ACR Meeting Abstracts

ACR Meeting Abstracts

  • Home
  • Meetings Archive
    • 2019 ACR/ARP Annual Meeting
    • 2018 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP Annual Meeting
    • 2017 ACR/ARHP PRSYM
    • 2016 ACR/ARHP Annual Meeting
    • 2015 ACR/ARHP Annual Meeting
    • 2014 ACR/ARHP Annual Meeting
    • 2013 ACR/ARHP Annual Meeting
    • 2012 ACR/ARHP Annual Meeting
    • 2011 ACR/ARHP Annual Meeting
    • 2010 ACR/ARHP Annual Meeting
    • 2009 ACR/ARHP Annual Meeting
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • Register
    • View and print all favorites
    • Clear all your favorites
  • Meeting Resource Center

Abstract Number: 2944

Sedentary Time Is an Independent Risk Factor for Disability Onset Among Adults at Elevated Risk: Prospective Cohort Study

Jungwha Lee1, Jing Song2, Barbara Ainsworth3, Rowland W. Chang4, Linda S. Ehrlich-Jones5, Christine Pellegrini6, Pamela Semanik7, Dorothy D. Dunlop2 and Leena Sharma8, 1Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Arizona State University, Pheonix, AZ, 4Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Rehabilitation Institute of Chicago, Chicago, IL, 6Center for Behavioral Health, Northwestern University Feinberg School of Medicine, Chicago, IL, 7Rush University, Chicago, IL, 8Northwestern University, Chicago, IL

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: Disability, Knee, Osteoarthritis and physical activity

  • Tweet
  • Email
  • Print
Save to PDF
Session Information

Session Title: Epidemiology/Public Health

Session Type: Abstract Submissions (ARHP)

Background/Purpose:  Disability threatens personal independence and is a major driver of health care costs. Physical activity has been shown to prevent disability.  Sedentary behavior, already associated with poor health outcomes, may have a unique relationship to the development of disability or simply reflect limited recommended moderate/vigorous physical activity (MVPA).  If a separate and distinct risk factor, reducing sedentary behavior may provide an additional strategy to reduce disability among older adults. 

Methods: Prospective multi-site cohort of 1680 community dwelling adults aged 49 years or older were at elevated risk to develop disability due to knee osteoarthritis or having knee osteoarthritis risk factors.  Baseline sedentary and non-sedentary (e.g., light, moderate, vigorous) time were objectively measured using accelerometers.  Participants were classified into sedentary time quartiles groups. Disability was ascertained from limitations in instrumental and basic activity of daily living (IADL/ADL) at baseline and two years.  Hazard ratios for disability onset over 2 years follow-up were estimated from discrete time proportional hazards model controlling MVPA time, socioeconomic factors (age, sex, race/ethnicity, education, income), health factors (function, comorbidity, Center for Epidemiological Studies Depression score, body mass index category, current smoking, knee pain, knee OA severity, knee symptoms, knee injury, other lower extremity joint pain, gait speed).  

Results: Incident disability was 147 versus 69, 62, and 72 per 1000 person-years over 2-years follow-up in the most sedentary quartile group (>11.5 sedentary hours per day) compared to the three less sedentary quartile groups, irrespectively. Less sedentary time was significantly associated with decreased risk of incident disability independent of moderate/vigorous minutes and other covariates (hazard ratios comparing three less sedentary quartiles vs. the most sedentary quartile, 0.62, 0.52, 0.57, irrespectively) (Figure). The average of the three less sedentary quartiles compared to the most sedentary quartile was associated with 44% decreased risk of disability (HR=0.56 [95% CI, 0.37-0.81], P=0.003). From further analyses using an isotemporal model, replacing one hour sedentary time with one hour light activity (e.g. walking) was associated with 51% decreased risk of disability onset for those in the most sedentary quartile group, independent of potential confounders and time spent in other activities (HR=0.49 [95% CI, 0.29-0.85], P=0.01; not shown in Figure).

Conclusion:  Sedentary time appears to be a separate and distinct risk factor for incident disability among adults at elevated risk for disability. In addition to increasing MVPA physical activity, these findings suggest decreasing sedentary time may be an additional strategy to prevent disability onset.


Disclosure:

J. Lee,
None;

J. Song,
None;

B. Ainsworth,
None;

R. W. Chang,
None;

L. S. Ehrlich-Jones,
None;

C. Pellegrini,
None;

P. Semanik,
None;

D. D. Dunlop,
None;

L. Sharma,
None.

  • Tweet
  • Email
  • Print
Save to PDF

« Back to 2014 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/sedentary-time-is-an-independent-risk-factor-for-disability-onset-among-adults-at-elevated-risk-prospective-cohort-study/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

Annual Meeting in Atlanta, Georgia

© COPYRIGHT 2019 AMERICAN COLLEGE OF RHEUMATOLOGY

Wiley

  • Home
  • Meetings Archive
  • Advanced Search
  • Meeting Resource Center
  • Online Journal
  • Privacy Policy
  • Permissions Policies
loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.