Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 1506 • 2013 ACR/ARHP Annual Meeting
Total Hip Replacement Outcomes in Ankylosing Spondylitis
Susan M. Goodman¹, Rebecca Zhu², Wei-Ti Huang³, Mark P. Figgie⁴, Michael Alexiades⁵ and Lisa A. Mandl¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Clinical Research, Hospital for Special Surgery, New York, NY, ³Epidemiology and Statistics, Hospital for Special Surgery, New York, NY, ⁴Orthopedics, Hospital for Special Surgery, New York, NY, ⁵Orthopaedics, Hospital for Special Surgery, New York, NY
Background/Purpose: Historically, outcomes for total hip replacement (THR) in ankylosing spondylitis (AS) patients were poor, but contemporary outcomes are not well described. We analyzed two-year…
Abstract Number: 991 • 2013 ACR/ARHP Annual Meeting
Utilization Of An Informational Needs Assessment To Develop An Education Program For Patients With Ankylosing Spondylitis (AS) and Related Axial Spondyloarthritis (SpA)
Rita Kang¹, Rebecca Morton², Christopher Hawke³, Laura A. Passalent⁴, Robert D. Inman^5,6, Dinny Wallis⁷, Joan Blair³, Alison Lake⁸, Heather Sloman⁸, Marc Doucet⁹, Debra MacGarvie⁸ and King Wong⁹, ¹Patient Education, University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ²Allied Health/Rheumatology, University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ³Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁴Allied Health, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁵Dept of Medicine/Rheumatology, Toronto Western Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, ⁶U of Toronto, Toronto, ON, Canada, ⁷Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁸University Health Network- Toronto Western Hospital, Toronto, ON, Canada, ⁹University Health Network, Toronto, ON, Canada
Background/Purpose: The effectiveness of education programs for patients with arthritis has been well documented. Despite this, there has been minimal investigation into patient education specifically…
Abstract Number: 2697 • 2013 ACR/ARHP Annual Meeting
Identification Of Genetic and Epigenetic Alterations In Spondyloarthritis
Tibor A. Rauch¹, Beata Tryniszewska¹, Andras Vida¹, Timea Ocsko¹, Sandor Szanto², Holly L. Rosenzweig³, Matthew A. Brown⁴, Gethin P Thomas⁵, Katalin Mikecz¹ and Tibor T. Glant¹, ¹Orthopedic Surgery, Rush University Medical Center, Chicago, IL, ²Rheumatology, University of Debrecen, Debrecen, Hungary, ³Oregon Health & Science University, Portland, OR, ⁴Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁵Translational Reserch Institute, University of Queensland Diamantina Institute, Woolloongabba, Australia
Background/Purpose: Ankylosing spondylitis (AS) is the prototypic spondyloarthritis and affects approximately 0.2-0.5% of the human population. It is estimated that genetic risk factors contribute >90%…
Abstract Number: 2440 • 2013 ACR/ARHP Annual Meeting
Is There a Role For Etoricoxib In Patients With Axial Ankylosing spondylitis Refractory To Traditional NSAID?
Maria García Manrique¹, Pilar Font², Joan Calvet³, María Cruz Fernandez⁴, Carlos Montilla⁵, Luis Linares⁶, Elia Brito⁷, Xavier Juanola⁸, Juan Mulero⁹, Rubén Queiro¹⁰, Rosa M. Morla¹¹, Rosario Garcia-Vicuña¹², Alba Erra¹³, Mireia Moreno¹⁴, Marta Larrosa¹⁵, Eduardo Collantes¹⁶ and Jordi Gratacos¹⁷, ¹Rheumatology, Hospital Parc Taulí, Sabadell, Spain, ²Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ³Rheumatology, Corporació Sanitària Parc Taulí, Sabadell, Spain, ⁴Rheumatology, Hospital General de Móstoles, Mostoles, Spain, ⁵Rheumatology Service, Hospital Universitario de Salamanca, Salamanca, Spain, ⁶Rheumatology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, ⁷Rheumatology, Hospital Ramón y Cajal, Madrid, Spain, ⁸Rheumatology, University Hospital Bellvitge, Barcelona, Spain, ⁹Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Spain, ¹⁰Rheumatology Department. Hospital Universitario Central de Asturias, Oviedo, Spain, ¹¹Rheumatology, Hospital Sta Tecla, Tarragona, Spain, ¹²Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, ¹³Hospital de Sant Rafael, Barcelona, Spain, ¹⁴Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, ¹⁵Rheumatology, Hospital Universitari Parc Tauli, Sabadell, Spain, ¹⁶Rheumatology, Hospital Reina Sofia, Cordoba, Spain, ¹⁷Rheumatology Service, Hospital Universitari Parc Taulí, Sabadell (Barcelona), Spain
Background/Purpose: Anti-TNF treatment has demonstrated its effectiveness in axial ankylosing spondylitis (AS) patients with inadecuate response to traditional NSAIDs (tNSAIDs) therapy (>=2 tNSAIDs), but also aspects…
Abstract Number: 1706 • 2013 ACR/ARHP Annual Meeting
Fine-Mapping Major Histocompatibility Complex Variation Associated With Ankylosing Spondylitis Susceptibility
Adrian Cortes¹, International Genetics of Ankylosing Spondylitis Consortium (IGAS)², Paul de Bakker³ and Matthew A. Brown⁴, ¹Human Genetics Group, The University of Queensland Diamantina Insititute, Brisbane, Australia, ²University of Queensland Diamantina Institute, brisbane, Australia, ³Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands, ⁴University of Queensland Diamantina Institute, Brisbane, Australia
Background/Purpose: Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis. Thus far, 27 susceptibility loci have been identified in and outside the MHC in…
Abstract Number: 1508 • 2013 ACR/ARHP Annual Meeting
How Well Are The Assessment Of Spondyloarthritis International Society (ASAS) / Outcome Measures In Rheumatology (OMERACT) Core Outcome Sets For Ankylosing Spondylitis Implemented In Randomized Clinical Trials? A Systematic Literature Review
Wilson Bautista-Molano^1,2, Victoria Navarro-Compán¹, Robert Landewé³ and Désirée van der Heijde⁴, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, ³Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ⁴Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has selected a core set of variables to include as standardized endpoints in clinical trials and clinical…
Abstract Number: 530 • 2013 ACR/ARHP Annual Meeting
Pattern Recognition Receptor Stimulated Cytokine Expression By Spondyloarthritis Patient Macrophages
Yi-Ping Liu¹, Ashley Bomkamp², Jens Eickhoff³, Jack Schneck², Mike Khan⁴ and Judith Smith⁵, ¹Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, ²University of Wisconsin-Madison, Madison, WI, ³Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, ⁴Cellular and Molecular Pathology, University of Wisconsin-Madison, Madison, WI, ⁵Pediatrics, University of Wisconsin-Madison, Madison, WI
Background/Purpose: Spondyloarthritis (SpA) encompasses a group of chronic inflammatory conditions involving axial arthritis that includes ankylosing spondylitis (AS). GWAS studies in AS have implicated multiple…
Abstract Number: 2493 • 2013 ACR/ARHP Annual Meeting
Interleukin-17 Serum Levels Are Associated With Markers Of Systemic Inflammation In Patients With Active Ankylosing Spondylitis
Denis Poddubnyy¹, Alain Vicari², Hildrun Haibel¹, Jürgen Braun³, Martin Rudwaleit⁴ and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²EMD Serono, Geneva, Switzerland, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Endokrinologikum, Berlin, Germany
Background/Purpose: There is accumulating evidence that the Th17-signaling axis, particularly interleukin-17 (IL-17), plays an important role in the pathogenesis of ankylosing spondylitis (AS). Furthermore, biologics…
Abstract Number: 2444 • 2013 ACR/ARHP Annual Meeting
The Contribution Of Disease Activity On Function and Quality Of Life In Patients With Ankylosing Spondylitis; Investigating Causality By Using Structural Equation Model
Servet Akar¹, Sabri Erdem², Kivanc Akat³, Dilek Solmaz¹ and Ismail Sari¹, ¹Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, ²Business Administration, Dokuz Eylul University Faculty of Business, Izmir, Turkey, ³Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey
Background/Purpose: It has been demonstrated that patient reported questionnaires including disease activity, functional impairment, anxiety and depression were correlated each other. However the causal relationships…
Abstract Number: 1541 • 2013 ACR/ARHP Annual Meeting
Spinal Mobility Gets Impaired In a Fixed Order In Patients With Ankylosing Spondylitis: 12-Year OASIS Results
Sofia Ramiro¹, Robert Landewé², Désirée van der Heijde³, Carmen Stolwijk⁴, Maxime Dougados⁵, Filip Van den Bosch⁶ and A.M. van Tubergen⁷, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁶Ghent University Hospital, Ghent, Belgium, ⁷Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Spinal mobility is impaired in patients with ankylosing spondylitis (AS) compared to normal subjects. However, the extent of impairment and the relative contribution of…
Abstract Number: 1510 • 2013 ACR/ARHP Annual Meeting
Disease Activity In Male Smokers Has A >10-Fold Amplified Effect On Radiographic Damage In Comparison With Female NON-Smokers In Ankylosing Spondylitis
Sofia Ramiro^1,2, A.M. van Tubergen³, Robert Landewé⁴, Carmen Stolwijk⁵, Maxime Dougados⁶, Filip Van den Bosch⁷ and Désirée van der Heijde⁸, ¹Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ²Rheumatology, Hospital Garcia de Orta, Almada, Portugal, ³Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Academic Medical Center Amsterdam & Atrium Medical Center, Heerlen, Netherlands, ⁵Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁶Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: We have shown that disease activity has an effect on radiographic progression over the long-term and that gender and symptom duration are effect modifiers.…
Abstract Number: 535 • 2013 ACR/ARHP Annual Meeting
Death Receptor 3 Increases Region-Specific, Osteoblast-Dependent Aberrant New Bone Formation In The Axial Skeleton Of Mice In a Spontaneous Model Of Ankylosing Enthesopathy
Fraser L. Collins¹, Jessica O Williams², Anja C. Bloom¹, Michael D. Stone³, Ernest Choy¹, Edward C. Wang⁴ and Anwen S. Williams⁵, ¹Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ²Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine, Cardiff, United Kingdom, ³University Hospital Llandough, Cardiff & Vale University Health Board, Cardiff, United Kingdom, ⁴Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom
Background/Purpose: Clinical management of localised bone formation and joint ankylosis constitute major challenges in patients with seronegative inflammatory spondyloarthropathies (SpAs). Whether TNF receptor superfamily members,…
Abstract Number: 2495 • 2013 ACR/ARHP Annual Meeting
Ankylosing Spondylitis Protective Endoplasmic Reticulum Aminopeptidase 1 Variants Lead To Decreased Natural Killer Cell Conjugation and Activation
Hasan Abdullah¹, Zhenbo Zhang², Robert Inman³ and Nigil Haroon⁴, ¹IMS, University of Toronto, Toronto, ON, Canada, ²Toronto Western Research Institute, Toronto, ON, Canada, ³Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada, ⁴Medicine/Rheumatology, Toronto Western Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada
Background/Purpose: Ankylosing Spondylitis (AS) is an inflammatory arthritis affecting the axial and peripheral joints. Human Leukocyte Antigen (HLA)-B27 and Endoplasmic Reticulum Aminopeptidase (ERAP) 1 genes…
Abstract Number: 2448 • 2013 ACR/ARHP Annual Meeting
Cardiovascular Disease Is Associated With Worse Functional Outcomes In Ankylosing Spondylitis
Lianne S. Gensler¹, Michael M. Ward², MinJae Lee³, Mohammad Rahbar⁴, Matthew A. Brown⁵, John D. Reveille⁶ and Michael H. Weisman⁷, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, ³Medicine, University of Texas Health Science Center at Houston, Houston, TX, ⁴The University of Texas Health Science Center at Houston, Houston, TX, ⁵Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁶Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ⁷Rheumatology, Cedars-Sinai Med Ctr, Los Angeles, CA
Background/Purpose: Cardiovascular disease is an important comorbidity in inflammatory arthritis. There is evidence that AS patients have a significant burden of cardiovascular comorbidity. This appears…
Abstract Number: 1542 • 2013 ACR/ARHP Annual Meeting
Regular Exercise Is Associated With Better Functional Outcomes In Ankylosing Spondylitis
Lianne S. Gensler¹, John D. Reveille², MinJae Lee³, Mohammad Rahbar⁴, Manouchehr Ardjomand-Hessabi⁵, Matthew A. Brown⁶, Michael H. Weisman⁷ and Michael M. Ward⁸, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, ³Medicine, University of Texas Health Science Center at Houston, Houston, TX, ⁴The University of Texas Health Science Center at Houston, Houston, TX, ⁵Medicine, The University of Texas, Health Science Center at Houston, Houston, TX, ⁶Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ⁷Rheumatology, Cedars-Sinai Med Ctr, Los Angeles, CA, ⁸Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD
Background/Purpose: Exercise and physical therapy are the cornerstones of non-pharmacologic therapy in Ankylosing Spondylitis. The long-term association of exercise on function has not been evaluated.…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].