Abstract Number: 1291 • 2019 ACR/ARP Annual Meeting
Semi-Quantitative and Quantitative Evaluation of Magnetic Resonance Imaging in Patients with Idiopathic Inflammatory Myopathies – a Subanalysis of the Prometheus Study
Background/Purpose: Prometheus study was a prospective, randomized, assessor-blind multicenter trial, comparing the efficacy and safety of the glucocorticoid (GC) monotherapy versus combination therapy with methotrexate…Abstract Number: 1310 • 2019 ACR/ARP Annual Meeting
Osteoarthritis: What’s in a Name?
Background/Purpose: The nomenclature of "osteoarthritis" (OA) has been a source of confusion and likely misdiagnosis for centuries. Prior to 1759, most patients with joint diseases…Abstract Number: 1360 • 2019 ACR/ARP Annual Meeting
Ultrasound Guided Synovial Biopsies Safely Aid in the Assessment of Inflammatory Arthritis
Background/Purpose: Synovial biopsies have an important role in the diagnostic evaluation of patients with undifferentiated inflammatory arthritis (UIA) whose clinical examination and blood and synovial…Abstract Number: 1762 • 2019 ACR/ARP Annual Meeting
UV Light Induces Acute Type I Interferon Production in the Skin and Blood Which Is cGAS Dependent
Background/Purpose: Interferon response genes (ISG) are strongly expressed in the skin of many patients with systemic lupus erythematosus (SLE). Since plasmacytoid dendritic cells (pDC) are…Abstract Number: 1768 • 2019 ACR/ARP Annual Meeting
A First-in-class Selective and Potent IRAK4 Degrader Demonstrates Robust in Vitro and in Vivo Inhibition of TLR/IL-1R Activation and Inflammation
Background/Purpose: IL-1R/TLR activation plays a central role in the pathophysiology of multiple autoimmune and inflammatory diseases driven by the IL-1 family of cytokines and by…Abstract Number: 1797 • 2019 ACR/ARP Annual Meeting
Rheumatology Mechanism Madness: A Pilot Collaborative Learning Activity for Rheumatology Trainees
Background/Purpose: The Community of Inquiry (CoI) is a framework to understand how a group of individuals learns together and includes concepts of social, teaching, and…Abstract Number: 1987 • 2019 ACR/ARP Annual Meeting
CCN3 Regulates Macrophage Function in MSU-induced Inflammation
Background/Purpose: Gout is the most common metabolic disease in which monosodium urate (MSU) crystals form and deposit in the joints and soft tissues of patients.…Abstract Number: 2048 • 2019 ACR/ARP Annual Meeting
Opioid Prescription Use Among Patients with Rheumatic Disease: A Population Based Cohort Study
Background/Purpose: Rheumatic diseases can be associated with pain and disability. An international opioid epidemic is ongoing, and prescription opioid use has been linked with increased…Abstract Number: 2061 • 2019 ACR/ARP Annual Meeting
Association of Periodontitis with Rheumatological Disorders: NHANES III Analysis
Background/Purpose: The association between periodontal diseases, smoking, and some systemic diseases such as diabetes mellitusis is well established. Periodontitis and rheumatological disorders share common immunological features and…Abstract Number: 2077 • 2019 ACR/ARP Annual Meeting
Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia and the Fallacy of the Variance Explained
Background/Purpose: In a seminal BMJ paper (Prior 1986), the Tokelau Island migrant study for gout and hyperuricemia concluded preventive strategies to modify body mass, diet…Abstract Number: 2088 • 2019 ACR/ARP Annual Meeting
When It Just Won’t Stop: Chronic Pain and High Impact Chronic Pain Among U.S. Adults with Arthritis
Background/Purpose: Pain is a hallmark of arthritis. Despite growing attention to chronic pain (CP), surprisingly little is known about its magnitude and impact among the…Abstract Number: 2122 • 2019 ACR/ARP Annual Meeting
Outcomes and Risk Factors in Septic Arthritis with Underlying Rheumatic Conditions
Background/Purpose: Septic arthritis is known to cause significant morbidity due to joint destruction and mortality if timely and adequate treatment is not given. In this study,…Abstract Number: 2139 • 2019 ACR/ARP Annual Meeting
Rheumatic Immune-Related Adverse Events Associated with Treatment with Immune Checkpoint Inhibitors: A Multicenter Study of 38 Cases
Background/Purpose: Immune checkpoint inhibitors (ICI) against CTLA-4 or PD- 1/PD-L1 and more recently TIM3, have demonstrated efficacy in improving the survival of patients with diverse…Abstract Number: 2398 • 2019 ACR/ARP Annual Meeting
Prevalence of Anxiety and Depression in a Cohort of Patients with Rheumatic Diseases on Biological Infusions
Background/Purpose: Studies have shown an increased prevalence of psychologic disorders in rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis, compared to…Abstract Number: 2439 • 2019 ACR/ARP Annual Meeting
Cardiovascular Impact of Hyperuricemia in Patients with Psoriatic Arthritis
Background/Purpose: Inflammatory joint diseases (IJD) such as psoriatic arthritis (PsA) have an increased risk of cardiovascular disease (CVD) since inflammation plays a pivotal role in…
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