ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 2170 • 2019 ACR/ARP Annual Meeting

    Risk Factors for Poor Outcomes After Hip Fracture Patients in the Robust Elderly: Are Patient Reported Outcomes Important?

    Lisa Mandl1, Dina Sheira 2, Marianna Frey 3, Jackie Finik 2, Kirsten Grueter 3 and Joseph Lane 4, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY, 2Hospital for Special Surgery, New York, NY, New York, NY, 3Hospital for Special Surgery, New York, NY, New York, 4Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York

    Background/Purpose: Low energy hip fractures are feared harbingers of morbidity and mortality. However, many older adults are high functioning and cognitively intact at the time…
  • Abstract Number: 2171 • 2019 ACR/ARP Annual Meeting

    Functional Exercise for Adults with Chronic Nonspecific Low Back Pain

    Emilia Moreira1, Anamaria Jones 1, Eider Lima 1, Fabio Jennings 2 and Jamil Natour 2, 1Federal University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 2Federal University of São Paulo, São Paulo, Brazil

    Background/Purpose: To assess the effectiveness of a functional exercise program for pain, functional capacity, general health, kinesiophobia, medication consumption and patient satisfaction in adults with chronic…
  • Abstract Number: 2172 • 2019 ACR/ARP Annual Meeting

    Depression of Vitamin D Levels After Adult Primary Posterior Spinal Fusion: Are We Adding Insult to Injury?

    Isabel Smith1, Samuel Golenbock 1, Gerald Miley 2 and Scott Tromanhauser 2, 1New England Baptist Hospital, Boston, MA, 2New England Baptist Hospital, Boston

    Background/Purpose: Vitamin D is a steroid hormone metabolized to its active form in the presence of parathyroid hormone in the kidney. Vitamin D is essential…
  • Abstract Number: 2173 • 2019 ACR/ARP Annual Meeting

    Descriptive Analysis of Patient-Reported Home Exercise and Physical Activity and Their Associations with Patient Baseline Characteristics Following Total Knee Replacement

    Carol Oatis1, Nikko Mendoza 2, William Murray 3, Bailey Novak 4, Wenjun Li 5, Hua Zheng 6 and Patricia Franklin 7, 1Arcadia University, Philadelphia, PA, 2Fox Rehabilitation, Cherry Hill, NJ, 3Physical Therapy and Wellness Institute, Hatfield, PA, 4ATI Physical Therapy, Warrington, PA, 5Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 6Department of Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 7Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Total knee replacement (TKR) is one of the most common elective surgeries and is effective for managing knee pain in osteoarthritis. However functional outcomes…
  • Abstract Number: 2174 • 2019 ACR/ARP Annual Meeting

    Test-Retest Reliability and Validity of a Mobile Health Application to Automate the 30 Seconds Chair Stand Test – Preliminary Data to Create a Contemporary Instrument for Randomized Clinical Trials

    Lucas Dantas1, Matthew Harkey 2, André Dantas 3, Lori Lyn Price 4, Jeffrey Driban 5 and Timothy McAlindon 1, 1Tufts Medical Center, Boston, MA, 2Tufts Medical Center, University of Massachusetts Medical School, Boston, MA, 3CI&T, Tokyo, Japan, 4Tufts Medical Center, Tufts University, Boston, MA, 5Tufts Medical Center, Boston

    Background/Purpose: Contemporary technologies offer potential solutions to improve and automate data collection of randomized clinical trials by transitioning assessments from the clinic to the real-world.…
  • Abstract Number: 2175 • 2019 ACR/ARP Annual Meeting

    Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Doses of the Anti-ADAMTS-5 Nanobody®, M6495, in Healthy Male Subjects: A Phase I, Placebo-Controlled, First-in-Human Study

    Hans Guehring1, Torben Balchen 2, Kosalaram Goteti 3, Jesper Sonne 4, Christoph Ladel 1, Victor Ona 1, Flavie Moreau 5, Anne Bay-Jensen 6 and Asger Reinstrup Bihlet 6, 1Merck KGaA, Darmstadt, Germany, 2DanTrials ApS c/o Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 3EMD Serono Research and Development Institute, Inc., Billerica, MA, 4Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark, 5EMD Serono Research and Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, 6Nordic Bioscience, Herlev, Denmark

    Background/Purpose: Osteoarthritis (OA) is a serious disease characterized by progressive joint failure and cartilage degeneration. In OA, ADAMTS-5 protease is upregulated, resulting in enhanced cleavage…
  • Abstract Number: 2176 • 2019 ACR/ARP Annual Meeting

    A Novel Composite Score Reflecting Disease Activity Predicts Future Knee Replacements: Data from the Osteoarthritis Initiative

    Jeffrey Driban1, Matthew Harkey 2, Lori Lyn Price 3, Grace Lo 4, Jincheng Pang 5, Ming Zhang 6 and Timothy McAlindon 1, 1Tufts Medical Center, Boston, MA, 2Tufts Medical Center, University of Massachusetts Medical School, Boston, MA, 3Tufts Medical Center, Tufts University, Boston, MA, 4Center of Excellence Michael E. DeBakey VAMC, Baylor College of Medicine, Houston, TX, 5Pfizer, Inc., Cambridge, MA, 6Tufts Medical Center, Wentworth Institute of Technology, Boston, MA

    Background/Purpose: While knee osteoarthritis (KOA) leads to cumulative damage to a diarthrodial joint there are also more dynamic processes that fluctuate throughout the disease process…
  • Abstract Number: 2177 • 2019 ACR/ARP Annual Meeting

    Sarcopenia and the Likelihood of Incident Knee Osteoarthritis and Knee Pain Among Older Adults in the Health ABC Study

    James Andrews1, Laura Gold 1, Michael Nevitt 2, Patrick Heagerty 1 and Peggy Cawthon 3, 1University of Washington, Seattle, 2University of California at San Francisco, San Francisco, CA, 3University of California San Francisco, San Francisco

    Background/Purpose: Osteoarthritis (OA) disproportionately affects older adults.  Sarcopenia, or reduced muscle mass and strength, is strongly associated with reduced physical function and poor clinical outcomes…
  • Abstract Number: 2178 • 2019 ACR/ARP Annual Meeting

    Associations Between Baseline and Longitudinal Quantitative Joint Space Width and Incident Hip Osteoarthritis: The Johnston County Osteoarthritis Project

    Jacquelyn Smith1, Carolina Alvarez 1, Liubov Arbeeva 1, Jordan Renner 2, Louise Murphy 3, Joanne Jordan 1, Yvonne Golightly 4, Jeffrey Duryea 5 and Amanda Nelson 1, 1University of North Carolina at Chapel Hill Thurston Arthritis Research Center, Chapel Hill, NC, 2University of North Carolina at Chapel Hill Department of Radiology, Chapel Hill, NC, 3Centers for Disease Control and Prevention, Division of Population Health, Atlanta, 4University of North Carolina at Chapel Hill Department of Epidemiology and Thurston Arthritis Research Center, Chapel Hill, NC, 5Harvard Medical School Department of Radiology Brigham and Women's Hospital, Boston, MA

    Background/Purpose: To quantify associations between baseline and change in computer-assisted hip quantitative joint space width (qJSW) with incident radiographic (rHOA) or symptomatic (sxHOA) hip OA.Methods:…
  • Abstract Number: 2179 • 2019 ACR/ARP Annual Meeting

    Erosive Hand Osteoarthritis, Metabolic Syndrome and Knee Osteoarthritis: A Cross-sectional Study Using Data from the PROCOAC Cohort

    Natividad Oreiro1, Ignacio Rego-Pérez 1, Maria T. Silva 1, Sara Relaño 1, Mercedes Fernandez-Moreno 2, Paula Ramos-Louro 1, Alejandro Duran-Sotuela 1, Sonia Pertega 3 and Francisco J. Blanco 1, 1Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, 2Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España. CIBER-BBM, A Coruña, Spain, 3Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain

    Background/Purpose: Erosive hand osteoarthritis (EOA) is often considered a more severe form of hand OA. However, more data are needed regarding this phenotype to conclude…
  • Abstract Number: 2180 • 2019 ACR/ARP Annual Meeting

    High Molecular Weight Intraarticular Hyaluronic Acid for the Treatment of Knee Osteoarthritis: A Network Meta-Analysis

    Charles Hummer 1, Felix Angst 2, Emil Schemitsch 3, Craig Whittington 4, Colleen Manitt 5 and Wilson Ngai6, 1Premier Orthopaedics and Sports Medicine, Media, PA, 2Research Department, Rehabilitation Clinic (‘RehaClinic’), Bad Zurzach, Switzerland, 3London Health Sciences Centre, London, Ontario, Canada, 4Doctor Evidence, Santa Monica, CA, 5International Centre for Professional Development in Health and Medicine, Quebec, Canada, 6Sanofi, U.S. Medical Affairs, Bridgewater

    Background/Purpose: The 2013 American Academy of Orthopaedic Surgeons (AAOS) clinical practice guideline (CPG) on the treatment of knee OA made a strong recommendation not in…
  • Abstract Number: 2181 • 2019 ACR/ARP Annual Meeting

    Natural Disease Progression in Hand Osteoarthritis: Results from a Belgian Ten-years Prospective Cohort Study

    Lisa Pardaens 1, Tine Vanhaverbeke 1, Jordy Vandercruyssen 1 and Ruth Wittoek2, 1Ghent University, Gent, Belgium, 2Ghent University Hospital, Gent University, Gent, Belgium

    Background/Purpose: Limited evidence is available about natural disease progression in hand osteoarthritis (HOA).  A previous study of the Ghent HOA cohort showed a positive association…
  • Abstract Number: 2182 • 2019 ACR/ARP Annual Meeting

    Relation of MRI-detected Structural Damage in the Knee to Anterior Knee Pain: The MOST Study

    Joshua Stefanik1, Tuhina Neogi 2, Mohamed Jarraya 3, Ali Guermazi 4, Irina Tolstykh 5, John Lynch 6, James Torner 7, Cora Lewis 8 and Erin Macri 9, 1Northeastern University, Boston, 2Boston University School of Medicine, Boston, MA, 3Mercy Catholic Medical Center, Darby, 4Boston Medical Center, Boston, 5UCSF, San Francisco, 6University of California at San Francisco, San Francisco, CA, 7University of Iowa at Iowa City, Iowa City, 8UAB, Birmingham, 9Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: Discordance between knee osteoarthritis (OA) and knee pain is common yet not well understood. Specifically, anterior knee pain (AKP) is widely held to be…
  • Abstract Number: 2183 • 2019 ACR/ARP Annual Meeting

    Relation of Intra-Articular Knee Mineralization on CT to Knee Pain in People with or at Risk of Knee Osteoarthritis

    Tuhina Neogi1, John Lynch 2, Mohamed Jarraya 3, David Felson 4, Na Wang 1, Michael Nevitt 2, James Torner 5, Beth Lewis 6 and Ali Guermazi 1, 1Boston University School of Medicine, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Mercy Catholic Medical Center, Darby, 4Boston University School of Medicine, Department of Rheumatology, Boston, 5University of Iowa at Iowa City, Iowa City, 6University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Intra-articular (i.a.) calcium crystal deposition is common in knee osteoarthritis (OA), particularly in end-stage disease. It is possible that low-grade inflammation related to crystals…
  • Abstract Number: 2184 • 2019 ACR/ARP Annual Meeting

    A Flexion Contracture Is a Risk Factor for Radiographic Progression and Earlier Need for Arthroplasty in Knee Osteoarthritis: Data from the Osteoarthritis Initiative

    T Mark Campbell1 and Dennis McGonagle 2, 1Elisabeth Bruyere Hospital, Ottawa, ON, Canada, 2University of Leeds, Leeds, United Kingdom

    Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis. Knee OA is often accompanied by a knee flexion contracture (FC), but the impact of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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