Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 1480 • ACR Convergence 2024
Sustained Improvements with Bimekizumab in Spinal Mobility, Physical Function and Health-Related Quality of Life in Patients with Axial Spondyloarthritis: 2-Year Results from Two Phase 3 Studies
Victoria Navarro Compán¹, Maureen Dubreuil², Karl Gaffney³, Jonathan Kay⁴, Christine de la Loge⁵, Ute Massow⁶, Vanessa Taieb⁷, Thomas Vaux⁸ and Atul Deodhar⁹, ¹La Paz University Hospital, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain, ²Section of Rheumatology, Boston University School of Medicine, Boston, MA, ³Health Care - NHS, Norwich, United Kingdom, ⁴Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA, ⁵UCB Pharma, Brussels, Belgium, ⁶UCB Pharma, Monheim am Rhein, Germany, ⁷UCB Pharma, Colombes, France, ⁸UCB Pharma, Slough, United Kingdom, ⁹Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR
Background/Purpose: In the phase 3 BE MOBILE 1 and 2 studies, bimekizumab (BKZ), a monoclonal IgG1 antibody that inhibits interleukin (IL)-17F in addition to IL-17A,…
Abstract Number: 2278 • ACR Convergence 2024
Similar Etanercept Adherence in Individuals with Rheumatic Disease Initiating Originator and Biosimilar: A Population-Based Study
Olga Tsyruk¹, Marina Birck², Sasha Bernatsky², Luck Lukusa³, Denis Choquette⁴, Gilles Boire⁵ and Walter Maksymowych⁶, ¹McGill University, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁴Rhumadata™, Montreal, QC, Canada, ⁵Retired, Sherbrooke, QC, Canada, ⁶University of Alberta, Edmonton, AB, Canada
Background/Purpose: Treatment adherence is crucial to optimizing outcomes in rheumatic diseases. Suboptimal adherence is common with inflammatory and chronic diseases, often treated with biologics, including…
Abstract Number: L11 • ACR Convergence 2023
Risk of Cardiovascular Events According to Biological Agent Exposure in Patients with Ankylosing Spondylitis: A Korean Population-based Study
Oh Chan Kwon, Hye Sun Lee, Juyeon Yang, Yong-Beom Park and Min-Chan Park, Yonsei University College of Medicine, Seoul, South Korea
Background/Purpose: Patients with ankylosing spondylitis (AS) have a higher risk of cardiovascular events than controls. Although biological disease-modifying anti-rheumatic drugs (bDMARDs) are efficacious in treating…
Abstract Number: 0326 • ACR Convergence 2023
Assessment of Depression in Ankylosing Spondylitis Using Center for Epidemiologic Studies Depression Scale
Yvette Farran¹, Mark Hwang¹, John Reveille², Lianne Gensler³, Accelerating Medicines Partnership Program RA SLE Network⁴, Mariko Ishimori⁴ and Michael Ward⁵, ¹The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, ²The University of Texas Health Science Center, Houston, TX, ³University of California San Francisco, Department of Medicine, Division of Rheumatology, San Francisco, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD
Background/Purpose: Ankylosing Spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine and sacroiliac joints. Depression is a common comorbidity in AS patients…
Abstract Number: 0536 • ACR Convergence 2023
Asynchronous Tele Consultation by WhatsApp Chatbot in Controlled Axial Spondyloartrhitis Patients Under Biological Therapy: Patients Perspective
Maria Luz Garcia Vivar¹, elena abad plou², Natalia Rivera³, Eva Galindez-Agirregoikoa¹, Eduardo Cuende⁴, Ana Rosa Intxaurbe⁵, Juan M Blanco Madrigal¹, Lucia Vega-Alvarez¹, Carmen Lucia Garcia-Gomez⁶, Maria Enjuanes-Noguero⁷, Olaia Fernandez-Berrizbeitia⁸, Maria Rosa Exposito Molinero⁹, Maria Esther Ruiz Lucea¹, Ignacio Torre Salaberri⁵ and iñigo Gorostiza Hormaeche¹, ¹Basurto University Hospital, Bilbao, Spain, ²Hospital universitario de Basurto, Bilbo, Spain, ³Biocruces Bizkaia Health Research Institute, Research area, Bilbao, Spain, ⁴Basurto University Hospital, Rheumatology, Madrid, Spain, ⁵Basurto University Hospital, Rheumatology, Bilbao, Spain, ⁶Basurto University Hospital, Rheumatology, Terrassa, Spain, ⁷Hospital Universitario de Basurto, Bilbao, Spain, ⁸Spanish Health Care Service, Bilbao, Spain, ⁹Hospital de Basurto, Bilbao, Spain
Background/Purpose: Before COVID pandemic, rheumatologists were not confident with telehealth for the need to adquire new technology, need of specific training and poorer reimbursement (1).…
Abstract Number: 1391 • ACR Convergence 2023
Rates of Remission in Patients with Axial Spondyloarthritis Treated in Tertiary Care
Franziska Neinert¹, Imke Redeker², Styliani Tsiami¹, David Kiefer¹, Barbara Guminski¹, Xenofon Baraliakos³, Juergen Braun¹ and Uta Kiltz⁴, ¹Ruhr-Universität Bochum and Rheumazentrum Ruhrgebiet, Herne, Germany, ²Ruhr Universität Bochum, Bochum, Germany, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Achieving remission is the treatment target for patients (pts.) with axial spondyloarthritis (axSpA).Remission rates over longer periods in a real-life setting have not been…
Abstract Number: 1411 • ACR Convergence 2023
Prevalence of Early Axial Spondyloarthritis in the Be-GIANT Cohort Based on the ASAS Consensus Definition of Early Axial Spondyloarthritis
Gaelle Varkas¹, Ann-Sophie De Craemer², Zuzanna Lukasik¹, Thomas Renson³, Liselotte Deroo⁴, Philippe Carron⁵, Dirk Elewaut⁶ and Filip Van den Bosch⁷, ¹Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium, ²Ghent University Hospital, Gent, Belgium, ³Dept. of Pediatrics, Ghent University Hospital, Ghent, Belgium, ⁴Ghent University, Gent, Belgium, ⁵UZ Gent, Gent, Belgium, ⁶Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, ⁷Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Ghent, Belgium
Background/Purpose: Recently, the Assessment of SpondyloArthritis international Society (ASAS) community, led by the ASAS-SPEAR (SPondyloarthritis EARly definition) working group, endorsed a uniform definition for early…
Abstract Number: 2439 • ACR Convergence 2023
Proteomic and Genomic Profiling of Plasma Exosomes from Ankylosing Spondylitis Patients
Fataneh Tavasolian¹, starlee lively², Chiara Pastrello³, Michael Tang², Melissa Lim², Addison Pacheco², Zoya Qaiyum², Enoch Yau², Zeynep Baskurt⁴, Igor Jurisica⁵, Mohit Kapoor⁶ and Robert Inman², ¹Krembil Research Institute, University Health Network, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Osteoarthritis Research Program, Division of Orthopaedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic diseases, Krembil Research Institute, Toronto, ON, Canada, ⁴Department of Biostatistics, University Health Network, Toronto, ON, Canada, ⁵Schroeder Arthritis Institute, Krembil Research Institute and Departments of Medical Biophysics and Computer Science and Faculty of Dentistry, University of Toronto and Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia, ⁶Division of Orthopaedics, Osteoarthritis Research Program, Schroeder Arthritis Institute, and Krembil Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Recent advances in understanding the biology of Ankylosing Spondylitis (AS) using innovative genomic and proteomic approaches offer the opportunity to address current challenges in…
Abstract Number: 0327 • ACR Convergence 2023
Self-management Strategies and Self-efficacy in Patients Living with Inflammatory Arthritis: Findings from a Quality Improvement Project in a Tertiary Centre
Saadia Sasha Ali¹, Karafotias Ioasaf², Bechman Katie³, Andrew Rutherford⁴, Sophia Steer³ and Elena Nikiphorou³, ¹King's College Hospital, Epsom, United Kingdom, ²King's College Hospital, London, United Kingdom, ³King's College London, London, United Kingdom, ⁴King's College Hospital, London, United Kingdom
Background/Purpose: The 2021 EULAR guidelines on self-management have made recommendations (rec) to aid with the implementation of self-management strategies in inflammatory arthritis (IA) (1). Their…
Abstract Number: 0537 • ACR Convergence 2023
Asynchronous Teleconsultation by WhatsApp Chatbot in Controlled Axial Spondyloartrhitis Patients Under Biological Therapy as a More Sustainable Model Than Face-to-face Classical Consultation
Natalia Rivera¹, elena abad plou², Eva Galindez-Agirregoikoa³, Eduardo Cuende⁴, Ana Rosa Intxaurbe⁵, Juan M Blanco Madrigal³, Lucia Vega-Alvarez³, Carmen Lucia Garcia-Gomez⁶, Maria Enjuanes-Noguero⁷, Olaia Fernandez-Berrizbeitia⁸, Maria Rosa Exposito Molinero⁹, Maria Esther Ruiz Lucea³, Ignacio Torre Salaberri⁵, iñigo Gorostiza Hormaeche³ and Maria Luz Garcia Vivar³, ¹Biocruces Bizkaia Health Research Institute, Research area, Bilbao, Spain, ²Hospital universitario de Basurto, Bilbo, Spain, ³Basurto University Hospital, Bilbao, Spain, ⁴Basurto University Hospital, Rheumatology, Madrid, Spain, ⁵Basurto University Hospital, Rheumatology, Bilbao, Spain, ⁶Basurto University Hospital, Rheumatology, Terrassa, Spain, ⁷Hospital Universitario de Basurto, Bilbao, Spain, ⁸Spanish Health Care Service, Bilbao, Spain, ⁹Hospital de Basurto, Bilbao, Spain
Background/Purpose: Before COVID pandemic, telehealth use for the followup of rheumatic disease patients had been limited, but nowadays it appears as a more sustainable model…
Abstract Number: 1392 • ACR Convergence 2023
Improving the Diagnostic Accuracy in Axial Spondyloarthritis: Interim Results of a Nationwide Telemedicine Project
Denis Poddubnyy¹, Marc Kämmerer², Marcus Kremers³, Berit Schoppen³, Charlotte Arens³, Annette Wiedon⁴, Imke Redeker⁵ and Xenofon Baraliakos⁶, ¹Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ²VISUS Health IT GmbH, Bochum, Germany, ³MedEcon Telemedizin GmbH / MedEcon Ruhr GmbH, Bochum, Germany, ⁴Novartis Pharma GmbH, Nürnberg, Germany, ⁵Ruhr Universität Bochum, Bochum, Germany, ⁶Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany
Background/Purpose: Axial spondyloarthritis (axSpA) is often diagnosed late, while there is also a problem of over- and misdiagnosis in patients with chronic back pain. Imaging,…
Abstract Number: 1726 • ACR Convergence 2023
Therapeutic Effect of ICAM-1 Mimic on Experimental Axial Spondyloarthritis
Melissa Lim¹, Shaghayegh Foroozan², Zoya Qaiyum³, Michael Tang¹, Enoch Yau⁴ and Robert Inman¹, ¹University Health Network, Toronto, ON, Canada, ²University Health Network/University of Toronto, Toronto, ON, Canada, ³Krembil Research Institute, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada
Background/Purpose: Axial Spondyloarthritis (AxSpA) is a chronic inflammatory arthritis primarily affecting the axial skeleton and commonly coexists with gut and skin inflammation. Currently, patients with…
Abstract Number: 2442 • ACR Convergence 2023
Neutrophils Induce Contact-Dependent Expansion of Arthritogenic Th17 Cells and Are Necessary for Disease in Experimental Ankylosing Spondylitis
Hillary Struthers¹, Emily Vance¹, Kofi Asare-Konadu¹, Holly Rosenzweig² and Ruth Napier¹, ¹Oregon Health & Science University, Portland, OR, ²VA Portland Healthcare System, Portland, OR
Background/Purpose: Ankylosing spondylitis (AS) patients have irregular neutrophil responses, as indicated clinically by neutrophilia and increased neutrophil to lymphocyte ratios that positively associate with disease…
Abstract Number: 0333 • ACR Convergence 2023
Ankylosing Spondylitis Patient Perspective on Living with Flares and Impact on Quality of Life
Heather Lapidus Glassner and Elizabeth Luce, MyHealthTeam, San Francisco, CA
Background/Purpose: Ankylosing spondylitis (AS) leads to symptoms of pain, stiffness, swelling, and fatigue. Patients often report periods of increased symptoms (flares) followed by remission.The purpose…
Abstract Number: 0539 • ACR Convergence 2023
Impact of Extreme Baseline BASDAI and/or Maastricht AS Enthesitis Score on Treatment Response to Upadacitinib in Patients with Axial Spondyloarthritis
Maxime Dougados¹, David Bulbin², Heather Jones³, Tianming Gao⁴, Anna Shmagel⁵, Thomas Poznanski⁶, Abhijeet Danve⁷ and Karl Gaffney⁸, ¹Université de Paris, Paris, France, ²Geisinger Health System, Danville, PA, ³AbbVie, Inc., Mettawa, IL, ⁴AbbVie, Inc., North Chicago, IL, ⁵AbbVie, Inc., Long Grove, IL, ⁶AbbVie, Inc., Plainfield, IL, ⁷Yale University, New Haven, CT, ⁸Norfolk and Norwich University Hospital NHS Trust, Norfolk, United Kingdom
Background/Purpose: Axial SpA (axSpA) and FM manifest with overlapping clinical features such as pain, fatigue, and stiffness, yet their treatment is distinctly different. FM is…

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