2013 ACR/ARHP Annual Meeting Archives

Abstract Number: 1976

Magnetic Resonance Imaging-Assessment Of Early Response To Certolizumab Pegol In Rheumatoid Arthritis: A Randomized, Double-Blind, Placebo-Controlled Phase IIIb Study Applying Magnetic Resonance Imaging At Week 0, 1, 2, 4, 8 and 16
Abstract Number: 302

Maintenance Of Efficacy and Safety Of Ustekinumab In Patients With Active Psoriatic Arthritis Despite Prior Conventional Nonbiologic and Anti-TNF Biologic Therapy: 1‑year Results Of a Phase 3, Multicenter, Double-Blind, Placebo-Controlled Trial
Abstract Number: 1570

Maintenance Therapy With Taclorimus and Mizoribine Pulse In SLE
Abstract Number: 750

Maintenance Treatment In Childhood Granulomatosis With Polyangiitis
Abstract Number: 195

Major Cost Savings Associated With Reduced Biologic Dosing Frequency In Inflammatory Arthritis
Abstract Number: 327

Major Differences In The Pattern Of Joint Swelling and Tenderness In a Large Psoriatic Arthritis Cohort – Results From An Exploratory Hierarchical Cluster Analysis
Abstract Number: 1879

Major Histocompatibility Complex Class I Molecules Contribute To Behçet’s Disease Risk Through Both Innate and Adaptive Immune Interactions
Abstract Number: 2504

Male Children With Higher SLE Disease Activity In An US Cohort
Abstract Number: 719

Mammalian Target Of Rapamycin (mTOR) Skews T Cell Lineage Development In Systemic Lupus Erythematosus (SLE)
Abstract Number: 362

Management Of Hyperlipidemia In Patients With RA: Results From The Corrona Certain Study
Abstract Number: 2807

Management Of Vertebral Osteomyelitis: A Randomized Clinical Trial Comparing 6 Versus 12 Weeks Of Antibiotic Treatment
Abstract Number: 861

Many Gout Patients Treated By Rheumatologists Do Not Meet Established Treatment Goals Despite Long-Term Urate Lowering Therapy: Results Of a Gout Patient Encounter Survey
Abstract Number: 1025

Mapping The Health Assessment Questionnaire On a Preference Based Utility Measure In a Large Canadian Rheumatoid Arthritis Cohort: Results From The Ontario Best Practices Research Initiative
Abstract Number: 1704

Mapping The Shared and Distinct HLA Alleles For Seropositive and Seronegative Rheumatoid Arthritis
Abstract Number: 269

Marked Improvement In Patient Reported Outcomes Of Children With Active Systemic Juvenile Idiopathic Arthritis With Canakinumab Treatment – Results Of The Phase III Program
Abstract Number: 2892

Masp-1/3 Deficient MRL/Lpr Mice Lack The Alternative Complement Pathway Activation and Are Protected From Development Of Lupus-Like Glomerulonephritis
Abstract Number: 1900

Mass Spectrometry-Based Salivary Proteomics For The Discovery Of Novel Diagnostic Biomarkers For Primary Sjögren’s Syndrome and Its Clinical Subsets
Abstract Number: 2500

Mast Cells Are a Major Source Of IL-17 In Synovium and Extra-Articular Tissues In Spondyloarthritis Related Diseases
Abstract Number: 2834

Maternal data Analysis Of The French Registry Of 205 Cases Of Immune Congenital Heart Block (neonatal lupus)
Abstract Number: 1274

Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus
Abstract Number: 1331

Mathematical Model To Predict The Early Responders In a Monocentric Cohort Of Patients With Rheumatoid Arthritis Treated By Anti TNF-Alpha
Abstract Number: 1677

May Giant Cell Arteritis Be Characterized By Different Clinical Entity and Long-Term Outcome?
Abstract Number: 1525

Measurement Of Lateral Spinal Flexion and Schober Is Sufficient To Be Informed About Spinal Mobility In Patients With Ankylosing Spondylitis: 12-Year OASIS Results
Abstract Number: 1003

Measuring Economic Value of Morning Stiffness; Consistency Over 1 Year
Abstract Number: 2122

Mechanical Back Pain Demonstrates Better Response To Celecoxib Than Acetaminophen Despite Lack Of MRI-Defined Inflammatory Changes In The Spine
Abstract Number: 1295

Mechanisms For Fostamatinib-Induced Blood Pressure Elevation
Abstract Number: 974

Medical Student Perceptions Of Point-Of-Care Ultrasound In Musculoskeletal Education
Abstract Number: 2678

Medically Significant Infections Are Increased In Patients With Juvenile Idiopathic Arthritis Treated With Etanercept. Results From The British Society For Paediatric and Adolescent Rheumatology Etanercept Cohort Study
Abstract Number: 2849

Medication Adherence and Healthcare Costs Among Patients With Fibromyalgia: Combination Medication Versus Duloxetine, Pregabalin, and Milnacipran Initiators
Abstract Number: 210

Medication Adherence In Patients With Gout: A Systematic Review
Abstract Number: 105

Medication Use With Denosumab (Prolia^®) In a Large Claims Database In The United States
Abstract Number: 1519

Meeting The ACR 2010 Fibromyalgia Criteria Worsens Disease Activity and Quality Of Life In Patients With Axial Spondyloarthritis Treated With Infliximab
Abstract Number: 536

Membrane-Bound TNF Drives Axial and Peripheral Inflammation and Pathologic New Bone Formation
Abstract Number: 235

Meniscal Extrusion Is a Better Predictor Of Radiographic Osteoarthritis Change Over Ten Years Compared To Cartilage Volume Loss
Abstract Number: 373

Menopause Occurs Earlier and Is An Independent Risk Factor For Osteoporosis In Women With Rheumatoid Arthritis
Abstract Number: 718

Mesenchymal Stem Cells and Skin Fibroblasts Both Suppress Early Steps In T Cell Activation In a Nitric-Oxide Dependent Manner
Abstract Number: 89

Meta-Analysis of Randomized Controlled Trials Assessing the Effects of Vitamin D Supplementation On Skeletal Muscle Strength
Abstract Number: 2875

Metabolic Profiles of Synovial Fibroblasts
Abstract Number: 2757

Metabolomics For The Identification Of Urinary Biomarkers In Knee Osteoarthritis Progression
Abstract Number: 1332

Metaflammation, PEDF and Chemerin: Potential Systemic Factors Which Link Obesity To Response To Therapy In Early Rheumatoid Arthritis
Abstract Number: 1018

Methodology Of Determining An Appropriate Look-Back Period To Identify Autoimmune Rheumatic Disease In a Study Of Post-Myocardial Infarction Mortality
Abstract Number: 2181

Methotrexate and Infliximab With Or Without Zoledronic Acid Improve Disease Activity and Prevent Damage Progression In Chronic Nonbacterial Osteomyelitis
Abstract Number: 2688

Methotrexate Dose Has Minimal Effects On Methotrexate-Related Toxicity In Patients With Early Rheumatoid Arthritis Treated In Combination With Adalimumab – Results Of Concerto Trial
Abstract Number: 797

Methotrexate Exposure Assessment In Routine Clinical Rheumatology Practice: Effect Of Dosing and Route Of Administration On Polyglutamate Levels
Abstract Number: 1317

Methotrexate Optimization (ie introduction during the first 3 months and with dose escalation at 6 months at least at 20mg/w or 0.3mg/kg/w) Is Associated With Better Clinical Outcomes In Daily Practice: Results From The Espoir Cohort
Abstract Number: 792

Methotrexate Polyglutamates in Erythrocytes Are Associated With Lower Disease Activity in Juvenile Idiopathic Arthritis Patients
Abstract Number: 1640

Methotrexate Treatment Affects Effector, But Not Regulatory T Cells in Juvenile Idiopathic Arthritis
Abstract Number: 482

Methotrexate Use At Infliximab Initiation and Impact On Treatment Outcomes: An Analysis From A Canadian Registry
Abstract Number: 1108

Methylphenidate Improves Concentration, Energy and Mood In Fibromyalgia
Abstract Number: 2039

Micro and Nanoparticles As Possible Causative-Prognostic Co-Factors Of Mixed Cryoglobulinemia Syndrome
Abstract Number: 148

Microarray Analysis Of Synovial Specimen of Early Human (CHECK) and Experimental Osteoarthritis to Identify Pathways and Processes Associated with Pathology
Abstract Number: 875

Microrna Expression Profiles Associated With Response To Adalimumab and Methotrexate Versus Methotrexate: A Placebo-Controlled Clinical Trial
Abstract Number: 1161

Microrna-155 As a Proinflammatory Regulator via SHIP-1 Down-Regulation In Acute Gouty Arthritis
Abstract Number: 2738

Microrna-Mediated Regulation Explains Allelic Risk Of TLR7 Variant Predisposing To Systemic Lupus Erythematosis
Abstract Number: 2595

Microvascular Abnormalities In Patients With Early Systemic Sclerosis: Less Severe Morphological Changes Compared To Patients With Definite Disease
Abstract Number: 2277

Midcarpal Joint Effusion Is As Common As Radiocarpal Joint Effusion In Swollen Wrists Of Patients With Rheumatoid Arthritis
Abstract Number: 2643

Midkine Is a Novel Prognostic Factor In Patients With Vasculitis Syndrome
Abstract Number: 130

Mindfulness Is Associated With Psychological Symptoms, Self-Efficacy and Quality Of Life Among Patients With Fibromyalgia
Abstract Number: 688

Minimal Clinically Important Investigations In Systemic Sclerosis
Abstract Number: 944

Mir-125a: A Novel Regulator Of IL-6 and TLR Driven Pathways In RA Pathogenesis
Abstract Number: 2860

Mir-26a, Mir-30b and HER2: New Players On Lupus Nephritis Pathogenesis
Abstract Number: 2423

Mir-27b As Biomarker and Regulator Of IL-6R Pathway In Resistant Rheumatoid Arthritis Monocyte
Abstract Number: 941

Mir-34a In Rheumatoid Arthritis: Characterisation Of Elevated Synovial Expression and Association With Treatment Resistance
Abstract Number: 1846

Mitochondrial Dysfunction Induces An Inflammatory, Tissue-Degrading, and Angiogenic Response In Normal Human Synoviocytes
Abstract Number: 1316

MMP3 As a Predictor Identifying a Subgroup Of Rheumatoid Patients Who Are Successfully Treated With Methotrexate (MTX) Alone But Still Subject To Radiographic Progression
Abstract Number: 1419

Mode Of Action Change Not Necessary After Failing The First Tumornecrosisfactor Inhibitor: Preliminary Results Of a Randomized Controlled Trial
Abstract Number: 1204

Model-Based Pharmacokinetics Of Canakinumab and Pharmacodynamics Of IL-1Beta Binding In Cryopyrin Associated Periodic Syndromes, a Step Towards Personalized Medicine
Abstract Number: 1024

Modeling The Benefit Risk Profiles Of a New Janus Kinase Inhibitor Tofacitinib Compared Tottumour Necrosis Factor Inhibitor Biologic Treatments Incorporating Conjoint Derived Patient Preference Weights
Abstract Number: 1931

Models Of Care For Arthritis: Drivers, Facilitators and Barriers To Their Development and Implementation
Abstract Number: 2601

Modified Rodnan Ultrasound Skin Score: An Ultrasound Skin Scoring Approach In Systemic Sclerosis
Abstract Number: 147

Modular Analysis Of In Peripheral Blood Gene Expression In Rheumatoid Arthritis Captures Reproducible Gene Expression Changes In TNF Responders
Abstract Number: 2563

Modulating Myofibroblast Transition Of Human Scleroderma Fibroblasts Through Inhibition Of Rho Guanine Nucleotidase-Regulated Gene Transcription
Abstract Number: 1172

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
Abstract Number: 2702

Molecular Pathogenesis and Genetics Of Tartrate-Resistant Acid Phosphatase Deficiency In Systemic Lupus Erythematosus
Abstract Number: 2223

Monitoring Of Active Matrix Metalloproteinase-3 Using
Abstract Number: 576

Monitoring Of Opportunistic Virus Infections In Systemic Lupus Erythematosus
Abstract Number: 1223

Monitoring Osteoporosis Therapy: Can FRAX Help To Assess Success Or Failure In Achieving Treatment Goals?
Abstract Number: 2784

Mononeuritis Multiplex Predicts The Need For Immunosuppressive Or Immunomodulatory Drugs For Eosinophilic Granulomatosis With Polyangiitis, Polyarteritis Nodosa and Microscopic Polyangiitis Patients Without Poor-Prognosis Factors
Abstract Number: 858

Monosodium Urate Crystal Induced Macrophage Inflammation Is Attenuated By Chondroitin Sulfate: Pre-Clinical Model For Gout Prophylaxis?
Abstract Number: 1134

More Evidence For Breaking The ‘law Of valgus’: Imaging Evidence For Higher Prevalence and Volume Of Bone Marrow Lesions In The Medial Patellofemoral Joint
Abstract Number: 1185

More Than One-Third Of Patients Reach Serum Urate Target and Continue To Report Multiple Flares
Abstract Number: 2673

Mortality In Clinically Relevant Osteoarthritis and Rheumatoid Arthritis Compared With The General Population
Abstract Number: 2295

Mortality In Early Rheumatoid Arthritis Comparing Lithuania and Finland. A 13-Year Follow Up
Abstract Number: 2059

Mortality In Polymyositis and Dermatomyositis: A Single Centre Study
Abstract Number: 2778

Mortality In United States Veterans With The HLA-B27 Gene
Abstract Number: 2033

Mortality Prognostic Factors Of Patients With Systemic Autoimmune Diseases Admitted To An Intensive Care Unit
Abstract Number: 781

Mortality Rates, Readmissions and Revascularisation Following a First Myocardial Infarction In Patients With Autoimmune Rheumatic Disease Compared With Controls
Abstract Number: 2917

Mortality, Recurrence, and Hospital Course of Patients With Systemic Sclerosis Related Acute Intestinal Pseudo-Obstruction
Abstract Number: 2261

Motivations For Inadequate Persistence With Disease Modifying Anti-Rheumatic Drugs In Early Rheumatoid Arthritis: The Patient’s Perspective
Abstract Number: 2663

Moving Towards Personalized Healthcare: A Patient Reported Outcome Based Algorithm Can Aid Rheumatologists and Patients In Monitoring Rheumatoid Arthritis In Daily Clinical Practice
Abstract Number: 1136

MR T1ρ and T2 Of Meniscus After Acute Anterior Cruciate Ligament Injuries
Abstract Number: 288

MRI Findings In Juvenile Spondyloarthopathy and Effects Of Treatment On Subsequent MRI
Abstract Number: 2511

Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification
Abstract Number: 510

Multicentric Analysis Of Inter and Intra Observer Reliabilities For Histopathological Abnormalities In Salivary Gland Biopsy In Primary Sjögren Syndrome
Abstract Number: 635

Multiple Altered Soluble Inflammatory Mediators Correlate With Disease Activity and Mark Impending Disease Flare In European-American Lupus Patients
Abstract Number: 1459

Multiple Cytokine Profiling Predicts The Effectiveness Of Switching Biologics In Rheumatoid Arthritis
Abstract Number: 1388

Multiplex Cytokine Analyses In Patients With Rheumatoid Arthritis Require Use Of Agents Blocking Heterophilic Antibody Activity
Abstract Number: 2561

Multiplex Cytokine Analysis Of Dermal Interstitial Blister Fluid In Systemic Sclerosis Defines Potential Pathogenic Pathways and Differentiates Clinical Subsets
Abstract Number: 88

Musculoskeletal Diseases Have The Worst Impact On Physical Health Compared With Other Diseases – Results Of The Dutch cross-Sectional Study
Abstract Number: 1043

Musculoskeletal Hospital Admissions Among Patients Treated For Rheumatoid Arthritis Between 1999 and 2010 Compared With The General Population In The Netherlands
Abstract Number: 2135

Musculoskeletal Pain Explains Differences In Function At Time Of Surgery In Black TKR and THR Patients
Abstract Number: 604

Mycophenolate Mofetil Is Not Associated With Reduced Cardiovascular Or Lupus Damage Accumulation In a Cross-Sectional Lupus Cohort Study
Abstract Number: 955

Myeloid Deletion Of SIRT1 Aggravates Serum Transfer Arthritis But Ameliorate Collagen-Induced Arthritis
Abstract Number: 100

Myocardial Infarction and Mortality after Joint Surgery in Patients with Rheumatoid Arthritis Compared with the General Population