Abstract Number: 1858 • 2017 ACR/ARHP Annual Meeting
Utilizing Needs Assessment Data to Establish Foundational Training for Adult and Pediatric Nurse Practitioners (NP) and Physician Assistants (PA) Entering Rheumatology Practice
Background/Purpose: Rheumatology is a cognitive specialty requiring years of clinical exposure and hands-on training to manage complex patients. However, there is no current standardized training…Abstract Number: 1913 • 2017 ACR/ARHP Annual Meeting
Inter-Omic Analysis Reveals Functional Relationship between Diverse Gut Microbiota and Dysregulated Host Immune Response in HLA-B27-Mediated Experimental Spondyloarthritis
Background/Purpose: HLA-B27 has been hypothesized to alter gut microbiota and host-microbe interactions to promote spondyloarthritis (SpA). In HLA-B27 transgenic (HLA-B27 Tg) rats with experimental SpA,…Abstract Number: 1955 • 2017 ACR/ARHP Annual Meeting
Health Care Provider Advice for Weight Loss Among US Adults with Arthritis, National Health Interview Survey, 2014
Background/Purpose: Most clinical practice guidelines for the management of osteoarthritis recommend weight loss for adults with arthritis who are overweight or obese. A health care…Abstract Number: 2050 • 2017 ACR/ARHP Annual Meeting
Analysis of Data Collected from Right and Left Limbs: Accounting for Dependence and Improving Statistical Efficiency in Musculoskeletal Research
Background/Purpose: Statistical techniques used in musculoskeletal research often inefficiently account for paired-limb measurements or the relationship between measurements taken from multiple sites within limbs. This…Abstract Number: 2053 • 2017 ACR/ARHP Annual Meeting
Computed Tomography Dependent Diagnosis of Crowned Dens Syndrome; A Cervical Manifestation of Patients with Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
Background/Purpose: Crowned Dens Syndrome (CDS), a variation of Calcium Pyrophosphate Deposition Disease (CPPD), is a radiologic-clinical entity defined by the association of radiological calcifications around…Abstract Number: 2057 • 2017 ACR/ARHP Annual Meeting
Identification of Urate Deposits in Patients with Asymptomatic Hyperuricemia Using a Dual-Energy CT Scan
Background/Purpose: Serum uric acid (sUA) is a useful indicator of the risk of developing gout. However, most patients with elevated sUA levels do not have…Abstract Number: 2061 • 2017 ACR/ARHP Annual Meeting
Population-Specific Factors Associated with Fractional Excretion of Uric Acid
Background/Purpose: For most people with gout, reduced renal clearance of uric acid is a key contributor to hyperuricemia. It is increasingly recognized that gout has…Abstract Number: 2071 • 2017 ACR/ARHP Annual Meeting
A Novel Selective URAT1 Inhibitor, Tei-a, with Potent Uricosuric Property
Background/Purpose: Hyperuricemia, abnormally elevated level of serum uric acid, is associated with gout as well as other diseases including metabolic syndrome, hypertension, diabetic kidney disease.…Abstract Number: 2072 • 2017 ACR/ARHP Annual Meeting
A Pharmacokinetic and Pharmacodynamic Evaluation of URC102, a Potent and Selective Inhibitor of URAT1, after Single and Multiple Oral Administrations in Healthy Volunteers
Background/Purpose: URC102, a novel and potent inhibitor of human uric acid transporter 1 (hURAT1), is currently under clinical development to treat patients with gout. In…Abstract Number: 2078 • 2017 ACR/ARHP Annual Meeting
Hypersensitivity Reactions with Allopurinol and Febuxostat in Adults 65 Years or Older: A Study Using the Medicare Claims Data
Background/Purpose: Clinicians using allopurinol are always concerned about the risk of rare hypersensitivity reaction. Allopurinol and febuxostat are the two most common urate-lowering agents used…Abstract Number: 2080 • 2017 ACR/ARHP Annual Meeting
Serum Uric Acid and Incident Dementia: A Population Based Study
Background/Purpose: Elevated serum uric acid (sUA) is an established risk factor for gout. Its role in the development of dementia is controversial, low levels of…Abstract Number: 2081 • 2017 ACR/ARHP Annual Meeting
Synovial Fluid Leukocyte Count and Its Association with Crystal Deposition in Asymptomatic Hyperuricemia
Background/Purpose: Articular and periarticular deposits of monosodium urate (MSU) crystals in asymptomatic hyperuricemia (AH) may associate with more severe forms of atherosclerosis [Andrés 2016]. This…Abstract Number: 2088 • 2017 ACR/ARHP Annual Meeting
Clinical Significance of Urate Deposition in Tendon: A Dual-Energy CT Study
Background/Purpose: Dual-energy computed tomography (DECT) is advanced imaging modality that shows the deposition of monosodium urate (MSU) crystal in tissue as a color signal. In…Abstract Number: 2089 • 2017 ACR/ARHP Annual Meeting
Arhalofenate Acid Inhibits Urate Crystal-Induced Inflammatory Responses through Activation of AMP-Activated Protein Kinase (AMPK) Signaling
Background/Purpose: Arhalofenate is an investigational drug with dual uricosuric and anti-inflammatory properties. Arhalofenate reduced the risk of acute flare while lowering serum urate levels in…Abstract Number: 2090 • 2017 ACR/ARHP Annual Meeting
Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with Veterans Affairs Medical Center
Background/Purpose: Anakinra is an IL-1 blocking medication used off label to relieve acute inflammation from gout and pseudogout. The efficacy and safety of this treatment…
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