Background/Purpose: To assess the correlation of disease activity, functional and metrological status and quality of life with sleep quality and balance status in AS.
Methods: Subjects with Ankylosing Spondylitis (AS) according to Modified New York criteria were recruited into the study. Disease activity was assessed with BASDAI. Functional status (BASFI), quality of life (ASQoL) and metrological score (BASMI) were assessed. Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), Leeds Assessment Scale of Handicap (Leeds Scale) were managed. Berg Balance Scale, Tinetti Balance Assessment Tool and VAS-fear of falling were used to asses patients’ balance.
Results: Forty two AS patients (36 male) with mean age 38,38 (SD=11,28) years were recruited. The disease duration was 139,06 (SD=100,37) months. There were significant correlations between BASDAI and Beck Depression Inventory (p=0,01), Pittsburgh Sleep Quality Index (p=0,01). BASDAI scores were not correlated with Tinetti Balance Assessment Tool (p=0,107) , VAS-Fear of Falling (p=0,111), Leeds Scale (p=0,072) and Berg Balance Scale (p=0,164). BASFI had significant correlations with Beck Depression Inventory (p=0,01), Pittsburg Sleep Quality Index (p<0,001), Tinetti Balance Assessment Tool (p=0,028), Leeds Scale (p<0,001) and Berg Balance Scale (p=0,001). BASMI had significant correlation with Beck Depression Inventory (p=0,007), VAS-fear of falling (p=0,011), Leeds Scale (p=0,005) and Berg Balance Scale (p<0,001). BASMI was not correlated with Pittsburg Sleep Quality Index (p= 0,124) and Tinetti Balance Assessment Tool (p=0,342). ASQoL had significant correlation with Beck Depression Inventory (p<0,001), Pittsburgh Sleep Quality Index (p= 0,005), Tinetti Balance Assessment Tool (p= 0,042), Leeds Scale (p=0,001) and Berg Balance Scale (p=0,023).
Conclusion: Although disease activity had good correlation with depression and sleep disturbances it had not significant correlation with patients’ balance status. The functional level which shows disease severity had significant correlation with sleep disturbances and balance status in AS. Quality of life was worse in patients with sleep disturbance and low balance status.
Disclosure:
M. T. Duruoz,
None;
Z. Sari Surmeli,
None;
E. Topcu,
None.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/the-correlation-of-disease-activity-functional-status-and-quality-of-life-with-sleep-disturbance-and-balance-status-in-ankylosing-spondylitis-as/