Session Type: ACR Poster Session C
Session Time: 9:00AM-11:00AM
Background/Purpose: Previously, Early Systemic Sclerosis (Early-SSc) patients were defined as patients with Raynaud phenomenon (RP) and either a scleroderma marker autoantibody or typical capillaroscopy abnormalities or both. Since 2013 the definition of Early-SSc has been updated: Patients should not meet the new 2013 ACR/EULAR criteria for the classification of Systemic Sclerosis (SSc). EUSTAR group also proposed preliminary criteria for the very early diagnosis of SSc which have not yet been validated. Our aim was to revise the usefulness of Le Roy criteria and Very Early EUSTAR criteria in identifying patients at risk of development of SSc.
Methods: Retrospective study of a wide and unselected series of patients with Early-SSc and SSc from a single university hospital from June 2012 to August 2015. We excluded patients who fulfilled 2013 ACR/EULAR criteria at first visit. Patients were classified as Early-SSc following Le Roy criteria and classified as SSc according to the 2013 ACR/EULAR criteria during follow-up. We reviewed EUSTAR criteria in both groups.
Conclusion: In our study, over the half of the patients initially classified as Early-SSc progressed to SSc during follow-up. EUSTAR preliminary criteria were more frequent in patients who during follow-up fulfilled 2013 ACR/EULAR criteria for SSc, although only the positivity of ANA was statistically significant. Further studies are needed to better characterize the patients with Early-SSc and Very Early-SSc.
To cite this abstract in AMA style:Ortiz-Sanjuán FM, Ivorra Cortes J, Gonzalez Puig L, Chalmeta Verdejo I, Grau Garcia E, Feced Olmos C, Labrador Sanchez E, Arevalo Ruales K, Negueroles Albuixech R, Fragio Gil J, Martinez Cordellat I, Valero Sanz JL, Alcañiz Escandell C, Najera Herranz C, Poveda Marin G, Roman JA. Usefulness of the Eustar Preliminary Criteria for Vey Early Systemic Sclerosis and Le Roy Criteria for Early-Systemic Sclerosis in Identifying Patients at Risk of Development of Systemic Sclerosis [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/usefulness-of-the-eustar-preliminary-criteria-for-vey-early-systemic-sclerosis-and-le-roy-criteria-for-early-systemic-sclerosis-in-identifying-patients-at-risk-of-development-of-systemic-sclerosis/. Accessed April 7, 2020.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/usefulness-of-the-eustar-preliminary-criteria-for-vey-early-systemic-sclerosis-and-le-roy-criteria-for-early-systemic-sclerosis-in-identifying-patients-at-risk-of-development-of-systemic-sclerosis/