, France
Background/Purpose: Contradictory data has been reported on the effectiveness of a second and third line of TNFi in early axial spondyloarthritis (axSpA). The objective of…

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