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Abstracts tagged "anti-CCP antibodies"

  • Abstract Number: 1691 • 2012 ACR/ARHP Annual Meeting

    Early Signs of Subclinical Inflammation and Local Antibody Production in Early Rheumatoid Lungs

    Gudrun Reynisdottir1, Reza Karimi2, Jimmy Ytterberg3, Vijay Joshua1, Helga Olsen2, Aase Haj Hensvold1, Anders Harju4, Johan Grunewald2, Sven Nyren5, Anders Eklund2, Lars Klareskog6, Roman Zubarev7, Magnus Skold2 and Anca Catrina1, 1Department of Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 2Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 3Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 4Department of Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 5Radiology, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, 6Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden, 7Karolinska Institutet, Stockholm, Sweden

    Background/Purpose:  The aims of the current study was to investigate if inflammatory lung changes are present in RA patients early in the disease process and…
  • Abstract Number: 31 • 2012 ACR/ARHP Annual Meeting

    Anti Citrullinated Protein Antibodies From Synovial Fluid of Rheumatoid Arthritis Patients Enhance Osteoclastogenesis

    Akilan Krishnamurthy1, Nancy Vivar Pomiano2, Catia Cerqueira3, Elena Ossipova3, Karin Lundberg4, Ulrike Harre5, Vivianne Malmström6, Per Johan Jakobsson7, Lars Klareskog8, Georg Schett9 and Anca Catrina3, 1Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 2Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 3Department of Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 4Rheumatology unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 5Institute for Clinical Immunology, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 6Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 7Rheumatology unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 8Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden, 9Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose: Presence of anti CCP2 antibodies identifies a subgroup of RA patients that are more prone to develop bone erosions. We hypothesized that anti CCP2…
  • Abstract Number: 1615 • 2012 ACR/ARHP Annual Meeting

    Evidence for Distinct Roles of Environmental and Genetic Factors in the Emergence of Anti Citrullinated-Protein Antibodies Positive Rheumatoid Arthritis-an Epidemiological Investigation in Twins

    Aase Haj Hensvold1, Patrik KE Magnusson2, Monika Hansson3, Lena Israelsson4, Cecilia Carlens1, Johan Askling5, Vivianne Malmström6, Lars Klareskog7 and Anca Catrina1, 1Department of Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 2Medical Epidemiology and Biostatistics, Swedish Twin Registry Karolinska Institutet, Stockholm, Sweden, 3Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 4Department of Medicine, Karolinska Institute, Stockholm, Sweden, 5Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 6Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 7Department of Medicine, Rheumatology Unit, Karolinska Institute, Stockholm, Sweden

    Background/Purpose:  The aim of the current study was to investigate the influence of genetic and environmental factors in developing anti citrullianted-proteins antibodies (ACPA) and ACPA…
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