ACR Meeting Abstracts

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Abstracts tagged "Aging"

  • Abstract Number: 1974 • ACR Convergence 2020

    Validation of a Deep Learning Based Algorithm to Diagnose Vertebral Compression Fractures

    John Page1, Franklin Moser2, Marcel Maya3, Ravi Prasad3 and Barry Pressman2, 1Amgen, Inc, Thousand Oaks, CA, 2Cedars-Sinai Medical Center, Los Angeles, CA, 3Cedars-Sinai Medical Center, Los Angeles

    Background/Purpose: Vertebral Compression Fractures are common in patients above age 50, but are often undiagnosed.  Patients with one VCF are at higher risk of other…
  • Abstract Number: 2039 • ACR Convergence 2020

    Short Telomeres and Autoantibodies Targeting Telomere-Associated Proteins in Scleroderma

    Britany Adler1, Ami Shah2, Francesco Boin3, Paul Wolters3, Livia Casciola-Rosen4 and Antony Rosen1, 1Johns Hopkins University, baltimore, MD, 2Johns Hopkins University School of Medicine, Ellicott City, MD, 3University of California, San Francisco, San Francisco, CA, 4Johns Hopkins University, Johns Hopkins University, MD

    Background/Purpose: Scleroderma is a systemic fibrosing disease of unknown etiology that often manifests with interstitial lung disease (ILD). Prior studies have found an association between…
  • Abstract Number: 0351 • ACR Convergence 2020

    Ustekinumab-Treated Patients with Psoriatic Arthritis in a Real-world Study: Similar Clinical Responses and Treatment Persistence over One Year in Elderly and Younger Patients

    Laure Gossec1, Elke Theander2, Soumya Chakravarty3, Paul Bergmans4, Iris Lin5, Wim Noël6, Stefan Siebert7 and Josef Smolen8, 1Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, 2Janssen Cilag, Lund, Sweden, 3Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, 4Janssen Biostatistics and Medical Affairs, Tilburg, Netherlands, 5Janssen Immunology Global Commercial Strategy Organization, Horsham, 6Janssen Medical Affairs, LLC, Beerse, Belgium, 7University of Glasgow, Glasgow, United Kingdom, 8Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria

    Background/Purpose: In the PsABio study (NCT02627768), real-world data from patients with PsA showed comparable clinical results after treatment with ustekinumab (UST, an anti-p40 IL-12/23 inhibitor)…
  • Abstract Number: 0422 • ACR Convergence 2020

    Frailty and Health-Related Quality of Life in Patients with Polymyalgia Rheumatica

    Sebastian Sattui1, Deanna Jannat-Khah2, Lindsay Lally1, Sarah Lieber1, Lisa Mandl1 and Robert Spiera3, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York City, NY, 3Division of Rheumatology, Hospital for Special Surgery, New York, New York, USA, New York, NY

    Background/Purpose: Frailty is a syndrome characterized by an increased vulnerability to stressors. Frailty and pre-frailty have been reported in 10% and 44%of community dwelling elderly,…
  • Abstract Number: 0612 • ACR Convergence 2020

    Differences in 30-Day Rehospitalization Risk and Predictors by Age Group Among Patients with Lupus in Medicare

    Maria Schletzbaum1, Yi Chen2, Ann Sheehy3, Farah Kaiksow3, Ryan Powell4, Andrea Gilmore-Bykovskyi5, Amy Kind6 and Christie Bartels7, 1University of Wisconsin-Madison School of Medicine and Public Health, Department of Population Health Sciences, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Department of Biostatistics and Medical Informatics, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Department of Medicine, Hospital Medicine Division, Madison, WI, 4University of Wisconsin School of Medicine and Public Health, Department of Medicine, Geriatrics Division, Madison, WI, 5University of Wisconsin - Madison, School of Nursing, Madison, WI, 6University of Wisconsin-Madison School of Medicine and Public Health, Department of Medicine, Health Services and Care Research Program, Geriatrics Division, Madison, WI, 7University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI

    Background/Purpose: Although our recent research demonstrates that young adult Medicare beneficiaries (age 18-35) with lupus (SLE) have higher risk of 30-day rehospitalization, predictors specific to…
  • Abstract Number: 0624 • ACR Convergence 2020

    Association of Regional Body Composition and Physical Function Using the Short Physical Performance Battery Among Peruvian Women with HIV

    Diego Cabrera1, Mijahil Pavel Cornejo Ortega2, Yvett Pinedo3, Patricia Garcia4 and Evelyn Hsieh5, 1Yale University, Universidad Peruana Cayetano Heredia, Lima, Peru, 2Hospital Nacional Arzobispo Loayza, Lima, Peru, 3Hospital Nacional Arzobispo Loayza, Lima, 4Universidad Peruana Cayetano Heredia, Lima, Peru, 5Yale University School of Medicine; West Haven VA, New Haven, CT

    Background/Purpose: The musculoskeletal (MSK) system is significantly affected by HIV and its treatment. Changes in body composition can reflect important changes in bone and MSK…
  • Abstract Number: 0693 • ACR Convergence 2020

    Effect of Physical Activity on Cartilage Degradation and Inflammation in Individuals with Lumbar Spinal Stenosis

    Gustavo Almeida1, Samannaaz Khoja2, Lauren Terhorst3, Gwendolyn Sowa4, Sara Piva2 and Michael Schneider2, 1Department of Physical Therapy, UT HEALTH SAN ANTONIO, San Antonio, TX, 2Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, 3Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA, 4Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Guidelines recommend 150 minutes a week in moderate-intensity physical activity (MPA) to improve health in individuals with chronic disease such as those with lumbar…
  • Abstract Number: 0694 • ACR Convergence 2020

    Relationships Among Adherence and Patient Outcomes in a Cognitive Behavioral Plus Physical Activity Intervention for Older Adults with Osteoarthritis and Hypertension

    Xiaojun Shi1, Elizabeth Schlenk2 and Susan Sereika1, 1University of Pittsburgh School of Nursing, Pittsburgh, 2University of Pittsburgh School of Nursing, Pittsburgh, PA

    Background/Purpose: Osteoarthritis of the knee (OAK) affects nearly 14 million older adults and more than half are diagnosed with hypertension (HTN). Cognitive behavior therapy (CBT)…
  • Abstract Number: 0709 • ACR Convergence 2020

    Anatomical Distribution of Mrgprd-expressing Nonpeptidergic C-fibers in the Mouse Knee

    Alia Obeidat1, Rachel Miller1 and Anne-Marie Malfait1, 1Rush University, CHICAGO, IL

    Background/Purpose: The voltage-gated sodium channel, NaV1.8, marks the majority of C-fiber nociceptors. We have used NaV1.8 tdTomato reporter mice to describe the nociceptive innervation of…
  • Abstract Number: 0807 • ACR Convergence 2020

    Safety of Biologic & Targeted Therapies Among Elderly Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

    Akhil Sood1, Soham Al Snih1, Vijaya Murthy2, Emilio Gonzalez1 and Mukaila Raji1, 1University of Texas Medical Branch, Galveston, TX, 2University of Texas Medical Branch, League City, TX

    Background/Purpose: Recent developments in biologic and targeted therapy have led to better control of disease activity and improved quality of life in patients with rheumatoid…
  • Abstract Number: 1298 • ACR Convergence 2020

    Lupus Damage Free-Survival by Age at Diagnosis: A Retrospective Incident Lupus Cohort

    Maria Schletzbaum1, Nnenna Ezeh2, Trevor McKown3, Shivani Garg4 and Christie Bartels5, 1University of Wisconsin-Madison School of Medicine and Public Health, Department of Population Health Sciences, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Milwaukee, WI, 3William S. Middleton Memorial Veterans Hospital, Madison, WI, 4UW Madison, Madison, WI, 5University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI

    Background/Purpose: While medical comorbidities increase with age, younger age at onset of Systemic Lupus Erythematosus (SLE) has been associated with greater risk of some types…
  • Abstract Number: 1325 • ACR Convergence 2020

    Monoclonal Gammopathy in Psoriatic Arthritis

    Vanessa Ocampo1 and Dafna Gladman2, 1University of Toronto, University Health Network, Psoriatic Arthritis Research Program, Toronto, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant clonal plasma disorder, defined by the presence of a serum monoclonal protein (M-protein) at…
  • Abstract Number: 1408 • ACR Convergence 2020

    Metabolic Reprogramming in Memory CD4+ T Cells Is Associated with Immune Cell Dysfunction During Aging

    Yuling Chen1, Yuanchun Ye2, Hao Wu3, Pierre-Louis Krauß1, Pelle Löwe1, Moritz Pfeiffenberger1, Lisa Ehlers1, Thomas Buttgereit4, Paula Hoff5, Frank Buttgereit6 and Timo Gaber1, 1Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Rheumatology and Clinical Immunology, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Hematology, Oncology and Tumor Immunology, Berlin, Germany, 3Julius-Maximilians Universität Würzburg, Institut für Systemimmunologie, Würzburg, Germany, 4Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venerology, and Allergology, Berlin, Germany, 5Endokrinologikum Berlin, Rheumatologie, Berlin, Germany, 6Charité University Medicine, Berlin, Germany

    Background/Purpose: Inflamm-aging is a chronic, sterile, low-grade inflammatory status, characterized by an increase of proinflammatory cytokines which participate in the development of most age-related diseases…
  • Abstract Number: 332 • 2018 ACR/ARHP Annual Meeting

    Components of Impaired Physical Function and Disability in a Non-Rheumatic Population. Normative Values of the Health Assessment Questionnaire Disability Index

    C Alejandro Arce-Salinas1, H FABRICIO ESPINOSA-ORTEGA2 and Olivia Enriquez-Antonio3, 1INTERNAL MEDICINE, Hospital Central Sur PEMEX, MEXICO, Mexico, 2Rheumatology Department, Karolinska Universitetssjukhuset, Stockolm, Sweden, 3Internal Medicine, Hospital Central Sur PEMEX, mexico, Mexico

    Background/Purpose: HAQ-Di is broadly used to measure disability in RA, its assessment might influence taking decision process. However, it cannot differentiate disability related to arthritis,…
  • Abstract Number: 1034 • 2018 ACR/ARHP Annual Meeting

    A Conplastic Mice Model of Aging Reveals That Mitochondrial DNA Variation Influences the Process of Joint Deterioration

    Ignacio Rego-Pérez1, Ana Victoria Lechuga-Vieco2, Morena Scotece1, Purificación Filgueira-Fernández1, Sonia Pertega3, Jose Antonio Enríquez2 and Francisco J Blanco4, 1Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain, 2Grupo de Genética funcional del sistema de fosforilación oxidativa. Centro Nacional de Investigaciones Cardiovasculares (CNIC). C/Melchor Fernández de Almagro, 3, 2 Sur. 28029. Madrid, España, Madrid, Spain, 3Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, 4Grupo de Investigación en Reumatología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain

    Background/Purpose: Different studies showed interesting genetic associations between mtDNA haplogroups and OA-related features, including prevalence, incidence and progression of the disease. The aim of this…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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