Abstracts Archive - Page 855 of 2425 - ACR Meeting Abstracts

Abstract Number: 1449 • 2019 ACR/ARP Annual Meeting
Clinical Phenotyping of Patients with Primary Sjögren’s Syndrome Using Salivary Gland Ultrasonograhpy
Esther Mossel¹, Jolien van Nimwegen ¹, Robin Wijnsma ¹, Alja Stel ¹, Konstantina Delli ¹, Greetje van Zuiden ¹, Lisette Olie ¹, Leonie Los ¹, Arjan Vissink ¹, Frans Kroese ¹, Suzanne Arends ² and Hendrika Bootsma ³, ¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²Dept. of Rheumatology and Clinical Immunology - University Medical Center Groningen (UMCG), University of Groningen, Groningen, Netherlands, ³University of Groningen, Groningen, Netherlands
Background/Purpose: Salivary gland ultrasonography (SGUS) is a promising tool in primary Sjögren’s syndrome (pSS). The objective of this study was to investigate SGUS abnormalities in…
Abstract Number: 1450 • 2019 ACR/ARP Annual Meeting
Salivary Gland Hypofunction in a Mouse Model for Sjögren’s Syndrome Is Strongly Associated with Hyperglycemia
Bujana Allushi ¹, Joanna Papinska ¹, Harini Bagavant ¹ and Umesh Deshmukh¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: It has been demonstrated that the non-obese diabetes (NOD) mice from the Jackson Laboratory (JAX) have a distinct gut microbiome and higher incidence of…
Abstract Number: 1451 • 2019 ACR/ARP Annual Meeting
Histological Characteristics in SICCA Syndrome – Clinical and Serological Association
Maria de Lourdes Flores ¹, Gabriela Alejandra Gutierrez-Robles ¹, Flavio Cesar Estrada-Gil ¹, Miguel Alejandro Davalos-Benitez ¹, Jorge Ernesto Garcia-Alvarado ¹, Alejandra de Lourdes Farias-Sierra¹, Ignacio Garcia-De La Torre ², Gerardo Orozco-Barocio ¹, Carlos Gerardo Riebeling-Navarro ³ and Arnulfo Hernan Nava-Zavala ⁴, ¹HGO SSJ, U de G, PNPC CONACYT, Guadalajara, Mexico, ²Centro de Estudios de Investigación Básica y Clínica, S.C., Guadalajara, Jalisco, Mexico, ³UIEC UMAE HP CMN-SXXI IMSS / UNAM, Ciudad de Mexico, Mexico, ⁴UIB02 UMAE HE CMNO IMSS / HGO SSJ / PIM UAG / PNPC U de G, Guadalajara, Mexico
Background/Purpose: The xerostomia and/or xerophtalmia (SICCA syndrome: items I and II of 2002 AECG criteria) are conspicuous characteristics of primary Sjögren´s syndrome (pSS). pSS diagnostic…
Abstract Number: 1452 • 2019 ACR/ARP Annual Meeting
Comparison of Clinical Phenotype, Serological Characteristics and Histologic Features Between Males and Females Patients with Primary Sjögren’s Syndrome (pSS)
Loukas Chatzis¹, Saviana Gandolfo ², Francesco Ferro ³, Marco Binutti ², Valentina Donati ⁴, Sara Zandonella Callegher ⁵, Vasilis Pezoulas ⁶, Aliki Venetsanopoulou ⁷, Argyropoulou Ourania ⁷, Georgios Michalopoulos ⁷, maria pappa ⁷, Clio Mavragani ⁷, Dimitris fotiadis ⁸, Chiara Baldini ³, Salvatore De Vita ², Athanasios Tzioufas ¹ and Andreas Goules ⁷, ¹Department of Pathophysiology, Athens School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, Athens, Greece, ²Rheumatology Clinic, Udine University Hospital, Department of Medical Area, University of Udine, Udine, Italy, Udine, Italy, ³Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, Pisa, Italy, ⁴University of Pisa, Pisa, ⁵Rheumatology Clinic, Udine University Hospital, Udine, Italy, Udine, Italy, ⁶Unit of Medical Technology and Intelligent Information Systems, University of Ioannina, GR45110, Ioannina, Greece, Ioannina, Greece, ⁷Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, Athens, Greece, ⁸Pathophysiology Department, Athens School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, Ioannina, Greece
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a female predominant autoimmune disease and very few studies have been conducted to investigate the phenotypic differences of the…
Abstract Number: 1453 • 2019 ACR/ARP Annual Meeting
Baseline EULAR Sjögren’s Syndrome Patient-Reported Index Has a Significant Impact on the Longitudinal Course of Sjögren’s Syndrome
Eun Hye Park¹, You-Jung Ha ¹, Eun Ha Kang ¹, Yeong-Wook Song ² and Yun Jong Lee ³, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, Seongnam, Republic of Korea, ²Seoul National University Hospital, Seoul, Republic of Korea, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea, Seongnam, Republic of Korea
Background/Purpose: The EULAR Sjögren's syndrome (SS) disease activity index (ESSDAI) and EULAR SS Patient-Reported Index (ESSPRI) have been validated as disease activity and outcome measures…
Abstract Number: 1454 • 2019 ACR/ARP Annual Meeting
Sjӧgren’s Syndrome Foundation National Survey: The Impact and Burden of Oral Symptoms
Sara McCoy¹, Christie Bartels ², Esen Akpek ³, Ian Saldanha ⁴, Vatinee Bunya ⁵, Matthew Makara ⁶ and Alan Baer ⁷, ¹University of Wisconsin School of Medicine and Public Health, Madison, ²University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Johns Hopkins University, Baltimore, ⁴Brown University School of Public Health, Providence, RI, ⁵University of Pennsylvania, Philadelphia, PA, ⁶Sjogren's Syndrome Foundation, Reston, VA, ⁷Johns Hopkins University, Baltimore, MD
Background/Purpose: Sjӧgren’s syndrome (SS) is the second most common systemic autoimmune disease, typically characterized by ocular and oral sicca. SS is associated with reduced quality…
Abstract Number: 1455 • 2019 ACR/ARP Annual Meeting
B and T Cell Immunologic Features Associated with Higher Disease Activity Score and Focus Score in Primary Sjögren Syndrome
Alice Mai¹, Yuriy Baglaenko ², Dario Ferri ³, Kieran Manion ⁴, Dennisse Bonilla ⁵, Arthur Bookman ⁶ and Joan Wither ⁷, ¹University of British Columbia Department of Rheumatology, Vancouver, Canada, ²Brigham Woman's Hospital, Boston, ³University Health Network, Toronto, ON, Canada, ⁴Krembil Research Institute, Toronto, ON, Canada, ⁵University Health Network, University of Toronto, Toronto, ON, Canada, ⁶University Health Network, Toronto, Canada, ⁷University Health Network, Krembil Research Institute, Toronto, ON, Canada
Background/Purpose: Primary Sjögren syndrome (pSS) is a systemic autoimmune disease with an incompletely understood pathogenesis and heterogenous disease manifestations. Identifying cellular immune changes that may…
Abstract Number: 1456 • 2019 ACR/ARP Annual Meeting
The Increased Ratio of Blood CD56bright to CD56dim NK Cells Is a Distinguishing Feature of Primary Sjögren’s Syndrome
Bingxia Ming ¹, Tong Wu ¹ and Lingli Dong², ¹Department of Rheumatology and Immunology, Tongji hospital, Huazhong university of science and technology, Wuhan, China (People's Republic), ²Department of Rheumatology and Immunology, Tongji hospital, Huazhong university of science and technology, Wuhan, Hubei, China (People's Republic)
Background/Purpose: To investigate the characteristic and clinical significance of peripheral blood CD56 NK cell subsets in patients with primary Sjögren's syndrome (pSS).Methods: From November 2017…
Abstract Number: 1457 • 2019 ACR/ARP Annual Meeting
Neurological Involvement in a Cohort of Primary Sjogren’s Syndrome Patients: Results of a Multicenter Italian Study
Elena Bartoloni¹, Chiara Baldini ², Luca Quartuccio ³, Roberta Priori ⁴, Francesco Carubbi ⁵, Francesco Ferro ², Saviana Gandolfo ³, Angelica Gattamelata ⁶, Alessia Alunno ⁷, Stefano Bombardieri ⁸, Salvatore De Vita ³, Roberto Giacomelli ⁵, Vittorio Bini ⁷ and Roberto Gerli ¹, ¹Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy, Perugia, Italy, ²Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, Pisa, Italy, ³Rheumatology Clinic, Udine University Hospital, Department of Medical Area, University of Udine, Udine, Italy, Udine, Italy, ⁴Rheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy, Roma, Italy, ⁵Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, Italy, L'Aquila, Italy, ⁶University of Roma Sapienza, Rome, Italy, ⁷University of Perugia, Perugia, Italy, ⁸Rheumatology Unit, University of Pisa, Pisa, Italy, Pisa, Italy
Background/Purpose: The course of primary Sjögren’s syndrome (pSS) may be characterized by extra-glandular and potentially life-threatening manifestations. Among these, neurological involvement represents a clinical challenge…
Abstract Number: 1458 • 2019 ACR/ARP Annual Meeting
Dual Analysis with Nerve Ultrasound and Skin Biopsy in Painful Neuropathy Associated with Sjögren’s Syndrome
Takeshi Yoshida¹, Hiroyuki Nodera ², Yoshitaka Kumon ³ and Hiroki Mizukami ⁴, ¹Chikamori Hospital, Kochi, Japan, ²Kanazawa Medical University, Kanazawa, Japan, ³Chikamori Hospital, Kochi, ⁴Hirosaki University, Hirosaki, Japan
Background/Purpose: 6% of primary Sjögren's syndrome (pSS) patients manifests as various forms of neuropathies including painful sensory neuropathy (PSN), which can be treatable with immunomodulatory drugs such…
Abstract Number: 1459 • 2019 ACR/ARP Annual Meeting
Systemic Manifestations of Primary Sjögren Syndrome out of the ESSDAI Classification: Prevalence and Clinical Relevance in a Large International, Multi-ethnic Cohort of Patients
Soledad Retamozo¹, Nihan Acar-Denizli ², Astrid Rasmussen ³, Ildiko Fanny Horváth ⁴, Chiara Baldini ⁵, Roberta Priori ⁶, Pulukool Sandhya ⁷, Gabriela Hernandez-Molina ⁸, Berkan Armagan ⁹, SONJA PRAPROTNIK ¹⁰, Marika Kvarnstrom ¹¹, Roberto Gerli ¹², Agata Sebastian ¹³, Roser Solans-Laqué ¹⁴, Maureen Rischmueller ¹⁵, Sandra G. Pasoto ¹⁶, Valeria Valim ¹⁷, Gunnel Nordmark ¹⁸, Aike Kruize ¹⁹, Takashi Nakamura ²⁰, Benedikt Hofauer ²¹, Roberto Giacomelli ²², Virginia Fernandes Moça Trevisani ²³, Valérie Devauchelle Pensec ²⁴, Fabiola Atzeni ²⁵, Tamer A Gheita ²⁶, Sandra Consani-Fernández ²⁷, Antonia Szántó ²⁸, Kathy Sivils ³, Angelina Gattamelata ²⁹, Debashish Danda ⁷, Levent Kilic ³⁰, Elena Bartoloni ¹², Stefano Bombardieri ³¹, Jorge Sánchez-Guerrero ³², Marie Wahren-Herlenius ¹¹, Xavier Mariette ³³, Manuel Ramos-Casals ³⁴ and Pilar Brito-Zerón ³⁵, ¹Instituto De Investigaciones En Ciencias De La Salud, Univ. Nacional de Córdoba, Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Universitario de Ciencias Biomédicas de Córdoba, Córdoba, Argentina., Cordoba, Argentina, ²Department of Statistics, Faculty of Science and Letters, Mimar Sinan Fine Arts University, Istanbul, Turkey., Istanbul, Turkey, ³Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., Oklahoma, OK, ⁴Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Debrecen, Hungary, ⁵Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, Pisa, Italy, ⁶Rheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy, Roma, Italy, ⁷Department of Clinical Immunology & Rheumatology, Christian Medical College & Hospital, Vellore, India., Vellore, India, ⁸Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁹Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, ¹⁰Department of Rheumatology, University Medical Centre, Ljubljana, Slovenia., LJUBLJANA, Slovenia, ¹¹Department of Medicine, Solna, Division of Experimental Rheumatology, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden., Stockholm, Sweden, ¹²Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy, Perugia, Italy, ¹³Department of Rheumatology and Internal Medicine, Wroclaw Medical Hospital, Wroclaw, Poland, Wroclaw, Poland, ¹⁴Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain., Barcelona, Catalonia, Spain, ¹⁵Department of Rheumatology, The Queen Elizabeth Hospital and University of Adelaide, South Australia, Australia, ¹⁶Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Brazil, ¹⁷Department of Medicine, Federal University of Espírito Santo, Vitória, Brazil., Vitória, Brazil, ¹⁸Rheumatology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Uppsala, Sweden, ¹⁹Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Utrecht, Netherlands, ²⁰Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Nagasaki, Japan, ²¹Otorhinolaryngology, Head and Neck Surgery, Technical University Munich, Munich, Germany., Munich, Germany, ²²Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, Italy, L'Aquila, Italy, ²³Department of Evidence-Based Medicine, Brazilian Cochrane Centre, Federal University of São Paulo, Sao Paulo, Brazil, Sao Paulo, Brazil, ²⁴University Hospital of Brest, Brest, France, ²⁵Rheumatology Unit, University of Messina, Messina, Italy., Messina, Italy, ²⁶Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt., Cairo, Egypt, ²⁷Internal Medicine, Hospital Maciel, Montevideo, Uruguay. Universidad de la República (UdelaR) , Montevideo, Uruguay., Montevideo, Uruguay, ²⁸Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, Debrecen, Hungary, ²⁹Department of Internal Medicine and Medical Specialties, Rheumatology Clinic, Sapienza University of Rome, Rome, Italy, Rome, Italy, ³⁰Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ³¹Rheumatology Unit, University of Pisa, Pisa, Italy, Pisa, Italy, ³²Immunology and Rheumatology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. México City, Mexico, Mexico, Mexico, ³³Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France, ³⁴Department of Autoimmune Diseases, ICMiD. Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX. Department of Medicine, University of Barcelona, Hospital Clínic, Barcelona, Spain., Barcelona, Spain, ³⁵Sjögren Syndrome Research Group (AGAUR), Laboratory of Autoimmune Diseases Josep Font, IDIBAPS-CELLEX, Department of Autoimmune Diseases, ICMiD, University of Barcelona, Hospital Clínic. Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona, Spain., Barcelona, Spain
Background/Purpose: To analyse the frequency and characterize the systemic presentation of primary Sjögren syndrome (SjS) out of the ESSDAI classification in a large international, multi-ethnic…
Abstract Number: 1460 • 2019 ACR/ARP Annual Meeting
Minor Salivary Gland Biopsy and Dry Ocular Tests to Detect Occult Sjögren Syndrome in Patients with Interstitial Pneumonia with Autoimmune Features
Maria Garbarino¹, Santiago Auteri ², Maria Blanco ³, Laura Alberti ⁴, FRANCISCO PAULIN ⁵, Martin Fernandez ⁴, Gabriel Carballo ⁶, Mercedes Raya ⁴, Gabriela Guman ⁴ and FABIAN CARO ⁵, ¹Hospital Argerich, Buenos Aires, Argentina, ²Hospital Ferrer, Rosario, Argentina, ³Hospital Lagleyze, Buenos Aires, Argentina, ⁴Hospital Ferrer, Buenos Aires, Argentina, ⁵HOSPITAL MARIA FERRER, Buenos Aires, Argentina, ⁶Hospital Durand, Buenos Aires, Argentina
Background/Purpose: Interstitial lung disease (ILD) are a heterogeneous group of diseases that could be either idiopathic or secondary to environmental exposure, drugs or connective tissue…
Abstract Number: 1461 • 2019 ACR/ARP Annual Meeting
Pulmonary Cysts: Very Common Finding on Computed Tomography of the Chest of Asymptomatic Patients with Primary Sjögren’s Syndrome
Alisson Pugliesi¹, Pamella Bellini ², Rachel Zerbini Mariano ², Manoel Bertolo ² and Zoraida Sachetto ¹, ¹University of Campinas, Campinas, Sao Paulo, Brazil, ²University of Campinas, Campinas, Brazil
Background/Purpose: The presence of pulmonary cysts is a relatively unusual radiological finding, but frequently described in patients with primary Sjögren's syndrome (pSS). Its true meaning,…
Abstract Number: 1462 • 2019 ACR/ARP Annual Meeting
Pathogenesis of Vaginal Dryness in Primary Sjögren’s Syndrome: A Histopathological Case-control Study
Jolien van Nimwegen¹, Karin van der Tuuk ¹, Sylvia Liefers ¹, Gwenny Verstappen ¹, Robin Wijnsma ¹, Harry Hollema ¹, Marian Mourits ¹, Hendrika Bootsma ² and Frans Kroese ¹, ¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²University of Groningen, Groningen, Netherlands
Background/Purpose: Women with primary Sjögren’s syndrome (pSS) often experience vaginal dryness, but the pathogenesis of this symptom is unknown. Previously, we reported impaired vaginal health…
Abstract Number: 1463 • 2019 ACR/ARP Annual Meeting
Positive Rate of Small Intestinal Bacterial Overgrowth Test (SIBO) Was Significant Correlations to Disease Activity of Primary Sjogren’s Syndrome (pSS)
xiaodong li ¹, Xiao feng li ², sha dong³, Sheng-xiao Zhang ⁴, Junwei Chen ⁵ and guangying liu ³, ¹Second Affiliated Hospital of Shanxi Medical University, tai yuan, China (People's Republic), ²The Second hospital of Shanxi Medical University, Taiyuan, China (People's Republic), ³Second Affiliated Hospital of Shanxi Medical University, taiyuan, China (People's Republic), ⁴The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China (People's Republic), ⁵the Second Hospital of Shanxi Medical University, Taiyuan, China (People's Republic)
Background/Purpose: Primary Sjogren's syndrome (pSS) is a chronic inflammatory autoimmune disease that primarily affects the exocrine glands, which is involved in gastrointestinal unavoidably. Once intestinal flora imbalance,…

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