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  • Abstract Number: 1491 • ACR Convergence 2022

    Clinically Relevant Differences in the Mobility of Patients with Axial Spondyloarthritis Related to Daytime of Performance

    David Kiefer1, Juergen Braun1, Lucia Schneider1, Niklas Kolle1, Uta Kiltz1, Ioana Andreica2, Philipp Sewerin1, Bjoern Buehring3, susanne herbold1 and Xenofon Baraliakos4, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-Universität-Bochum, Herne, Germany, 3Bergisches Rheuma-Zentrum, Velbert, Germany, 4Rheumazentrum Ruhrgebiet Herne, Herne, Germany

    Background/Purpose: Patients with axial spondyloarthritis (axSpA) often experience impairments of spinal mobility and physical function due to inflammation and structural damage. Back pain and morning…
  • Abstract Number: 1503 • ACR Convergence 2022

    Is Inflammation-driven Bone Loss Associated with Two-year Bone Formation at the Same Vertebra in Axial Spondyloarthritis? – a Multilevel MRI and Low Dose CT Analysis from the Sensitive Imaging of Axial Spondyloarthritis (SIAS) Cohort

    Mary Lucy Marques1, Nuno Pereira da Silva2, Désirée van der Heijde3, Rosalinde Stal4, Xenofon Baraliakos5, Juergen Braun6, Monique Reijnierse4, Caroline Bastiaenen7, Sofia Ramiro4 and floris van Gaalen4, 1Leiden University Medical Center, Coimbra, Portugal, 2Radiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 3Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 4Leiden University Medical Center, Leiden, Netherlands, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6Rheumazentrum Ruhrgebiet, Herne, Germany, 7Department of Epidemiology, Maastricht University, Maastricht, Netherlands

    Background/Purpose: In radiographic axial spondyloarthritis (r-axSpA), inflammation-driven trabecular bone loss is hypothesised to trigger bone repair at an anatomically distinct site of the same vertebra…
  • Abstract Number: 1504 • ACR Convergence 2022

    Efficacy of Risankizumab in the Treatment of PsA Patients with Limited and Extensive Joint Involvement

    Alexis Ogdie1, Christopher Ritchlin2, Priscila Nakasato3, Ran Liu4, Christian Kaufmann4, Byron Padilla5 and Laure Gossec6, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, 3AbbVie Inc, Toronto, ON, Canada, 4AbbVie, Inc., North Chicago, IL, 5AbbVie, Inc., Waukegan, IL, 6Sorbonne Université, Paris, France

    Background/Purpose: PsA is a systemic disease involving multiple domains. Peripheral joints are frequently affected, and patients often initially present with asymmetrical oligoarthritis (2-4 swollen joints).…
  • Abstract Number: 1494 • ACR Convergence 2022

    Determinants of Clinically Important Worsening in Early Axial Spondyloarthritis: Analysis of the DESIR Cohort over 5 Years

    Faten Hamitouche1, Sushmitha Kumaradev1, Désirée van der Heijde2, Sofia Ramiro3, Alexandre Sepriano4 and Anna Molto5, 1INSERM U-1153, Université Paris-Cité, CRESS, Paris, France, 2Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands, 4Leiden University Medical Centre, Portela Loures, Portugal, 5Rheumatology Department, Hôpital Cochin,Assistance Publique- Hôpitaux de Paris, Paris, France

    Background/Purpose: A definition for clinically important worsening (CIW) of axial Spondyloarthritis (axSpA) has been proposed by ASAS: i.e. an increase of ≥0.9 points of ASDAS.…
  • Abstract Number: 1502 • ACR Convergence 2022

    Assessment of Perceptions and Practices Regarding the Collaborative Management of Patients with Psoriatic Arthritis Among US Dermatology and Rheumatology Teams

    Evan Siegel1, Amit Garg2, Jeffrey Carter3, Laura Simone4 and Marykate Nelson5, 1Georgetown University School of Medicine, Washington, DC, 2Zucker School of Medicine at Hofstra/Northwell, Lake Success, NY, 3PRIME Education, Boynton Beach, FL, 4PRIME Education, Omaha, NE, 5PRIME Education, Drexel Hill, PA

    Background/Purpose: The optimal care of psoriatic arthritis (PsA) requires effective collaboration between rheumatology and dermatology teams. We executed an initiative to identify gaps and inform…
  • Abstract Number: 1515 • ACR Convergence 2022

    Assessing the Difference Between Radiographic Axial Spondylorthritis and Non-radiographic Axial Spondylorthritis in a Two-center Descriptive Study with Mexican Patients: The Influence of Clinical, Demographic, Laboratory and Clinimetric Features

    John Londono1, Gustavo Rodriguez-Salas2, Igor Rueda-Cardenas3, Ana Maria Santos1, Marta Mantilla1, Juan Camilo Santacruz2, Cesar Pachecho4, Gilberto Vargas-Alarcon5 and Ruben Burgos vargas6, 1Spondyloarthropathies study group - Universidad de La Sabana - Hospital Militar Central, Bogotá, Colombia, 2Spondyloathropathies study group Universidad de La Sabana Hospital Militar Central, Bogotá, Colombia, 3Spondyloarthropathies study group - Universidad de LA Sabana - Hospital Militar Central, Colombia, Colombia, 4Universidad Autónoma de chihuahua, Chihuahua, Mexico, 5Insituto Nacional de Cardiología Ignacio Chavez, Ciudad de México, Mexico, 6hospital general de mexico, Ciudad de México, Mexico

    Background/Purpose: Spondyloarthritis (SpA) is a group of inflammatory rheumatic diseases that have some key features in common. According to ASAS, this condition is classified into…
  • Abstract Number: 1509 • ACR Convergence 2022

    Patient Clusters Identified by Machine Learning from a Pooled Analysis of the Clinical Development Program of Secukinumab in Psoriatic Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis with Axial Manifestations

    Xenofon Baraliakos1, Effie Pournara2, Dafna Gladman3, Philip J Mease4, Samad S Jahandideh2 and Laura Coates5, 1Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 2Novartis Pharma AG, Basel, Switzerland, 3Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, 4Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 5Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom

    Background/Purpose: Universally acceptable clinical and imaging criteria to define axial psoriatic arthritis (PsA) is lacking.1 Machine learning (ML) algorithms can detect patterns from large clinical…
  • Abstract Number: 1511 • ACR Convergence 2022

    Is There a Correlation Between Skin and Musculoskeletal Activity in Psoriatic Arthritis

    Dafna Gladman1, Ghaydaa Aldabie2, Fangya Ma3, Mitchell Sutton4, Ker-Ai Lee3 and Richard Cook3, 1Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, 2Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, 3University of Waterloo, Waterloo, ON, Canada, 4Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

    Background/Purpose: The majority of patients with PsA present with skin manifestations first. Several studies have examined the relationship between activity/severity of skin and joint manifestations,…
  • Abstract Number: 1507 • ACR Convergence 2022

    Diagnostic Delay of More Than 6 Months Contributes to Poor Patient-Reported Outcome Measures in Psoriatic Arthritis

    Neel Tapryal1, George Gondo2, M. Elaine Husni3, Alice Gottlieb4 and Joseph Merola5, 1Cleveland Clinic, Rocky River, OH, 2National Psoriasis Foundation, Portland, OR, 3Cleveland Clinic, Cleveland, OH, 4Department of Dermatology, The Icahn School of Medicine at Mount Sinai, New York, NY, 5Harvard Medical School, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Psoriatic arthritis (PsA) is a type of inflammatory arthritis in which the time between symptom onset and a diagnosis of PsA is highly variable.…
  • Abstract Number: 1518 • ACR Convergence 2022

    Prevalence, Risk Factors and Treatment Patterns of Digital Ischemic Complications in Systemic Sclerosis: A Single Center Cross-Sectional Study

    Ashima Makol1, Alicia Hinze2, Rachel Giblon1, Yasser Radwan3, Tina Gunderson4, David Liedl1, Kenneth J. Warrington4, Cynthia Crowson5 and Paul Wennberg1, 1Mayo Clinic, Rochester, MN, Rochester, MN, 2Mayo Clinic - Rochester, MN, Rochester, MN, 3Mayo Clinic/ Michigan State University, Lansing, MI, 4Mayo Clinic, Rochester, MN, 5Mayo Clinic, Eyota, MN

    Background/Purpose: Digital ischemic complications (DICs, including digital ulcers, digital pitting/scars, gangrene and/or amputation) can significantly impact hand function, disability and overall prognosis in SSc. We…
  • Abstract Number: 1517 • ACR Convergence 2022

    Value of the Anti-CD74 Antibodies for the Diagnosis of Axial Spondyloarthritis: Results of a Prospective Study in Patients with Suspicious Low Back Pain

    Nelly Ziade1, Avin Maroof2, Antonella Abi Najm1, Torsten Witte3 and Xenofon Baraliakos4, 1Saint-Joseph University, Beirut, Lebanon, 2Rizgary Teaching Hospital - Erbil, Erbil, Iraq, 3MH-Hannover, Hannover, Germany, 4Rheumazentrum Ruhrgebiet Herne, Herne, Germany

    Background/Purpose: Patients with axial spondyloarthritis (axSpA) are diagnosed late, partially due to the absence of a reliable biomarker. The diagnostic value of the anti-CD74 antibodies…
  • Abstract Number: 1519 • ACR Convergence 2022

    Using Galacetin-3 (Gal-3) and Cardiotrophin-1 (CT-1) for Early Detection of Primary Heart Involvement in Systemic Sclerosis as Seen on Cardiac MRI

    Erin Chew1, Sarah Wood1, Bibin Varghese1, Christopher Chew2, erin wilfong1 and Tracy Frech1, 1Vanderbilt University Medical Center, Nashville, TN, 2University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Primary heart involvement in systemic sclerosis (SSc-pHI) is characterized by myocardial inflammation with resultant fibrosis that is not secondary to ischemic heart disease or…
  • Abstract Number: 1461 • ACR Convergence 2022

    The Frequency of Systemic Lupus Erythematosus in Patients with Immune Thrombocytopenic Purpura: A Systematic Meta-analysis

    Omer Pamuk1 and Sarfaraz Hasni2, 1NIH/NIAMS, Bethesda, MD, 2NIAMS/NIH, Bethesda, MD

    Background/Purpose: Immune thrombocytopenic purpura (ITP) is an organ-specific autoimmune disease and its etiopathogenetic mechanisms are suggestive of systemic autoimmune diseases (SAD) such as systemic lupus…
  • Abstract Number: 1410 • ACR Convergence 2022

    Subclinical Atherosclerosis Is Not Related with Acid Uric in Rheumatoid Arthritis: Study of 1005 Patients of a Single University Hospital

    Fabricio Benavides Villanueva1, Cristina Corrales1, Ivan Ferraz Amaro2, Nuria Vegas Revenga3, Ricardo Blanco4, Miguel Angel Gonzalez Gay5 and Alfonso Corrales6, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 3Hospital Galdakao- Usansolo, Galdakao, Spain, 4Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 5Hospital Universitario Marques de Valdecilla, Lugo, Spain, 6Research Group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain

    Background/Purpose: Rheumatoid Arthritis (RA) and Gout are related with increased cardiovascular (CV) disease. Carotid plaques and increased carotid intima-media thickness (cIMT) are surrogate markers of…
  • Abstract Number: 1266 • ACR Convergence 2022

    Time-course Ultrasonography to Predict Flare After Discontinuation of Biologics in Patients with Rheumatoid Arthritis Achieving Stringent Remission

    Takehisa Ogura1, Takaharu Katagiri2, Yuto Takakura3, Chihiro Imaizumi4 and Hideto Kameda4, 1Toho university, Meguro-ku, Japan, 2Toho University School of Medicine (Ohashi Medical Center), Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan, 3Toho University, Setagayaku, Japan, 4Toho University, Tokyo, Japan

    Background/Purpose: Ultrasonography (US) has been suggested to be useful in predicting flare in patients with rheumatoid arthritis (RA) after discontinuation of biological disease-modifying antirheumatic drugs…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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