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Abstracts tagged "axial spondyloarthritis"

  • Abstract Number: 1831 • 2017 ACR/ARHP Annual Meeting

    A Positive MRI of the Sacroiliac Joints Is Not Specific for Axial Spondyloarthritis but Frequently Occurs in Healthy Individuals

    Janneke de Winter1, Manouk de Hooge2, Marleen van de Sande1, Lonneke van Hoeven3, Jet de Jong1, Anoek de Koning2, Inger Jorid Berg4, Roberta Ramonda5, Dominique Baeten1,6, Désirée van der Heijde7, Angelique Weel8 and Robert B.M. Landewé9, 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, 6UCB Pharma, Slough, United Kingdom, 7Leiden University Medical Center, Leiden, Netherlands, 8Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 9Amsterdam Rheumatology & Immunology Center, Academic Medical Center, Amsterdam, Netherlands

    Background/Purpose: Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%) but the specificity is not well known, hence we compared…
  • Abstract Number: 1877 • 2017 ACR/ARHP Annual Meeting

    The Performance of MRI Using the 3D Volumetric Interpolated Breath-Hold Sequence (VIBE) Technique to Detect Structural Changes in Patients with Early Axial Spondyloarthritis in Comparison to Conventional Radiography and Computed Tomography

    Xenofon Baraliakos1, Florian Hoffmann1, Xiaohu Deng2, Yanyan Wang3, Feng Huang4 and Jürgen Braun5, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Chinese PLA General Hospital, Chinese PLA General Hospital, Beijing, China, 3Rheumatology, Chinese PLA General Hospital, Beijing, China, 4Chinese PLA General Hospital, Beijing, China, 5Institut für angewandte Statistik Dr. Jörg Schnitker GmbH, Bielefeld, Germany

    Background/Purpose: Magnetic resonance imaging (MRI) is the gold standard for detection of inflammation in the sacroiliac joints (SIJ) of patients (pts) with axial spondyloarthritis (axSpA),…
  • Abstract Number: 2438 • 2017 ACR/ARHP Annual Meeting

    Open Label Transitioning from Originator Etanercept to Biosimilar SB4 Compared to Continuing Treatment with Originator Etanercept in a Historical Cohort in Rheumatic Diseases in Daily Practice

    L. Tweehuysen1, V.J.B. Huiskes2, B.J.F. Van den Bemt (PharmD, PhD)3, S. Teerenstra4, F.H.J. van den Hoogen5, C.H.M. van den Ende5 and A.A. Den Broeder5, 1Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 2Pharmacy, Sint Maartenskliniek, Nijmegen, Netherlands, 3Pharmacy, Sint Maartenskliniek and Radboudumc, Nijmegen, Netherlands, 4Biostatistics, Radboudumc, Nijmegen, Netherlands, 5Rheumatology, Sint Maartenskliniek and Radboudumc, Nijmegen, Netherlands

    Background/Purpose: Blinded transitioning from originator infliximab (INX) to biosimilar CT-P13 was not inferior to continuing INX treatment.1 Open label mandatory transitioning resulted in a  slightly…
  • Abstract Number: 2500 • 2017 ACR/ARHP Annual Meeting

    Are Work Outcomes Improved in Axial Spondyloarthritis (axSpA) Patients with Biologic Therapy? Results from the British Society for Rheumatology Register

    Gary J. Macfarlane, Gareth T. Jones and Joanna Shim, Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom

    Background/Purpose: Patients with axial spondyloarthritis (axSpA) identify the ability to stay at work as a priority. Biologic therapy improves disease activity and quality of life…
  • Abstract Number: 2501 • 2017 ACR/ARHP Annual Meeting

    Potential Differences in Axial Spondyloarthritis Disease Activity Categorization Using Different Minimum Values for High-Sensitivity CRP in Ankylosing Spondylitis Disease Activity Score Calculation and Different Definitions of Disease Flare

    Robert B.M. Landewé1, Joachim Sieper2, Uta Kiltz3, Xin Wang4, Mei Li4 and Jaclyn K. Anderson4, 1University of Amsterdam, Amsterdam, Netherlands, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4AbbVie Inc., North Chicago, IL

    Background/Purpose: It has been recommended that the lower limit of high-sensitivity CRP (hsCRP) be restricted to 2 in the Ankylosing Spondylitis Disease Activity Score (ASDAS)…
  • Abstract Number: 581 • 2017 ACR/ARHP Annual Meeting

    Diagnostic Value of Anti-CD74 Antibodies in Early Axial Spondyloarthritis: Data from the Spondyloarthritis Caught Early (SPACE) Cohort

    Janneke de Winter1, Marleen van de Sande1, Niklas Thomas Baerlecken2, Inger Berg3, Roberta Ramonda4, Désirée van der Heijde5, Floris van Gaalen6, Torsten Witte7 and Dominique Baeten1,8, 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Center, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 2Rheumatology, Private Practice, Cologne, Germany, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, 5Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Leiden University Medical Center, Leiden, Netherlands, 7Clinical Immunology and Rheumatology, Medical University Hannover, Hanover, Germany, 8UCB Pharma, Slough, United Kingdom

    Background/Purpose: Anti-CD74 IgG antibodies are reported to be elevated in serum of patients with axial spondyloarthritis (axSpA). This study aimed to assess the diagnostic value…
  • Abstract Number: 2504 • 2017 ACR/ARHP Annual Meeting

    The Validation of Istanbul  Back Disability Index (IBDI) in Axial Spondyloarthritis Patients

    Tuncay Duruoz, Hatice Sule Baklacioglu, Sevtap Acer Kasman and Didem Erdem, PMR Department, Rheumatology Division, Marmara University School of Medicine, Istanbul, Turkey

    Background/Purpose: The IBDI was developed to assess the disability in patients with mechanical low back pain (1) which contains the 18 daily activities questions. The…
  • Abstract Number: 584 • 2017 ACR/ARHP Annual Meeting

    Factors Associated with the “Bamboo Spine” Phenotype – Data from the Comospa Study

    Koei Oh1, Anna Molto2, Corinne Miceli-Richard3, Soksay Singvongsa4, Adrien Etcheto4 and Maxime Dougados4, 1Departmen of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France, 2Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, 3Department of Rheumatolgy, Paris Descartes University, Hôpital Cochin, Paris, France, 4Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France

    Background/Purpose: The factors associated with “Bamboo spine” occurrence, i.e. the most severe axial phenotype of SpA patients, have been poorly assessed to date. The aim…
  • Abstract Number: 2514 • 2017 ACR/ARHP Annual Meeting

    When Should Lateral Dexa be Used to Measure Spine Bone Mineral Density in Axial Spondyloarthritis Patients: A Cross-Sectional Study

    Sizheng Zhao1,2, Daniel Thong3, Eleanor Quilliam2, Stephen Duffield1, Kai-Wei Yin3 and Nicola Goodson1,2, 1Musculoskeletal Biology 1 Department, University of Liverpool, Liverpool, United Kingdom, 2Aintree University Hospital, Liverpool, United Kingdom, 3University of Liverpool, Liverpool, United Kingdom

    Background/Purpose: Osteoporosis and vertebral fractures are recognized complications in axial spondyloarthritis (axSpA). Anteroposterior (AP) DEXA is commonly used to assess spinal bone mineral density (BMD)…
  • Abstract Number: 1164 • 2016 ACR/ARHP Annual Meeting

    Impact of E-Learning on Knowledge, Self-Efficacy and Exercise Behaviours of Patients with Axial Spondyloarthritis: Results from a Longitudinal Randomized Control Trial

    Laura Passalent1,2, Rita Kang3, Daeria Lawson4, Christopher Hawke1,5, Ahmed Omar6,7, Arane Thavaneswaran4, Nigil Haroon8,9 and Robert D Inman7,10, 1Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 2Physical Therapy, University of Toronto, Toronto, ON, Canada, 3Patient and Family Education, Toronto Western Hospital, Toronto, ON, Canada, 4Toronto Western Hospital, Toronto, ON, Canada, 5Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, 6Rheumatology, University of Toronto, Toronto, ON, Canada, 7Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 8Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 9Medicine, Rheumatology, University of Toronto, Toronto, ON, Canada, 10University of Toronto, Toronto, ON, Canada

    Background/Purpose:  There is a growing body of evidence to support the effectiveness of education programs for patients with arthritis. Despite this, there has been little development…
  • Abstract Number: 1240 • 2016 ACR/ARHP Annual Meeting

    A Minority of Patients Utilize Most of Healthcare Resources in Rheumatoid Arthritis, Psoriatic Arthritis, Juvenile Idiopathic Arthritis, and Axial Spondyloarthritis

    Nina Mars1, Anne M Kerola2, Markku J Kauppi3,4, Outi Elonheimo5,6, Santeri Huvinen5,6 and Tuulikki Sokka-Isler7,8, 1University of Helsinki, Helsinki, Finland, 2Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, 3School of Medicine, University of Tampere, Tampere, Finland, 4Department of Rheumatology, Päijät-Häme Central Hospital, Lahti, Finland, 5Network of Academic Health Centres, Department of Medicine, University of Helsinki, Helsinki, Finland, 6FCG Finnish Consulting Group Ltd., Helsinki, Finland, 7Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland, 8RAID working group for EULAR, Zurich, Switzerland

    Background/Purpose: Rheumatoid arthritis (RA) is associated with high healthcare costs, but little is known about how the costs compare to other chronic rheumatic diseases. We…
  • Abstract Number: 1292 • 2016 ACR/ARHP Annual Meeting

    Performance of 18fluoride Sodium Positron Emission Tomography with Computed Tomography to Assess Inflammatory and Structural Sacroiliitis Respectively on Magnetic Resonance Imaging and Computed Tomography in Axial Spondyloarthritis

    Marie Raynal1, ouichka remy2, Julian Melchior1, Isabelle Chary-Valckenaere3, Willy Ngueyon Sime4, Walter P. Maksymowych5, Robert G. Lambert6 and Damien Loeuille3, 1Rheumatology, CHRU Nancy, Nancy, France, 2rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 3Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 4University of Lorraine, Nancy, France, 5Medicine, University of Alberta, Edmonton, AB, Canada, 6Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: to assess increased SIJ uptakes on 18-FNa (an osteoblastic tracer) PET/CT according to a qualitative and quantitative approach and to compare with MRI SIJ…
  • Abstract Number: 1667 • 2016 ACR/ARHP Annual Meeting

    Diagnostic Value of Anti-CD74 Antibodies in Axial Spondyloarthritis: Results from a Population with Low HLA-B27 Prevalence Background

    Nelly Ziade1, Fouad Fayad1, Iyad Mallak2, Georges Merheb3, Torsten Witte4 and Xenofon Baraliakos5, 1Rheumatology, Hotel Dieu de France Hospital and Saint Joseph University, Beirut, Lebanon, 2Radiology, Hotel-Dieu de France and Saint-Joseph University, Beirut, Lebanon, 3Internal Medicine, Notre Dame des Secours University Hospital, Jbeil, Lebanon, 4Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany, 5Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is still frequently diagnosed late and its pathogenesis is still unclear. Although a strong genetic association of axSpA with HLA-B27 is…
  • Abstract Number: 1731 • 2016 ACR/ARHP Annual Meeting

    Disease Burden and Impact of Certolizumab Pegol Treatment on Workplace and Household Productivity Across Working Age Rheumatoid Arthritis, Psoriatic Arthritis and Axial Spondyloarthritis Patients

    Arthur F. Kavanaugh1, Philip J. Mease2, Oana Purcaru3 and Désirée van der Heijde4, 1Division of Rheumatology, Allergy, and Immunology, UC San Diego School of Medicine, La Jolla, CA, 2Swedish Medical Center and University of Washington, Seattle, WA, 3208 Bath Road, UCB Pharma, Slough, United Kingdom, 4Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Inflammatory diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), including ankylosing spondylitis (AS) and non-radiographic axSpA (nr-axSpA), can impact…
  • Abstract Number: 1732 • 2016 ACR/ARHP Annual Meeting

    Articular and Axial Involvement Differences in Psoriatic Arthritis Patients Treated with Golimumab in Canadian Real-World Practice

    Majed M. Khraishi1, Proton Rahman2, Alexander Tsoukas3, Suneil Kapur4, Milton F. Baker5, Niall Jones6, Michael Starr7, Emmanouil Rampakakis8, Eliofotisti Psaradellis9, Karina Maslova10, Francois Nantel11, Allen J Lehman10, Cathy Tkaczyk12 and Brendan Osborne12, 1Nexus Clinical Research, St Johns, NF, Canada, 2Rheumatology, St Claires Mercy Hospital, St Johns, NF, Canada, 3McGill University, Montreal, QC, Canada, 4University of Ottawa, 139 Greenbank Rd, Suite 203, ON, Canada, 5VIHA, Victoria, BC, Canada, 6University of Alberta, Edmonton, AB, Canada, 7McGill University, Pointe-Claire, QC, Canada, 8JSS Medical Research, St-Laurent, QC, Canada, 9JSS Medical Research, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 1119 Green belt Dr, Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: Psoriatic arthritis (PsA) is a complex rheumatic disease with severity that ranges from mild to severe. The mild form of PsA can be referred…
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