Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 2885 • 2013 ACR/ARHP Annual Meeting
Erosions and Sclerosis, But Not Squaring, Predict The Development Of New Syndesmophytes: A 12-Year Longitudinal Analysis (OASIS)
Sofia Ramiro¹, A.M. van Tubergen², Désirée van der Heijde³, Carmen Stolwijk⁴, Maxime Dougados⁵, Filip Van den Bosch⁶ and Robert Landewé⁷, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands
Background/Purpose: Erosions, sclerosis and squaring are included in the modified Stoke Ankylosing Spondylitis (AS) Spine Score (mSASSS). However, their value in predicting the development of…
Abstract Number: 2453 • 2013 ACR/ARHP Annual Meeting
Identification Of Determinants Of The Functional Outcome In Patients With Early Axial Spondyloarthritis: Results From The German Spondyloarthritis Inception Cohort
Denis Poddubnyy¹, Hildrun Haibel¹, Joachim Listing², Jürgen Braun³, Martin Rudwaleit⁴ and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Center, Berlin, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Endokrinologikum, Berlin, Germany
Background/Purpose: In cross-sectional studies it has been shown already that functional status in ankylosing spondylitis (AS), which represents probably the most important long-term outcome in…
Abstract Number: 2107 • 2013 ACR/ARHP Annual Meeting
Benefitial Effects Of a Simple Stretching Exercise Program For Patients With Ankylosing Spondylitis: A Randomized Controlled Trial
Andréa L. Gallinaro¹, Carla G.S. Saad¹, Claudia Goldenstein-Schainberg¹, Percival D sampaio-Barros¹, Julio C. B. Moraes¹, Hamilton Roschel², Ana Lucia S. Pinto¹ and Celio R. Gonçalves³, ¹Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, ²Universidade de São Paulo, Faculdade de Educação Física e Esporte, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Static and dynamic stretching exercises are applied in Ankylosing Spondylitis (AS) patients to preserve and restore the axial mobility. However, there are no data…
Abstract Number: 1523 • 2013 ACR/ARHP Annual Meeting
Presence Of Peripheral Arthritis Delays Spinal Radiographic Progression In Ankylosing Spondylitis: Observation Study Of Korean Spondyloarthropathy Registry (OSKAR) Over 5 Years
Tae-Jong Kim¹, Seunghun Lee², Kyung-Bin Joo³, Dong-Jin Park⁴, Yong-Wook Park⁴, Shin-Seok Lee⁵ and Tae-Hwan Kim⁶, ¹Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ⁵Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ⁶Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: The most unique feature in ankylosing spondylitis (AS) is subchondral eburnation and syndesmophytes, possibly leading to ankylosis and spinal fusion. So far a clear…
Abstract Number: 1117 • 2013 ACR/ARHP Annual Meeting
Integrated ¹⁸f-Fluoride Positron Emission Tomography and Magnetic Resonance Imaging Of The Spine – a Pilot Study and Comparison Of Signals In Patients With Axial Spondyloarthritis
Xenofon Baraliakos¹, Dr. Christian Buchbender², Ben Ostendorf³, Verena Hartung, MD⁴, Thorsten Poeppel, MD⁴ and Juergen Braun⁵, ¹Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ²Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, ³Rheumatology, Heinrich-Heine-University, Duesseldorf, GA, Germany, ⁴Dept. Nuclear Medicine, University Duisburg-Essen, Duisburg, Germany, ⁵Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Positron emission tomography (PET) is a high sensitive nuclear imaging technique that depicts functional processes within the body. PET scanners detect annihilation radiation from…
Abstract Number: 107 • 2013 ACR/ARHP Annual Meeting
Duration Of Symptoms Before Diagnosis In Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
Merete Lund Hetland^1,2 and Jan Sørensen³, ¹The Danish Rheumatologic Database (DANBIO), Glostrup Hospital, Glostrup, Denmark, ²Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, The Danish Rheumatologic Database (DANBIO), Glostrup Hospital., Copenhagen, Denmark, ³Center for Applied Health Services Research, University of South Denmark, Odensen, Denmark
Background/Purpose: Early diagnosis is important for the treatment of many rheumatic diseases. Little is known about the duration of symptoms before establishment of diagnosis, and if the…
Abstract Number: 2887 • 2013 ACR/ARHP Annual Meeting
The Spondyloarthritis Research Consortium Of Canada MRI Sacroiliac Joint Structural Score: A Method For Reliable Detection Of Structural Progression
Walter P. Maksymowych¹, Stephanie Wichuk¹, Praveena Chiowchanwisawakit², Robert GW Lambert³ and Susanne Juhl Pedersen⁴, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Mahidol University, Bangkok, Thailand, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark
Background/Purpose: With increasing focus on effective treatment intervention in early spondyloarthritis, there is an unmet need for reliable assessment of structural progression in the…
Abstract Number: 2455 • 2013 ACR/ARHP Annual Meeting
The Lipid Profile Improves In Patients With Ankylosing Spondylitis Responding To TNF Blocking Therapy
Sjoerd C. Heslinga^1,2, Irene E. Van der Horst-Bruinsma^3,4, Alper M. van Sijl^2,3 and Michael T Nurmohamed^1,5, ¹Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ²Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ³Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁴Department of Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ⁵VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Patients with ankylosing spondylitis (AS) have a decreased life expectancy due to an increased cardiovascular risk. Cardiovascular risk factors such as smoking, dyslipidemia, overweight,…
Abstract Number: 2041 • 2013 ACR/ARHP Annual Meeting
Pregnancy Outcomes In Women Exposed To Golimumab
Amy G. Lau¹, Michael Clark¹, Diane D. Harrison¹, Anja Geldhof², Riikka Nissinen² and Marilyn Sanders¹, ¹Janssen Research & Development, LLC., Horsham, PA, ²Janssen Biologics Europe, Leiden, Netherlands
Background/Purpose: Rheumatologic conditions and inflammatory bowel disease can affect women of childbearing potential. Golimumab (GLM) is approved for rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing…
Abstract Number: 1525 • 2013 ACR/ARHP Annual Meeting
Measurement Of Lateral Spinal Flexion and Schober Is Sufficient To Be Informed About Spinal Mobility In Patients With Ankylosing Spondylitis: 12-Year OASIS Results
Sofia Ramiro¹, Robert Landewé², Désirée van der Heijde³, Carmen Stolwijk⁴, Maxime Dougados⁵, Filip Van den Bosch⁶ and A.M. van Tubergen⁷, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: We have shown that spinal mobility gets impaired in a fixed order in ankylosing spondylitis (AS), with the highest impairment in lumbar spine. We…
Abstract Number: 1118 • 2013 ACR/ARHP Annual Meeting
Assessment Of Structural Damage In Patients With Ankylosing Spondylitis Using 18F-Fluoride Positron Emission Tomography-Magnetic Resonance Imaging
GeunTae Kim¹, Seung-Geun Lee², Seong-Ho Kim³, Joung-Wook Lee⁴ and Seung-Hoon Baek⁵, ¹Kosin University College of Medicine, Busan, South Korea, ²Divsion of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea, ³Internal Medicine, Division of Rheumatology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea, ⁴Divsion of Rheumatology, Department of Internal Medicine, Busan St. Mary’s Medical Center, Busan, South Korea, ⁵Divsion of Rheumatology, Department of Internal Medicine, Ilsin Christian Hospital, Busan, South Korea
Background/Purpose: 18F-fluoride uptake represents active osteoblastic bone synthesis. We explored structural damage of patients with ankylosing spondylitis (AS) using 18F-fluoride positron emission tomography (PET)-magnetic resonance…
Abstract Number: L15 • 2013 ACR/ARHP Annual Meeting
Efficacy and Safety of CT-P13 (Infliximab Biosimilar) over Two Years in Patients with Ankylosing Spondylitis: Comparison Between Continuing with CT-P13 and Switching from Infliximab to CT-P13
Won Park¹, Pedro Miranda², Marek Brzosko³, Piotr Wiland⁴, Sergio Gutierrez-Ureña⁵, Helena Mikazane⁶, Yeon-Ah Lee⁷, Svitlana Smiyan⁸, Mie-Jin Lim¹, Vladimir Kadinov⁹, Carlos Abud-Mendoza¹⁰, YoungKi Son¹¹, Dae-Hyun Yoo¹² and Jürgen Braun¹³, ¹Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, South Korea, ²Universidad de Chile and Centro de Estudios Reumatologicos, Santiago de Chile, Chile, ³Department of Rheumatology and Internal Diseases, Department of Rheumatology and Internal Diseases Pomeranian Medical University in Szczecin, Szczecin, Poland, ⁴Department of Rheumatology, Medical University of Wroclaw, Wroclaw, Poland, ⁵Antiguo Hospital Civil de Guadalajara, Guadalajara, Mexico, ⁶Outpatient Clinic 'ORTO', Riga, Latvia, ⁷Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ⁸Municipal Institution of Ternopil Regional Council "Ternopil University Hospital", Ternopil, Ukraine, ⁹Multiprofile Hospital for Active Treatment 'Sv. Marina', Varna, Bulgaria, ¹⁰Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosyi, Mexico, ¹¹CELLTRION, Incheon, South Korea, ¹²Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ¹³PsAID taskforce, EULAR, Zurich, Switzerland
Background/Purpose: CT-P13 is an infliximab (INX) biosimilar recently approved by the European Medicine Agency. PLANETAS was a 54-week (wk) randomized double-blind parallel group multicenter Phase…
Abstract Number: 2888 • 2013 ACR/ARHP Annual Meeting
Frequent Detection Of Inflammation and Fat Infiltration Suggestive Of Spondyloarthritis On MRI Of The Entire Spine In Healthy Subjects and Patients With Mechanical Back Pain
Ulrich Weber¹, Zheng Zhao², Veronika Zubler³, Stanley Chan⁴, Robert GW Lambert⁵, Mikkel Ostergaard⁶, Susanne Juhl Pedersen⁷, Kaspar Rufibach⁸ and Walter P. Maksymowych⁹, ¹Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ²Department of Rheumatology, University of Alberta and PLA General Hospital, Beijing, PR China, Beijing, AB, China, ³Radiology, Balgrist University Hospital, Zurich, Switzerland, ⁴Division of Ophthalmology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Copenhagen Center for Arthritis Research, Glostrup, Denmark, ⁷Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ⁸rePROstat, Basel, Switzerland, ⁹Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Mechanical back pain (MBP) patients and healthy subjects may show spinal MRI lesions suggestive for spondyloarthritis (SpA) such as corner inflammatory lesions (CIL) or…
Abstract Number: 2456 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Overweight and Obesity and The Relation To Disease Activity, Physical Function and Quality Of Life In Patients With Axial Spondyloarthritis
Fiona Maas¹, Anneke Spoorenberg¹, Eveline van der Veer², Reinhard Bos³, Monique Efde³, Hendrika Bootsma⁴, Elisabeth Brouwer⁵ and Suzanne Arends^3,4, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ²Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, ⁴Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ⁵Dept. of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Obesity is a growing problem in Western society. It is associated with an increased risk for many disorders, impaired functional capacity, and impaired quality…
Abstract Number: 2042 • 2013 ACR/ARHP Annual Meeting
Pregnancy Outcomes In Women With Rheumatologic Conditions Exposed To Infliximab
Sirisha Kalari¹, Fredrik Granath², Chun-Yuan Guo¹, Diane D. Harrison¹, Gabriella Bröms², Anja Geldhof³, Riikka Nissinen³, Marilyn Sanders¹, Mika Gissler⁴, Lars Pedersen⁵, Henrik Toft Sorensen⁵ and Helle Kieler², ¹Janssen Research & Development, LLC., Horsham, PA, ²Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden, ³Janssen Biologics Europe, Leiden, Netherlands, ⁴Information Department, National Institute for Health and Welfare, Helsinki, Finland, ⁵Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: RA, AS, and PsA are approved indications for infliximab (IFX). In the US, IFX is a pregnancy Category B drug. For RA and some…

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