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  • Abstract Number: 1046 • ACR Convergence 2022

    Scleroderma Heart Disease

    Mohamed Talaat1, Vivien Hsu2 and Daniel Shindler3, 1Rutgers Robert Wood Johnson University Hospital, North Brunswick, NJ, 2Rutgers-RWJ Medical School, South Plainfield, NJ, 3Rutgers Robert Wood Johnson University Hospital, New Brunswick, NJ

    Background/Purpose: Scleroderma heart involvement (SHI) is the 3rd leading cause of death in systemic sclerosis (SSc) [1] following interstitial lung disease (ILD) & pulmonary arterial…
  • Abstract Number: 1048 • ACR Convergence 2022

    Nailfold Capillaroscopy and Candidate Biomarker Levels in Systemic Sclerosis-associated Pulmonary Hypertension, Profiling of Non-invasive Markers: A Cross Sectional Study

    Jacqueline Lemmers1, Arjan van Caam2, Brigit Kersten2, Els Ende, van den2, Hanneke KNAAPEN2, Arie Dijk, van2, Wanda Hagmolen of ten Have2, Frank van den Hoogen2, Hans Koenen2, Sander van Leuven3, wynand Alkema4, Ruben Smeets2 and Madelon Vonk5, 1Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands, 2Radboudumc, Nijmegen, Netherlands, 3Radboud University, Nijmegen, Netherlands, 4Hanze University, Groningen the Netherlands, Dept. Data Science for Life Sciences & Health, Groningen, Netherlands, 5Department of Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands

    Background/Purpose: Pulmonary hypertension (PH) is one of the leading causes of death in Systemic Sclerosis (SSc). Early detection and treatment of PH in SSc is…
  • Abstract Number: 1060 • ACR Convergence 2022

    Clinical Characteristics and Prognosis of Patients with Systemic Sclerosis Sine Scleroderma: Data from the International EUSTAR Database

    Alain Lescoat1, Suiyuan Huang2, PATRICIA E CARREIRA3, Elise Siegert4, Jeska de Vries-Bouwstra5, Jörg Distler6, Vanessa Smith7, Branimir Anic8, Francesco Del Galdo9, Nemanja Damjanov10, Simona Rednic11, camillo Ribi12, Dominique Farge Bancel13, Anna-Maria Hoffmann-vold14, Armando Gabrielli15, Oliver Distler16, Dinesh Khanna17 and Yannick Allanore18, 1CHU Rennes - University Rennes 1, Rennes, France, 2University of Michigan, Ann Arbor, MI, 3HOSPITAL 12 DE OCTUBRE, Madrid, Spain, 4Charité Hospital, Berlin, Germany, 5Leiden University Medical Center, Leiden, Netherlands, 6Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany, 7Department of Rheumatology, Ghent University Hospital – Department of Internal Medicine, Ghent University, Belgium – Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Gent, Belgium, 8Clinical Hospital Centre Zagreb, School of Medicine, University of Zagreb, Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, Zagreb, Croatia, 9Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health and NIHR Biomedical Research Centre, University of Leeds, Leeds, United Kingdom, 10Institute of Rheumatology, Belgrade, Serbia, 11Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania, 12Service of Immunology and Allergy / CHUV, Lausanne, Switzerland, 13Saint Louis Hospital, Paris, France, 14Oslo University Hospital, Oslo, Norway, 15Università Politecnica delle Marche, Ancona, Italy, 16Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 17Division of Rheumatology, Department of Internal Medicine, Scleroderma Program, University of Michigan, Ann Arbor, MI, 18Department of Rheumatology A, Descartes University, APHP, Cochin Hospital, Paris, France, Paris, France

    Background/Purpose: This study aimed to characterise the main clinical features of patients with systemic sclerosis (SSc) sine scleroderma (ssSSc) in comparison with the limited cutaneous…
  • Abstract Number: 1059 • ACR Convergence 2022

    Vision Transformer Assisting Rheumatologists in Screening for Capillaroscopy Changes in Systemic Sclerosis: An Artificial Intelligence Solution

    Alexandru Garaiman1, Farhad Nooralahzadeh2, Carina Mihai1, Nikitas Gkikopoulos1, Nicolas Perez Gonzalez2, Mike Becker1, Oliver Distler1, Michael Krauthammer3 and Britta Maurer4, 1Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 2Department of Biomedical Informatics, University of Zurich, Zürich, Switzerland, 3Department of Quantitative Biomedicine, University of Zurich, Zürich, Switzerland, 4Department of Rheumatology and Immunology, University Hospital Bern, University of Bern, Bern, Switzerland

    Background/Purpose: An accurate assessment of nailfold capillaroscopy (NFC) images has great importance in the diagnosis and prognosis of systemic sclerosis (SSc). To overcome some of…
  • Abstract Number: 1053 • ACR Convergence 2022

    The Collaborative National Quality and Efficacy Registry for Scleroderma: Association of Resource Utilization and Gastrointestinal Tract Symptoms in Early Disease

    Sarah Luebker1, Tracy Frech1, Shervin Assassi2, Jessica Gordon3, Elana Bernstein4, Virginia Steen5, Laura Hummers6, Ami Shah7, Carrie Richardson8, Dinesh Khanna9, Flavia Castelino10, Lorinda Chung11, Faye Hant12, Vicki Shanmugam13, John VanBuren14, Jessica Alvey14, Monica Harding14, Luke Evnin15 and Nora Sandorfi16, 1Vanderbilt University Medical Center, Nashville, TN, 2McGovern Medical School, University of Texas, Houston, TX, 3Hospital for Special Surgery, New York, NY, 4Columbia University, New York, NY, 5Georgetown University School of Medicine, Washington, DC, 6Johns Hopkins Univerisity, Baltimore, MD, 7Johns Hopkins Rheumatology, Baltimore, MD, 8Northwestern University, Chicago, IL, 9Division of Rheumatology, Department of Internal Medicine, Scleroderma Program, University of Michigan, Ann Arbor, MI, 10Massachusetts General Hospital, Boston, MA, 11Stanford University, Stanford, CA, 12Medical University of South Carolina, Charleston, SC, 13George Washington University, Washington, DC, 14University of Utah, Salt Lake City, UT, 15Scleroderma Research Foundation, Brisbane, CA, 16University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Health costs and resource utilization are important in chronic disease management. Systemic sclerosis (SSc) is a multi-organ system disease with outcomes that are often…
  • Abstract Number: 1052 • ACR Convergence 2022

    Short-term Safety of COVID-19 Vaccination in Systemic Sclerosis Patients: Report from a Global Patient-Reported E-survey

    Darpan Thakare1, Naveen R1, John Pauling2, Sakir Ahmed3, Chris Wincup4, Nicolletta Del Papa5, Gianluca Sambataro6, Fabiola Atzeni7, Marcello Govoni8, SIMONE PARISI9, Elena Bartoloni Bocci10, Gian Domenico Sebastiani11, Enrico Fusaro12, Marco Sebastiani13, Luca Quartuccio14, Franco Franceschini15, Pier Paolo Sainaghi16, Giovanni Orsolini17, Rossella De Angelis18, Maria Giovanna Danielli19, Vincenzo Venerito20, Parikshit Sen21, Minchul Kim22, Abraham Edgar Gracia-Ramos23, Akira Yoshida24, James B. Lilleker25, Vishwesh Agarwal26, Sinan Kardes27, Jessica Day28, Marcin Milchert29, Mrudula Joshi30, Tamer A Gheita31, Babur Salim32, Ioannis Parodis33, Albert Selva O’Callaghan34, Elena Nikiphorou35, Tulika Chatterjee22, Ai Lyn Tan36, Arvind Nune37, Lorenzo Cavagna38, Samuel Shinjo39, Nelly Ziade40, Johannes Knitza41, Hector Chinoy42, Oliver Distler43, Masataka Kuwana44, Rohit Aggarwal45, Latika Gupta46, Vikas Agarwal1 and Ashima Makol47, 1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 2North Bristol NHS Trust, Bristol, United Kingdom, 3Kalinga Institute of Medical Sciences, Bhubaneswar, India, 4Rayne Institute, University College London, London, United Kingdom, 5Unità operativa complessa (UOC) Day Hospital Reumatologia via Gaetano Pini 9, Centro Specialistico Ortopedico Traumatologico, Gaetano Pini-CTO,, Milano, 6Medico Immunologia e reumatologia presso, Artoreuma S.R.L., Cors S, Mascalucia, 7Rheumatology Unit, University of Messina, Messina, Italy, 8S. Anna Hospital and University of Ferrara, Ferrara, Italy, 9Italian Society for Rheumatology, Turin, Italy, 10Rheumatology Unit. Department of Medicine, Perugia, Perugia, Italy, 11U.O.C. Reumatologia, Ospedale San Camillo-Forlanini,, Roma, 12Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Turin, Italy, 13Azienda Policlinico di Modena, Modena, Italy, 14Department of Medicine (DAME), ASUFC, University of Udine, Udine, 15Department of Clinical and Experimental Sciences, ASST Spedali Civili and University of Brescia, Brescia, Italy, 16IRCAD, Interdisciplinary Research Center of Autoimmune Diseases, Novara, Italy, 17Department of Medicine, Rheumatology Unit, University of Verona, Verona, Verona, 18Rheumatology Unit, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Marche, Italy, 19Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle, Marche, Italy, 20Department of Emergency and Organ Transplantations-Rheumatology Unit, University of Bari "Aldo Moro", Bari, Italy, 21Maulana Azad Medical College, New Delhi, India, 22University of Illinois College of Medicine Peoria, Peoria, IL, 23Instituto Mexicano del Seguro Social, Ciudad de México, Mexico, 24Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan, 25The University of Manchester, Manchester, United Kingdom, 26Mahatma Gandhi Missions Medical College, Lucknow, India, 27Istanbul University, Istanbul, Turkey, 28Walter and Eliza Hall Institute, Melbourne, Australia, 29Pomeranian Medical University in Szczecin, Szczecin, Poland, 30Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 31Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, 32Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, 33Karolinska Institutet, Stockholm, Sweden, 34Hospital Universitari Vall d'Hebron, Barcelona, Spain, 35Leiden University Medical Center & King's College London, London, United Kingdom, 36University of Leeds, Leeds, United Kingdom, 37Southport and Ormskirk Hospital NHS Trust, Southport, United Kingdom, 38Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Pavia, Italy, 39Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil, 40Saint-Joseph University, Beirut, Lebanon, 41Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 42The University of Manchester, Sale, United Kingdom, 43Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 44Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 45Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 46Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 47Mayo Clinic, Rochester, MN, Rochester, MN

    Background/Purpose: Dedicated data on COVID-19 vaccine-related adverse events (ADEs) in patients with systemic sclerosis (SSc) is limited. Therefore, we aimed to compare all patient-reported ADEs…
  • Abstract Number: 1064 • ACR Convergence 2022

    Test-retest Reliability for the Mawdsley Calcinosis Questionnaire for the Measurement of Calcinosis Burden in Patients with Systemic Sclerosis

    Antonia Valenzuela1, Anne-Marie Russell2, Lorinda Chung3, Kelly Jensen4 and Lesley Ann Saketkoo5, 1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2University of Exeter, Exeter, United Kingdom, 3Stanford University, Stanford, CA, 4University of Colorado, Bellevue, WA, 5University Medical Center - Comprehensive Pulmonary Hypertension Center and ILD Clinic Programs // New Orleans Scleroderma and Sarcoidosis Patient Care & Research Centeris, New Orleans, LA

    Background/Purpose: Calcinosis cutis is a debilitating manifestation in systemic sclerosis (SSc) responsible for a high burden of disability and hand dysfunction, contributing as much as…
  • Abstract Number: 1065 • ACR Convergence 2022

    Biosamples from VEDOSS Patients Show Pathological Signs of SSc: Opportunity for a Biololgical Diagnosis of Disease

    Rebecca Ross1, Emily Clarke1, Will Merchant1, Panji Mulipa1, Natalia Riobo-DelGaldo1 and Francesco Del Galdo2, 1University of Leeds, Leeds, United Kingdom, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, Faculty of Medicine and Health and NIHR Biomedical Research Centre, University of Leeds, Leeds, United Kingdom

    Background/Purpose: The VEDOSS study has recently indicated that more than 50% of patients affected by Raynaud’s phenomenon (RP) and specific SSc anti-nuclear antibodies (ANA) and/or…
  • Abstract Number: 1055 • ACR Convergence 2022

    Associations of Potential Risk Factors with Severe Outcomes in Scleroderma Renal Crisis: Results from a Single Center Study

    Alex Luta1, Saloni Godbole1 and Virginia Steen2, 1Medstar Georgetown University Hospital, Washington, DC, 2Georgetown University School of Medicine, Washington, DC

    Background/Purpose: Scleroderma Renal Crisis (SRC) is a severe and life-threatening complication of Systemic Sclerosis (SSc). Given the rare nature of SSc, it is challenging to…
  • Abstract Number: 1063 • ACR Convergence 2022

    Assessment of Calcinosis in Portuguese Patients with Systemic Sclerosis – a Multicenter Study

    Beatriz Samões1, Diogo Fonseca1, Tiago Beirão1, Flavio Costa1, Romana Vieira1, Georgina Terroso2, Raquel Ferreira2, Rafaela teixeira3, André Saraiva4, Maria João Henriques5, Ana Catarina Duarte6, Ana Cristina Cordeiro6, Paulo Vilas-Boas7, Inês Genrinho3, Ana Bento da Silva8, Laura Gago8, Catarina Resende9, Patricia Martins9, Nathalie Madeira10, Sara Paiva Dinis10, Maura Couto3, Inês Santos3, Filipe Araújo11, Ana Filipa Mourão11, Miguel Guerra12, Margarida Oliveira12, Alexandra Daniel13, Marília Rodrigues13, Catarina Soares14, Hugo Parente15, Carolina Furtado16, Tomás Fontes16 and Joana Abelha-Aleixo1, 1Rheumatology Department, Centro Hospitalar de Vila Nova de Gaia / Espinho, Vila Nova de Gaia, Portugal, 2Rheumatology department, Centro Hospitalar Universitário de São João, Porto, Portugal, 3Rheumatology department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal, 4Rheumatology department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 5Rheumatology department, Centro Hospitalar e Universitário de Coimbra, Lisboa, Portugal, 6Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, 7Rheumatology Department, Centro Hospitalar Baixo Vouga, Aveiro, Portugal, 8Rheumatology department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal, 9Rheumatology department, Centro Hospitalar e Universitário de Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisboa, Portugal, 10Rheumatology department, Unidade Local de Saúde da Guarda - Hospital Sousa Martins, Guarda, Portugal, 11Rheumatology and Osteoporosis Unit, Hospital de Sant´Ana, SCML, Lisboa, Portugal, 12Rheumatology Department, Centro Hospitalar Universitário da Cova da Beira, Covilhã, Portugal, 13Rheumatology department, Hospital Distrital de Leiria, Leiria, Portugal, 14Rheumatology department, Unidade Local de Saúde do Alto Minho, Ponte de Lima, Viana do Castelo, Portugal, 15Rheumatology department, Unidade Local de Saúde do Alto Minho, Ponte de Lima, Portugal, 16Rheumatology department, Hospital do Divino Espírito Santo, Ponta Delgada, Portugal

    Background/Purpose: Calcinosis is a challenging problem among Systemic Sclerosis (SSc) patients with a reported prevalence of 18-49%. We aim to define the prevalence of clinical…
  • Abstract Number: 1076 • ACR Convergence 2022

    ANCA-Associated Vasculitis Treated with Avacopan versus a Standard Prednisone Taper: Glucocorticoid Toxicity Index Scores by Domain

    Naomi Patel1, David Jayne2, Peter Merkel3, Pirow Bekker4, yuqing zhang5, Huibin Yue4 and John Stone6, 1Massachusetts General Hospital, Sale Creek, TN, 2University of Cambridge, Cambridge, United Kingdom, 3University of Pennsylvania, Philadelphia, PA, 4ChemoCentryx, San Juan Capistrano, CA, 5Massachusetts General Hospital, Quincy, MA, 6Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: The ADVOCATE trial (Jayne DRW et al, N Engl J Med, 2021) was a randomized, double-blind, controlled trial of avacopan vs prednisone in addition…
  • Abstract Number: 1070 • ACR Convergence 2022

    Discordance of Patient, Physician and Nurse Practitioner Assessment of Disease Burden in Systemic Sclerosis

    Maylen Nordgård Carstens1, Håvard Fretheim1, Imon Barua1, Henriette Didriksen2, Torhild Garen1, Øyvind Midtvedt1, Øyvind Molberg3 and Anna-Maria Hoffmann-Vold1, 1Oslo University Hospital, Oslo, Norway, 2Oslo University Hospital, Moss, Norway, 3Department of Rheumatology, Oslo University Hospital, Oslo, Norway, Oslo, Norway

    Background/Purpose: Assessment of disease burden is crucial in the management of systemic sclerosis (SSc). The patient global assessment (PatGA) is a patient self-reported measure widely…
  • Abstract Number: 1072 • ACR Convergence 2022

    Efficacy and Safety Assessment of a Rituximab Biosimilar in Patients with Granulomatosis with Polyangiitis (GPA)

    Adil Vural1, Komal Mushtaq1, Chao Zhang1, Mahmoud Alwakeel1, Vickie Sayles1, Kristine Duly2, Carol Langford1 and Rula Hajj-Ali3, 1Cleveland Clinic, Cleveland, OH, 2Cleveland Clinic, Fairview Park, OH, 3Cleveland Clinic, Hunting Valley, OH

    Background/Purpose: A biosimilar is a medication that is highly similar to a biologic agent that is already approved by a regulatory organization. Considering the share…
  • Abstract Number: 1068 • ACR Convergence 2022

    Anti-vinculin Antibodies in Systemic Sclerosis: Associations with Slow Gastric Transit and Extra-Intestinal Clinical Phenotype

    Maria Herran1, Brit Adler2, Jamie Perin3, Walter Morales4, Mark Pimentel5 and Zsuzsanna McMahan6, 1School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia, 2Johns Hopkins University, Division of Rheumatology, Baltimore, MD, 3John Hopkins University, Baltimore, MD, 4Medically Associated Science and Technology (MAST) Program, Cedars-Sinai, Los Angeles, CA, 5Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai, Los Angeles, CA, 6Johns Hopkins Rheumatology, Baltimore, MD

    Background/Purpose: The gastrointestinal tract is commonly affected in systemic sclerosis (SSc). Prior studies have reported an association between higher levels of anti-vinculin antibodies and gastrointestinal…
  • Abstract Number: 1022 • ACR Convergence 2022

    Validation of the SPARCCRETIC E-Tool for Ensuring Scoring Proficiency of MRI Lesions in Axial Spondyloarthritis

    Walter P Maksymowych1, Anna Hadsbjerg2, Mikkel Østergaard3, Raphael Micheroli4, Susanne J. Pedersen5, Adrian Ciurea6, Nora Vladimirova2, Michael Nissen7, Kristyna Bubova8, Stephanie Wichuk9, Manouk de Hooge10, Ashish J Mathew11, Karlo Pintaric12, Monika gregova13, Ziga Snoj12, Marie Wetterslev14, Karel Gorican15, Joel Paschke16, Iris Eshed17 and Robert G Lambert9, 1Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 3Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 4University Hospital Zurich, Department of Rheumatology, Zürich, Switzerland, 5Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, 6University Hospital Zurich, Zürich, Switzerland, 7Hopitaux Universitaires de Genève, Geneva, Switzerland, 8First Faculty of Medicine, Charles University,, Prague, Czech Republic, 9University of Alberta, Edmonton, AB, Canada, 10Ghent University Hospital, Luxembourg, Luxembourg, 11Rigshospitalet, Copenhagen, Denmark, 12Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 13Institue of Rheumatology, Prague, 14Rigshospitalet, Copenhagen, Glostrup, Denmark, 15MSK radiology unit, Radiology section – Diagnostic department, Geneva University Hospitals, Geneva, Switzerland, 16CARE Arthritis LTD, Edmonton, AB, Canada, 17Sheba Medical Center, Tel Aviv, Israel

    Background/Purpose: Quantification of inflammatory and structural lesions in the sacroiliac joints (SIJ) on MRI scans from patients with axial spondyloarthritis (axSpA) has a growing list…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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