Abstract Number: 2340 • 2015 ACR/ARHP Annual Meeting
Improvement in Treat to Target Serum Urate Levels: Preliminary Results from a Comparison Between Two Audits of Management
Background/Purpose: 1) assess the current quality of care in gout patients and 2) compare the current management with previous audit data. Methods: a second audit…Abstract Number: 2342 • 2015 ACR/ARHP Annual Meeting
Uric Acid-Lowering Therapy Management Among Rural Veterans Affairs Primary Care Providers
Background/Purpose: ACR guidelines exist for the management of gout including the use of uric acid-lowering therapy. ACR guidelines recommend routine monitoring of uric acid levels…Abstract Number: 2343 • 2015 ACR/ARHP Annual Meeting
Impact of Colchicine Use on the Development of Incident Coronary Artery Disease
Background/Purpose: Patients with gout experience both inflammation and increased risk of cardiovascular disease (CVD). Studies suggest that colchicine reduces myocardial infarction (MI) risk, but whether…Abstract Number: 2347 • 2015 ACR/ARHP Annual Meeting
Can We Predict the Dose of Allopurinol to Achieve Target Urate?
Background/Purpose: Allopurinol is a first line urate lowering therapy in the management of gout. The observation that allopurinol hypersensitivity was associated with allopurinol dose, renal…Abstract Number: 2353 • 2015 ACR/ARHP Annual Meeting
Lesinurad and Febuxostat Combination Therapy: Analysis of Treatment Based on Patient Baseline Renal Function
Background/Purpose: A randomized, double-blind, placebo-controlled, Phase III clinical trial showed that lesinurad, a selective uric acid reabsorption inhibitor (SURI), in combination with febuxostat 80 mg…Abstract Number: 2355 • 2015 ACR/ARHP Annual Meeting
Effects of the Dietary Approaches to Stop Hypertension (DASH) Diet on Serum Uric Acid Levels: A Randomized Controlled Trial
Background/Purpose: There is a remarkable, increasing disease burden of gout and its associated cardiovascular-metabolic comorbidities (e.g., hypertension in 74% of cases in the US), underscoring…Abstract Number: 2400 • 2015 ACR/ARHP Annual Meeting
Association Between Serum Urate and Osteoarthritis Progression in a Non-Obese Cohort
Background/Purpose: We recently reported an association between gout and osteoarthritis (OA) presence and severity, and a possible association between hyperuricemia and OA severity (Howard et…Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting
Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties
Background/Purpose: Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…Abstract Number: 2511 • 2015 ACR/ARHP Annual Meeting
Primary Care Management of Patients with Rheumatic Diseases Prior to Rheumatologist Consultation
Background/Purpose: Primary care physicians (PCP) often play a central role in the early detection and referral for patients with rheumatic diseases. Our aim was to…Abstract Number: 2791 • 2015 ACR/ARHP Annual Meeting
TREX-1 Variants in Sjögren’s Syndrome Related Lymphomagenesis
Background/Purpose: Three prime Repair Exonuclease 1 (TREX-1) is an exonuclease involved in DNA repair preventing genomic instability. TREX-1 variants have been previously associated with activation of type…Abstract Number: 2815 • 2015 ACR/ARHP Annual Meeting
A Comparison of Th17 Gene Expression in Psoriatic Arthritis Synovial Fluid and Peripheral Blood
Background/Purpose: Psoriatic arthritis (PsA) is a destructive inflammatory arthritis that develops in approximately 30% of patients with cutaneous psoriasis. Th17 cells infiltrate psoriatic skin and…Abstract Number: 2827 • 2015 ACR/ARHP Annual Meeting
Analysis of HLA-B27 Transgenic Rats Reveals Specific Gut Transcriptome and Microbiome Signatures Associated with Inflammation
Background/Purpose: HLA-B27 and human beta 2-microglobulin expression in rats (transgenic; TG) induces a spontaneous inflammatory disease resembling human spondyloarthritis (SpA) with associated gastrointestinal inflammation. While…Abstract Number: 2834 • 2015 ACR/ARHP Annual Meeting
CXCL10 Expression Is Elevated in Synovial Fluid of Psoriatic Arthritis Patients
Background/Purpose: Psoriatic arthritis (PsA), an inflammatory musculoskeletal disease, develops in approximately 30% of patients with psoriasis. We previously identified C-X-C motif chemokine 10 (CXCL10) as…Abstract Number: 3164 • 2015 ACR/ARHP Annual Meeting
Calcium Pyrophosphate Deposition Disease and Associated Medical Co-Morbidities in the Veteran Population
Title: Calcium Pyrophosphate Deposition Disease and Associated Medical Co-Morbidities in the Veteran Population. Background/Purpose: Precipitation of calcium pyrophosphate dihydrate (CPP) crystals in articular tissues…Abstract Number: 2881 • 2014 ACR/ARHP Annual Meeting
The Center of Excellence in Musculoskeletal Care and Education: A Sustainable Interprofessional, Multidisciplinary Programmatic Innovation Developed with the Department of Veterans Affairs
Background/Purpose While musculoskeletal (MSK) problems are common in primary care, the current formal education in the evaluation and management of these conditions is inadequate. Through…
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