Abstracts Archive - Page 935 of 2425 - ACR Meeting Abstracts

Abstract Number: 2650 • 2019 ACR/ARP Annual Meeting
Predictors of Relapse in Giant Cell Arteritis: Data from an International Collaboration
Laure Delaval ¹, Raphael Porcher ², Kenneth Warrington ³, Francesco Muratore ⁴, Cynthia Crowson ⁵, Daniel Blockmans ⁶, Christian Agard ⁷, Alexis Régent ⁸, Maxime Samson ⁹, Loic Guillevin ⁸, Carlo Salvarani ¹⁰ and Benjamin Terrier⁸, ¹Department of Internal Medicine, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Paris, France, Paris, France, ²Hotel Dieu Hospital, Paris, France, ³Mayo Clinic Rochester, Rochester, MN, ⁴Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁵Mayo Clinic Rochester, Rochester, ⁶Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium, ⁷CHU Nantes, Nantes, France, ⁸National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, ⁹Service de Médecine Interne et Immunologie Clinique, CHU Dijon Bourgogne, Hôpital François Mitterrand, Dijon ; Université Bourgogne-Franche Comté, INSERM, EFS BFC, UMR1098, F-21000 Dijon, Dijon, France, ¹⁰Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: Roughly half of giant-cell arteritis (GCA) patients taking only glucocorticoids (GCs) relapse. The relapse rate seems to reflect, in part, the duration of GC intake, more…
Abstract Number: 2651 • 2019 ACR/ARP Annual Meeting
Are There Phenotypic Overlaps Between Giant Cell Arteritis Subgroups?
Berkan Armagan ¹, Abdullah Yildirim ², Alper Sarı ³, Bayram Farisoğulları ³, Emre Bilgin ³, Levent Kilic ⁴, Umut Kalyoncu ⁵, Şule Apras Bilgen ⁴ and Omer Karadag⁶, ¹Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, ²Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey, ³Hacettepe University Vasculitis Centre, Ankara, Turkey, Ankara, Turkey, ⁴Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ⁵Hacettepe University Department of Rheumatology, Ankara, Turkey, ⁶Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey
Background/Purpose: In parallel to the improvements in imaging, increasing data is accumulated regarding phenotypes of primary vasculitides. Giant cell arteritis (GCA) is a large vessel…
Abstract Number: 2652 • 2019 ACR/ARP Annual Meeting
Comparison Between Transmural and Isolated Periadventitial And/or Adventitial Inflammation at Temporal Artery Biopsy: A Single Center Cohort of Biopsy-Positive GCA with Long Term Follow-up
Elena Galli¹, Francesco Muratore ², Luigi Boiardi ³, Alberto Cavazza ⁴, Giovanna Restuccia ², Luca Cimino ⁵ and Carlo Salvarani ⁶, ¹Division of Rheumatology, University of Modena and Reggio Emilia, Modena, Italy, ²Division of Rheumatology, Azienda Unita’ Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ³Division of Rheumatology, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁴Pathology Unit, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁵Ophthalmology Unit, Azienda Unita' Sanitaria Locale IRCCS di Reggio Emilia, Reggio Emilia, Italy, ⁶Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases, inflammation…
Abstract Number: 2653 • 2019 ACR/ARP Annual Meeting
Adventitial Fibroblast, an Important Actor in Giant Cell Arteritis
Simon Parreau¹, Nicolas Vedrenne ², Alexis Régent ³, Laurence Richard ⁴, Philippe Sindou ², Luc Mouthon ³, Anne-Laure Fauchais ⁴, Marie-Odile Jauberteau ² and Kim Heang Ly ¹, ¹Limoges University Hospital, Limoges, France, ²EA3842-CaPTuR, Limoges, ³National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, ⁴Limoges University Hospital, Limoges
Background/Purpose: Giant cell arteritis (GCA) is a systemic vasculitis affecting large vessels. The diagnosis is based on temporal artery biopsy (TAB) which shows an arterial…
Abstract Number: 2654 • 2019 ACR/ARP Annual Meeting
Comparison of Aortitis and Non-Inflammatory Thoracic Aortic Aneurysms Undergoing Open Surgical Repair
Laarni Quimson ¹, Adam Mayer², Sarah Capponi ², Bryan Rea ³ and Rennie Rhee ⁴, ¹University of Pennsylvania, Division of Internal Medicine, Philadelphia, PA, ²University of Pennsylvania, Internal Medicine/Pediatrics Residency Program, Philadelphia, PA, ³University of Pittsburgh, Department of Pathology, Pittsburgh, PA, ⁴University of Pennsylvania, Division of Rheumatology, Philadelphia, PA
Background/Purpose: Aortitis is challenging to diagnose and is often detected on surgical pathology. A subset of these patients could benefit from early medical therapy as…
Abstract Number: 2655 • 2019 ACR/ARP Annual Meeting
Large Vessel Vasculitis: Diagnosis Is Very Frequent with Ultrasound Examination and Shows Responsiveness to Treatment
Eugenio de Miguel¹, Irene Monjo ², Elisa Fernández ³, Diana Peiteado ⁴, Chamaida Plasencia ⁵ and Alejandro Balsa ⁵, ¹Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ²FIBHULP-IdiPAZ-Hospital La Paz-Rheumatology, Madrid, Spain, ³Rheumatology Department, La Paz University Hospital, Madrid, Madrid, Spain, ⁴Hospital Universitario La Paz, Madrid, ⁵Immuno-Rheumatology Research Group, IdiPaz & Rheumatology Department. La Paz University Hospital, Madrid, Spain
Background/Purpose: Giant cell arteritis (GCA) is the most common systemic vasculitis in the elderly. In the EULAR recommendations of 2018 for the use of imaging…
Abstract Number: 2656 • 2019 ACR/ARP Annual Meeting
The Veterans Health Administration (VHA) National Database Cohort: Incident Ophthalmic Complications in Giant Cell Arteritis (GCA) Patients with a Negative Temporal Artery Biopsy
Sarah Chung¹, Meredith Morcos ², Scott Pollock ¹ and Bernard Ng ³, ¹University of Washington Division of Rheumatology, Seattle, WA, ²University of Washington Division of Rheumatology, Seattle, ³University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA
Background/Purpose: This study aimed to identify the incidence of ophthalmic complication of giant cell arteritis (GCA) among subjects with negative temporal artery biopsy (TAB) and to…
Abstract Number: 2657 • 2019 ACR/ARP Annual Meeting
The Association Between Bisphosphonates and Giant Cell Arteritis: A Retrospective Cohort Study
Salman Mahmood¹, Yuanyuan Ji ², Yi Peng ² and Zaki Abou Zahr ¹, ¹Hennepin Healthcare, Minneapolis, MN, ²Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, MN
Background/Purpose: Bisphosphonates have been used to treat disorders of bone metabolism for several years. A common adverse reaction associated with their use constitutes a transient…
Abstract Number: 2658 • 2019 ACR/ARP Annual Meeting
Giant Cell Arteritis Diagnostic Workup Among Medicare Beneficiaries
Alicia Rodriguez-Pla¹, Lili Zhou ², Erin Ashbeck ³ and C. Kent Kwoh ⁴, ¹University of Arizona/Banner Health Medical Center, Tucson, AZ, ²The University of Arizona Arthritis Center, University of Arizona, Tucson, AZ, Tucson, AZ, ³The University of Arizona Arthritis Center, University of Arizona, Tuccson, AZ, Tucson, AL, ⁴University of Arizona, Tucson, AZ
Background/Purpose: Giant cell arteritis (GCA) has traditionally been diagnosed by a combination of symptoms, clinical findings, laboratory results, and temporal artery biopsy. More recently, imaging…
Abstract Number: 2659 • 2019 ACR/ARP Annual Meeting
Giant-Cell Arteritis Associated with Myeloproliferative Neoplasms: A Retrospective Case–Control Study
Matthias Papo¹, Laure Delaval ¹, Hubert de BOYSSON ², Jean-François Viallard ³, Aurélie Foucher ⁴, Sébastien Humbert ⁵, Pierre Duffau ⁶, Anne Contis ⁷, Christian Agard ⁸, Claude Bachmeyer ⁹, Bruno Gombert ¹⁰, Loic Guillevin ¹¹, Maxime Samson ¹² and Benjamin Terrier ¹¹, ¹Department of Internal Medicine, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Paris, France, Paris, France, ²University Hospital of Caen, Caen, France, ³CHU Bordeaux, Bordeaux, France, ⁴Department of Internal Medicine and Infectious Diseases, Centre Hospitalier Universitaire de la Réunion Saint Pierre, Reunion Island, France., Saint-Pierre, France, ⁵Department of internal medicine, CHU Jean Minjoz, Besancon, France, Besancon, France, ⁶Department of Internal Medicine and Clinical Immunology , Hôpital Saint-André, CHU de Bordeaux , Bordeaux , France., Bordeaux, Aquitaine, France, ⁷Department of Internal Medicine and Clinical Immunology , Hôpital Saint-André, CHU de Bordeaux , Bordeaux , France, Bordeaux, France, ⁸CHU Nantes, Nantes, France, ⁹Department of Internal Medicine, Tenon Hospital (AP-HP), Paris, France, Paris, France, ¹⁰Rheumatology Department, Groupe Hospitalier de la Rochelle Ré Aunis, La Rochelle, France., La Rochelle, France, ¹¹National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France, ¹²CHU Dijon, Dijon, France
Background/Purpose: Giant-cell arteritis (GCA) is a large-vessel vasculitis affecting patients >50 years, whose origin remains widely unelucidated. Recent studies demonstrated that myeloid disease-related somatic mutations…
Abstract Number: 2660 • 2019 ACR/ARP Annual Meeting
Rationalizing the Use of MRI of the Scalp Arteries in the Diagnosis of Giant Cell Arteritis Through Multivariable Predictive Modelling
Mats Junek¹, Angela Hu ², Karen Beattie ³, Kimberly Legault ³, Stephanie Garner ⁴, Ryan Rebello ³ and Nader A. Khalidi ³, ¹McMaster University, Oakville, ²University of Toronto, Toronto, ON, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴McMaster University, Hamilton, Canada
Background/Purpose: It has been historically difficult to develop effective diagnostic strategies and criteria in giant cell arteritis (GCA). While temporal artery biopsy was previously thought…
Abstract Number: 2661 • 2019 ACR/ARP Annual Meeting
A Ten-Year Retrospective Review of Temporal Artery Biopsy Lengths in Alberta
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. The historical gold standard for diagnosis is a…
Abstract Number: 2662 • 2019 ACR/ARP Annual Meeting
Temporal Artery Biopsy Lengths in Alberta: Which Surgical Subspecialty Achieves Optimal Biopsy Lengths?
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. Diagnosis requires a combination of clinical manifestations including…
Abstract Number: 2663 • 2019 ACR/ARP Annual Meeting
Maintained Benefit in Health-Related Quality of Life of Patients with Giant Cell Arteritis Treated with Tocilizumab Plus Prednisone Tapering: Results from the Open-Label, Long-Term Extension of a Phase 3 Randomized Controlled Trial
John Stone¹, Jian Han ², Sebastian Unizony ¹, Martin Aringer ³, Daniel Blockmans ⁴, Elisabeth Brouwer ⁵, Maria C. Cid ⁶, Bhaskar Dasgupta ⁷, Jürgen Rech ⁸, Carlo Salvarani ⁹, Robert Spiera ¹⁰ and Min Bao ², ¹Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ²Genentech, South San Francisco, CA, ³Division of Rheumatology, Department of Medicine III, University Medical Center & Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany, Dresden, Germany, ⁴Department of General Internal Medicine, University Hospitals Gasthuisberg, Leuven, Belgium, ⁵Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁶Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain, ⁷Southend University Hospital, NHS Foundation Trust, Westcliff-on-Sea, United Kingdom, ⁸Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany, ⁹Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ¹⁰Hospital for Special Surgery, New York, NY
Background/Purpose: Patients with giant cell arteritis (GCA) treated with tocilizumab (TCZ) plus prednisone tapering achieved higher rates of sustained glucocorticoid (GC)-free remission and had lower…
Abstract Number: 2664 • 2019 ACR/ARP Annual Meeting
Color Doppler Ultrasound for the Diagnosis of Giant Cell Arteritis in Montreal: A Canadian Single Center Experience
Jean-Paul Makhzoum¹, Meriem Belhocine ¹, Michelle Goulet ¹, Maxime Rheaume ¹, Tara Starnino ², Stephanie Ducharme-Benard ², Guillaume Febrer ³, Yves Troyanov ⁴, Nathalie Routhier ⁵, Rosalie-Selene Meunier ⁵, Isabelle Chagnon ⁵, Michel Laurier ⁵, Maggy Helou ⁵, Nathalie Morency ⁶ and Anne-Marie Mansour ¹, ¹Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ²Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ³Vascular Surgery, Department of Surgery, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ⁴Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁵Internal Medicine, Department of Medicine, Hopital du Sacre-Coeur de Montreal, Montreal, Canada, ⁶Division of Rheumatology, Department of Medicine, Montreal, Canada
Background/Purpose: Giant Cell Arteritis (GCA) remains challenging to diagnose as false negative temporal artery biopsy (TAB) can occur. Color doppler ultrasonography (CDUS) of the temporal,…

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