ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "ACR"

  • Abstract Number: 650 • 2019 ACR/ARP Annual Meeting

    Performance of the Proposed American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Lupus Erythematosus in Korean Patients

    Eunyoung Lee1, Eun Bong Lee 2, Eun Young Lee 1, Jin Kyun Park 3, Se Han Ahn 4 and Yeong-Wook Song 5, 1Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Seoul, Republic of Korea, 2Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, seoul, 3Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Seoul, Seoul-t'ukpyolsi, Republic of Korea, 4Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Gwacheon-si, Kyonggi-do, Republic of Korea, 5Seoul National University Hospital, Seoul, Republic of Korea

    Background/Purpose: To evaluate the performance of the proposed American College of Rheumatology/European League against Rheumatism (ACR/EULAR) classification criteria for systemic lupus erythematosus (SLE) in Korean…
  • Abstract Number: 1348 • 2019 ACR/ARP Annual Meeting

    Impact of Tofacitinib on the Individual Components of the ACR Composite Score in Patients with Rheumatoid Arthritis: A Post Hoc Analysis of Phase 3 Trials

    Louis Bessette1, Maxime Dougados 2, Eduardo Mysler 3, Mark Genovese 4, Cassandra Kinch 5, Kenneth Kwok 6, Tatjana Lukic 6, Tanya Girard 5, Pierre-Alexandre Landry 5 and Ronald van Vollenhoven 7, 1Laval University, Quebec City, QC, Canada, 2Cochin Hospital, Paris, France, 3Organización Médica de Investigación, Buenos Aires, Argentina, 4Stanford University, Stanford, CA, 5Pfizer Canada ULC, Kirkland, QC, Canada, 6Pfizer Inc, New York, NY, 7Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands

    Background/Purpose: Tofacitinib is an oral JAK inhibitor for the treatment of RA. In clinical trials, standard criteria for measuring treatment efficacy in patients (pts) with…
  • Abstract Number: 1484 • 2019 ACR/ARP Annual Meeting

    The Impact of Time Since First Diagnosis on the Efficacy and Safety of Tofacitinib in Patients with Active Psoriatic Arthritis

    Peter Nash1, Maria Greenwald 2, Liang-Hung Lin 3, Wei Yu 4, Paul Santos Estrella 5, Rajiv Mundayat 6, Daniela Graham 7 and Douglas Veale 8, 1University of Queensland, Brisbane, Queensland, Australia, 2Desert Medical Advances, Palm Desert, CA, 3AIR, Taichung Tzu Chi Hospital, Taichung City, Taiwan (Republic of China), 4Pfizer Inc, Beijing, China (People's Republic), 5Pfizer Inc, Makati, Philippines, 6Pfizer Inc, New York, NY, 7Pfizer Inc, Groton, CT, 8EULAR Centre For Arthritis And Rheumatic Diseases and The Conway Institute, Dublin, Ireland

    Background/Purpose: Early identification, diagnosis, and treatment of psoriatic arthritis (PsA) is important in preventing long-term joint damage and disability, and the associated socioeconomic consequences.1 Tofacitinib…
  • Abstract Number: 588 • 2018 ACR/ARHP Annual Meeting

    Acr Hybrid Analysis: Blinded Data from the Ongoing Phase IIb Trial with the EP4 Receptor Antagonist CR6086 in DMARD-Naïve Patients with Early Rheumatoid Arthritis

    Cristina Vitalini, Beatrice Barbetta, Giampaolo Giacovelli, Nadia Brambilla, Massimo D'Amato, Federica Girolami and Lucio C. Rovati, Clinical Research Department, Rottapharm Biotech, Monza, Italy

    Background/Purpose: The ACR Hybrid, officially recommended by the ACR as a revision to the ACR20/50/70 response criteria, combines the ACR20/50/70 scores with the mean percent…
  • Abstract Number: 1188 • 2018 ACR/ARHP Annual Meeting

    Are Residents Choosing Wisely? Analysis of Adherence to Recommendations of Ordering Anti-Nuclear Antibody Testing in an Internal Medicine Residency Primary Care Clinic

    Aparna Das, Rajarajan Panneerselvan, Annum Faisal, Jubran Rind and Rima Shah, Internal medicine, Michigan state university, grand rapids, MI

    Background/Purpose: A positive anti-nuclear antibody (ANA) is considered very useful for the diagnosis of SLE and systemic sclerosis, and somewhat useful for the diagnosis of…
  • Abstract Number: 1254 • 2018 ACR/ARHP Annual Meeting

    QI Project: Inpatient Practices in Ordering Fluorescent Anti-Nuclear Antibodies (F-ANA) and ANA Subserologies in a City Hospital in an Underserved Community

    Ivan Emil Ramirez de Oleo1, Beverly Johnson2,3 and Barbara Mendez-Agrusa4, 1Internal Medicine, Jacobi Medical Center, Bronx, NY, 2Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, 3Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 4Medicine, Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: It is important for internists to know how to appropriately and effectively order subspecialty labs. As part of the choosing wisely campaign in 2013,…
  • Abstract Number: 1681 • 2018 ACR/ARHP Annual Meeting

    Performance of the Proposed American College of Rheumatology / European League Against Rheumatism 2017 Classification Criteria for SLE in Adult and Juvenile Systemic Lupus Erythematosus and Other Anti-Nuclear Antibody Related Rheumatic Diseases

    Chengappa KG1, Gunjan Kumar2, Swaminathan R P3 and Vir Singh Negi1, 1Clinical Immunology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India, 2Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India, 3Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India

    Background/Purpose: A new classification criteria for SLE was proposed at the ACR/ARHP 2017 annual meet. The aim of this study was to compare the performance…
  • Abstract Number: 2578 • 2018 ACR/ARHP Annual Meeting

    Exposure Response Analyses to Describe the Relationship between Ixekizumab Concentrations and Acr Responses in Psoriatic Arthritis Patients

    C. Steven Ernest II, Nieves Velez de Mendizabal and Leijun Hu, Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: Ixekizumab is a high-affinity monoclonal antibody that selectively targets interleukin (IL)-17A. It has been approved to treat adult patients with moderate-to-severe plaque psoriasis and…
  • Abstract Number: 17L • 2017 ACR/ARHP Annual Meeting

    Subcutaneous Secukinumab Inhibits Radiographic Progression in Psoriatic Arthritis: Primary Results from a Large Randomized, Controlled, Double-Blind Phase 3 Study

    Philip J Mease1, Désirée van der Heijde2, Robert B.M. Landewé3, Shephard Mpofu4, Proton Rahman5, Hasan Tahir6, Atul Singhal7, Elke Böttcher8, Sandra V. Navarra9, Karin Meiser4, Aimee Readie10, Luminita Pricop10 and Ken Abrams10, 1Swedish Medical Center and University of Washington, Seattle, WA, 2Leiden University Medical Center, Leiden, Netherlands, 3Academic Medical Center, Amsterdam and Atrium Medical Center, Heerlen, Netherlands, 4Novartis Pharma AG, Basel, Switzerland, 5Rheumatology, Memorial University of Newfoundland, St Johns, NF, Canada, 6Whipps Cross Hospital, London, United Kingdom, 7Southwest Rheumatology, Dallas, TX, 8Rheumazentrum Favoriten, Vienna, Austria, 9Rheumatology, University of Santo Tomas Hospital, Manila, Philippines, 10Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: Secukinumab, a fully human monoclonal antibody that selectively neutralizes IL-17A, has shown significant and rapid efficacy in psoriatic arthritis (PsA). We present primary results…
  • Abstract Number: 624 • 2017 ACR/ARHP Annual Meeting

    Ixekizumab Provides Sustained Improvement in Signs and Symptoms in Patients with Active Psoriatic Arthritis: Two Year Results from a Phase 3 Trial

    Philip S. Helliwell1, Eric Lespessailles2, Catherine Shuler3, Lotus Mallbris3, Janelle Erickson3 and Roy Fleischmann4, 1St. Luke's Hospital and University of Leeds, Bradford, United Kingdom, 2University Orleans, Orleans, France, 3Eli Lilly and Company, Indianapolis, IN, 4Metroplex Clinical Research Center, Dallas, TX

    Background/Purpose: Ixekizumab (IXE) is a high affinity monoclonal antibody that selectively targets IL-17A. In the SPIRIT-P1 phase 3 study (NCT01695239), IXE was superior to placebo…
  • Abstract Number: 734 • 2017 ACR/ARHP Annual Meeting

    Correlation of the American College of Rheumatology Provisional Composite Response Index in Systemic Sclerosis with Serum Biomarkers of Fibrogenesis in an Observational Cohort

    Giuseppina Abignano1, Sookhoe Eng2, Maya H. Buch3, Paul Emery4, Dinesh Khanna5 and Francesco Del Galdo2, 1Rheumatology Department of Lucania,, Rheumatology Institute of Lucania (IReL), San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera,, Potenza, Italy, 2Leeds Musculoskeletal Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 3NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 4NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5University of Michigan, Ann Arbor, MI

    Background/Purpose: The CRISS is a composite index of response in diffuse cutaneous systemic sclerosis (dcSSC). It is a 2-step process for the probability of improvement…
  • Abstract Number: 1556 • 2017 ACR/ARHP Annual Meeting

    Efficacy of Biologics and New Anti-Inflammatory Agents Used in the Treatment of Active Psoriatic Arthritis: Systematic Literature Review and Network Meta-Analysis of the Evidence.

    Mahdi Gharaibeh1, Yingxin Xu2, Joseph Lee3, Madhura Chitnis2 and David Collier4, 1Amgen Inc., Thousand Oaks, CA, 2Evidera, Bethesda, MD, 3videra, Bethesda, MD, 4Amgen, Inc, Terni, Italy

    Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Biologics are usually the first-line FDA-approved disease-modifying anti-rheumatic drug (DMARD) treatment; however, no published…
  • Abstract Number: 2280 • 2017 ACR/ARHP Annual Meeting

    Effectiveness of Switching to Adalimumab As the Second- and Third-Line Biological Drug in Patients with Juvenile Idiopathic Arthritis

    Ekaterina Alexeeva1, Tatiana Dvoryakovskaya2, Victor Gladkikh3,4, Andrei Moskalev4,5, Rina Denisova1, Ksenia Isaeva1, Olga Lomakina1, Margarita Soloshenko1 and Anna Karaseva1, 1Reumatology department, Federal State Autonomous Institution"National Scientific and Practical Center of Children's Health"Of the Ministry of Health of the Russian Federation, Moscow, Russian Federation, 2Pediatrics, The Federal State Autonomous Educational Institution of Higher Education The First Moscow State Medical University named after I.M. Sechenov Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation, 3Department of Biostatistics, EOL Labs ltd, Novosibirsk, Rwanda, 4Laboratory of Computational Physics, Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk, Russian Federation, 5Department of Biostatistics, EOL Labs ltd, Novosibirsk, Russian Federation

    Background/Purpose: The range of biological drugs currently used in JIA therapy includes not only anti-TNF but also other varieties. However, despite the high effectiveness and…
  • Abstract Number: 2969 • 2017 ACR/ARHP Annual Meeting

    Efficacy and Safety of Ixekizumab in Patients with Active Psoriatic Arthritis and Previous Inadequate Response to TNF Inhibitors: 52-Week Results from a Phase 3 Study

    Mark C. Genovese1, Bernard Combe2, Joel Kremer3, David Adams4, Chin Lee4, Lisa Kerr4 and Peter Nash5, 1Stanford University Medical Center, Palo Alto, CA, 2Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 3St. Peter's Hospital, Albany, NY, 4Eli Lilly and Company, Indianapolis, IN, 5University of Queensland, Brisbane, Australia

    Background/Purpose: Ixekizumab (IXE) is a high affinity monoclonal antibody that selectively targets interleukin-17A. In patients with active psoriatic arthritis (PsA) who had an inadequate response…
  • Abstract Number: 105 • 2017 ACR/ARHP Annual Meeting

    Tweeting the Meeting: Analysis of Twitter Use during the American College of Rheumatology 2016 Annual Meeting

    Mosaab Mohameden1, Victoria Malkhasyan2, Baker Alkhairi3, Najla Aljaberi4 and Candice Yuvienco5, 1Internal Medicine, University of California San Francisco - Fresno Medical Education Program, Fresno, CA, 2University of California San Francisco - Fresno Medical Education Program, Fresno, CA, 3Internal Medicine, Blake Medical Center, Bradenton, FL, 4Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 5Internal Medicine, Division of Rheumatology Director, University of California San Francisco, Fresno Medical Education Program, Fresno, CA

    Background/Purpose: The American College of Rheumatology (ACR) annual meeting is the premier rheumatology research and education event of the year. The ACR adopted the use…
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