Abstracts tagged "autoantibodies"

Abstract Number: 2301 • 2012 ACR/ARHP Annual Meeting
The Interferon Type I Signature Is Increased in Monocytes From Systemic Sclerosis Patients
Zana Brkic¹, Lenny van Bon², Cornelia G. van Helden-Meeuwsen³, Madelon C. Vonk⁴, Hanneke Knaapen⁵, Wim van den Berg⁵, Paul L. Van Daele³, Virgil A. Dalm¹, Timothy Radstake² and Marjan A. Versnel¹, ¹Erasmus Medical Center, Immunology, Rotterdam, Netherlands, ²Rheumatology and Clinical Immunology, University Medical Center Utrecht/Radboud University Nijmegen Medical Center, Utrecht/Nijmegen, Netherlands, ³Immunology, Erasmus Medical Center, Rotterdam, Netherlands, ⁴Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands, ⁵Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands
Background/Purpose: Systemic sclerosis (SSc) is a complex fibrosing disease of unknown etiology. The past decade clear indications for an aberrant immune system have been revealed.…
Abstract Number: 713 • 2012 ACR/ARHP Annual Meeting
Rpp25 Is a Major Target of Autoantibodies to the Th/to Complex As Measured by ELISA and a New Chemilumiscence Assay
Michael Mahler¹, Cristina Gascon², Sima Patel², Angela Ceribelli³, Edward K.L. Chan³ and Minoru Satoh⁴, ¹Research, INOVA Diagnostics, San Diego, CA, ²Research, INOVA Diagnostics, Inc., San Diego, CA, ³Oral Biology, University of Florida, Gainesville, FL, ⁴Medicine, University of Florida, Gainesville, FL
Background/Purpose: Anti-nuclear antibodies (ANA) play an important role in the diagnosis of systemic autoimmune diseases including systemic sclerosis (SSc). A significant portion of ANA in…
Abstract Number: 1664 • 2012 ACR/ARHP Annual Meeting
Autoantibodies Are Associated with Subclinical Atherosclerosis and Cardiovascular Endpoints in Caucasian and African American Women in a Prospective Study: the Multi-Ethnic Study of Atherosclerosis (MESA)
Darcy S. Majka¹, Rowland W. Chang², Richard M. Pope³, Marius C. Teodorescu⁴, Elizabeth W. Karlson⁵, Thanh Huyen T. Vu⁶, Joseph Kang⁶ and Kiang Liu⁷, ¹Division of Rheumatology, Northwestern University, Chicago, IL, ²Dept Preventive Med, Northwestern University, Chicago, IL, ³Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL, ⁴Microbiology, TheraTest Laboratories Inc, Lombard, IL, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁶Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL, ⁷Preventive Medicine, Northwestern University, Chicago, IL
Background/Purpose: Although the association between rheumatoid arthritis (RA) and cardiovascular disease (CVD) is established, the exact mechanism is not known. Subjects who later develop RA…
Abstract Number: 2380 • 2012 ACR/ARHP Annual Meeting
High Frequency of Ferritin Autoantibodies in Takayasu Arteritis
Niklas T. Baerlecken¹, Katherina Große², Frank Moosig³, Wolfgang L. Gross⁴, Reinhold E. Schmidt¹ and Torsten Witte⁵, ¹Clinical Immunology and Rheumatology, Medical University Hannover, Hannover, Germany, ²Department of Immunology and Rheumatology, Student, Hannover, Germany, ³University of Luebeck, Stormarnzing 156, Bad Bramstedt, Germany, ⁴Dept of Clinical Rheumatology, Medical University at Lubeck, Lubeck, Germany, ⁵Hannover Medical School, Hanover, Germany
Background/Purpose: Takayasu arteritis (TA) may be difficult to diagnose since diagnostic biomarkers have not been established so far. In a previous study, we could show…