Abstract Number: 42 • 2014 ACR/ARHP Annual Meeting
The Prevalence of Ankylosing Spondylitis in Sweden – a Nationwide Register Study
Background/Purpose: Reported Ankylosing Spondylitis (AS) prevalence estimates vary considerably, and there is a lack of nationwide estimates. Previous studies by our group support the validity…Abstract Number: 2612 • 2014 ACR/ARHP Annual Meeting
Different Performance of the Major Disease Activity Measures ASDAS and Basdai in Patients with Axial Spondyloarthritis Treated with Non-Steroidal Anti-Inflammatory Agents – Results from a Prospective Study
Background/Purpose: The ASAS/EULAR recommendations for the management of patients (pts) with axial spondyloarthritis (axSpA) have established non-steroidal anti-inflammatory agents (NSAIDs) as first choice of medical…Abstract Number: 2150 • 2014 ACR/ARHP Annual Meeting
The Craniocervical Junction in Ankylosing Spondylitis: A Computed Tomography Based Study
Background/Purpose Available studies of craniocervical junction (CCJ) involvement in ankylosing spondylitis (AS) are based on conventional radiography, which has limited ability in the definition of…Abstract Number: 613 • 2014 ACR/ARHP Annual Meeting
The Amount of Free Heavy Chain and β2-Microglobulin in the Cytoplasm of B*2705 Ankylosing Spondylitis Patients Compared to B*2705 and B*2709 Healthy Subjects Does Not Support the UPR Theory. Influence of ERAP1 Polymorphisms
Background/Purpose : Ankylosing Spondylitis (AS) is a chronic inflammatory disease of the spine strongly associated with the majority of HLA-B27 alleles, with the exception of…Abstract Number: 563 • 2014 ACR/ARHP Annual Meeting
Evaluation of Clinical Parameters and Quality of Life in Smokers with Ankylosing Spondylitis: Results from the Scotland Registry for Ankylosing Spondylitis
Background/Purpose: Several studies have shown that smoking is associated with increased disease activity, worse physical function and poor quality of life in ankylosing spondylitis (AS). …Abstract Number: L21 • 2014 ACR/ARHP Annual Meeting
Striking Discrepancy in the Development of Anti-Drug Antibodies (ADA) in Patients with Rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS) in Response to Infliximab (INF) and Its Biosimilar CT-P13
Background/Purpose: The differences between RA and AS have been recently highlighted (1). There is evidence that there are major clinical, pathophysiological and genetic differences. In…Abstract Number: 2610 • 2014 ACR/ARHP Annual Meeting
The Role of IL-20 in the Pathogenesis of Ankylosing Spondylitis with Peripheral Joint Involvement
Background/Purpose The interleukin-20 (IL-20) is a pro-inflammatory cytokine of the IL-10 family and sequence amino acid is very similar. It has been reported to be…Abstract Number: 2149 • 2014 ACR/ARHP Annual Meeting
Relationship Between the Magnitude of Bone Formation in the Anterior Vertebral Corners, As Assessed through 18F-Fluoride Uptake, and Lumbar Spine Bone Mineral Density in Patients with Ankylosing Spondylitis
Background/Purpose: 18F-fluoride uptake represents active osteoblastic bone synthesis. We investigated the relationship between the magnitude of bone formation in anterior vertebral corners, as assessed through…Abstract Number: 612 • 2014 ACR/ARHP Annual Meeting
Association of Platelet Endothelial Cell Adhesion Molecule-1 and beta1 Integrin Gene Polymorphisms with Uveitis Development in Ankylosing Spondylitis
Background/Purpose Genetic factors provide over 90% of the overall susceptibility to ankylosing spondylitis (AS) and recent studies have focused on non-major histocompatibility complex genes. The…Abstract Number: 578 • 2014 ACR/ARHP Annual Meeting
Female Patients but Not Male Patients with Ankylosing Spondylitis Are at Increased Risk of Developing Ischemic Heart Disease: A Population-Based Cohort Study
Background/Purpose: It is well recognized that rheumatoid arthritis is an independent risk factor for cardiovascular disease. For ankylosing spondylitis (AS), the literature on this risk…Abstract Number: 2607 • 2014 ACR/ARHP Annual Meeting
Fatigue in Ankylosing Spondylitis: A Multivariable Analysis Implicates Inflammation As the Key Determinant of Disability
Background/Purpose: Fatigue is one of the cardinal features of ankylosing spondylitis (AS). The clinical and laboratory correlates of fatigue in AS however are not well…Abstract Number: 1919 • 2014 ACR/ARHP Annual Meeting
HLA-B27 Expression Shapes the Intestinal Microbiota
Background/Purpose The intestinal microbiota plays a central role in both health and disease. Beyond shaping local immune responses in the gut, it is increasingly clear…Abstract Number: 608 • 2014 ACR/ARHP Annual Meeting
Identification of Novel Autoantibodies in Patients with Ankylosing Spondylitis Using Human Protein Microarray
Background/Purpose: Ankylosing spondylitis (AS) is an immune-mediated disease for which the search for autoantibodies has been elusive. Conventional immunoserological approaches are slow and limited…Abstract Number: 574 • 2014 ACR/ARHP Annual Meeting
Do Extra-Articular Manifestations Influence Outcome in Ankylosing Spondylitis? a 12 Year Follow-up Study
Background/Purpose: Extra-articular manifestations (EAMs), such as acute anterior uveitis (AAU), inflammatory bowel disease (IBD), and psoriasis contribute to diagnosis, classification criteria, and choice of treatment…Abstract Number: 2985 • 2014 ACR/ARHP Annual Meeting
Autoantibodies to 14-3-3η Are Novel Biomarkers Associated with Inflammation and Radiographic Progression in Ankylosing Spondylitis
Background/Purpose 14-3-3η is a ubiquitous intracellular chaperone protein that is expressed extracellularly in rheumatoid arthritis and mediates inflammatory cascades that result in expression of inflammatory…
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