ACR Meeting Abstracts

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  • Abstract Number: 475 • 2019 ACR/ARP Annual Meeting

    Myopenia in Elderly Female Patients with Rheumatoid Arthritis Is Associated with Severe Joint Damage: A Cross-sectional Study

    Chu-Tao Chen 1, Jian-Zi Lin 1, Jian-Da Ma 1, Li-Juan Yang 1, Qian-Hua Li 1, Le-Feng Chen 1, Ying-Qian Mo 1 and Lie Dai1, 1Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China (People's Republic)

    Background/Purpose: Our previous study reported myopenia is associated with joint damage in rheumatoid arthritis (RA). However, little is known about body composition (BC) disorder in…
  • Abstract Number: 476 • 2019 ACR/ARP Annual Meeting

    Decreased Muscle Mass, a Novel Predicting Indicator for One-year Radiographic Progression in Rheumatoid Arthritis: A Real-world Cohort Study

    Jian-Zi Lin 1, Jian-Da Ma 1, Qian-Hua Li 1, Ying-Qian Mo 1, Li-Juan Yang 1, Le-Feng Chen 1, Chu-Tao Chen 1, Jun-Wei Wang 1, Dong-Hui Zheng 1 and Lie Dai1, 1Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China (People's Republic)

    Background/Purpose: Obesity paradox based on body mass index (BMI) in rheumatoid arthritis (RA) remain elusive. Our previous cross-sectional study has reported myopenia is associated with joint…
  • Abstract Number: 477 • 2019 ACR/ARP Annual Meeting

    Inflammation but Also Pain and Function, and Psychological Impact Is Related to Non-Acceptable Status in Patients with Rheumatoid Arthritis: A Factorial Analysis in 643 Patients

    Catia Duarte1, Eduardo Santos 2, Eirik Kristianslund 3, Turid Heiberg 4, Maarten de Wit 5, Maxime Dougados 6, Tore Kvien 7, Laure Gossec 8 and Jose Pereira da Silva 9, 1Department of Rheumatology, Centro Hospitalar Universitario de Coimbra, Coimbra, Coimbra, Portugal, 2Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Oslo, Norway, 4Department for Research and Education, Oslo University Hospital, Oslo, Norway, 5Department of Medical Humanities, Amsterdam Public Health (APH), Amsterdam University Medical Centre, Amsterdam, Netherlands, 6Cochin Hospital, Paris, France, 7Diakonhjemmet Hospital, Dept. of Rheumatology / University of Oslo, Faculty of Medicine, Oslo, Norway, 8Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France, 9Centro Hospitalar Universitario de Coimbra, Coimbra, Coimbra, Portugal

    Background/Purpose: Patient Acceptable Symptom State (PASS) represents the maximum level of symptom intensity that a patient considers acceptable. Control of disease activity is associated with the…
  • Abstract Number: 478 • 2019 ACR/ARP Annual Meeting

    The Influence of Gender on Composite Disease Activity Indices for Rheumatoid Arthritis

    Takahiro NIshino1, Atsushi Hasimoto 1, Shigeto Tohma 2 and Toshihiro Matsui 1, 1National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan, 2National Hospital Organization Tokyo National Hospital, Tokyo, Japan

    Background/Purpose: Disease activity of patients with rheumatoid arthritis should be assessed equally independent of gender, age, or disease duration. However, at present, they are not…
  • Abstract Number: 479 • 2019 ACR/ARP Annual Meeting

    Impact of Achieving Early-sustained Remission on Preventing Long-term Functional Loss in Patients with Early Rheumatoid Arthritis

    Evelyn Chow1, Isaac T. Cheng 1, Lai-Shan Tam 1 and CRYSTAL Study Team Hong Kong 2, 1The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2The Chinese University of Hong Kong, Hong Kong

    Background/Purpose: Preventing functional loss is crucial to early RA (ERA) patients in order to maintain usual activities of daily living. However, whether achieving early and…
  • Abstract Number: 480 • 2019 ACR/ARP Annual Meeting

    Not Achieving Clinical Remission Predicts a Poor Health-Related Quality of Life in Rheumatoid Arthritis Patients: Results of a Latin American Real World Database

    Rocío-V. Gamboa-Cárdenas1, Manuel Ugarte-Gil 2, Cristina Reátegui-S 3, Victor Pimentel-Quiroz 4, Mariela Medina 1, Zoila Rodríguez-Bellido 1, Samira Garcia-H 5, Paola Zeña-Huancas 1, Luciana Gil 1, Erika Noriega 1, Francisco Zevallos-M 1, José Alfaro-Lozano 1, Risto Perich-Campos 1, César-A Pastor-A 6 and Graciela Alarcón 7, 1Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Lima, Peru, 2Universidad Científica del Sur, Lima, Lima, Peru, 3Hospital Nacional Guillermo Almenara Irigoyen, Lima, Lima, Peru, 4Hospital Nacional Guillermo Almenara Irigoyen - EsSalud, Lima, Lima, Peru, 5Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Lima, Peru, 6Universidad Nacional Mayor de San Marcos, Lima, Lima, Peru, 7University of Alabama at Birmingham, Birmingham

    Background/Purpose: Uncontrolled Rheumatoid Arthritis (RA) leads to disability, damage, and poor health-related quality of life (HRQoL). Current treatment recommendations emphasize the importance of achieving remission…
  • Abstract Number: 481 • 2019 ACR/ARP Annual Meeting

    Production of IL17A in Synovial Tissue Correlates with MRI RAMRIS Scores in ACPA Positive Early Rheumatoid Arthritis

    Thomas Kirchgesner1, Christine Galant 2, Bernard Lauwerys 3, Bruno Vande Berg 1, Tatiana Sokolova 4, Laurent Meric de Bellefon 5, Adrien Nzeusseu 5 and Patrick Durez 6, 1Musculoskeletal Imaging Unit, Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, Bruxelles, Belgium, 2Histopathology, Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, Bruxelles, Belgium, 3Rheumatology, Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, Brussels, Belgium, 4Rheumatology, Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, Bruxelles, Belgium, 5Cliniques universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique, Bruxelles, Belgium, 6Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, UCL Saint-Luc, Brussels, Belgium

    Background/Purpose: We previously studied evolution of MRI RAMRIS scores in a group of 28 early rheumatoid (RA) patients treated with first-line infliximab (IFX) versus placebo.…
  • Abstract Number: 482 • 2019 ACR/ARP Annual Meeting

    Antibody Repertoire Sequencing, Antigen Array Analysis, and Cytokine Profiling of Blood from Individuals at High-risk for RA Reveals Candidate Immunoglobulin V Genes, ACPA, and Cytokines That May Promote the Transition to Arthritis

    Radhika Iyer1, Amin Zia 1, Michelle Bloom 1, Sunil Nagpal 2, Navin Rao 2, Frédéric Baribaud 3, George Vratsanos 4, Wei Wang 5, Gary Firestein 6, David Boyle 5, Jane Buckner 7, V. Michael Holers 8, Kevin Deane 9 and William Robinson 10, 1Stanford University, Stanford, 2Janssen R&D, Spring House, PA, 3Janssen Research & Development, LLC, Spring House, PA, 4JNJ, Raritan, NJ, 5University of California, San Diego, San Diego, CA, 6University of California, San Diego, San Diego, 7Benaroya Research Institute, Seattle, WA, 8University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Denver, 9University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, 10Stanford University, Stanford, CA

    Background/Purpose: The “Targeting Immune Responses for Prevention of RA” (TIP-RA) collaboration studies individuals at high risk for developing rheumatoid arthritis (RA) because of serum anti-citrullinated…
  • Abstract Number: 483 • 2019 ACR/ARP Annual Meeting

    Can a Single Question on Functional Impairments Facilitate the Diagnosis of Early Inflammatory Arthritis? A Cross-Sectional Derivation and Validation Study in Two Early Arthritis Recognition Clinics

    Bastiaan van Dijk1, Hanna van Steenbergen 1, Ellis Niemantsverdriet 1 and Annette van der Helm-van Mil 2, 1Leiden University Medical Center, Leiden, Netherlands, 2LUMC, Leiden, Zuid-Holland, Netherlands

    Background/Purpose: Early treatment initiation in RA is associated with improved outcomes but requires early identification of synovitis. Joint swelling in early inflammatory arthritis (IA) may…
  • Abstract Number: 484 • 2019 ACR/ARP Annual Meeting

    Effectiveness of Platelet-derived Microparticles for the Diagnosis and Clinical Evaluation of Rheumatoid Arthritis

    Hideyuki Horikoshi1, Ko Takamatsu 1, Rika Suzuki 1, Yasuyoshi Kusanagi 1, Fumihiko Kimura 1 and Kenji Itoh 1, 1National Defense Medical College Division of Hematology and Rheumatology, Department of Internal Medicine, Tokorozawa, Saitama, Japan

    Background/Purpose: Platelet-derived microparticles (PDMP) are membrane vesicles released from activated platelets and contain various inflammatory or angiogenetic factors; therefore, PDMP may be a new biomarker…
  • Abstract Number: 485 • 2019 ACR/ARP Annual Meeting

    Comparison of Clinical Features, Synovial Histology and Immunohistochemistry in Seropositive Arthralgia, Rheumatoid Arthritis, and Osteoarthritis

    Candice Low1, Richard Conway 2, Francis Young 1, Eamonn Molloy 3, Anne Barbara Mongey 3, Gerry Wilson 3, Ursula Fearon 4 and Douglas Veale 5, 1Saint Vincent's University Hospital, Dublin, Ireland, 2Blackrock Clinic, Dublin, Ireland, 3St Vincent's University Hospital, Dublin, Ireland, 4Molecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland, 5EULAR Centre For Arthritis And Rheumatic Diseases and The Conway Institute, Dublin, Ireland

    Background/Purpose: Seropositive arthralgia is defined as joint pain in patients positive for rheumatoid factor (RF) or anti-citrullinated protein antibodies (ACPA). It is a precursor to…
  • Abstract Number: 486 • 2019 ACR/ARP Annual Meeting

    Evolution of Seropositive Arthralgia over Time: Predictors of Evolution to Rheumatoid Arthritis

    Candice Low1, Richard Conway 2, Francis Young 1, Eamonn Molloy 3, Anne Barbara Mongey 3, Gerry Wilson 3, Ursula Fearon 4 and Douglas Veale 5, 1Saint Vincent's University Hospital, Dublin, Ireland, 2Blackrock Clinic, Dublin, Ireland, 3St Vincent's University Hospital, Dublin, Ireland, 4Molecular Rheumatology, Trinity Biomedical Sciences Institute, TCD, Dublin, Ireland, 5EULAR Centre For Arthritis And Rheumatic Diseases and The Conway Institute, Dublin, Ireland

    Background/Purpose: Seropositive arthralgia is defined as joint pain in patients positive for rheumatoid factor (RF) or anti-citrullinated protein antibodies (ACPA). In some individuals it is…
  • Abstract Number: 487 • 2019 ACR/ARP Annual Meeting

    Third Generation Anti-cyclic Citrullinated Peptide Antibodies Improve Prediction of Clinical Arthritis in Second Generation Anti-cyclic Citrullinated Peptide Positive Subjects at Risk of Rheumatoid Arthritis

    Andrea Di Matteo1, Kulveer Mankia 1, Laurence Duquenne 2, Leticia Garcia-Montoya 1, Diane Corscadden 3, Katie Mbara 3, Jacqueline Nam 1, Michael Mahler 4 and Paul Emery 1, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, England, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, 4Inova Diagnostics, San Diego, CA

    Background/Purpose: ACPA positive individuals with musculoskeletal symptoms are at increased risk of developing RA. In such individuals, ACPA are conventionally identified on the basis of…
  • Abstract Number: 488 • 2019 ACR/ARP Annual Meeting

    Citrullinated Antigens with Multiple Citruline Similar Motif Could Be Used for RA Diagnosis

    zhiwei ru 1, Xuedong Chen 2, Xiaoyan huang 1, Jianrong Lou 1, YongZheng peng 3 and Xiang Yang1, 1Leide bioscience Inc, guang zhou, Guangdong, China (People's Republic), 2Southern Medicine University, guang zhou, Guangdong, China (People's Republic), 3Southern Medicine University, guang dong, Guangdong, China (People's Republic)

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint inflammation that ultimately leads to joint destruction. Diagnosis of RA is important…
  • Abstract Number: 489 • 2019 ACR/ARP Annual Meeting

    S100A11 (calgizzarin) Is Released During Neutrophil Extracellular Traps (NETs) Formation in Rheumatoid Arthritis (RA)

    Adéla Navrátilová1, Jiří Baloun 2, Hana Hulejová 2, Karel Pavelka 3, Jiří Vencovský 3, Ladislav Senolt 3 and Lucie Andrés Cerezo 1, 1Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 2Institute of Rheumatology, Prague, Czech Republic, 3Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic

    Background/Purpose: S100A11 protein, a member of S100 family, has been associated with several autoimmune inflammatory conditions such as rheumatoid arthritis (RA). Moreover, its pro-inflammatory effect…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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