ACR Meeting Abstracts

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Abstracts tagged "Atherosclerosis"

  • Abstract Number: 1788 • 2015 ACR/ARHP Annual Meeting

    Lipoprotein Subfractions and Cardiovascular Disease in Systemic Lupus Erythematosus

    Simantini Sakhardande1, Monica Purmalek1, Maureen Sampson2, Yenealem Temesgen-Oyelakim3, Alice Fike4, Taufiq Salahuddin5, Balaji Natarajan5, Zerai Manna6, Elizabeth Joyal6, Marcus Chen5, Sarfaraz Hasni6, Nehal N. Mehta5,7, Alan Remaley5 and Mariana J. Kaplan1, 1Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2CC/NIH, Bethesda, MD, 3Office of the Clinical Director,National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 5NHLBI, National Institutes of Health, Bethesda, MD, 6National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 7National Heart Lung Blood Institute, Cardiovascular and Pulmonary Division, NHLBI, National Institutes of Health, Bethesda, MD

    Background/Purpose: Risk of atherosclerotic cardiovascular disease (CVD) is significantly enhanced in systemic lupus erythematosus (SLE) compared to age and gender matched controls. While this risk…
  • Abstract Number: 1051 • 2015 ACR/ARHP Annual Meeting

    Serum Calprotectin As Biomarker of Carotid Atherosclerosis in Patients with Primary Sjögren’s Syndrome

    Gabriela Moreira Balarini1, Eliana Zandonade2, leandro tanure3, gilda Aparecida ferreira3, Wildner Mardegan Sardenberg4, Érica Vieira Serrano4, Cléia Coelho Dias5, Túlio Pinho Navarro3, João Felipe Tonini4, Hilde H Nordal6, Piotr Mydel7, Johan Gorgas Brun8, Karl Albert Brokstad9, Eva Gerdts8, Roland Jonsson10,11 and Valeria Valim4,12, 1Department of Medical Clinic, Federal University of Espírito Santo (UFES), Brazil., cachoeiro de itapemirim, Brazil, 2Department of Statistic, Federal University of Espírito Santo (UFES), Brazil., vitória, Brazil, 3Department of Locomotor System, Federal University of Minas Gerais, Brazil., belo horizonte, Brazil, 4Department of Medical Clinic, Federal University of Espírito Santo (UFES), Brazil., vitória, Brazil, 5Department of Medical Clinic, Federal University of Espírito Santo (UFES), Brazil., vila velha, Brazil, 6Broegelmann Research Laboratory/University of Bergen, Norway, bergen, Norway, 7Clinical Science, Broegelmann Research Laboratory, Bergen, Norway, 8Department of Clinical Science, University of Bergen, Norway, bergen, Norway, 9Department of Clinical Science, University of Bergen, Norway., bergen, Norway, 10Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, 11Broegelmann research laboratory, Bergen, Norway, 12Rheumatology, Universidade Federal do Espírito Santo, Vitória, Brazil

    Background/Purpose: The relationship between atherosclerosis, traditional risk factors, disease activity and biomarkers is not well explored. We aimed to identify the association of carotid atherosclerosis…
  • Abstract Number: 1791 • 2015 ACR/ARHP Annual Meeting

    Does Renin-Angiotensin System Blockade Protect Lupus Nephritis Patients from Atherosclerotic Cardiovascular Events?  a Case-Control Study

    Konstantinos Tselios1, Dafna Gladman2, Jiandong Su2 and Murray Urowitz2,3, 1Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are currently used as an adjuvant treatment in lupus nephritis (LN) patients for the…
  • Abstract Number: 1065 • 2015 ACR/ARHP Annual Meeting

    Atherosclerotic Vascular Events in a Multinational SLE Inception Cohort: Description and Predictive Risk Factors over a 15 Year Period

    Murray Urowitz1,2, Dafna Gladman1, Nicole Anderson3, Jiandong Su1 and Systemic Lupus Erythematosus International Collaborating Clinics (SLICC), 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: A large multicentre multinational inception cohort was established to study risk factors for atherosclerosis (AS) in SLE. We aim to describe all vascular events…
  • Abstract Number: 1797 • 2015 ACR/ARHP Annual Meeting

    Insulin Resistance Is Not Associated with Increased Risk of Subclinical Atheromatosis in Patients with Systemic Lupus Erythematosus from Northern Spain

    Leyre Riancho-Zarrabeitia1, Alfonso Corrales2, Nuria Vegas-Revenga1, Lucía Dominguez-Casas1, Javier Rueda-Gotor2, Montserrat Santos-Gómez1, Maria T. García-Unzueta3, Ricardo Blanco1 and Miguel Angel Gonzalez-Gay1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 2rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 3Biochemistry, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain

    Background/Purpose: Metabolic syndrome is a recently defined clustering of cardiovascular risk (CV) factors associated with insulin resistance (IR) and an increased risk of CV disease.…
  • Abstract Number: 1171 • 2015 ACR/ARHP Annual Meeting

    Plasma Soluble ST2 Levels Are Independently Associated with Both Carotid Atherosclerosis and Compromised Cortical Volumetric Bone Mineral Density and Microstructure in Patients with Psoriatic Arthritis

    Jiayun Shen1, Qing Shang1, Edmund Li1, Tracy Y. Zhu2, Ling Qin2 and Lai-Shan Tam1, 1Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, China, 2Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, China

    Background/Purpose: Patients with PsA have both increased risk of subclinical atherosclerosis and lower cortical volumetric BMD (vBMD) compared with the general population, probably as a…
  • Abstract Number: 1811 • 2015 ACR/ARHP Annual Meeting

    Depression and Progression of Subclinical Cardiovascular Disease in Systemic Lupus Erythematosus

    April Jorge1, Apinya Lertratanakul2, Julia (Jungwha) Lee3, William Pearce1, David McPherson4, Trina Thompson5, Emma Barinas-Mitchell6 and Rosalind Ramsey-Goldman1, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Chicago, IL, 3Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 4University of Texas Health Science Center, Houston, TX, 5Saint Francis University, Ebensburg, PA, 6University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Women with SLE have an increased incidence of premature cardiovascular disease (CVD). Depression is also common among SLE patients. A relationship between depression and…
  • Abstract Number: 1509 • 2015 ACR/ARHP Annual Meeting

    Serum Nitrite Levels in Rheumatoid Arthritis and Relationship to Cardiovascular Risk Factors and Atherosclerosis Biomarkers

    Kimberly P. Liang1, Douglas P. Landsittel2, Bernadette B. Sendon3, Donald M. Jones4, Rachel Gartland3, Suresh R. Mulukutla5, Steven E. Reis6, Flordeliza S. Villanueva5, Ali Hakim Shoushtari7, Cameron Dezfulian8 and Larry W. Moreland4, 1Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Medicine, University of Pittsburgh, Pittsburgh, PA, 3Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 4Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 5Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, 6Division of Cardiology and Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA, 7Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, 8Critical Care Medicine and Clinical and Translational Science, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Nitric oxide (NO) has been implicated in immune regulation, inflammation, arthritis and atherosclerosis. Raised levels of nitrite (NO2) in serum and synovial fluid have…
  • Abstract Number: 1903 • 2015 ACR/ARHP Annual Meeting

    Assessment of Subclinical Atherosclerosis in Patients with Systemic Sclerosis: Results from a Multicentric Cohort

    Codrina Ancuta1,2, Codruta Belibou3, Cristina Pomirleanu1,4, Carina Mihai5, Ioan Ancuta5, Patricia E. Carreira6, Jose Luis Rosales Alexander7, Juan José Alegre8, Valeria Riccieri9, Maria J. Salvador10 and Rodica Chirieac4, 1Rheumatology, Gr.T.Popa University of Medicine and Pharmacy, Iasi, Romania, 2Rheumatology 2, Clinical Rehablitation Hospital, Iasi, Romania, 3Research Department, Clinical Rehabilitation Hospital, Iasi, Romania, 4Rheumatology 2, Clinical Rehabilitation Hospital, Iasi, Romania, 5Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 6Multidisciplinary Pulmonary Hypertension Unit. Hospital Universitario 12 de Octubre, Madrid, Spain, 7Rheumatology, Hospiten Health Network, Tenerife, Spain, 8Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 9Cattedra di Reumatologia, Dip Clinica e Terapia Medica, Sapienza Università di Roma, Roma, Italy, 10Rheumatology, Centro Hospitalar e Universitário de Coimbra - Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal

    Background/Purpose: Although numerous studies have reported different findings on subclinical and definite atherosclerosis (AS) in autoimmune rheumatic diseases, data in systemic sclerosis (SSc) are still…
  • Abstract Number: 1523 • 2015 ACR/ARHP Annual Meeting

    Ischemia Modified Albumin Levels in Rheumatoid Arthritis

    Ali Ugur Uslu1, Adem Kucuk2, Sevket Balta3, Sevket Arslan4, Levent Tekin5, Sami Kucuksen6, Aysun Toker7 and Mehmet Kayrak8, 1Internal Medicine, Eskisehir Military Hospital, Eskisehir, Turkey, 2Necmettin Erbakan U Meram T F, Necmettin Erbakan U Meram T F, Konya, Turkey, 3Cardiology, Eskisehir Military Hospital, Eskisehir, Turkey, 4Allergy and Clinical Immunology, Necmettin Erbakan University, Konya, Turkey, 5Physical Medicine and Rehabilitation, Beyhekim State Hospital, Konya, Turkey, 6MD, kONYA, Turkey, 7Biochemistry, Necmettin Erbakan University, Konya, Turkey, 8Necmettin Erbakan University, Division of Cardiology, Konya, Turkey

    Background/Purpose:  Cardiovascular diseases, among which atherosclerotic heart disease, are known to be one of the most important mortality and morbidity causes in patients with Rheumatoid…
  • Abstract Number: 2003 • 2015 ACR/ARHP Annual Meeting

    Primary Antiphospholipid Syndrome Is Characterized By Endothelial Progenitor Dysfunction and a Type I Interferon Signature

    Robert C. Grenn1, Srilakshmi Yalavarthi2, Paula L. Bockenstedt3 and Jason S. Knight2, 1University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI, 3Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI

    Background/Purpose:  Patients with primary antiphospholipid syndrome (APS) are at risk for endothelial dysfunction and accelerated atherosclerosis.  In systemic lupus erythematosus (SLE), there is a well-established…
  • Abstract Number: 1536 • 2015 ACR/ARHP Annual Meeting

    Sensorineural Hearing Impairment and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients without Traditional Cardiovascular Risk Factors

    Hector Macias Reyes1, Sergio Duran-Barragan2,3, Cynthia Cardenas Contreras4, Cesar Chavez Martin4, Eduardo Gomez2, Rosa Navarro Hernandez2, Jorge Aguilar Arreola2,5, Paul Perez-Cruz2,5, Carlos Yanowsky Gonzalez2 and Monica Vazquez-Del Mercado2,5, 11. Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, 2Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Instituto de Investigación en Reumatología y del Sistema Musculoesquelético, Guadalajara, Mexico, 3Clinica de Investigación en Reumatología y Obesidad, Guadalajara, Mexico, 4Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, 5Servicio de Reumatología, División de Medicina Interna, Hospital Civil Dr. Juan I. Menchaca, Guadalajara, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by inflammation of the synovial membrane of the diarthrodial joints which include arthrodesis of the middle ear, (incudomalleolar and…
  • Abstract Number: 2128 • 2015 ACR/ARHP Annual Meeting

    The Role of Insulin Resistance in the Development of Premature Atherosclerosis in Patients with Rheumatoid Arthritis

    Gorica Ristic1, Vesna Subota2, Toplica Lepic3, Dejana Stanisavljevic4, Branislava Glisic1, Milan Petronijevic1, Arsen Ristic5 and Dusan Stefanovic1, 1Department of Rheumatology and Clinical Immunology, Military Medical Academy, Belgrade, Serbia, 2Institute of Medical Biochemistry, Military Medical Academy, Belgrade, Serbia, 3Department of Neurology, Military Medical Academy, Belgrade, Serbia, 4Institute of Medical Statistics, Belgrade University School of Medicine, Belgrade, Serbia, 5Department of Cardiology, Clinical Center of Serbia & Belgrade University School of Medicine, Belgrade, Serbia

    Background/Purpose: Accelerated atherosclerosis in rheumatoid arthritis (RA) is well established but the role of insulin resistance in RA pts without diabetes or metabolic syndrome remains…
  • Abstract Number: 1548 • 2015 ACR/ARHP Annual Meeting

    Comparison of 5 Cardiovascular Risk Calculators in a Hispanic Rheumatoid Arthritis Cohort

    Alberto Cardenas-de La Garza1, Raymundo Vera-Pineda2, Dionicio A. Galarza-Delgado1, Jose Ramon Azpiri-Lopez3, Iris J. Colunga-Pedraza1, Griselda Serna-Peña4 and Mario Alberto Garza-Elizondo1, 1Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 2Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, 3Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, 4Internal Medicine, Hospital Universitario, UANL., Monterrey, Mexico

    Background/Purpose: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in RA. Management and stratification of ASCVD in RA patients is still a matter…
  • Abstract Number: 2343 • 2015 ACR/ARHP Annual Meeting

    Impact of Colchicine Use on the Development of Incident Coronary Artery Disease

    Susanna Jeurling1, Daria Crittenden2, Mark C. Fisher3, Binita Shah4, Steven P. Sedlis4, Craig T. Tenner5, Svetlana Krasnokutsky Samuels6 and Michael H. Pillinger7, 1Division of Rheumatology, NYU School of Medicine, New York, NY, 2Rheumatology, NYU-HJD, New York, NY, 3Rheumatology, New York Univ-HJD, New York, NY, 4NYU School of Medicine, Division of Cardiology, New York, NY, 5Medicine, NYU School of Medicine, New York, NY, 6NYU School of Medicine, Division of Rheumatology, New York, NY, 7Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY

    Background/Purpose: Patients with gout experience both inflammation and increased risk of cardiovascular disease (CVD). Studies suggest that colchicine reduces myocardial infarction (MI) risk, but whether…
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