ACR Meeting Abstracts

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  • Abstract Number: 052 • 2026 Pediatric Rheumatology Symposium

    Case Series: Treatment of Refractory Lung Disease in Systemic Juvenile Idiopathic Arthritis with Cyclophosphamide and Rituximab Combination Therapy

    William Freeman1, Randy Cron2 and Eileen Rife3, 1Zucker School of Medicine at Hofstra University, Bellerose, NY, 2University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama Birmingham, Vestavia Hills, AL

    Background/Purpose: Systemic juvenile idiopathic arthritis-associated lung disease (sJIA-LD) is a rare, potentially fatal complication of sJIA, often accompanied by pulmonary hypertension (PH) and macrophage activation…
  • Abstract Number: 050 • 2026 Pediatric Rheumatology Symposium

    The Quiet Beginning: Early Pediatric Systemic Lupus Erythematosus (SLE) Without Nephritis and the Path to Renal Involvement

    Tara McGrath1, Dax Rumsey1, Lillian Lim1 and Audrea Chen2, 1University of Alberta, Edmonton, AB, Canada, 2Stollery Children's Hospital, Edmonton, AB, Canada

    Background/Purpose:   It is well known that patients with juvenile Systemic Lupus Erythematosus (jSLE) are at much higher risk of developing Lupus Nephritis (LN) compared…
  • Abstract Number: 079 • 2026 Pediatric Rheumatology Symposium

    Still’s Disease Associated Lung Disease: Update From the European Registry

    Claudia Bracaglia1, Francesca Minoia2, Christoph Kessel3, Sebastiaan Vastert4, Manuela Pardeo5, Alessia Arduini5, Sarka Horackova Fingerhutova6, Irina Nikishina7, Ozge Basaran8, Nural Kiper8, Konstantin Belozerov9, Mikhail Kostik9, Sezgin Sahin10, Mia Glerup11, Roberta Caorsi12, AnnaCarin Horne13, Giovanni Filocamo14, Helmut Wittkowski15, Marija Jelusic16, Jordi Anton17, Samira Khaldi-Plassart18, Alexandre Belot18, Gerd Horneff19, Seraina Palmer Sarott20, Elvira Cannizzaro Schneider20, Lampros Fotis21, Serena Pastore22, Aurelia Calin23, Isabelle Kone-Paut24, Ozgur Kasapcopur10, Pavla Dolezalova6, Seza zen25, Angelo Ravelli26 and Fabrizio De Benedetti27, 1Division of Rheumatology Ospedale Pediatrico Bambino Gesu' IRCCS, Roma, Italy, Rome, Rome, Italy, 2Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Milan, Italy,, Milano, Italy, 3Department of Pediatric Rheumatology & Immunology, WWU Medical Center (UKM), Münster, Germany, Munster, Germany, 4University Medical Center Utrecht, Utrecht, Netherlands, 5Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Lazio, Italy, 6Centre for Paediatric Rheumatology and Autoinflammatory Diseases, Department of Paediatrics and Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic, Prague, Czech Republic, 7V.A. Nasonova Research Institute of Rheumatology, Moscow, Russian Federation, Moscow, Russia, 8Department of Pediatrics, Hacettepe University, Ankara, Türkiye, Ankara, Turkey, 9Saint-Petersburg State Pediatric Medical University, Saint-Petersburg, Russian Federation, Saint-Petersburg, Russia, 10Istanbul University-Cerrahpasa, Department of Pediatric Rheumatology, Istanbul, Türkiye, Istanbul, Turkey, 11Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, 12Department of Pediatrics and Rheumatology, IRRCS Istituto G. Gaslini, Genova, Italy, Genova, Italy, 13Department of pediatric rheumathology, Karolinska University Hospital and Department of pediatrics, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, 14Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Milan, Italy, Milano, Italy, 15Department of Pediatric Rheumatology & Immunology, WWU Medical Center (UKM), Münster, Germany, Munster, Italy, 16Department of Pediatrics, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia, Zagreb, Croatia, 17Pediatric Rheumatology, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain, Barcelona, Spain, 18Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France, Lyon, France, 19University Hospital of Cologne, Sankt Augustin, Germany, 20Department of Pediatric Rheumatology, University Children’s Hospital Zurich, Zurich, Switzerland, Zurich, Switzerland, 21Pediatric Rheumatology Division, 3rd Department of Pediatrics, National and Kapodistrian University of Athens,‘’ATTIKON’’ General University Hospital, Athens, Greece, Athens, Greece, 22IRCCS Burlo Garofolo, Trieste, Trieste, Italy, 23Marie Curie Children's Emergency Hospital, Bucharest, Romania, Bucharest, Romania, 24Pediatric rheumatology department, CEREMAIA Bicêtre hospital, APHP, Le Kremlin Bicêtre University of Paris Saclay, Paris, France, Paris, France, 25Hacettepe University Medical Faculty, Ankara, Turkey, 26IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genoa, Genoa, Italy, 27Bambino Gesu Children's Hospital, Rome, Rome, Italy

    Background/Purpose: Lung disease (LD) is an emerging severe life-threatening complication of Still’s Disease (SD) characterized by peculiar features. Patients with SD complicated by LD are…
  • Abstract Number: 007 • 2026 Pediatric Rheumatology Symposium

    Subtle Signs, Severe Consequences: Clinical profile of infants with giant coronary aneurysms compared to those with normal coronaries. A multicentric retrospective analysis of infants with Kawasaki disease

    Abhay Shivpuri1, manjari Agarwal2 and sujata Sawhney3, 1Neoclinic Children's Hospital, Jaipur, Rajasthan, India, 2Sir Ganga Ram Hospital, NEW DELHI, Delhi, India, 3Sir Ganga Ram Hospital, Sector 37 noida, Uttar Pradesh, India

    Background/Purpose: Kawasaki disease (KD) is a systemic medium vessel vasculitis that is predominantly a clinical diagnosis as defined by the American Heart Association (AHA). KD…
  • Abstract Number: 082 • 2026 Pediatric Rheumatology Symposium

    Ophthalmic Predictors of Response to Methotrexate Monotherapy in Pediatric Non-Infectious Uveitis

    Abigale Jagger1, Emaan Asghar2, Megan Quinlan-Waters3, Alexandra Duell4, Mekibib Altaye5, Virginia Miraldi Utz4 and Sheila Angeles-Han6, 1Cincinnati Children's, Cincinnati, OH, 2Self, 3Cincinnati Children's Hospital Medical Center, 4Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Cincinnati Children's Hospital, Cincinnati, 6Cincinnati Children's Hospital, Cincinnati, OH

    Background/Purpose: Children with chronic, non-infectious uveitis (NIU) often require systemic, steroid-sparing therapy to control inflammation and prevent vision-threatening complications. Methotrexate (MTX) is the first-line systemic…
  • Abstract Number: 078 • 2026 Pediatric Rheumatology Symposium

    Development of A High-Parameter Whole Blood Thrombo-inflammation Flow Cytometry Panel for Research in Pediatric Autoimmune Diseases

    Yuxuan Zhen1, Benjamin Tourdot2, Xiang Zhang3, Donald Lynch3 and Ekemini Ogbu1, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, 3University of Cincinnati

    Background/Purpose: Platelets are emerging as key modulators and protagonists of aberrant immune responses in severe systemic autoimmune diseases like systemic lupus erythematosus (SLE). While the…
  • Abstract Number: 045 • 2026 Pediatric Rheumatology Symposium

    Genotypes and Clinical Phenotypes of Monogenic Autoinflammatory Disorders in Michigan

    Ryan Mitacek1, Veronica Kwiatkowski1 and Basil Fathalla2, 1Children's Hospital of Michigan, Central Michigan University College of Medicine, 2Children's Hospital of Michigan, Detroit, MI

    Background/Purpose: Data regarding monogenic systemic autoinflammatory disorders (SAID) from the USA is scarce. Our study aims to report the spectrum of SAID and detail unique…
  • Abstract Number: 049 • 2026 Pediatric Rheumatology Symposium

    Novel Insights of Brain MRI Features in Neonatal Lupus Erythematosus with Hydrocephalus

    Sirada Panupattanapong and Andrew Zeft, Department of Pediatric Rheumatology, Cleveland Clinic Children's Hospital, Cleveland, OH

    Background/Purpose: Neurologic manifestations in neonatal lupus erythematosus (NLE) are rare and remain poorly characterized. Macrocephaly and hydrocephalus have been reported in approximately 10% of cases,…
  • Abstract Number: 087 • 2026 Pediatric Rheumatology Symposium

    A Growing Problem: Factors Associated with Growth Disturbances in Juvenile Localized Scleroderma

    Bona Paek1 and Suzanne Li2, 1Hackensack Meridian School of Medicine, 2Joseph M. Sanzari Children's Hospital, Hackensack Meridian SOM, Hackensack, NJ

    Background/Purpose: Juvenile localized scleroderma (jLS) is a chronic autoimmune, fibrosing condition associated with a high burden of damage, including functional impairment. Severe morbidity most often…
  • Abstract Number: 081 • 2026 Pediatric Rheumatology Symposium

    Therapeutic Drug Monitoring in Pediatric Rheumatology: A Survey of Providers in North America

    A. Carmela Sagcal-Gironella1, Rachel Randell2, Hermine Brunner3, Ellen Go4, Anita Siu5, Ruud Verstegen6 and Marietta DeGuzman7, 1Hackensack University Medical Center, Hackensack, NJ, 2Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Emory University/Children Healthcare of Atlanta, GA, 5Rutgers University, Ernest Mario School of Pharmacy and Jersey Shore University Medical Center and K. Hovnanian Children's Hospital, Piscataway, NJ, 6The Hospital for Sick Children, Toronto, ON, Canada, 7Baylor College of Medicine, Houston, TX

    Background/Purpose: Therapeutic drug monitoring (TDM) can optimize patient outcomes in pediatric rheumatology, but its use is not standardized. This study aimed to explore TDM practice…
  • Abstract Number: 060 • 2026 Pediatric Rheumatology Symposium

    Impact of Social Determinants of Health on Outcomes in Pediatric Uveitis

    erin stahl1, ashley lytch2, Janelle Noel-Macdonnell2 and ashley cooper1, 1Children's Mercy Kansas City, Kansas City, MO, 2Children's Mercy Kansas City

    Background/Purpose: Chronic uveitis is an immune-mediated disease that can cause severe complications, including blindness. Chronic uveitis care involves numerous medical visits, frequent laboratory monitoring and…
  • Abstract Number: 071 • 2026 Pediatric Rheumatology Symposium

    The Association Between Age at Diagnosis and Health-Related Quality of Life in Takayasu Arteritis

    Jessica Bloom1, Kaci Pickett-Nairne2, Lori Silveira2, Cristina Burroughs3, Katrina Bargender4, Amy Bolton5, Christine Yeung6, Jennifer Gordon5, Peter A. Merkel7 and Karen James8, 1University of Colorado Aurora, CO, 2University of Colorado, 3University of South Florida, 4Vasculitis Patient-Powered Research Network, Caledonia, WI, 5Vasculitis Patient-Powered Research Network, 6University of Pennsylvania, 7University of Pennsylvania, Philadelphia, United Kingdom, 8University of Utah, Salt Lake City, UT

    Background/Purpose: Takayasu arteritis (TAK) can occur throughout the lifespan and impacts health-related quality of life (HRQoL). This study examined the relationship between age at diagnosis…
  • Abstract Number: 062 • 2026 Pediatric Rheumatology Symposium

    Evaluating the Relationship Between an Electronic Transition Planning Tool and Transition Success in a Pediatric Rheumatology Clinic

    Karissa Chesky1, Kyla Blasingame1, Jimin Kim1, Charles Lee2, Alonzo Needum1, Miriah Gillispie-Taylor3 and Tiphanie Vogel4, 1Baylor College of Medicine, 2Baylor College of Medicine, Houston, TX, 3Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 4Baylor College of Medicine/Texas Children's Hospital

    Background/Purpose: Young adults with chronic health conditions deserve an intentional transition from pediatric to adult care. We have developed a longitudinal process to standardize transfer…
  • Abstract Number: 024 • 2026 Pediatric Rheumatology Symposium

    Therapeutic Plasma Exchange in Pediatric Autoimmune Encephalitis

    Ingrid Kattan1, PAOLA LARA HERERA2, ENRIQUE FAUGIER FUENTES3, Candy Leon, MD3, Andrea Sanchez3, VIanca De Leon3 and Enrique Juarez3, 1HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ, Ciudad de Mxico, Mexico, 2HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ, MEXICO CITY, Mexico, 3HOSPITAL INFANTIL DE MEXICO FEDERICO GOMEZ

    Background/Purpose: Autoimmune encephalitis (AE) is a severe neuroinflammatory disorder mediated by antibodies against neuronal receptors. Therapeutic plasma exchange (TPE) can remove autoantibodies, immune complexes, and…
  • Abstract Number: 003 • 2026 Pediatric Rheumatology Symposium

    Dysregulated Macrophage–Fibroblast Crosstalk Identified by Single-Cell RNA-seq in Juvenile Systemic Scleroderma Skin

    Aneri Shethji1, Theresa Hutchins1, Anwesha Sanyal1 and Kathryn Torok2, 1UPMC Childrens Hospital of Pittsburgh, 2University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Juvenile systemic scleroderma (jSSc) is a rare autoimmune disease characterized by progressive fibrosis and vascular dysfunction. Although jSSc shares important clinical features with adult…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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