ACR Meeting Abstracts

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  • Abstract Number: 1280 • ACR Convergence 2020

    COVID-19 Infections May Increase the Risk of SLE Flares

    Leila Khalili1, Yevgeniya Gartshteyn2, Nancyanne Schmidt3, Teja Kapoor4, Laura Geraldino-Pardilla5 and Anca Askanase3, 1Columbia University Medical Center, New York, NY, 2Columbia University College of Physicians and Surgeons, Glen Rock, NJ, 3Columbia University College of Physicians and Surgeons, New York, NY, 4Columbia University College of Physicians and Surgeons, Leonia, NJ, 5Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York

    Background/Purpose: COVID-19 has overwhelmed the healthcare systems in New York City. Initial data from the Columbia Lupus Cohort suggests that 4% of patients with systemic…
  • Abstract Number: 1281 • ACR Convergence 2020

    Opioid-Related Encounters as a Predictor of 30-Day Readmissions in Lupus

    Christie Bartels1, Maria Schletzbaum2, Yi Chen3 and Amy Kind4, 1University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI, 2University of Wisconsin-Madison School of Medicine and Public Health, Department of Population Health Sciences, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Department of Biostatistics and Medical Informatics, Madison, WI, 4University of Wisconsin-Madison School of Medicine and Public Health, Department of Medicine, Health Services and Care Research Program, Geriatrics Division, Madison, WI

    Background/Purpose: One in four Medicare hospitalizations with systemic lupus erythematosus (SLE) results in readmission within 30 days, with “injuries and poisonings” as the second most…
  • Abstract Number: 1282 • ACR Convergence 2020

    The Impact of High Disease Activity as Measured by SLEDAI and Drug Burden on Healthcare Utilization, Quality of Life and Work Productivity in Systemic Lupus Erythematosus Patients

    Zahi Touma1, Benjamin Hoskin2, Christian Atkinson2, David Bell3, James Pike2, Jennifer Lofland4, Pamela Berry5, Chetan Karyekar5 and Karen Costenbader6, 1University of Toronto, Toronto, ON, Canada, 2ADELPHI REAL WORLD, Bollington, United Kingdom, 3ADELPHI REAL WORLD, Bollington, Macclesfield, United Kingdom, 4Janssen Global Market Access, horsham, PA, 5Janssen Global Services, LLC, Horsham, PA, 6Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Although there is abundant literature on healthcare utilization in SLE patients, the impact of disease activity in SLE patients is not well understood.To quantify…
  • Abstract Number: 1283 • ACR Convergence 2020

    Factors Affecting Mortality of Systemic Lupus Erythematosus Patients in Spain in the 21st Century: Data from the RELESSER Registry

    Clara Moriano1, Jaime Calvo-Alén2, Iñigo Rúa-Figueroa3, Elvira Díez Álvarez1, Cristina Bermúdez4, Francisco J López-Longo5, Maria Galindo-Izquierdo6, Alejandro Olivé-Marqués7, Eva Tomero Muriel8, Antonio Fernandez-Nebro9, Mercedes Freire-González10, Olaia Fernandez-Berrizbeitia11, Ana Pérez Gómez12, Maria Esther Uriarte13, Carlos Marras Fernández-Cid14, Carlos Montilla Morales15, Gregorio Santos Soler16, Ricardo Blanco17, Manuel Rodríguez-Gómez18, Paloma Vela19, Alina Lucica Boteanu20, Francisco Javier Narváez21, Victor Martinez Taboada22, Blanca Hernández Cruz23, Jose Luis Andreu Sanchez24, Jose A Hernández-Beriain25, Lorena Expósito26, Raul Menor Almagro27, Mónica Ibañez-Barceló28, Ivan Castellvi29, Carlos Galisteo30, Enrique Raya31, VE Quevedo-Vila32, Tomás Vázquez33, J Ibáñez-Ruan34 and Jose Maria Pego-Reigosa35, 1Complejo Asistencial Universitario de León, León, Spain, 2Hospital Universitario Araba, Vitoria-Gasteiz, Pais Vasco, Spain, 3Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Spain, 4Research Unit Bioaraba, Vitoria, Spain, 5Hospital General Universitario Gregorio Marañón, Madrid, Spain, 6Hospital Universitario 12 de Octubre, Madrid, Spain, 7Hospital Germans Trias i Pujol, Barcelona, Spain, 8Hospital Universitario de la Princesa, Madrid, Madrid, Spain, 9University of Malaga, Malaga, Spain, 10CHU Coruña, Coruña, Spain, 11Basurto University Hospital, Bilbao, Spain, 12Hospital Universitario Príncipe Asturias, Alcalá de Henares, Madrid, Spain, 13Hospital Universitario Donostia, San Sebastian, Spain, 14Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain, 15Hospital Universitario de Salamanca, Salamanca, Spain, 16Hospital Marina Baixa, Alicante, Spain, 17Hospital Universitario Marques de Valdecilla, Santander, Spain, 18Hospital Complex of Ourense, Ourense, Spain, 19Hospital General Alicante, Alicante, Spain, 20PRINTO, Istituto Giannina Gaslini, Genova, Italy, 21Hospital Bellvitge, BARCELONA, Spain, 22Marqués de Valdecilla University Hospital, Santander, Spain, 23Universidad de Sevilla, Sevilla, Spain, 24Hospital Universitario Puerta de Hierro, Majadahonda, Spain, 25Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain, 26Hospital Clinico Tenerife, Tenerife, Spain, 27Hospital General Universitario de Jerez de la Frontera, Puerto De Santa Mar�a, Spain, 28Hospital Son Llatzer, Mallorca, Spain, 29Hospital Santa Creu i Sant Pau, Barcelona, Spain, 30Hospital Parc Taulí, Barcelona, Spain, 31Hospital San Cecilio, Granada, Spain, 32Hospital Comarcal de Monforte, Lugo, Spain, 33Hospital Lucus Augusti, Lugo, Spain, 34Hospital Povisa, Vigo, Pontevedra, Spain, 35University Hospital of Vigo, Galicia Sur Health Research Institute, Vigo, Spain

    Background/Purpose: The mortality in Systemic Lupus Erythematosus (SLE) varies largely across different countries most probably due to social, healthcare and ethnic differences.To analyze the causes…
  • Abstract Number: 1284 • ACR Convergence 2020

    Application of a Novel Method for Determination of Muscle Mass Relative to Fat Mass in Women with Systemic Lupus Erythematosus and Association with Disability

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Patients with SLE are at risk for both skeletal muscle loss and increased adiposity, which may predispose to worse health-related quality of life. Decreased…
  • Abstract Number: 1285 • ACR Convergence 2020

    Association of Frailty with Disability Is Not Attenuated by Lean Body Mass in Women with SLE

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Frailty has been associated with disability and mortality in SLE. Whether this association is confounded by sarcopenia, a degenerative loss of muscle mass and…
  • Abstract Number: 1286 • ACR Convergence 2020

    Personalizing Cardiovascular Risk Prediction for Patients with Systemic Lupus Erythematosus by Physician Global Assessment of Disease Activity

    May Choi1, Emma Stevens2, Hongshu Guan2, Daniel Li3, Jack Ellrodt4, Benjamin Kargere4, Tianrun Cai2, Kazuki Yoshida5, Brendan Everett2 and Karen Costenbader6, 1Brigham and Women's Hospital | Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2Brigham and Women's Hospital, Boston, MA, 3Harvard, Columbus, OH, 4Williams College, Williamstown, 5Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 6Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: The risk of cardiovascular disease (CVD), including myocardial infarction and stroke, is higher in SLE than in the general population. The excess risk of…
  • Abstract Number: 1287 • ACR Convergence 2020

    Prevalence of Morbidity Prior to Diagnosis of Incident Systemic Lupus Erythematosus in the Danish Population

    Julia Simard1, Mikkel Faurschou2, Soeren Jacobsen2 and Renata Hansen2, 1Stanford Medicine, Stanford, CA, 2Copenhagen Lupus and Vasculitis Clinic, Copenhagen, Denmark

    Background/Purpose: Patients with SLE experience a high burden of various comorbidities at disease onset and during disease progression. Studies of excess morbidity prior to SLE…
  • Abstract Number: 1288 • ACR Convergence 2020

    Predictors of Frailty Identified by the Short Physical Performance Battery and Associations with Patient-reported Outcomes

    Patricia Katz1, Jinoos Yazdany2, Laura Trupin3, Stephanie Rush2, Cristina Lanata3, Lindsey Criswell4 and Maria Dall'Era5, 1University of California, San Francisco, Novato, CA, 2University of California, San Francisco, San Francisco, CA, 3UCSF, San Francisco, CA, 4Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California San Francisco, San Francisco, CA, 5Division of Rheumatology, University of California, San Francisco, CA

    Background/Purpose: Frailty, defined as a generalized vulnerability to stressors, has emerged as a relevant concept in SLE1, although its origins are in geriatrics.  As defined…
  • Abstract Number: 1289 • ACR Convergence 2020

    Sex Differences in Mental Health and Quality of Life and Their Impact in the Treatment of Patients with Systemic Lupus Erythematosus

    Lilian Cano-Cruz1, Eduardo Aguirre-Aguilar1, Martín Valdez-López2, Ana Barrera-Vargas1, Virginia Pascual Ramos1 and Javier Merayo-Chalico3, 1INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Mexico City, Distrito Federal, Mexico, 2INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Mexico City, Mexico, 3INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Ciudad de Mexico, Distrito Federal, Mexico

    Background/Purpose: Systemic lupus erythematosus (SLE) predominantly affects young women. It is usually more aggressive in men and carries a worse prognosis. Information about gender differences…
  • Abstract Number: 1290 • ACR Convergence 2020

    A Multitrait-Multimethod Matrix Approach to the Construct Validity of Patient Reported Outcomes Measurement Information System Computerized (PROMIS) Adaptive Tests (CAT) in Systemic Lupus Erythematous

    Mitra Moazzami1, Patricia Katz2, Dennisse Bonilla3, Lisa Engel4, Jiandong Su5, Pooneh Akhavan6, Nicole Anderson5, Oshrat Tayer-Shifman7, Dorcas Beaton8 and Zahi Touma9, 1George Washington University School of Medicine, Washington, DC, 2University of California, San Francisco, Novato, CA, 3University Health Network, Toronto, Canada, 4University of Manitoba, Toronto, ON, Canada, 5University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada, 6Univesity of Toronto, Toronto, ON, Canada, 7Meir Medical Center, Raanana, Israel, 8Institue for Work and Health, Toronto, ON, Canada, 9University of Toronto, Toronto, ON, Canada

    Background/Purpose: Use of The Patient Reported Outcomes Measurement Information System computerized adaptive test (PROMIS-CAT) in adults with systemic lupus erythematous (SLE) is an emerging research…
  • Abstract Number: 1291 • ACR Convergence 2020

    Depressed Symptomatology Persists over Time in the Majority of Systemic Lupus Erythematosus Patients and Is Independent of Disease Activity

    Sara Kellahan1, Xinliang Huang1, Daphne Lew2, Hong Xian3, Seth Eisen1 and Alfred Kim4, 1Division of Rheumatology, Washington University in St. Louis School of Medicine, St. Louis, 2Division of Biostatistics, Washington University in St. Louis School of Medicine, St. Louis, 3Department of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, St. Louis, 4Washington University School of Medicine, St. Louis, MO

    Background/Purpose: Depression is a prevalent (24-30%) and significant comorbidity in patients with systemic lupus erythematosus (SLE) (1).  As the American College of Rheumatology (ACR) classifies…
  • Abstract Number: 1292 • ACR Convergence 2020

    Frequency and Predictors of Influenza Vaccine Hesitancy in Systemic Autoimmune Rheumatic Diseases

    Valeria Valerio1, Mariana Useche1, Mianbo Wang2, Sasha Bernatsky3, Christian Pineau4 and Ines Colmegna1, 1The Research Institute of the McGill University Health Centre, Montreal, Canada, 2Lady Davis institute for Medical Research, Montreal, QC, Canada, 3The Research Institute of the McGill University Health Centre, Montreal, ON, Canada, 4McGill University Health Center, Montreal, QC, Canada

    Background/Purpose: Patients with systemic autoimmune rheumatic diseases (SARDs) benefit from getting annual inactivated influenza vaccine (IIV). However, vaccine uptake among SARDs is suboptimal.  The delay…
  • Abstract Number: 1293 • ACR Convergence 2020

    Factors Associated with Early Hospital Readmission in Systemic Lupus Erythematosus: Data from National Readmission Database

    Rashmi Dhital1, Joshua Baker2, Paras Karmacharya3, Anthony Donato4 and Dilli Poudel2, 1Reading Hospital and Medical Center, West Reading, 2University of Pennsylvania, Philadelphia, PA, 3Mayo Clinic, Rochester MN, ROCHESTER, MN, 4Reading Hospital and Medical Center, West Reading, PA

    Background/Purpose: Early hospital readmission is a major healthcare burden. Studies evaluating factors associated with readmissions in rheumatic diseases are sparse. Our aim was to use…
  • Abstract Number: 1294 • ACR Convergence 2020

    Prediction of Damage in SLE Using Unbiased Analysis of Large Datasets

    Eric Morand1, Dinith Liyanage2, Rita Hoang2, Vera Golder2, Worawit Louthrenoo3, Shue Fen Luo4, Yeong-Jian Wu5, Sargunan Sockalingam6, Susan Morton7, Sandra Navarra8, Leonid Zamora9, Laniyati Hamijoyo10, Yasuhiro Katsumata11, Masayoshi Harigai12, Madelynn Chan13, Sean O'Neill14, Fiona Goldblatt15, Chak Sing Lau16, Zhanguo Li17, Julie Bonin2, Rachel Koelmeyer2, Mandana Nikpour18, Rangi Kandane-Rathnayake2 and Hieu Nim2, 1Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia, 2Monash University, Clayton, Victoria, Australia, 3Chiang Mai University Hospital, Muang, Thailand, 4Chang Gung Memorial Hospital-Linkou, Taoyuan, Taipei, Taiwan (Republic of China), 5Chang Gung Memorial Hospital, Guishan, Taiwan (Republic of China), 6University of Malaya, Kuala Lumpur, Malaysia, 7Monash Health, Clayton, Victoria, Australia, 8University of Santo Tomas, Manila, Philippines, 9University of Santo Thomas, Manila, Philippines, 10University of Padjadjaran, Bandung, Indonesia, 11Tokyo Women's Medical University School of Medicine, Tokyo, Japan, 12Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan, 13Tan Tock Seng Hospital, Singapore, Singapore, 14Sydney University, Sydney, Australia, 15Royal Adelaide Hospital, Adelaide, Australia, 16Hong Kong University, Hong Kong, Hong Kong, 17Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing, China (People's Republic), 18The University of Melbourne at St. Vincent's Hospital, Melbourne, Victoria, Australia

    Background/Purpose: A key goal of treatment of SLE is the prevention of irreversible organ damage. The ability to identify patients at increased risk for damage…
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