ACR Meeting Abstracts

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  • Abstract Number: 103 • 2026 Pediatric Rheumatology Symposium

    Anifrolumab Use in Youngsters with Rheumatic Conditions: Case Series and a Review of the Evidence Base

    Madison Hoenle1, Kelly Wise2 and Shoghik Akoghlanian3, 1Nationwide Children's Pediatric Residency, Columbus, OH, 2Nationwide Children's Hospital, Hilliard, OH, 3Nationwide Childrens Hospital, Columbus, OH

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease that poses unique diagnostic and therapeutic challenges in children, given they experience more severe…
  • Abstract Number: 079 • 2026 Pediatric Rheumatology Symposium

    Still’s Disease Associated Lung Disease: Update From the European Registry

    Claudia Bracaglia1, Francesca Minoia2, Christoph Kessel3, Sebastiaan Vastert4, Manuela Pardeo5, Alessia Arduini5, Sarka Horackova Fingerhutova6, Irina Nikishina7, Ozge Basaran8, Nural Kiper8, Konstantin Belozerov9, Mikhail Kostik9, Sezgin Sahin10, Mia Glerup11, Roberta Caorsi12, AnnaCarin Horne13, Giovanni Filocamo14, Helmut Wittkowski15, Marija Jelusic16, Jordi Anton17, Samira Khaldi-Plassart18, Alexandre Belot18, Gerd Horneff19, Seraina Palmer Sarott20, Elvira Cannizzaro Schneider20, Lampros Fotis21, Serena Pastore22, Aurelia Calin23, Isabelle Kone-Paut24, Ozgur Kasapcopur10, Pavla Dolezalova6, Seza zen25, Angelo Ravelli26 and Fabrizio De Benedetti27, 1Division of Rheumatology Ospedale Pediatrico Bambino Gesu' IRCCS, Roma, Italy, Rome, Rome, Italy, 2Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Milan, Italy,, Milano, Italy, 3Department of Pediatric Rheumatology & Immunology, WWU Medical Center (UKM), Münster, Germany, Munster, Germany, 4University Medical Center Utrecht, Utrecht, Netherlands, 5Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, 6Centre for Paediatric Rheumatology and Autoinflammatory Diseases, Department of Paediatrics and Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic, Prague, Czech Republic, 7V.A. Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, Moscow, Russia, 8Department of Pediatrics, Hacettepe University, Ankara, Türkiye, Ankara, Turkey, 9Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russian Federation, Saint-Petersburg, Russia, 10Istanbul University-Cerrahpasa, Department of Pediatric Rheumatology, Istanbul, Türkiye, Istanbul, Turkey, 11Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, 12Department of Pediatrics and Rheumatology, IRRCS Istituto G. Gaslini, Genova, Italy, Genova, Italy, 13Department of pediatric rheumathology, Karolinska University Hospital and Department of pediatrics, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, 14Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Milan, Italy, Milano, Italy, 15Department of Pediatric Rheumatology & Immunology, WWU Medical Center (UKM), Münster, Germany, Munster, Italy, 16Department of Pediatrics, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia, Zagreb, Croatia, 17Pediatric Rheumatology, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain, Barcelona, Spain, 18Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France, Lyon, France, 19University Hospital of Cologne, Sankt Augustin, Germany, 20Department of Pediatric Rheumatology, University Children’s Hospital Zurich, Zurich, Switzerland, Zurich, Switzerland, 21Pediatric Rheumatology Division, 3rd Department of Pediatrics, National and Kapodistrian University of Athens,‘’ATTIKON’’ General University Hospital, Athens, Greece, Athens, Greece, 22IRCCS Burlo Garofolo, Trieste, Trieste, Italy, 23Marie Curie Children's Emergency Hospital, Bucharest, Romania, Bucharest, Romania, 24Pediatric rheumatology department, CEREMAIA Bicêtre hospital, APHP, Le Kremlin Bicêtre University of Paris Saclay, Paris, France, Paris, France, 25Hacettepe University Medical Faculty, Ankara, Turkey, 26IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genoa, Genoa, Italy, 27Bambino Gesu Children's Hospital, Rome, Rome, Italy

    Background/Purpose: Lung disease (LD) is an emerging severe life-threatening complication of Still’s Disease (SD) characterized by peculiar features. Patients with SD complicated by LD are…
  • Abstract Number: 099 • 2026 Pediatric Rheumatology Symposium

    Clinical Features of Juvenile Antisynthetase Syndrome: A Single-Center Case Series

    Joshua Marrs1, Maria Correa2, Manuel Silva-Carmona3 and Maria Pereira2, 1Baylor College of Medicine, MANVEL, TX, 2Baylor College of Medicine, Houston, TX, 3Texas Children's Hospital, TX

    Background/Purpose: Anti-synthetase syndrome (ASyS) is a rare autoimmune myopathy in children characterized by a triad of myositis, arthritis, and interstitial lung disease (ILD), though not all manifestations may be present at disease onset. Pediatric data remain limited, and disease…
  • Abstract Number: 001 • 2026 Pediatric Rheumatology Symposium

    Longitudinal Cardiovascular Profiles of Youth with Childhood-onset Systemic Lupus Erythematosus

    Joyce Chang1, Gabrielle Alonzi2, Michael Ferguson3, Andrea Knight4, Jane Newburger5, Pamela Weiss6, Mary Beth Son2 and Karen Costenbader7, 1Boston Children's Hospital, Newton, MA, 2Boston Children's Hospital, Boston, MA, 3Boston Children's Hospital, MA, 4Hospital for Sick Children, Toronto, ON, Canada, 5Boston Childen's Hospital, Boston, MA, 6Childrens Hospital of Philadelphia, Philadelphia, PA, 7Brigham and Women's Hospital/ Harvard Medical School, BOSTON, MA

    Background/Purpose: The cumulative impact of childhood-onset systemic lupus erythematosus (cSLE) on cardiovascular damage begins at disease onset. We sought to characterize longitudinal cardiovascular profiles of…
  • Abstract Number: 012 • 2026 Pediatric Rheumatology Symposium

    Prevalence and Impact of Adverse Childhood Experiences in Pediatric Systemic Lupus Erythematosus

    Anita Dhanrajani1, Rhea Bhargava2 and Alfred Kim3, 1Manning Family Children's Hospital, Tulane University, 2Tulane University Medicine, New Orleans, LA, 3Washington University School of Medicine, Saint Louis, MO

    Background/Purpose: Adverse childhood experiences (ACEs) have been linked to incident childhood-onset SLE (cSLE) and poorer patient-reported outcomes, raising the possibility that early-life stress may contribute…
  • Abstract Number: 045 • 2026 Pediatric Rheumatology Symposium

    Genotypes and Clinical Phenotypes of Monogenic Autoinflammatory Disorders in Michigan

    Ryan Mitacek1, Veronica Kwiatkowski1 and Basil Fathalla2, 1Children's Hospital of Michigan, Central Michigan University College of Medicine, 2Children's Hospital of Michigan, Detroit, MI

    Background/Purpose: Data regarding monogenic systemic autoinflammatory disorders (SAID) from the USA is scarce. Our study aims to report the spectrum of SAID and detail unique…
  • Abstract Number: 086 • 2026 Pediatric Rheumatology Symposium

    APOL1 Focal Segmental Glomerulosclerosis Requiring Renal Transplant, the Burden of Childhood onset Autoimmune and Autoinflammatory Disease

    Andrew Zeft1, Charles Kwon2, Raed Bou Matar2, Xiangling Wang2 and Sirada Panupattanapong1, 1Department of Pediatric Rheumatology, Cleveland Clinic Children's Hospital, Cleveland, OH, 2Cleveland Clinic

    Background/Purpose: Apolipoprotein L1 (APOL1) mediated kidney disease with focal segmental glomerulosclerosis (FSGS) is a severe form of renal disease with risk of progressing towards end…
  • Abstract Number: 041 • 2026 Pediatric Rheumatology Symposium

    Pediatric Behçet’s Disease: A 13-Year Single-Center Experience Highlighting Diagnostic Delays and High Neurological Burden

    Rasha Elrefai1, Andrea Ramirez1, Jamie Lai2, Cagri Yildirim-Toruner3, Eyal Muscal1 and Marietta DeGuzman1, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, The Woodlands, TX, 3Texas Children's Hospital/ Baylor College of Medicine, Houston, TX

    Background/Purpose: Behçet's disease (BD) is a systemic vasculitis primarily characterized by recurrent oral and genital aphthous ulceration. It is reported that 15-20% of all BD…
  • Abstract Number: 026 • 2026 Pediatric Rheumatology Symposium

    Treatment strategies for articular flares in JIA patients receiving biologic therapy

    Jonatan zalcman, Yoel Levinsky, Liora Harel, Ruth Livny and gil amarilyo, Schneider Children's medical center of Israel

    Background/Purpose: Biologic agents form the cornerstone of therapy for Juvenile Idiopathic Arthritis (JIA); however, the optimal management of flares that occur during ongoing treatment remains…
  • Abstract Number: 047 • 2026 Pediatric Rheumatology Symposium

    Association of anti-DFS70 with autoimmune diseases in children

    Sara Concha, Pontificia Universidad Católica de Chile

    Background/Purpose: The ANA 23 panel is widely requested in patients with positive ANA to guide their association with autoimmune diseases; however, the anti-DFS70 antibody has…
  • Abstract Number: 090 • 2026 Pediatric Rheumatology Symposium

    Characterizing CNS MRI Abnormalities in Pediatric ANCA-Associated Vasculitis

    Dawn Gist1, Eyal Muscal2, Srikala Narayanan3 and Divya Thomas4, 1Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine, houston, TX, 3Texas Children's Hospital Division of Neuroradiology, 4Baylor College of Medicine/Texas Children's Hospital

    Background/Purpose: CNS involvement in pediatric ANCA-associated vasculitis (AAV) is rare but can lead to significant neurological symptoms, including headaches, seizures, behavioral changes, and occasional cerebrovascular…
  • Abstract Number: 036 • 2026 Pediatric Rheumatology Symposium

    Giant Aneurysms in Kawasaki Disease: A Large Quarternary Single Center Experience

    Meredith Rae1, Jessica Nguyen2, Olivia Kwan3, Duc Nguyen4 and Cagri Yildirim-Toruner5, 1Baylor College of Medicine/Texas Children's Hospital, 2Cook Children's Hospital, 3Baylor College of Medicine; Texas Children's Hospital, 4Baylor College of Medicine, 5Texas Children's Hospital/ Baylor College of Medicine, Houston, TX

    Background/Purpose: Kawasaki disease (KD) is an acute medium-vessel vasculitis predominantly affecting children younger than five years old. It is the most common cause of acquired…
  • Abstract Number: 104 • 2026 Pediatric Rheumatology Symposium

    Identification of Joints with Active Arthritis from Clinical Notes with High Fidelity using a Large Language Model

    Marc Natter1, Seungwon Lee2, Min-Lee Chang3 and Mei-Sing Ong1, 1Boston Children's Hospital, Boston, MA, 2Boston Children's Hospital, 3Boston Children's Hospital, MA

    Background/Purpose: Accumulating evidence supports a new, biology-driven classification system for JIA diagnosis and prognosis, depending upon identification of patterns of arthritis involvement, rather than just…
  • Abstract Number: 093 • 2026 Pediatric Rheumatology Symposium

    HOW DO WE HANDLE STILL’S DISEASE? REAL-LIFE CLINICIANS’ CHOICES FROM THE METAPHOR PROJECT WORLDWIDE SURVEY

    Francesco Baldo1, Greta Rogani2, Claudia Bracaglia3, Dirk Foell4, Marco Gattorno5, Jordi Anton6, Marija Jelusic7, Paul Brogan8, Scott Canna9, Randy Cron10, Fabrizio De Benedetti11, Alexei Grom12, Merav Heshin Bekenstein13, AnnaCarin Horne14, Raju Khubchandani15, Mao Mizuta16, Seza zen17, Pierre Quartier Dit Maire18, Angelo Ravelli19, Nicolino Ruperto20, Masaki Shimizu21, Grant Schulert12, Rashmi Sinha22, Christiaan Scott23, Joost Swart24, Bruno Fautrel25, Sebastiaan Vastert2 and Francesca Minoia26, 1UOC Reuamtologia Pediatrica-ASST-Pini-CTO.it, Italy, 2University Medical Center Utrecht, Utrecht, Netherlands, 3Division of Rheumatology Ospedale Pediatrico Bambino Gesu' IRCCS, Roma, Italy, Rome, Rome, Italy, 4University Hospital Muenster, Muenster, Germany, 5Division of Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genova, Italy, 6Hospital Sant Joan de Du. Universitat de Barcelona, Esplugues de Llobregat (Barcelona), Spain, 7University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Zagreb, Croatia, 8UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom, 9Children's Hospital of Philadelphia, Philadelphia, PA, 10University of Alabama at Birmingham, Birmingham, AL, 11Bambino Gesu Children's Hospital, Rome, Rome, Italy, 12Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 13Tel Aviv Medical Center Israel, Binyamina, Israel, 14Karolinska University Hospital, Sollentuna, Sweden, 15SRCC Children's Hospital, Mumbai, India, India, 16Department of Paediatric Rheumatology, Hyogo Prefectural Kobe Children's Hospital, Kanazawa, Japan, Kanazawa, Japan, 17Hacettepe University Medical Faculty, Ankara, Turkey, 18Necker hospital, Paris Cedex 15, France, 19IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genoa, Genoa, Italy, 20Università Milano Bicocca and Fondazione IRCSS S. Gerardo dei Tintori, Monza, Italy, 21Tokyo Medical and Dental University, Tokyo, Japan, Kanazawa, Japan, 22Systemic JIA Foundation, Los Altos, CA, 23Childrens Hospital of Eastern Ontario (CHEO), Ottawa, ON, Canada, 24Wilhelmina Children's Hospital / UMC Utrecht, Utrecht, Netherlands, 25Sorbonne University - APHP, Paris, France, 26Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy

    Background/Purpose: Despite continuous improvement in care and the recent update of international recommendations, relevant discrepancies in the approach to Still’s disease (SD) still exists.The study…
  • Abstract Number: 106 • 2026 Pediatric Rheumatology Symposium

    Clinical Characteristics and Safety Outcomes in Refractory Kawasaki Disease Treated with Second-Dose Infliximab

    Mariia Pavlenko1, Kathryn Scheinberg2, Adam Bartholomeo3, Samuel Lazaroff4, Carla Levin2, Kira Frappa5, Matthew Miller5, Denise Vidas5, Marsha Anderson5, Samuel Dominguez5 and Lyndsey Cole6, 1University of Colorado Anschutz Medical Campus, Department of Pediatrics, 2University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Rheumatology, 3University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Rheumatology and Section of Allergy/Immunology, 4University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Rheumatology;University of Colorado Anschutz Medical Campus, Department of Medicine, Section of Rheumatology, 5University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Infectious Diseases & Epidemiology, 6University of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of RheumatologyUniversity of Colorado Anschutz Medical Campus, Department of Pediatrics, Section of Infectious Diseases & Epidemiology

    Background/Purpose: Infliximab is an effective treatment for Kawasaki Disease (KD) as part of intensified initial therapy in combination with intravenous immunoglobulin (IVIG) or as a…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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