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Session » T Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster

Date: Monday, November 18, 2024

Time: 10:30AM-12:30PM

Meeting: ACR Convergence 2024

10:30AM-12:30PM
Abstract Number: 1855
­Identification of Autoreactive Cytotoxic T Cells in ANCA-Associated Vasculitis
10:30AM-12:30PM
Abstract Number: 1851
Aberrant Tfh Cells Generated by Th17 Cell Plasticity in the Gut Promote Autoimmune Arthritis
10:30AM-12:30PM
Abstract Number: 1837
Baseline Multiome Sequencing of CD45RO+CD45RA-CD4+ T Cell Reveals Distinct Immune Profiles Associated with Subsequent Response to Secukinumab Treatment
10:30AM-12:30PM
Abstract Number: 1861
CD8T Cells Depletion Promotes Human Tph/Tfh Cells Proliferation and Sjogren Syndrome Like Symptoms Without Graft versus Host Diseases in PBMC Transferred-humanized Mice
10:30AM-12:30PM
Abstract Number: 1848
Characterization of Treg Phenotype, Function and Its Transcriptome Signatures in Treatment-naïve Rheumatoid Arthritis
10:30AM-12:30PM
Abstract Number: 1846
Citrullinated Vimentin-reactive Immune-regulatory CD4+CD39+TIGIThi T Cells Expand During Drug Free Remission in HLA-DR Shared-epitope+ ACPA+ Rheumatoid Arthritis
10:30AM-12:30PM
Abstract Number: 1859
Clonal Relationships Between Tph and Tfh Cells in Patients with SLE and in Murine Lupus
10:30AM-12:30PM
Abstract Number: 1858
Co-modification of Citrullinated Proteins with Malondialdehyde-Acetaldehyde Leads to Amplified T Cell Responses and Increased Disease-specific Autoantibody Concentrations
10:30AM-12:30PM
Abstract Number: 1842
Development of Next Generation CAR T Cell Therapy for the Off-the-shelf Treatment of Autoimmune Diseases Without Conditioning Chemotherapy
10:30AM-12:30PM
Abstract Number: 1856
Distinct Proliferative and Special Properties of Peripheral Helper T Cells in RA Synovium
10:30AM-12:30PM
Abstract Number: 1850
Exhausted T-cells Are Increased in Autoimmune Diseases and Predict Response to Anti-TNF in RA and SPA Patients
10:30AM-12:30PM
Abstract Number: 1847
Expression Levels of the ATP-Gated Ion Channel P2RX7 Do Not Predict T Cell Sensitivity to Extracellular ATP and NAD
10:30AM-12:30PM
Abstract Number: 1862
Folate Receptor β CAR-Tregs Induce Monocyte Apoptosis and Immune Polarization: Potential for Therapeutic Application in Rheumatoid Arthritis
10:30AM-12:30PM
Abstract Number: 1835
FoxP3Hi CTLA4+ ICOS+ Regulatory T Cells Are Expanded in Patients with Sarcoidosis but Not Systemic Sclerosis or IgG4-Related Disease
10:30AM-12:30PM
Abstract Number: 1863
Human Endogenous Retroviruses Promote the Aberrant T Cell Differentiation in Systemic Lupus Erythematosus
10:30AM-12:30PM
Abstract Number: 1866
Identification of Sjögren’s Disease-Associated CD4+ T Cell Receptor (TCR) Motifs and Repertoire Landscape Through TCR Deep Sequencing
10:30AM-12:30PM
Abstract Number: 1843
Immune Responses to Herpes Zoster Vaccine Responses in Rheumatic Patients on JAK Inhibitors: Insights in Humoral and Cellular Response
10:30AM-12:30PM
Abstract Number: 1838
M5542: A Potent CD80, CD86, and OX40L Antagonist Fusion Molecule for the Treatment of Autoimmune Diseases
10:30AM-12:30PM
Abstract Number: 1844
Manufacturing of IMPT-514, a CD19/CD20 Bispecific CAR T Cell Product Candidate as a Potential Treatment of Patients with Autoimmune Diseases
10:30AM-12:30PM
Abstract Number: 1853
Mutated Nod2 Enhances Pathogenic Th17 Responses That Promote Experimental Blau Syndrome
10:30AM-12:30PM
Abstract Number: 1839
PPP2R3C Overexpression Suppresses TCR -mediated CD4+ T Cell Abnormal Activation in Systemic Lupus Erythematosus via JNK and AKT-mTOR Pathways
10:30AM-12:30PM
Abstract Number: 1841
Preclinical Evaluation of ALLO-329: Allogeneic CD19 CAR T Cells Expressing an Anti-Rejection CD70 CAR for the Treatment of Autoimmune Diseases
10:30AM-12:30PM
Abstract Number: 1865
Reduction in CD4+T Cell Expression of CD28 and CD2 by Antibody-induced Internalization of CD6: A Potential Step Towards Immune Tolerance
10:30AM-12:30PM
Abstract Number: 1867
RNA Polymerase III Specific CD8+ T Cells at the Interface Between Scleroderma and Cancer
10:30AM-12:30PM
Abstract Number: 1864
S-4321, a Novel Dual-cell Bidirectional PD-1:FcγRIIb Selective Agonist Antibody for the Treatment of Autoimmune Disease
10:30AM-12:30PM
Abstract Number: 1849
Selective Targeting of One-Carbon Metabolism to Combat Rheumatoid Arthritis
10:30AM-12:30PM
Abstract Number: 1840
Synovial Resident Memory T Cell Formation During Inflammation Requires Cell Contact with Fibroblast-Like Synoviocytes
10:30AM-12:30PM
Abstract Number: 1860
Targeting Th1 Effector Cytokines, TNF-α and IFN-γ, Attenuates Experimental Autoimmune Myeloperoxidase ANCA Associated Vasculitis
10:30AM-12:30PM
Abstract Number: 1854
TCR-Nck Modulators: Pioneering Oral Modulation of T Cell Receptor Activation Holding the Promise of Treating Autoimmune Diseases
10:30AM-12:30PM
Abstract Number: 1857
Thymic Mimetic Cells in Humans, Mice and Fish Are Evolutionarily Ancient with Species-specific Adaptations
10:30AM-12:30PM
Abstract Number: 1836
Transcriptional Changes in the Formation of Tissue Resident Memory T Cells in the Joint
10:30AM-12:30PM
Abstract Number: 1845
Treg Expansion and IL-6 Induced STAT3 Phosphorylation in CD4+ T Cells Is a Biomarker of Disease Flare in Rheumatoid Arthritis
10:30AM-12:30PM
Abstract Number: 1852
Uncovering a MAIT-Treg Axis in Skin UV Response: Implications for Photosensitive Reactions in Cutaneous Lupus Erythematosus

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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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