Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 2838 • 2013 ACR/ARHP Annual Meeting
Relationship Between Active Inflammatory Lesions In The Spine and Sacroiliac Joints and Development Of Fatty Lesions On Whole-Body MRI In Patients With Early Axial Spondyloarthritis- Long-Term Data Of The Esther Trial
In-Ho Song¹, Kay-Geert A. Hermann², Hildrun Haibel³, Christian Althoff⁴, Denis Poddubnyy³, Joachim Listing⁵, Anja Weiss⁶, Ekkehard Lange⁷, Bruce Freundlich⁸, Martin Rudwaleit⁹ and Joachim Sieper¹⁰, ¹Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany, ²Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Berlin, Germany, ⁴Radiology, Charite Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁵German Rheumatism Research Center, Berlin, Germany, ⁶German Rheumatism Research Centre, Berlin, Germany, ⁷BU Specialty Care, Pfizer Pharma AG, Berlin, Germany, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Endokrinologikum, Berlin, Germany, ¹⁰Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin-Franklin, Berlin, Germany
Background/Purpose : In patients with early axial spondyloarthritis (SpA) with evidence of active inflammation on magnetic resonance imaging (MRI) in the spine and/or sacroiliac (SI-)joints…
Abstract Number: 2458 • 2013 ACR/ARHP Annual Meeting
Change Over Time In The Profile Of Ankylosing Spondylitis Patients Treated With Infliximab In Canadian Routine Care
Denis Choquette¹, Michael Starr², Majed M. Khraishi³, William G. Bensen⁴, Saeed A. Shaikh⁵, Jude F. Rodrigues⁶, Dalton E. Sholter⁷, Maqbool K. Sheriff⁸, Julie Vaillancourt⁹, John S. Sampalis⁹, Allen J. Lehman¹⁰, Susan M. Otawa¹⁰, Francois Nantel¹¹ and May Shawi¹², ¹Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ²Montreal General Hospital, Montreal, QC, Canada, ³Nexus Clinical Research, St John's, NF, Canada, ⁴Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁵Medicine, McMaster University, St Catharines, ON, Canada, ⁶Rheumatology, Windsor, ON, Canada, ⁷Rheumatology Associates, Edmonton, AB, Canada, ⁸Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ⁹JSS Medical Research, Montreal, QC, Canada, ¹⁰Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹¹Janssen Inc., Toronto, ON, Canada, ¹²Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: Canadian provincial reimbursement policies in regards with infliximab coverage status have evolved in the last decade. The objective of this study was to describe…
Abstract Number: 1901 • 2013 ACR/ARHP Annual Meeting
Genetic Variants In OPG and ANKH Are Associated With Severity Ofankylosis In Ankylosing Spondylitis In a Korean Cohort
Il-Hoon Sung¹, Tae-Hwan Kim², Young Bin Joo³, So-Young Bang⁴, Seunghun Lee⁵, Kyung-Bin Joo⁶, Proton Rahman⁷, Darren D. O'Rielly⁷ and Robert Inman⁸, ¹Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Hanyang University Guri Hospital, Guri, South Korea, ⁵Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁶Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁷Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁸Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Spinal ankylosis,which represents the most severe radiologic change in ankylosing spondylitis (AS),is associated with permanent work disability as well as decreased quality of life.…
Abstract Number: 1527 • 2013 ACR/ARHP Annual Meeting
Routine Assessment Of Patient Index Data 3 Scores Correlate Well With Bath Ankylosing Spondylitis Disease Activity Index In The Assessment Of Disease Activity and Monitoring Progression Of Ankylosing Spondylitis
Abhijeet Danve¹, Kiana Vakil-Gilani², Anusha Reddy², Annan Sheffield³, Alexis Dinno⁴ and Atul A. Deodhar⁵, ¹Rheumatology, Oregon Health and Science University, Portland, OR, ²Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, ³Portland State University, Portland, OR, ⁴School of Community Health, Portland State University, Portland, OR, ⁵Oregon Health and Science University, Portland, OR
Background/Purpose: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is a composite tool unique to measure disease activity in ankylosing spondylitis (AS) just as Disease Activity…
Abstract Number: 1126 • 2013 ACR/ARHP Annual Meeting
Opportunistic Computed Tomography Screening For Determining Osteoporosis In Patients With Ankylosing Spondylitis and Spine Fractures
Amanda Cagan¹, Osa Emohare¹, Robert Morgan¹, David Polly² and Elie Gertner³, ¹Spine and Spinal Cord Injury, Regions Hospital, Saint Paul, MN, ²Division of Orthopedics, University of Minnesota, Minneapolis, MN, ³Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: In advanced disease Ankylosing Spondylitis (AS) is frequently associated with a reduction in bone mineral density (BMD) which contributes to pain and predisposes to…
Abstract Number: 2840 • 2013 ACR/ARHP Annual Meeting
Predictors Of Spinal Mobility Progression In A Multi-ethnic Cohort Of Patients With Ankylosing Spondylitis
Roozbeh Sharif¹, Trisha M. Parekh², Lianne S. Gensler³, MinJae Lee⁴, Mohammad Rahbar⁵, Laura A. Diekman⁶, Michael H. Weisman⁷, Michael M. Ward⁸, Shervin Assassi⁹ and John D. Reveille⁹, ¹Graduate School of Biomedical Science, University of Texas Medical Branch, Galveston, TX, ²Internal Medicine, University of Texas Medical Branch, Galveston, TX, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas Health Science Center at Houston, Houston, TX, ⁵The University of Texas Health Science Center at Houston, Houston, TX, ⁶Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, ⁷Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁸Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, ⁹Rheumatology, University of Texas Health Science Center at Houston, Houston, TX
Background/Purpose: Clinicians utilize several different clinical measurements (metrology) in patients with Ankylosing Spondylitis (AS) to assess the spinal mobility. We aimed to examine the pattern…
Abstract Number: 2460 • 2013 ACR/ARHP Annual Meeting
Spondyloarthritis Epidemiology and Burden Phase 2 [SPEED 2] Study: Disease Progression In Axial Spondyloarthropathy (SpA)
Eric Ruderman¹, Vibeke Strand², Avani Joshi³, Yanjun Bao³, Keith Betts⁴, Pooja Chopra⁴, Michael B. McGuire⁵ and Sumati A Rao³, ¹Northwestern University, Chicago, IL, ²Stanford University, Palo Alto, CA, ³AbbVie Inc., North Chicago, IL, ⁴Analysis Group, Inc., Boston, MA, ⁵Medical Data Analytics, Parsippany, NJ
Background/Purpose: Limited information is available on progression of non-radiographic axial spondyloarthropathy (nr-axSpA) to ankylosing spondylitis (AS) in patients with SpA meeting the Assessment of Spondyloarthritis…
Abstract Number: 1821 • 2013 ACR/ARHP Annual Meeting
Benefits Of Progressive Muscle Strengthening Using a Swiss Ball In Patients With Ankylosing Spondylitis: A Randomized Controlled Trial
Marcelo Souza¹, Fabio Jennings², Hisa Morimoto¹ and Jamil Natour³, ¹Division of Rheumatology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ²Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ³Rheumatology, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Ankylosing spondylitis (AS) is a systemic inflammatory disease that affects the physical capacity of patients globally. Exercises are recommended to the management of patients…
Abstract Number: 1537 • 2013 ACR/ARHP Annual Meeting
Primary & Subsequent Orthopedic Surgeries More Common In Juvenile Vs. Adult-Onset Ankylosing Spondylitis
Deepak R. Jadon¹, Ramani Arumugam¹, Gavin Shaddick², Alison L Nightingale³, Athimalaipet V Ramanan⁴ and Raj Sengupta¹, ¹Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ²Department of Mathematics, University of Bath, Bath, United Kingdom, ³Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, ⁴Paediatric Rheumatology, University of Bristol Hospital Trust, Bristol, United Kingdom
Background/Purpose: Patients experiencing ankylosing spondylitis (AS) symptoms ²16 years-of-age are classified as juvenile-onset AS (JoAS), whilst those ³17 years adult-onset AS (AoAS). We compared JoAS…
Abstract Number: 1032 • 2013 ACR/ARHP Annual Meeting
Shared Decision-Making In The Choice Of Biologic Medication: The Patient Perspective
Susan C. Bolge¹, Helen Eldridge² and Michael P. Ingham¹, ¹Janssen Scientific Affairs, LLC, Horsham, PA, ²Janssen Services, LLC., Titusville, NJ
Background/Purpose: There has been increasing focus on the importance of patients participating in the treatment decision-making process with their physicians. Previous research has demonstrated that…
Abstract Number: 2836 • 2013 ACR/ARHP Annual Meeting
Development of a Health Index in Patients With Ankylosing Spondylitis (ASAS HI) – Final Result of a Global Initiative Based On the International Classification of Functioning, Disability and Health (ICF) Guided By Assesment of Spondyloarthritis International Society (ASAS)
Uta Kiltz¹, Désiréé van der Heijde², Annelies Boonen³, Alarcos Cieza⁴, Gerold Stucki⁵, Muhammad Asim Khan⁶, Walter P. Maksymowych⁷, Helena Marzo-Ortega⁸, John D. Reveille⁹, Simon Stebbings¹⁰, Cristina Bostan¹¹ and Juergen Braun¹, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Department of Psychology, University Southampton, Southampton, United Kingdom, ⁵University of Lucerne, Lucerne, Switzerland, ⁶Medicine/ Rheumatology, Case Western Reserve University Hospital, Cleveland, OH, ⁷Medicine/Rheumatic Dis Unit, University of Alberta, Edmonton, AB, Canada, ⁸Leeds Musculoskeletal Biomedical Research Unit and University of Leeds, Leeds, United Kingdom, ⁹Division of Rheumatology, Univ of Texas Health Science Center at Houston, Houston, TX, ¹⁰Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, ¹¹Paraplegic Research Unit, Nottwil, Switzerland
Background/Purpose: The impact of ankylosing spondylitis (AS) on a patient’s life can be considerable. Patients suffer from pain, stiffness and fatigue, are limited in their…
Abstract Number: 2463 • 2013 ACR/ARHP Annual Meeting
Tomosynthesis As a New Diagnostic Tool For Evaluation Of Ankylosing Spondylitis With Modified Stoke Ankylosing Spondylitis Spinal Score: A Comparison With Plain Radiographs
Seunghun Lee¹, Tae-Hwan Kim², Jae-Bum Jun², Kyung-Bin Joo³, Young Bin Joo⁴ and Jina Park⁵, ¹Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁵Department of Radiology, Hanyang University Hospital, Seoul, South Korea
Background/Purpose: In assessment of ankylosing spondylitis (AS), accurate scoring of modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) is important to evaluate the treatment effects or…
Abstract Number: 1798 • 2013 ACR/ARHP Annual Meeting
Ustekinumab For The Treatment Of Patients With Active Ankylosing Spondylitis: Results Of a 28-Week, Prospective, Open-Label, Proof-Of-Concept Study (TOPAS)
Denis Poddubnyy¹, Johanna Callhoff², Joachim Listing² and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Center, Berlin, Germany
Background/Purpose: In contrast to other inflammatory rheumatic diseases, such as rheumatoid arthritis, the therapeutic options in ankylosing spondylitis (AS) with predominant axial manifestations are limited…
Abstract Number: 1538 • 2013 ACR/ARHP Annual Meeting
The Age At Onset Of Symptoms Influence The Clinical Expression Of The Disease In Patients With Ankylosing Spondylitis
Natalia Zamora¹, Emilce Edith Schneeberger¹, Luis Alejandro Cayetti², Fernando Sommerfleck¹ and Gustavo Citera¹, ¹Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: The onset of symptoms before 10 years and after 40 years is uncommon in patients with ankylosing spondylitis (AS). Some authors have found specific…
Abstract Number: 1033 • 2013 ACR/ARHP Annual Meeting
Psychological status correlates of disease activity and sleep quality in patients with Ankylosing Spondylitis: A case-control study
Mingcan Yang¹, Yutong Jiang², Zhiming Lin³, Zetao Liao⁴, Qiuxia Li⁴, Yanli Zhang¹ and Jieruo Gu⁵, ¹Rheumatology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Rheumatology, Third affiliated hospital of Sun Yat-sen University, Guangzhou, China, ³Rheumatology, third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China, ⁴Rheumatology, The Affiliated Third Hospital of Sun Yat-san University, Rheumatology, Guangzhou, China, ⁵Medicine, Third Affiliated Hospital of Sun Yat-sen University, GuangZhou, China
Background/Purpose: The objective of this study was to compare psychological status and sleep quality between the patients with AS patients and healthy controls, and to discover the correlation between anxiety, depression and sleep disturbances, to evaluate the associated factors of disease specific variables in AS patients and to detect independent factors contributing to psychological variables. Methods: A nationwide face-to-face epidemiological investigation was performed in multiple centers of China. The demographic data , clinical symptoms/signs and psychological assessment data including Zung self-rating anxiety scale (SAS), Zung self-rating depression scale (SDS) and the Pittsburgh Sleep Quality Index questionnaire (PSQI) were collected using questionnaires. Mann-Whitney U test and t test was used in independent groups for parametric variables, whereas the Spearman correlation analysis and multiple stepwise regression analysis were used to assess correlation between parametric variables. Results: 683 AS patients by the revised New York criteria for AS and 697 age-, sex-, education-matched healthy controls were enrolled in the study.(1) Compared with healthy controls, AS patients suffered from more severe psychological disorders and sleep disturbance（P

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