ACR Meeting Abstracts

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  • Abstract Number: 1164 • 2019 ACR/ARP Annual Meeting

    Novel Computer Assisted Methodology for Quantitative Assessment of MRI Treatment Responses to Apremilast in Patients with Psoriatic Arthritis

    Paul Bird 1, Mikael Boesen 2, Mark Hinton 3, Eser Sanverdi 3, Romiesa Hagoug 3, Chrisotpher Sabin 3, Priscila Nakasato 4, Benoit Guerette 4 and Olga Kubassova5, 1Optimus Research, Kogarah, New South Wales, Australia, 2Dept. of Radiology, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, 3Image Analysis Ltd, London, United Kingdom, 4Celgene Corporation, Summit, 5Image Analysis Group, London, United Kingdom

    Background/Purpose: Response to treatment in Psoriatic Arthritis (PsA) can be captured using the OMERACT PsA Magnetic Resonance Imaging Score (PsAMRIS). While reliable and valid, PsAMRIS…
  • Abstract Number: 1165 • 2019 ACR/ARP Annual Meeting

    Utility of Coronary Calcium Scoring (CCS) in the Spectrum of Connective Tissue Disorders (CTDs) for the Evaluation of Subclinical Coronary Atherosclerosis – a Systematic Review

    Sohail Farshad1, Alexandra Halalau 2, Whitney Townsend 3 and Elena Schiopu 4, 1Department of Internal Medicine, Beaumont Health System, Royal Oak, MI, 2Department of Internal Medicine, Beaumont Health System, Royal Oak, 3University of Michigan, Ann Arbor, 4Department of Rheumatology, University of Michigan, Ann Arbor

    Background/Purpose: Recent literature shows that connective tissue disorders (CTDs) are positively associated with subclinical atherosclerosis via chronic activation of inflammatory pathways, or direct endothelial injury.…
  • Abstract Number: 1166 • 2019 ACR/ARP Annual Meeting

    A New Risk Factor for Predicting the Long-term Outcome of Pulmonary Arterial Hypertension Associated with Connective Tissue Disease: Pulmonary Artery Size Measured by Chest Computed Tomography

    xiaodi li1, xiaoxuan sun 1, yinsu zhu 1, Qiang wang 1 and miaojia zhang 2, 1A new risk factor for predicting the long-term outcome of pulmonary arterial hypertension associated with connective tissue disease: pulmonary artery size measured by chest computed tomography, Nanjing, China (People's Republic), 2c, Nanjing, China (People's Republic)

    Background/Purpose: Most of the prognostic indicators are derived from right cardiac catheterization or biomarkers in patients with CTD-PAH. It is not clear whether the non-invasive…
  • Abstract Number: 1167 • 2019 ACR/ARP Annual Meeting

    To Evaluate Spine Ankylosis, Vertebral Fractures and Bone Fragility on a Single Imaging Exam in Patients with Ankylosing Spondylitis: Myth or Reality?

    caroline Morizot1, Marine Fauny 2, Edem Allado 3, Frank Verhoeven 4, Eliane Albuisson 5, Astrid Pinzano-Watrin 6, Isabelle Chary-Valckenaere 5 and Damien Loeuille 7, 1Department Of rheumatology, Vandoeuvre les Nancy, Lorraine, France, 2CHU Nancy, Vandoeuvre, France, 3CHRU Nancy, VANDOEUVRE, France, 4Univeristy of Franche comté, Besancon, France, 5Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, 6IMoPA. UMR 7365 CNRS, Vandoeuvre, France, 7Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France

    Background/Purpose: Spine ankylosis is a risk factor of osteoporosis and mortality in ankylosing spondylitis (AS). Recently, thoracic-abdomino-pelvic CT (TAP-CT) has demonstrated its ability to screen…
  • Abstract Number: 1168 • 2019 ACR/ARP Annual Meeting

    Frequently Encountered Artifacts in Novel Application of Dual-Energy CT to Vascular Imaging: A Pilot Study

    Chio Yokose1, Sterling Eide 2, F. Joseph Simeone 1, Kam Shojania 3, Savvas Nicolaou 4, Fabio Becce 5 and Hyon K. Choi 1, 1Massachusetts General Hospital, Boston, MA, 2National University Hospital of Singapore, Singapore, Singapore, 3Vancouver General Hospital, Vancouver, Canada, 4Vancouver General Hospital, Vancouver, BC, Canada, 5Lausanne University Hospital, Lausanne, Switzerland

    Background/Purpose: One hypothesized link between cardiovascular disease and gout is the direct deposition of monosodium urate (MSU) crystals in atherosclerotic plaque. A 2018 ACR abstract…
  • Abstract Number: 1169 • 2019 ACR/ARP Annual Meeting

    Influence of Steroid Treatment on 18F-FDG PET/CT Accuracy to Detect Vascular and Musculoeskeletal Involvement in Patients with Polymyalgia Reumatica

    DIANA PRIETO- PENA1, Mónica Calderón-Goercke 2, Isabel Martínez Rodríguez 3, Ignacio Banzo 3, Lara Sanchez-Bilbao 4, Iñigo Gonzalez-Mazon 1, Belén Atienza-Mateo 4, Miguel Angel González-Gay 5 and Ricardo Blanco 4, 1Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, 2Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, 3Hospital Universitario Marqués de Valdecilla, Santander, Spain, 4Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, 5Universidad de Cantabria and IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain

    Background/Purpose: Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT has been proposed as a promising tool for assessing both musculoskeletal and vascular involvement in patients with polymyalgia rheumatica (PMR). Glucocorticoids…
  • Abstract Number: 1170 • 2019 ACR/ARP Annual Meeting

    Cortical Bone Erosion in the 2nd Metacarpal Bone Head: Association with Its Bone Mineral Density by HR-pQCT in Rheumatoid Arthritis Patients

    Camille Figueiredo1, Mariana Perez 1, Ana Cristina de Medeiros Ribeiro 2, Valeria Caparbo 1 and Rosa Pereira 3, 1Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 2Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil

    Background/Purpose: Periarticular trabecular bone loss and local cortical bone erosions are typical features of bone disease in rheumatoid arthritis (RA) 1 . Little, however, is…
  • Abstract Number: 1171 • 2019 ACR/ARP Annual Meeting

    Evidence of Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Minimal Disease Activity – Interim Analysis

    Victoria Furer1, Ari Polachek 2, Liran Mendel 1, David Levartovsky 3, Jonathan Wollman 4, Valerie Aloush 5, Ilana Kaufman 6, Hagit Sarbagil-Maman 7, Sara Borok 6, Mark Berman 6, Adi Broyde 6, Yael Lahat 1, Mirna Zureik 1, Sharon Nevo 1, Daphna Paran 6, Iris Eshed 8 and Ori Elkayam 6, 1Sourasky Medical Center, Tel-Aviv, Israel, 2Tel-Aviv Sourasky medical center, Tel Aviv, Israel, 3Sourasky medical center, Tel Aviv, Israel, 4Sourasky Medical Center, Herzelia, Israel, 5Tel Aviv Sourasky medical center, Tel Aviv, 6Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 7Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, 8Sheba Medical Center, Tel Aviv, Israel

    Background/Purpose: Subclinical inflammatory lesions detected by MRI are prevalent in hand joints of patients with cutaneous psoriasis (1). Yet, it is unknown whether these inflammatory…
  • Abstract Number: 1172 • 2019 ACR/ARP Annual Meeting

    The Relationship Between Subclinical Inflammation and Bone Damage in Patients with Rheumatoid Arthritis Using Multimodality Imaging

    Scott Brunet 1, Peter Salat 2, Glen Hazlewood 3, Klaus Engelke 4, Cheryl Barnabe 3 and Sarah Manske3, 1University of Calgary, Calgary, Canada, 2University of Calgary, Calary, Canada, 3University of Calgary, Calgary, AB, Canada, 4Erlangen University Hospital, Department of Medicine, Erlangen, Germany

    Background/Purpose: Many RA patients in clinical remission have evidence of bone marrow edema (BME) on magnetic resonance imaging (MRI), with radiographic bone damage progression appearing…
  • Abstract Number: 1173 • 2019 ACR/ARP Annual Meeting

    Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression

    Signe Møller-Bisgaard1, Kim Hørslev-Petersen 2, Bo Ejbjerg 3, Merete Lund Hetland 4, Lykke Midtbøll Ørnbjerg 1, Daniel Glinatsi 1, Jakob Møller 5, Mikael Boesen 6, Kristian Stengaard-Pedersen 7, Ole Rintek Madsen 8, Bente Jensen 9, Jan Alexander Villadsen 10, Ellen-Margrethe Hauge 7, Philip Bennett 11, Oliver Hendricks 12, Karsten Asmussen 9, Marcin Kowalski 13, Hanne Lindegaard 14, Henning Bliddal 15, Niels Steen Krogh 16, Torkell Ellingsen 17, Agnete Nielsen 18, Lone Balding 5, Anne Grethe Jurik 19, Henrik Thomsen 5 and Mikkel Østergaard 20, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, 2Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, 3Department of Rheumatology, Zealand University Hospital, Køge, Denmark, Køge, Denmark, 4DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, 5Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, 6Department of Radiology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, 7Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, 8Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 9Department of Rheumatology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, 10Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, 11Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte, Hellerup, Denmark, Copenhagen, Denmark, 12Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, 13Department of Rheumatology, Hjørring Hospital, Hjørring, Denmark, Hjørring, Denmark, 14Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, 15The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, 16Zitelab / DANBIO, Copenhagen, Denmark, 17Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark, 18Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, 19Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, 20Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Progression of structural joint damage develops in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Known predictors of structural damage progression…
  • Abstract Number: 1174 • 2019 ACR/ARP Annual Meeting

    Prevalence of Subclinical Sacroiliitis in Young Patients with Inflammatory Bowel Disease Revealed by Entero-MRI

    Teresa Giani1, Marco Di Maurizio 2, Paolo Lionetti 2, Azzurra Bernardini 2, Giovanna Ferrara 1, Viola Filistrucchi 2 and Rolando Cimaz 3, 1Anna Meyer Children University Hospital, Florence, Italy, 2A. Meyer Children University Hospital, Florence, Italy, 3Meyer Children's Hospital in Florence, Florence, Italy

    Background/Purpose: Sacroiliitis is one of the extraintestinal manifestations associated with inflammatory bowel disease (IBD), and may be underdiagnosed especially in the pediatric age. MR-enterography (Entero-MRI)…
  • Abstract Number: 1175 • 2019 ACR/ARP Annual Meeting

    Periarticular Inflammation and Bone Marrow Oedema Are Important in the Evaluation of Enthesitis on MRI in Patients with Peripheral and Axial SpA

    Xenofon Baraliakos1, Philipp Sewerin 2, Eugenio de Miguel 3, Christine Kleinmond 4, Ankita Shekhawat 5, Annette Wiedon 6 and Frank Behrens 7, 1Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 2Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, 3Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, 4ClinProject GmbH, Eurasburg, Germany, 5Novartis Healthcare Pvt. Ltd., Hyderabad, India, 6Novartis Pharma GmbH, Nürnberg, Germany, 7CIRI/Rheumatology and Fraunhofer TMP, Goethe-University, Frankfurt, Germany

    Background/Purpose: Enthesitis is a hallmark feature of Spondyloarthritis (SpA), and frequently localizes at the Achilles tendon1. Enthesitis is predominantly measured with clinical scores like Leeds…
  • Abstract Number: 1176 • 2019 ACR/ARP Annual Meeting

    Development and Validation of a Preliminary MRI Sacroiliac Joint Composite Structural Damage Score in a 5-year Longitudinal Study of Patients with Axial Spondyloarthritis

    Marie Wetterslev1, Mikkel Østergaard 2, Inge Juul Sørensen 3, Ulrich Weber 4, Anne Gitte Loft 5, Gina Kollerup 6, Lars Juul 6, Gorm Thamsborg 6, Ole Rintek Madsen 7, Jakob Møller 8 and Susanne Juhl Pedersen 3, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Ø, Hovedstaden, Denmark, 2Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, 3Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, 4Danish Hospital for Rheumatic Diseases, Soenderborg, Denmark, Gråsten, Syddanmark, Denmark, 5Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, 6Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, 7Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, 8Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark

    Background/Purpose: In patients with axial spondyloarthritis (axSpA), MRI reliably detects structural lesions in the sacroiliac joints (SIJs). The SPARCC Sacroiliac joint (SIJ) Structural Score (SSS)(1)…
  • Abstract Number: 1177 • 2019 ACR/ARP Annual Meeting

    Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare

    Richard Bell1, Homaira Rahimi 2, Alicia Lieberman 2, Ronald Wood 2, Edward Schwarz 3 and Christopher Ritchlin 4, 1University of Rochester Medical Center, Rochester, NY, 2University of Rochester Medical Center, Rochester, 3University of Rochester, Rochester, NY, 4Division of Allergy, Immunology and Rheumatology, Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA, Rochester, NY

    Background/Purpose: Near infrared (NIR) imaging of indocyanine green (ICG) in rheumatoid arthritis (RA) models identified abnormal lymphatic vessel (LV) function, which can be quantified as…
  • Abstract Number: 1178 • 2019 ACR/ARP Annual Meeting

    Clinical Utility of DECT in the Diagnosis of Gout at Mayo Clinic in Florida

    Emily Gilbert1, Hillary Garner 1 and Andy Abril 1, 1Mayo Clinic, Jacksonville, FL

    Background/Purpose: Gout is the most common inflammatory arthritis in the United States and worldwide. Precipitation of monosodium urate crystals in joints and soft tissues leads…
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