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  • Abstract Number: 1266 • ACR Convergence 2020

    Multivariate Risk Model Shows Different Risk Factors for Myocardial Infarction and Stroke in SLE

    Michelle Petri1, Jessica Li2 and Daniel Goldman1, 1Johns Hopkins University School of Medicine, Timonium, MD, 2Johns Hopkins University, Baltimore, MD

    Background/Purpose: Cardiovascular events remain a major cause of morbidity and mortality in SLE. Accelerated atherosclerosis occurs in SLE and many other inflammatory diseases.  In the…
  • Abstract Number: 1272 • ACR Convergence 2020

    Impact of Remission and Low Disease Activity Status on Hospitalizations Among SLE Patients from the GLADEL Latin American Cohort

    Guillermo Pons-Estel1, Manuel Ugarte-Gil2, Guillermina Harvey3, Daniel Wojdyla4, Rosana Quintana1, Rosa Serrano-Morales1, José Gómez-Puerta5, Mercedes García6, Luis Catoggio7, Verónica Saurit8, Cristina Drenkard9, Nilzio Antonio Da Silva10, Fernando Cavalcanti11, Eduardo Borba12, Emilia Sato13, Oscar Neira14, Loreto Massardo15, Gloria Vásquez16, Luis Alonso Gonzalez17, Marlene Guibert Toledan18, Luis Silveira19, Ignacio García De La Torre20, María Josefina Sauza del Pozo21, Rosa Chacón22, Mario Cardiel23, Graciela Alarcón24 and Bernardo Pons-Estel25, 1Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Argentina, 2Servicio de Reumatología. Hospital Nacional Guillermo Almenara Irigoyen and Universidad Científica del Sur, Lima, Peru, 3Guillermina Escuela de Estadística, Facultad de Ciencias Económicas y Estadística, Universidad Nacional de Rosario, Rosario, Argentina, 4GLADEL consultant, Rosario, Argentina, 5Servicio de Reumatología, Hospital Clinic., Barcelona, Spain, 6Servicio de Reumatología del HIGA San Martin de La Plata, La Plata, Argentina, 7Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 8Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 9Division of Rheumatology, Department of Medicine, Emory School of Medicine, Atlanta, GA, 10Reumatologia/Departamento de Clínica Médica, Hospital das Clínicas, Universidade Federal de Goiás, Goias, Brazil, 11Serviço de Reumatologia, Departamento de Medicina Clínica, Centro de Ciências Médicas, Hospital das Clínicas, Universidade Federal de Pernambuco, Pernambuco, Brazil, 12Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 13Escola Paulista de Medicina, Universidad Federal São Paulo, São Paulo, Brazil, 14Sección de Reumatología, Hospital del Salvador, Universidad de Chile, Santiago, Chile, 15Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile, 16Grupo de Inmunología Celular e Inmunogenética, Facultad de Medicina, Universidad de Antioquía, Medellín, Colombia, 17Sección de Reumatología, Departamento de Medicina Interna, Universidad de Antioquía, Medellín, Colombia, 18Marlene Centro de Investigaciones Médicas Quirúrgicas, Havana, Cuba, 19Departamento de Inmunología / Departamento de Reumatología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico, 20Departamento de Inmunología y Reumatología, Hospital General de Occidente de la S.S. y Universidad de Guadalajara, Jalisco, Mexico, 21Instituto Mexicano de Seguro Social, Hospital de Especialidades Nº 25, Monterrey, Mexico, 22Servicio de Reumatología, Policlínica Méndez Gimón, Caracas, Venezuela, 23Centro de Investigación Clínica de Morelia, Morelia, Mexico, 24Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham; Department of Medicine, School of Medicine; Universidad Peruana Cayetano, Heredia, Alabama, 25Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Santa Fe, Argentina

    Background/Purpose: To determine whether remission and low disease activity state (LDAS) reduce hospitalizations in systemic lupus erythematosus (SLE) patients.Methods: A multi-ethnic, multi-national Latin-American SLE cohort…
  • Abstract Number: 1271 • ACR Convergence 2020

    Post-Traumatic Stress Disorder (PTSD) and Risk of Systemic Lupus Erythematosus (SLE) Among Medicaid Recipients

    Siobhan Case1, Candace Feldman1, Hongshu Guan1, Laura Kubzansky2, Karestan Koenan2 and Karen Costenbader3, 1Brigham and Women's Hospital, Boston, MA, 2Harvard T.H. Chan School of Public Health, Boston, MA, 3Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Post-traumatic stress disorder (PTSD), the sentinel stress-related mental disorder, may be associated with increased risk of developing autoimmune disease, including systemic lupus erythematosus (SLE).…
  • Abstract Number: 1277 • ACR Convergence 2020

    Low Cost Composite Markers to Differentiate Infection from Disease Activity in a Febrile Patient with Systemic Lupus Erythematosus

    Pankti Mehta1, Komal Singh1, Amita Aggarwal1 and Seema Sharma1, 1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

    Background/Purpose: Patients with Systemic Lupus Erythematosus (SLE) are at an increased risk of infection owing to immunosuppressive therapy along with coexistent immune dysregulation. It is…
  • Abstract Number: 1279 • ACR Convergence 2020

    Clinical Characteristics and Impact of the COVID-19 Pandemic in Systemic Lupus Erythematosus Patients in a Spanish Tertiary Hospital

    Andrea Briones-Figueroa1, María Jesús García-Villanueva2, África Andreu Suárez1, Marina Tortosa-Cabañas2, Ana Corral-Bote2, Sandra Garrote-Corral2, Javier Bachiller-Corral1 and Mónica Vázquez1, 1Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, 2Hospital Universitario Ramón y Cajal, Madrid, Spain

    Background/Purpose: Data about incidence, clinical characteristics and outcome of patients with Systemic Lupus Erythematosus (SLE) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease is…
  • Abstract Number: 1274 • ACR Convergence 2020

    COVID-19 in Patients with Systemic Lupus Erythematosus

    Ruth Fernandez-Ruiz1, Mala Masson1, Mimi Kim2, Benjamin Myers3, Rebecca Haberman4, Jose Scher4, Rochelle Castillo4, Allison Guttmann1, Philip Carlucci1, Kristina Deonaraine1, Michael Golpanian5, Kimberly Robins1, Miao Chang1, H. Michael Belmont6, Jill Buyon7, Ashira Blazer6, Amit Saxena8 and Peter Izmirly9, 1New York University School of Medicine, New York, 2Albert Einstein College of Medicine, Bronx, 3Cornell University, Ithica, NY, 4NYU School of Medicine, New York City, 5New York University, New York, NY, 6NYU School of Medicine, New York, NY, 7Department of Medicine, NYU School of Medicine, New York, NY, 8NYU School of Medicine, New York, 9Department of Medicine, New York University School of Medicine, New York, NY

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) represent a unique population in considering risk for coronavirus disease 2019 (COVID-19) with biologic, genetic, demographic, clinical and…
  • Abstract Number: 1269 • ACR Convergence 2020

    Evaluation of a Patient-reported Frailty Tool in Women with Systemic Lupus Erythematosus

    Sarah Lieber1, Stephen Paget1, Jessica Berman1, Medha Barbhaiya2, Lisa Sammaritano2, Kyriakos Kirou1, John Carrino3, Musarrat Nahid4, Mangala Rajan4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Barbara Volcker Center for Women and Rheumatic Diseases, New York, NY, 3Hospital for Special Surgery, Hackensack, NJ, 4Weill Cornell Medicine, New York

    Background/Purpose: Frailty has been associated with increased disability and mortality in SLE. To our knowledge, no patient-reported frailty tool has been evaluated alongside a standard…
  • Abstract Number: 1282 • ACR Convergence 2020

    The Impact of High Disease Activity as Measured by SLEDAI and Drug Burden on Healthcare Utilization, Quality of Life and Work Productivity in Systemic Lupus Erythematosus Patients

    Zahi Touma1, Benjamin Hoskin2, Christian Atkinson2, David Bell3, James Pike2, Jennifer Lofland4, Pamela Berry5, Chetan Karyekar5 and Karen Costenbader6, 1University of Toronto, Toronto, ON, Canada, 2ADELPHI REAL WORLD, Bollington, United Kingdom, 3ADELPHI REAL WORLD, Bollington, Macclesfield, United Kingdom, 4Janssen Global Market Access, horsham, PA, 5Janssen Global Services, LLC, Horsham, PA, 6Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Although there is abundant literature on healthcare utilization in SLE patients, the impact of disease activity in SLE patients is not well understood.To quantify…
  • Abstract Number: 1285 • ACR Convergence 2020

    Association of Frailty with Disability Is Not Attenuated by Lean Body Mass in Women with SLE

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Frailty has been associated with disability and mortality in SLE. Whether this association is confounded by sarcopenia, a degenerative loss of muscle mass and…
  • Abstract Number: 1286 • ACR Convergence 2020

    Personalizing Cardiovascular Risk Prediction for Patients with Systemic Lupus Erythematosus by Physician Global Assessment of Disease Activity

    May Choi1, Emma Stevens2, Hongshu Guan2, Daniel Li3, Jack Ellrodt4, Benjamin Kargere4, Tianrun Cai2, Kazuki Yoshida5, Brendan Everett2 and Karen Costenbader6, 1Brigham and Women's Hospital | Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2Brigham and Women's Hospital, Boston, MA, 3Harvard, Columbus, OH, 4Williams College, Williamstown, 5Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 6Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: The risk of cardiovascular disease (CVD), including myocardial infarction and stroke, is higher in SLE than in the general population. The excess risk of…
  • Abstract Number: 1281 • ACR Convergence 2020

    Opioid-Related Encounters as a Predictor of 30-Day Readmissions in Lupus

    Christie Bartels1, Maria Schletzbaum2, Yi Chen3 and Amy Kind4, 1University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI, 2University of Wisconsin-Madison School of Medicine and Public Health, Department of Population Health Sciences, Madison, WI, 3University of Wisconsin School of Medicine and Public Health, Department of Biostatistics and Medical Informatics, Madison, WI, 4University of Wisconsin-Madison School of Medicine and Public Health, Department of Medicine, Health Services and Care Research Program, Geriatrics Division, Madison, WI

    Background/Purpose: One in four Medicare hospitalizations with systemic lupus erythematosus (SLE) results in readmission within 30 days, with “injuries and poisonings” as the second most…
  • Abstract Number: 1292 • ACR Convergence 2020

    Frequency and Predictors of Influenza Vaccine Hesitancy in Systemic Autoimmune Rheumatic Diseases

    Valeria Valerio1, Mariana Useche1, Mianbo Wang2, Sasha Bernatsky3, Christian Pineau4 and Ines Colmegna1, 1The Research Institute of the McGill University Health Centre, Montreal, Canada, 2Lady Davis institute for Medical Research, Montreal, QC, Canada, 3The Research Institute of the McGill University Health Centre, Montreal, ON, Canada, 4McGill University Health Center, Montreal, QC, Canada

    Background/Purpose: Patients with systemic autoimmune rheumatic diseases (SARDs) benefit from getting annual inactivated influenza vaccine (IIV). However, vaccine uptake among SARDs is suboptimal.  The delay…
  • Abstract Number: 1289 • ACR Convergence 2020

    Sex Differences in Mental Health and Quality of Life and Their Impact in the Treatment of Patients with Systemic Lupus Erythematosus

    Lilian Cano-Cruz1, Eduardo Aguirre-Aguilar1, Martín Valdez-López2, Ana Barrera-Vargas1, Virginia Pascual Ramos1 and Javier Merayo-Chalico3, 1INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Mexico City, Distrito Federal, Mexico, 2INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Mexico City, Mexico, 3INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION SALVADOR ZUBIRAN, Ciudad de Mexico, Distrito Federal, Mexico

    Background/Purpose: Systemic lupus erythematosus (SLE) predominantly affects young women. It is usually more aggressive in men and carries a worse prognosis. Information about gender differences…
  • Abstract Number: 1284 • ACR Convergence 2020

    Application of a Novel Method for Determination of Muscle Mass Relative to Fat Mass in Women with Systemic Lupus Erythematosus and Association with Disability

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Patients with SLE are at risk for both skeletal muscle loss and increased adiposity, which may predispose to worse health-related quality of life. Decreased…
  • Abstract Number: 1176 • ACR Convergence 2020

    Identifying Targets to Improve the Assessment of Psychosocial Risk Factors in Adolescent Patients: Perspectives from Pediatric Rheumatology Fellows in the United States and Canada

    Jacob Spitznagle1, Nayimisha Balmuri1, Alexa Adams1, Karen Onel2, Sarah Taber1 and Nancy Pan1, 1Hospital for Special Surgery, New York, NY, 2Pediatric Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Adolescent patients cared for in the pediatric rheumatology clinic balance challenges related to psychosocial stressors and physical growth with the complexities of living with…
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