ACR Meeting Abstracts

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Abstracts tagged "autoimmune diseases"

  • Abstract Number: 0866 • ACR Convergence 2020

    Identifying an SLE Patient Cluster with Greater Treatment Effect: Immune Cell Deconvolution of Gene Expression in Two Atacicept Phase II Studies

    Joan Merrill1, Matthew Studham2, Eric Morand3, Aida Aydemir2, Cristina Vazquez Mateo2, Alex Rolfe2, Amy Kao2 and Robert Townsend2, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2EMD Serono (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 3Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia

    Background/Purpose: Atacicept, a dual inhibitor of the B lymphocyte stimulator and a proliferation-inducing ligand (APRIL), has been associated with a reduction of flares in the…
  • Abstract Number: 1054 • ACR Convergence 2020

    Treatment with Certolizumab Pegol in Refractory Uveitis Secondary to Inmune-Mediated Inflammatory Diseases. Multicenter Study of 39 Patients

    José Luis Martín-Varillas1, Vanesa Calvo-Río2, Lara Sanchez-Bilbao2, Inigo Gonzalez-Mazon3, Ignacio Torre4, Alvaro García Martos5, Amalia Sánchez Andrade6, Angel García Aparicio7, Juan Ramón De dios8, Ana Urriticoechea9, Olga Maiz Alonso10, Raul Veroz11, Andrea García Valle12, Sergio Rodriguez Montero13, Roberto Miguelez14, Vega Jovani15, Marisa Hernandez Garfella16, Arantxa Conesa17, Olga Martinez Gonzalez18, Paula Rubio Muñoz19, Eva Peña Sainz-Pardo20, Miguel Ángel González-Gay21 and Ricardo Blanco2, 1Hospital Sierrallana, Torrelavega, Spain, 2Hospital Universitario Marques de Valdecilla, Santander, Spain, 3Hospital Universitario Marques de Valdecilla, Bezana, Spain, 4Hospital Basurto, Bilbao, Spain, 5Hospital del Tajo, Madrid, Spain, 6H. Lucus Augusti, Lugo, Spain, 7H. Mostoles, Madrid, Spain, 8H. Alava, Alava, Spain, 9Can Misses, Ibiza, Spain, 10Hospital Universitario Donostia, San Sebastian, Pais Vasco, Spain, 11H. Mérida, Mérida, Spain, 12H. Palencia, Palencia, Spain, 13H. Virgen de Valme, Sevilla, Spain, 14Toledo, Toledo, Spain, 15H. Alicante, Alicante, Spain, 16H. Valencia, Valencia, Spain, 17H. Castellón, Castellón, 18H. Salamanca, Salamanca, 19H. Esperit Sant, Barcelona, Spain, 20H. 12 de Octubre, Madrid, Spain, 21Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Infliximab and adalimumab therapy has significantly improved the prognosis of patients with non-infectious refractory uveitis. However, there is not enough evidence for the use…
  • Abstract Number: 1379 • ACR Convergence 2020

    Clinical Outcomes Among Participants with Diffuse Systemic Sclerosis Contracting COVID-19 During Clinical Studies of Lenabasum: A Case Series

    Robyn Domsic1, Lorinda Chung2, Jerry Molitor3, Robert Spiera4, Bradley Bloom5, Barbara White6 and Quinn Dinh6, 1University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA, 3University of Minnesota, Minneapolis, MN, 4Division of Rheumatology, Hospital for Special Surgery, New York, New York, USA, New York, NY, 5Corbus Pharmaceuticals Inc, Norwood, MA, 6Corbus Pharmaceuticals, Norwood, MA

    Background/Purpose: Patients with systemic sclerosis (SSc) may be at increased risk for severe outcomes with COVID-19, given the high rate of immunosuppressive medication use, underlying…
  • Abstract Number: 1478 • ACR Convergence 2020

    A Multidisciplinary Registry of Patients with Autoinmune and Immune-Mediated Diseases with Symptomatic COVID-19 Infection from a Single Center

    Juan C Sarmiento-Monroy1, Gerard Espinosa2, Fernanda Meira1, Berta Caballol3, Maria C Londoño3, Sara Llufriu3, Aina Moll1, Luis Fernando Quintana Porras1, Felipe Julio Ramirez Garcia4, José Inciarte-Mundo1, Elisabeth Solana1, Yolanda Blanco1, Eugenia Martinez1, Victor Llorens1, Sergio Prieto-González5, Georgina Espigol1, Jose C Milisenda1, Maria C. Cid5, Priscila Giavedoni1, Jose M Mascaró1, Isabel Blanco1, Joan Albert Barbera1, Oriol Sibila1, Jordi Gratacos-Gines1, Alfredo Adan2, Alvaro Agustí1, Raimon Sanmartí6, Julián Panés1, Ricard Cervera1, Jordi Vila1, Alex Soriano1, Jose Gómez-Puerta6 and On behalf INMUNOCOVID CLINIC7, 1Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, 2Hospital Clinic, Barcelona, Catalonia, Spain, 3Hospital Clinic de Barcelona, Barcelona, Spain, 4Arthritis Unit, Rheumatology Dpt, Hospital Clinic, Barcelona, Spain, Barcelona, Catalonia, Spain, 5Vasculitis Research Unit, Department of Systemic Autoimmune Diseases, Hospital Clínic de Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain., Barcelona, Catalonia, Spain, 6Hospital Universitari Clínic de Barcelona, Barcelona, Catalonia, Spain, 7Hospital Clinic de Barcelona, Barcelona

    Background/Purpose: National health authorities reported a prevalence of SARS-CoV-2 infection around 7% of the general population in Barcelona county (1). A recent report focused on…
  • Abstract Number: 1802 • ACR Convergence 2020

    Vitamin D Level: Predictor of SLE Disease Activity in AA Cohort with CLE?

    Ileannette Robledo-Vega1, John Scheinuk2, Emmanuel Pardo2, Ansley Pratt2, Soham Mahato3, Andrew G. Chapple2 and Myriam Guevara4, 1Louisiana State University Health Sciences Center, New Orlenas, LA, 2Louisiana State University, New Orleans, LA, 3LSUHSC School of Public Health, New Orleans, LA, 4Lousiana State University Health Sciences Center, New Orleans, LA

    Background/Purpose: There are few predominant African American (AA) epidemiological studies in Cutaneous Lupus Erythematosus (CLE). The Gilliam classification divides CLE into lupus specific, acute cutaneous…
  • Abstract Number: PP06 • ACR Convergence 2020

    Only in My Dreams Can I Do the Things I Used to Do: Where There Is Research, There Is Hope

    Dan Smith1, Robert Smith1 and Jillian Covault1, 1Canton, MI

    Background/Purpose: In Mach 2020, I was diagnosed with relapsing polychondritis ("RP"), a multisystem, rheumatologic disease characterized by inflammation of cartilaginous structures including the ear, nose,…
  • Abstract Number: 0081 • ACR Convergence 2020

    Prevalence of Systemic Autoimmune Diseases in Polycystic Ovary Syndrome

    Saika Sharmeen1, Hafsa Nomani2, Erin Taub3 and Qingping Yao3, 1Stony Brook University Renaissance School of Medicine, Dix Hills, NY, 2Stony Brook University Renaissance School of Medicine, West Babylon, NY, 3Stony Brook University Renaissance School of Medicine, Stony Brook, NY

    Background/Purpose: Polycystic ovary syndrome (PCOS) is characterized by hormonal abnormality, chronic anovulation, hyperandrogenism, and obesity. Due to the hormonal imbalance, we hypothesize that patients with…
  • Abstract Number: 0430 • ACR Convergence 2020

    Outcomes of Coronavirus Disease 2019 Infection Among Patients Living with Rheumatic Diseases: A Matched Cohort Study from a US Multi-Center Research Network

    Kristin D'Silva1, April Jorge1, Na Lu2, Yuqing Zhang3, Zachary Wallace4 and Hyon Choi5, 1Massachusetts General Hospital, Boston, MA, 2Arthritis Research Canada, Vancouver, BC, Canada, 3Massachusetts General Hospital, Quincy, MA, 4Massachusetts General Hospital, Newton, MA, 5Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA

    Background/Purpose: Whether patients living with systemic autoimmune rheumatic diseases (SARDs) suffer from more severe complications of Coronavirus Disease 2019 (COVID-19) infection remains unknown.Methods: We conducted…
  • Abstract Number: 0607 • ACR Convergence 2020

    The Evolution of Rheumatologist’s Practice in Response to the COVID19 Pandemic

    Maria Bacalao1, Kathryn Dao2 and John Cush2, 1UT Southwestern, Dallas, TX, 2University of Texas Southwestern Medical School, Dallas, TX

    Background/Purpose: The COVID19 pandemic was a turning point for Rheumatology. This survey of rheumatologists (rheums) assessed its impact on care delivery, patient counseling and drug…
  • Abstract Number: 0955 • ACR Convergence 2020

    Efficacy and Safety of IVIg (Octagam 10%) in Patients with Active Dermatomyositis. Results of a Randomized, Double-Blind, Placebo-Controlled Phase III Trial (ProDERM Study)

    Rohit Aggarwal1, Christina Charles-Schoeman2, Joachim Schessl3, Zsuzsanna Bata-Csorgo4, Mazen Dimachkie5, Zoltan Griger6, Sergey Moiseev7, Chester Oddis8, Elena Schiopu9, Jiří Vencovský10, Beckmann Irene11, Clodi Elisabeth11, Todd Levine12 and and the ProDERM Investigators13, 1University of Pittsburgh, Pittsburgh, PA, 2University of California, Los Angeles, Los Angeles, CA, 3Städtisches Klinikum Karlsruhe, Karlsruhe, Germany, 4University of Szeged, Faculty of Medicine, Szeged, Hungary, 5Univeristy of Kansas, Medical Center, Kansas City, KS, 6University of Debrecen, Debrecen, Hungary, 7First Moscow State Medical University, Moscow, Russia, 8Department of Medicine, Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 9Michigan Medicine, Ann Arbor, MI, 10Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 11Octapharma Pharmazeutika Produktionsges.m.b.H., Vienna, Austria, 12Phoenix Neurological Associates, LTD, Phoenix, AZ, 13Different Institutions in several countries, Vienna, Austria

    Background/Purpose: Dermatomyositis (DM) is a rare chronic systemic autoimmune disease with characteristic skin rash and progressive proximal muscle weakness. Intravenous immunoglobulin (IVIg) has long been…
  • Abstract Number: 1065 • ACR Convergence 2020

    Immunostimulatory Herbal Supplement Use Is More Common Among Patients with Dermatomyositis

    Adarsh Ravishankar1, Daisy Yan2, Christina Bax3, Josef Symon Concha2, Bridget Shields4, Lisa Pappas-Taffer4, Rui Feng5, Joyce Okawa4 and Victoria Werth2, 1University of Pennsylvania and the Michael J. Crescenz VA Medical Center, Philadelphia, 2University of Pennsylvania and the Michael J. Crescenz VA Medical Center, Philadelphia, PA, 3University of Pennsylvania, Department of Dermatology, Philadelphia, 4Department of Dermatology, University of Pennsylvania, Philadelphia, PA, 5University of Pennsylvania, Philadelphia

    Background/Purpose: The use of complementary and alternative medicine (CAM) is prevalent in dermatology. Certain CAMs, including Spirulina, Alfalfa, Chlorella, Echinacea, and Blue-Green Algae have been…
  • Abstract Number: 1397 • ACR Convergence 2020

    Clinical and Demographic Features of Morphea Patients with Mucocutaneous Involvement: A Cross Sectional Study from the Morphea of Adults and Children Cohort

    Smriti Prasad1, Samantha Black2, Shivani Sharma3 and Heidi Jacobe1, 1University of Texas Southwestern Medical Center, Dallas, TX, 2The University of Texas Southwestern Medical Center, Dallas, TX, 3University of Texas Southwestern, Dallas, TX

    Background/Purpose: Morphea is an autoimmune skin condition that produces skin and soft tissue sclerosis. While clinical manifestations of morphea have been well-described, mucocutaneous findings such…
  • Abstract Number: 1560 • ACR Convergence 2020

    Measuring Asymmetry in Facial Morphea via 3D Stereophotogrammetry

    Laila Abbas1, Jennifer Day2 and Heidi Jacobe3, 1UT Southwestern Medical Center, Dallas, TX, 2University of Colorado, Denver, CO, 3University of Texas Southwestern Medical Center, Dallas, TX

    Background/Purpose: Morphea is an autoimmune disorder causing sclerosis and inflammation of the skin and subcutaneous tissue. Facial morphea can cause substantial disfigurement and negative impact on quality of life. Existing clinical measures such…
  • Abstract Number: 1820 • ACR Convergence 2020

    Serum α-Klotho Is Decreased in Older Systemic Lupus Erythematosus Patients and Correlate with Markers of Disease Activity

    Margaret Markiewicz1, Dayvia Russell2 and Jim Oates1, 1Medical University of South Carolina, Charleston, SC, Charleston, SC, 2.Research Services, Ralph H. Johnson VA Medical Center, Charleston, SC,, Charleston

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, debilitating autoimmune disease characterized by heterogeneous, multiorgan involvement with female predominance. Lupus nephritis is one of the…
  • Abstract Number: PP07 • ACR Convergence 2020

    Improving Communication with My Physician Drastically Improved My Health

    Whitney Carter1, 1Lupus and Allied Diseases Association, Inc., Pleasanton, CA

    Background/Purpose: In 2011, at the age of 14, I was sent to the emergency room with a platelet count of 19. The hematologist diagnosed me…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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