Abstracts Archive - Page 837 of 2425 - ACR Meeting Abstracts

Abstract Number: 1179 • 2019 ACR/ARP Annual Meeting
Resting-State Functional Connectivity of Pain Processing Brain Region Associated with Therapeutic Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis
Nobuya Abe¹, Yuichiro Fujieda ¹, Kuniyuki Asou ¹, Kohei Karino ², Michihito Kono ³, Hisashi Narita ⁴, Masaru Kato ¹, Khin Tha ⁵, Kenji Oku ¹, Olga Amengual ¹, Shinsuke Yasuda ¹ and Tatsuya Atsumi ⁶, ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ³Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, ⁴Department of Psychiatry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁵Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ⁶Hokkaido University, Sapporo, Japan
Background/Purpose: Background/Purpose: Discriminating inflammatory pain from non-inflammatory pain is critical to determine therapeutic strategy in inflammatory arthritis (IA) such as rheumatoid arthritis (RA) and spondyloarthritis…
Abstract Number: 1180 • 2019 ACR/ARP Annual Meeting
Confirmation of Manual Cartilage Segmentation Findings by Automated Segmentation: Retrospective Analysis of MRI Images from a Sprifermin Phase II Study
Alan Brett¹, Michael A Bowes ¹, Philip G Conaghan ², Christoph Ladel ³, Jeffrey Kraines ⁴, Hans Guehring ³, Flavie Moreau ⁴ and Felix Eckstein ⁵, ¹Imorphics, Manchester, United Kingdom, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ³Merck KGaA, Darmstadt, Germany, ⁴EMD Serono Research and Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁵Paracelsus Medical University, Salzburg, Austria
Background/Purpose: Sprifermin is under investigation as a potential disease-modifying osteoarthritis drug (DMOAD). 2-yr results from the FORWARD study showed significant dose-dependent modification of cartilage thickness…
Abstract Number: 1181 • 2019 ACR/ARP Annual Meeting
Tocilizumab in Aortitis: A Multicenter Study of 79 Patients
Mónica Calderón-Goercke¹, Javier Loricera ², DIANA PRIETO- PENA ³, Vicente Aldasoro Caceres ⁴, Santos Castañeda ⁵, Ignacio Villa ⁶, Alicia Humbría ⁷, Clara Moriano ⁸, Susana Romero-Yuste ⁹, Javier Narváez ¹⁰, Catalina Gómez-Arango ¹¹, Eva Perez Pampín ¹², Rafael Melero ¹³, Marcelino Revenga ¹⁴, Noelia Álvarez-Rivas ¹⁵, Francisca Sivera ¹⁶, María Álvarez del buergo ¹⁷, Luisa Marena-Rojas ¹⁸, Eva Galindez-Agirregoikoa ¹⁹, Beatriz Arca ²⁰, Roser Solans-Laqué ²¹, Carlos Vazquez ²², Pau Lluch ²³, Eva salgado-Pérez ²⁴, Cristina Luna-Gómez ²⁵, F. Javier Toyos-Sáenz De Miera ²⁶, Nagore Fernández-Llanio ²⁷, Antonio García ²⁸, Carmen Larena ²⁹, Lara Sanchez-Bilbao ¹, Iñigo Gonzalez-Mazon ³, Natalia Palmou-Fontana ³, Vanesa Calvo-Río ¹, Carmen González-Vela ¹, Alfonso Corrales ³⁰, María Varela-García ⁴, Elena Aurrecoechea ⁶, Raquel Dos Santos ³¹, Sabela Fernández ²⁰, Jose Luis Hernández ¹, Miguel Angel González-Gay ³² and Ricardo Blanco ³³, ¹Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ²Rheumatology Department. Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁴Complejo Hospitalario de Navarra, Navarra, Navarra, Spain, ⁵Rheumatology Department, Hospital Universitario de la Princesa, IIS-Princesa, Madrid, Spain, Madrid, Spain, ⁶Hospital de Sierrallana, Torrelavega, Cantabria, Spain, ⁷Hospital de La Princesa, Madrid, Madrid, Spain, ⁸Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁹Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain, ¹⁰Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, Barcelona, Catalonia, Spain, ¹¹Hospital Alto Deba, Mondragon, Pais Vasco, Spain, ¹²Division of Rheumatology, Instituto de Investigación Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, Santiago de Compostela, Spain, ¹³Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, ¹⁴Hospital Ramón y Cajal, Madrid, Madrid, Spain, ¹⁵Hospital Universitario Lucus Augusti, Lugo, Galicia, Spain, ¹⁶Hospital General Universitario de Elda, Elda, Spain, ¹⁷Hospital Río Carrión, Palencia, Castilla y Leon, Spain, ¹⁸Hospital La Mancha Centro, Alcázar de San Juan, Castilla-La Mancha, Spain, ¹⁹Hospital de Basurto, Bilbao, Pais Vasco, Spain, ²⁰Hospital Universitario San Agustín, Avilés, Asturias, Spain, ²¹Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain., Barcelona, Catalonia, Spain, ²²Hospital Miguel Servet, Zaragoza, Aragon, Spain, ²³Hospital Mateu Orfila, Menorca, Islas Baleares, Spain, ²⁴Complejo Hospitalario Universitario de Ourense, Ourense, Galicia, Spain, ²⁵Hospital Universitario Nuestra Señora de la Candelaria, Tenerife, Canarias, Spain, ²⁶Hospital Universitario Virgen Macarena, Sevilla, Andalucia, Spain, ²⁷Hospital Arnau de Vilanova, Lérida, Catalonia, Spain, ²⁸Hospital Virgen de las Nieves, Granada, Andalucia, Spain, ²⁹Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain, ³⁰Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, Santander, Spain, ³¹Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Galicia, Spain, ³²Universidad de Cantabria and IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain
Background/Purpose: Aortitis can be idiopathic or associated with other conditions. It is frequently refractory to conventional immunosuppressive therapy. Tocilizumab (TCZ), an anti-IL-6 receptor antibody seems…
Abstract Number: 1182 • 2019 ACR/ARP Annual Meeting
Fluorescence Optical Imaging in the Diagnosis of Individuals Suspected of Arthritis Development – a Probabilistic Approach
Yogan Kisten¹, Adrian Levitsky ¹, Hamed Rezaei ¹, Aase Hensvold ², Per Larsson ³, Erik af Klint ¹, Ronald van Vollenhoven ⁴ and Anca Catrina ⁵, ¹Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Stockholms Lan, Sweden, ²Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, ³Center for Rheumatology, Academic Specialist Center, Stockholm Health Services, Stockholm, Sweden, Stockholm, Stockholms Lan, Sweden, ⁴Amsterdam Rheumatology and immunology Center, Netherlands., Amsterdam, Netherlands, ⁵Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden
Background/Purpose: Among the arsenal of available techniques for arthritis prediction and diagnosis, fluorescence optical imaging (FOI) has shown to be useful in detecting clinically manifest…
Abstract Number: 1183 • 2019 ACR/ARP Annual Meeting
Gout and Serum Urate Levels Are Associated with Lumbar Spine Monosodium Urate Deposition and Chronic Low Back Pain: A Dual-Energy CT Study
Michael Toprover¹, Anastasia Slobodnick ², Courtney Pike ³, Cheongeun Oh ⁴, Claudine Davis ², Michael Mechlin ⁵ and Michael H Pillinger ⁶, ¹Rheumatology Division, NYU Langone Health and Rheumatology Section, NY Harbor Health Care System, Department of Veterans Affairs., New York, NY, ²Rheumatology Division, NYU Langone Health, New York, ³Rheumatology Section, NY Harbor VA Healthcare System, New York, ⁴Biostatistics Department, NYU Langone Health, New York, ⁵Musculoskeletal Radiology, NYU Langone Health, New York, ⁶Rheumatology Division, NYU Langone Health and Rheumatology Section, NY Harbor Health Care System, Department of Veterans Affairs., New York
Background/Purpose: More than 130 cases of gout of the spine have been reported, with presenting symptoms including acute back pain, neuropathy, and spinal compression; diagnosis…
Abstract Number: 1184 • 2019 ACR/ARP Annual Meeting
Rheumatoid Arthritis Activity Assessment with Cellphone Thermal Camera Imaging Compared to Clinical and Ultrasound Assessments
Caroline Paris ¹, Pierre Lafforgue ¹, Vincent Pradel ², Christophe Richez ³ and Thao Pham¹, ¹Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, ²APHM -Assistance publique des hôpitaux de Marseille, Marseille, Finland, ³Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France
Background/Purpose: The assessment of active joints is a core component of widely used outcome measures in rheumatoid arthritis (RA). However, variability exists within and across…
Abstract Number: 1185 • 2019 ACR/ARP Annual Meeting
New Imaging Modality to Evaluate Arthritis in Lupus Based on Frequency-domain Optical Transmission
Anca Askanase¹, Fiamma Van Biema ², Alessandro Marone ², Youngwan Kim ², Tommy Chen ², Teja Kapoor ², Laura Geraldino ², Yevgeniya Gartshteyn ³ and Andreas Hielscher ², ¹Columbia University Medical Center, New York, NY, ²Columbia University School of Medicine, New York, NY, ³Columbia University School of Medicine, Glen Rock, NJ
Background/Purpose: 95% of the people with SLE experience joint pain, stiffness and swelling at some time during their illness. It is currently difficult to both…
Abstract Number: 1186 • 2019 ACR/ARP Annual Meeting
How Accurate Is Physical Joint Inflammation of the MTP-joints and What Can We Learn from Additional MRI on Forefoot Involvement in Early Arthritis?
Yousra Dakkak¹, Aleid Boer ¹, Debbie Boeters ¹, Annette van der Helm-van Mil ² and Monique Reijnierse ¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²LUMC, Leiden, Zuid-Holland, Netherlands
Background/Purpose: Magnetic resonance imaging (MRI) is more sensitive than physical examination in detecting inflammation. This has predominantly been studied in metacarpophalangeal-(MCP) and wrist-joints. Data on…
Abstract Number: 1187 • 2019 ACR/ARP Annual Meeting
Delayed Gadolinium-enhanced MR Imaging of Cartilage – A Pilot Study to Measure the Effect of Adalimumab Plus MTX versus Placebo Plus MTX on Cartilage in Early RA Patients (CAR-ERA-Study)
Philipp Sewerin¹, Miriam Frenken ², Ralph Brinks ³, Christoph Schleich ², Daniel Benjamin Abrar ², Stefan Vordenbaeumen ⁴, Ruben Sengewein ⁵, Jutta Richter ⁶, Matthias Schneider ⁷ and Benedikt Ostendorf ⁴, ¹Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ²Institute for Diagnostic and Interventional Radiology, UKD, Heinrich Heine University, Duesseldorf, Germany, ³Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ⁴Policlinic and Hiller Research Unit of Rheumatology, UKD, Heinrich Heine University, Duesseldorf, Germany, ⁵Policlinic and Hiller Research Unit of Rheumatology,, Duesseldorf, Germany, ⁶Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, ⁷Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany
Background/Purpose: The purpose of this longitudinal study is to compare the effect of Adalimumab plus Methotrexate (MTX) versus MTX monotherapy on glycosaminoglycan content (GAG) in…
Abstract Number: 1188 • 2019 ACR/ARP Annual Meeting
Novel PET-Coronary Flow Reserve Imaging to Assess for Coronary Microvascular Dysfunction in Systemic Lupus Erythematosus Compared to Subjects with Diabetes Mellitus and Controls
Cameron Speyer¹, Corine Sinnette ¹, Emma Stevens ¹, Hongshu Guan ², Courtney Bibbo ², Marcelo Di Carli ², Karen Costenbader ¹ and Elena Massarotti ², ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston
Background/Purpose: High risk of premature cardiovascular disease (CVD) among SLE patients is well documented, but the best means to detect the earliest stages of CVD…
Abstract Number: 1189 • 2019 ACR/ARP Annual Meeting
Baylor Rheumatology Initiative: Developing and Guiding Engagement (BRIDGE) Transition Pathway Creation and Implementation
Priyanka Moolchandani¹, Cristina Saez ¹, Marietta DeGuzman ¹, Eyal Muscal ¹, Andrea Ramirez ¹, Anna Carmela Sagcal-Gironella ¹, Saimun Singla ¹, Amanda Brown ¹, Monica Marcus ¹, Martha Curry ¹, Maria Pereira ¹, M. Brad Nelson ¹, Pooja Patel ¹, W. Blaine Lapin ¹, Jennifer Rammel ¹, LeeGee Huang ², Blanca Sanchez-Fournier ², JaLeen Rogers ², Ariel Washington ², Anne Dykes ², Miriah Gillispie-Taylor ¹ and Tiphanie Vogel ¹, ¹Baylor College of Medicine, Houston, TX, ²Texas Children's Hospital, Houston, TX
Background/Purpose: Patients with pediatric rheumatologic diseases live well into adulthood, necessitating transition from pediatric to adult medical providers. GotTransition.org details 6 core elements clinicians can…
Abstract Number: 1190 • 2019 ACR/ARP Annual Meeting
A Quality Improvement Project to Increase Documentation Efficiency in an Academic Rheumatology Practice
David Leverenz¹, Jon Golenbiewski ¹, Brian Andonian ¹, Katherine Kaufman ¹, Philip Chu ¹, Mithunan Maheswaranathan ¹, Andrew Johannemann ¹, Jayanth Doss ² and Lisa Criscione-Schreiber ², ¹Duke University, Durham, NC, ²Duke University, Durham
Background/Purpose: All providers, including rheumatologists, spend approximately half of their day documenting in an electronic health record (EHR). Excessive documentation is a key contributor to…
Abstract Number: 1191 • 2019 ACR/ARP Annual Meeting
Application of the Systemic Lupus Erythematosus (SLE) Quality Indicators in Patients Attending a Young Adult Transition Program
Aos Aboabat¹, Earl D. Silverman ² and Amanda Steiman ¹, ¹University of Toronto, Toronto, ON, Canada, ²Division of Rheumatology, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Translational Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada
Background/Purpose: Systemic lupus erythematosus is a multisystemic rheumatic disease affecting 1 in 1000 individuals with a 10:1 female predominance. Childhood-onset SLE (CSLE) constitutes approximately 15%…
Abstract Number: 1192 • 2019 ACR/ARP Annual Meeting
Effect of a Clinical Decision Support System on a Quality Indicator of Glucocorticoid-induced Osteoporosis and Trends of Drug Treatment in a Japanese Hospital
Hiroki Ozawa¹, Sho Fukui ¹, Genki Kidoguchi ¹, Takehiro Nakai ², Satoshi Kawaai ¹, Ayako Koido ¹, Yukihiko Ikeda ¹, Masei Suda ¹, Haruyuki Yanaoka ¹, Hisanori Shimizu ¹, Hiromichi Tamaki ¹, Tokutaro Tsuda ¹, Mitsumasa Kishimoto ³, Kenichi Yamaguchi ¹ and Masato Okada ¹, ¹St.Luke International Hospital Immuno-Rheumatology Center, Tokyo, Japan, ²St.Luke International Hospital Immuno-Rheumatology Center, Tokyo, Tokyo, Japan, ³Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan
Background/Purpose: Glucocorticoid-induced osteoporosis (GIOP) is a common, preventable and treatable complication of glucocorticoid therapy. We defined quality indicator (QI) for GIOP and took a hospital-wide…
Abstract Number: 1193 • 2019 ACR/ARP Annual Meeting
EMR-integrated Disease Activity Calculators Improve Treatment to Target in Rheumatoid Arthritis
Gabrielle Barbera¹, Jasleen Kahlon ², Manank Patel ³, Scott Pompa ⁴ and Arundathi Jayatilleke ¹, ¹Drexel, Philadelphia, PA, ²Hahnemann, Philadelphia, PA, ³Rutgers, New Brunswick, NJ, ⁴Dartmouth, Lebanon, NH
Background/Purpose: Undertreatment of RA can lead to cumulative joint damage as well as negatively impact emotional health. Recent evidence favors a treat-to-target strategy to achieve…

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