ACR Meeting Abstracts

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Abstracts tagged "ANCA associated vasculitis"

  • Abstract Number: 1431 • ACR Convergence 2020

    Interstitial Lung Disease in Patients with ANCA Associated Vasculitis – a Prospective Single Centre Study

    Alojzija Hocevar1, Katja Perdan Pirkmajer1, Matija Tomsic1 and Ziga Rotar1, 1University Medical Center Ljubljana, LJUBLJANA, Slovenia

    Background/Purpose: Recently, an association between anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and interstitial lung disease (ILD) has been uncovered. We aimed to determine the rate…
  • Abstract Number: 0060 • ACR Convergence 2020

    ANCA-associated Vasculitis in Caucasian and Hispanics of the Inland Empire of Southern California

    Sandy Lee1, Patil Injean1, Paulina Tran2, Deepa Panikkath1 and Christina Downey1, 1Loma Linda University Medical Center, Redlands, CA, 2UC Riverside School of Medicine, Riverside, CA

    Background/Purpose: ANCA-associated vasculitis (AAV) is often studied in the Caucasian population with few studies looking at the disease in other races. Disease presentation and treatment…
  • Abstract Number: 1432 • ACR Convergence 2020

    Thyroid Disease in Patients with ANCA-Associated Vasculitis

    Tanaz Kermani1, David Cuthbertson2, Simon Carette3, Nader Khalidi4, Curry L. Koening5, Carol Langford6, Carol McAlear7, Paul Monach8, Larry Moreland9, Christian Pagnoux10, Philip Seo11, Ulrich Specks12, Antoine Sreih13, Kenneth Warrington12 and Peter Merkel13, 1University of California Los Angeles, West Hills, CA, 2University of South Florida, Tampa, 3Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, 4McMaster University, Hamilton, ON, Canada, 5University of Utah, Salt Lake City, 6Cleveland Clinic, Moreland Hills, OH, 7University of Pennsylvania, Philadelphia, 8Brigham and Women's, Boston, 9University of Pittsburgh, Denver, CO, 10Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Department of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 11Johns Hopkins University, Baltimore, MD, 12Mayo Clinic, Rochester, MN, 13University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Prior studies have found increased prevalence of thyroid disease in patients with ANCA-associated vasculitis (AAV), especially positive myeloperoxidase (MPO)-ANCA, but a majority of the…
  • Abstract Number: 0418 • ACR Convergence 2020

    Prevalence of Thyroid Disease Among Patients with Vasculitis

    Tanaz Kermani1, David Cuthbertson2, Simon Carette3, Nader Khalidi4, Curry L. Koening5, Carol Langford6, Carol McAlear7, Paul Monach8, Larry Moreland9, Christian Pagnoux10, Philip Seo11, Ulrich Specks12, Antoine Sreih13, Kenneth Warrington12 and Peter Merkel13, 1David Geffen School of Medicine / University of California, Los Angeles, CA, 2University of South Florida, Tampa, 3Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, 4McMaster University, Hamilton, ON, Canada, 5University of Utah, Salt Lake City, 6Cleveland Clinic, Moreland Hills, OH, 7University of Pennsylvania, Philadelphia, 8Brigham and Women's, Boston, 9University of Pittsburgh, Denver, CO, 10Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 11Johns Hopkins University, Baltimore, MD, 12Mayo Clinic, Rochester, MN, 13University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Previous studies have reported higher risk of thyroid disease in patients with giant cell arteritis (GCA) and ANCA-associated vasculitis (AAV) compared to age- and…
  • Abstract Number: 1433 • ACR Convergence 2020

    Thyroid Disease in ANCA-associated Vasculitis. a Population-based Study

    Anna Wilding1, Rona Smith2, David Jayne3, Mårten Segelmark4 and Aladdin Mohammad5, 1Lund University, Staffanstorp, Sweden, 2University of Cambridge, Cambridge, United Kingdom, 3Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom, 4Lund University, Lund, 5Lund University, Lund, Sweden. Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Lund, Sweden

    Background/Purpose: A higher incidence of thyroid disease has been seen in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We aim to assess the incidence…
  • Abstract Number: 0432 • ACR Convergence 2020

    The Effect on Renal Function of the Complement C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis

    Peter Merkel1, Pirow Bekker2, Huibin Yue2, Catherine Kelleher2, Thomas Schall2 and David Jayne3, 1University of Pennsylvania, Philadelphia, PA, 2ChemoCentryx, Mountain View, CA, 3Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom

    Background/Purpose: Avacopan, a novel, orally-administered selective antagonist of C5aR, was recently evaluated in a pivotal Phase 3 randomized clinical trial where its use in patients…
  • Abstract Number: 1434 • ACR Convergence 2020

    The Role of Sural Nerve Biopsy in the Diagnosis of Systemic Vasculitis – a Retrospective Study from Two Specialized Centres

    Karl Gisslander1, Lars Dahlin2, Rona Smith3, David Jayne3 and Aladdin Mohammad4, 1Lund University, Lund, Sweden, Lund, Sweden, 2Department of Translational Medicine – Hand Surgery, Lund University, Malmö, Sweden, Malmö, Sweden, 3Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom, 4Lund University, Lund, Sweden. Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Lund, Sweden

    Background/Purpose: Vasculitis of the peripheral nervous system is seen mainly in systemic vasculitis involving small and medium sized vessels and in cases of single-organ vasculitis…
  • Abstract Number: 0566 • ACR Convergence 2020

    Healthcare Utilization and Costs Prior to Diagnosis of ANCA Vasculitis in Medicare Beneficiaries

    Shirley Huang1, Xintong Li2, Joehl Nguyen2, Jacob Robinson2, Susan Hogan3, Vimal Derebail3 and Carolyn Thorpe2, 1University of North Carolina at Chapel Hill, Chapel Hill, 2University of North Carolina Eshelman School of Pharmacy, Chapel Hill, 3University of North Carolina Kidney Center, Chapel Hill

    Background/Purpose: Antineutrophil cytoplasmic antibody (ANCA) vasculitis (AV) is a complex group of autoimmune disorders affecting blood vessels in multiple organ systems. Delays in diagnosis are…
  • Abstract Number: 1435 • ACR Convergence 2020

    Prognostic Factors for Mononeuritis Multiplex Associated with ANCA-associated Vasculitis

    Yutaro Hayashi1, Satoshi Hama2, Keisuke Izumi2, Mari Ushikubo1, Misako Konishi3, Yutaka Okano4 and Hisaji Ohshima2, 1Tokyo medical center, Tokyo, Japan, 2Department of Connective Tissue Diseases, National Hospital Organization Tokyo Medical Center, tokyo, Japan, 3Tokyo medical center, toukyouto Meguroku, Japan, 4Department of Connective Tissue Diseases, National Hospital Organization Tokyo Medical Center, Kawasaki, Japan

    Background/Purpose: ANCA-associated vasculitis (AAV) sometimes presents mononeuritis multiplex which worsens the prognosis and activity of daily living in patients. This study aimed to determine theprognostic factorsand…
  • Abstract Number: 0622 • ACR Convergence 2020

    Infection-induced MPO-ANCA Associated Vasculitis: A Systematic Review of Published Case Reports

    Konstantinos Parperis1, Loukas Kakoullis2, Eleni Papachristodoulou3 and George Panos3, 1University of Arizona College of Medicine Phoenix and University of Cyprus Medical School, Phoenix, 2University of Patras School of Health Sciences, Patras, Akhaia, Greece, 3University of Cyprus Medical School, Nicosia, Nicosia, Cyprus

    Background/Purpose: Anti-myeloperoxidase (MPO) antineutrophil cytoplasmic antibody (ANCA) has been implicated in the pathogenesis of microscopic polyangiitis (MPA) and an MPO-ANCA associated glomerulonephritis; both conditions are…
  • Abstract Number: 1437 • ACR Convergence 2020

    Measuring Disease Activity and Functional Status in Patients with Granulomatosis with Polyangiitis (Wegener’s) (GPA)

    Kinanah Yaseen1, Isaac Briskin1 and Rula Hajj-ali2, 1Cleveland Clinic Foundation, Cleveland, 2Cleveland Clinic, Cleveland, OH

    Background/Purpose: Variable association between vasculitis activity and patient reported outcomes was reported in small groups of Granulomatosis with polyangiitis (GPA) patients in the literature so…
  • Abstract Number: 1032 • ACR Convergence 2020

    Epidemiology and Geographic Evaluation of ANCA-associated Vasculitis (AAV) at a Rural Academic Health Center Utilizing an Electronic Health Record (EHR)

    Eva Rottmann1, Jason Bankert2, Andrea Berger2, Lester Kirchner2, Joseph Dewalle2, Marissa Meissner3, Jason George2, Ion Dan Bucaloiu2, Jaya Prakash Sugunaraj2, Sudheer Penupolu2 and David Bulbin1, 1Geisinger Health System, Danville, PA, 2Geisinger Medical Center, Danville, PA, 3Geisinger Medical Center, Danville

    Background/Purpose: ANCA-associated vasculitis has a reported prevalence ranging from 3.2 to 9.1 cases per 100,000 individuals, but little is known of geographic variations. The aim of…
  • Abstract Number: 1438 • ACR Convergence 2020

    Rituximab Immunogenicity in ANCA-associated Vasculitis (RITUXIMAV)

    Jason Springer1 and Ryan Funk2, 1University of Kansas Medical Center, Overland Park, KS, 2UNIVERSITY OF KANSAS, Kansas City, KS

    Background/Purpose: Rituximab (RTX), an anti-CD20 chimeric monoclonal antibody, has been shown to be an effective maintenance therapy for granulomatosis with polyangitiis (GPA) and microscopic polyangiitis…
  • Abstract Number: 1417 • ACR Convergence 2020

    Risk of Relapse of ANCA-associated Vasculitis in Patients of 75 Years and Older: A Retrospective Study

    Sara Thietart1, Guillaume Beinse2, Perrine Smets3, Alexandre Karras4, Carole Philipponnet5, Jean-François Augusto6, Khalil El Karoui7, Rafik Mesbah8, Dimitri Titeca Beauport9, Mohamed Hamidou10, Pierre-Louis Carron11, Julien Campagne12, Karim Sacre13, Pascal Cohen1, Eric Liozon14, Claire Blanchard-Delaunay15, Alex Kostianovsky16, Christian Pagnoux17, Luc Mouthon1, Loïc Guillevin18, Benjamin Terrier1 and Xavier Puéchal for the French Vasculitis Study Group1, 1National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University, Paris, France, 2Inserm UMR 1138, Centre de Recherche des Cordeliers, Paris, France, 3Department of Internal Medicine, Centre Hospitalier Universitaire Clermont-Ferrand Hôpital Gabriel-Montpied, Clermont Ferrand, France, 4Department of Nephrology, Hôpital Européen Georges Pompidou, Paris, France, 5Department of Nephrology, CHU Clermont-Ferrand, Clermont-Ferrand, Clermont Ferrand, France, 6Department of Nephrology-Dialysis-Transplantation, CHU Angers, Angers, France, 7Department of Nephrology and Transplantation, Hôpital Universitaire Henri-Mondor, Creteil, France, 8Department of Nephrology, CH Boulogne-sur-Mer, Boulogne-Sur-Mer, France, 9Department of Nephrology, Amiens University Medical Center, Amiens, France, 10Department of Internal Medicine, Hôtel-Dieu, CHU Nantes, Nantes, France, 11Department of Nephrology-Dialysis-Transplantation, CHU Grenoble-Alpes, Grenobles, France, 12Department of Internal Medicine, Hôpitaux Privés de Metz, Metz, France, 13Département de Médecine Interne, Hôpital Bichat, APHP, Paris, France, 14Department of Internal Medicine and Clinical Immunology, Limoges University Hospital, Limoges, France, 15Department of Internal Medicine, CH, Niort, France, 16Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno", Buenos Aeres, Argentina, 17Vasculitis Clinic, Canadian Network for Research on Vasculitides (CanVasc), Department of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 18Department of Internal Medecine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris-Descartes University, Paris, France

    Background/Purpose: ANCA-associated vasculitis (AAV) frequently occurs among older patients, with different clinical presentations than the younger. Little is known on the outcome of older patients…
  • Abstract Number: 1439 • ACR Convergence 2020

    Proteinase 3-Reactive B Cell Pool Restructuring After Rituximab and Risk of Relapse in Severe PR3-ANCA-Associated Vasculitis

    Alvise Berti1, Sophie Hillion2, Marta Casal Moura1, Amber Hummel1, Eva Carmona1, Tobias Peikert1, Carol Langford3, Peter A. Merkel4, Paul Monach5, Philip Seo6, Robert Spiera7, Eugene St Clair8, Fernando C. Fervenza1, Kristina Harris9, John H. Stone10, Jacques-Olivier Pers11, Ulrich Specks1 and Divi Cornec12, 1Mayo Clinic, Rochester, MN, 2Brest University, Brest, Bretagne, France, 3Cleveland Clinic, Moreland Hills, OH, 4Division of Rheumatology University of Pennsylvania, Philadelphia, PA, 5Brigham and Women's, Boston, 6Johns Hopkins University, Baltimore, MD, 7Division of Rheumatology, Hospital for Special Surgery, New York, New York, USA, New York, NY, 8Duke University, Durham, NC, 9Immune Tolerance Network, Bethesda, MD, 10Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, 11University of Brest, Brest, France, 12Rheumatology Department, Brest University Hospital, Brest, France

    Background/Purpose: In ANCA-associated vasculitis (AAV) B cells play a central pathogenic role and are instrumental for the production of ANCA, which are thought to mediate…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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