Abstracts Archive - Page 303 of 2425 - ACR Meeting Abstracts

Abstract Number: 2095 • ACR Convergence 2023
Integrated Analysis of Gene Expression and Methylation Identifies Biomarkers Associated with Mode of Action of Upadacitinib Treatment in Rheumatoid Arthritis
Preeti Lal¹, Yilin Xu¹, Thierry Sornasse¹, Rhiya Sharma¹, Laleh Jafarpour¹, Heidi Camp¹ and Iain McInnes², ¹AbbVie, Inc., North Chicago, IL, ²University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Upadacitinib (UPA), an oral Janus kinase (JAK) inhibitor, significantly improves the signs and symptoms of RA patients1-3. The present study aims to elucidate the…
Abstract Number: 2007 • ACR Convergence 2023
Effects of IL-17 Blockade on Skeletal Microarchitecture in Patients with Axial Spondyloarthritis: An HR-pQCT Study
Insa Mannstadt, Donald McMahon, Douglas Mintz, Weija Yuan, Linda Russell, Susan Goodman, Emily Stein and Dalit Ashany, Hospital for Special Surgery, New York, NY
Background/Purpose: Axial spondyloarthritis (AxSpA), a chronic inflammatory rheumatic disease causes abnormal bone growth at the spine and paradoxically has been linked to osteoporosis and fragility…
Abstract Number: 2073 • ACR Convergence 2023
Outcomes of the First Year of a Rheumatology Curriculum at Two Internal Medicine Residency Programs
Laura Arneson¹, Biana Modilevsky² and Anisha Dua¹, ¹Northwestern University, Chicago, IL, ²University of Arizona - Tucson / Banner University Medical Center, Tucson, AZ
Background/Purpose: Enhancing rheumatology education in Internal Medicine (IM) residency may encourage residents to pursue rheumatology careers, and promote familiarity with rheumatology among those entering other…
Abstract Number: 1880 • ACR Convergence 2023
Performance of Machine Learning Algorithms in Discriminating Spondyloarthritis Features on Magnetic Resonance Imaging: A Systematic Review and Meta-analysis
Sun Jae Moon¹, Seulkee Lee¹, Seonyoung Kang¹, Hyungjin Kim¹, Jaejoon Lee¹, Jinseok kim², Eun-Mi Koh³, Jinseub Hwang⁴ and Hoon-Suk Cha¹, ¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, South Korea, ³Health Insurance Review and Assessment Service, Seoul, South Korea, ⁴Department of Data Science, Daegu University, Gyeongsan, South Korea
Background/Purpose: The diagnostic role of Magnetic Resonance Imaging (MRI) for axial spondyloarthritis(axSpA) has grown since introducing the ASAS criteria for axSpA. Recent advances in machine…
Abstract Number: 2004 • ACR Convergence 2023
Bone Health Following Bariatric Surgery: A Single Center Quality Improvement Study
Andrew Benck, Haley Zimmerman, Amy Trang, Najia Shakoor and Sonali Khandelwal, Rush University, Chicago, IL
Background/Purpose: Osteoporosis related fractures cause significant morbidity and mortality. Bariatric weight loss surgery is an independent risk factor for osteoporosis. Post-surgery dual energy X-Ray absorptiometry…
Abstract Number: 2082 • ACR Convergence 2023
Delivery of Rheumatology Education to Internal Medicine Residents in Rwanda: Evaluation of a New Virtual Rheumatology Course Supplemented by On-site Clinical Teaching
Carol Hitchon¹, Becky Abdissa Adugna², Richard Akintayo³, Paul Caldron⁴, Ines Colmegna⁵, Ida Dey⁶, Paul McGill⁷, Andres Ponce⁸, Rosie Scuccimarri⁹, Mohammed Tikly¹⁰, Girish Mody¹¹ and Michele Meltzer¹², ¹University of Manitoba, Winnipeg, MB, Canada, ²Addis Ababa University, Addis Ababa, Ethiopia, ³Dumfries and Galloway Royal Infirmary, Edinburgh, United Kingdom, ⁴Arizona Arthritis & Rheumatology Associates, P.C. - Emeritus (no longer in patient care role), Depoe Bay, OR, ⁵The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, ⁶University of Ghana Medical School, Accra, Ghana, ⁷Department of Rheumatology Stobhill Hospital, Glasgow, United Kingdom, ⁸Jefferson, Philadelphia, PA, ⁹McGill University/Montreal Children's Hospital, Montréal, QC, Canada, ¹⁰Wits University, Johannesburg, South Africa, ¹¹University of KwaZulu-Natal, Durban, South Africa, ¹²Thomas Jefferson University/Rheumatology for All,Inc., Philadelphia, PA
Background/Purpose: There exists a critical lack of rheumatology resources in many parts of the world including sub-Saharan African countries. As a result, in these countries,…
Abstract Number: 2013 • ACR Convergence 2023
Clinical Characteristics and Risk Factors Associated with Fragility Fractures in Patients with Primary and Idiopathic Mast Cell Activation Syndromes
Ana Isabel Ramos Lisbona¹, Karen Carpio Astudillo¹, Filip Skrabski¹, Alicia Prieto García¹, Isabel Castrejon¹, Javier Rivera², José María Álvaro-Gracia¹ and Teresa González¹, ¹Hospital General Universitario Gregorio Marañón, Madrid, Spain, ²Hospital General Universitario Gregorio Marañon, Madrid, Spain
Background/Purpose: Mast Cell Activation Syndromes (MCAS) are a group of disorders presenting with episodic multisystem symptoms, predominantly anaphylaxis, as the result of mast cell mediator…
Abstract Number: 1886 • ACR Convergence 2023
Costotransverse Joint Ankylosis and Association with Syndesmophyte Progression in Patients with Radiographic Axial Spondyloarthritis
Hong Ki Min¹, Se Hee Kim², Hae-Rim Kim³, Sang-Heon Lee¹ and Sang-Hoon Lee², ¹Konkuk University School of Medicine, Seoul, South Korea, ²Kyung Hee University Hospital at Gangdong, Seoul, South Korea, ³Rheumatology, Konkuk University Medical Center, Seoul, South Korea
Background/Purpose: Costotransverse joint ankylosis in radiographic axial spondyloarthritis (r-axSpA) patients was measured. Furthermore, the association between syndesmophyte progression assessed by CT syndesmophyte score (CTSS) and…
Abstract Number: 1249 • ACR Convergence 2023
Cross-Sectional Associations of Emotional Distress and Cardiovascular Health in Juvenile Lupus and Dermatomyositis
Kaveh Ardalan¹, Angel Davalos¹, Hwanhee Hong¹, Bryce Reeve¹, Christoph Hornik¹, M. Anthony Moody¹, Donald Lloyd-Jones², Eveline Wu³, Audrey Ward¹, Rebecca Sadun⁴, Jeffrey Dvergsten⁵, Ann Reed⁶, Mark Connelly⁷ and Laura Schanberg¹, ¹Duke University School of Medicine, Durham, NC, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³University of North Carolina School of Medicine, Chapel Hill, NC, ⁴Duke University, Durham, NC, ⁵Duke University School of Medicine, Hillsborough, NC, ⁶Duke University School of Medicine, Chapel HIll, NC, ⁷Children's Mercy Kansas City / University of Missouri-Kansas City School of Medicine, Kansas City, MO
Background/Purpose: Juvenile lupus (JSLE) and dermatomyositis (JDM) patients are at high risk for cardiovascular disease (CVD). The American Heart Association cardiovascular health (CVH) construct is…
Abstract Number: 1873 • ACR Convergence 2023
Cervical Spine Involvement in Axial Spondyloarthritis. Radiographic Characteristics and Associated Factors
pol Maymó¹, Laura Berbel Arcobé², Xabi Michelena³, José Antonio Narvaez², Joan Miquel Nolla⁴, Lídia Valencia², Judith Palacios⁴ and Xavier Juanola Roura¹, ¹Hospital Universitari de Bellvitge, Barcelona, Spain, ²H.U. Bellvitge, Barcelona, Spain, ³Vall Hebron University Hospital, Rheumatology Department, Barcelona, Spain, ⁴Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: The study of the cervical spine (CS) in axial spondyloarthritis (axSpA) and its radiographic characteristics including the zygapophyseal joints (ZJ) may be helpful for…
Abstract Number: 1361 • ACR Convergence 2023
Effect of Zen/Doria Remission and Glucocorticoid Dosage on the Pregnancy Outcome of SLE: Retrospective Study in Two Japanese Tertiary Referral Centers
Takehiro Nakai¹, Nanase Honda², Sho Fukui³, Ayako Kitada¹, Naoto Yokogawa⁴ and Masato Okada¹, ¹St. Luke's International Hospital, Tokyo, Japan, ²Tokyo Metropolitan Tama Medical Center, Fuchu-shi, Japan, ³Brigham and Women's Hospital, Boston, MA, ⁴Tokyo Metropolitan Tama Medical Center, Taito City, Tokyo, Japan
Background/Purpose: Achieving remission is one of the treatment targets in the lupus care and it is also important in preventing the prevalence of adverse pregnancy…
Abstract Number: 1287 • ACR Convergence 2023
Impact of Body Mass Index (BMI) on Rheumatoid Arthritis Disease Activity and Musculoskeletal Ultrasound Measures
Nicolette Morris¹, Elena Saab², Lucia Chen¹, Jenny Brook¹, Gurjit S Kaeley³, David Elashoff¹ and Veena Ranganath¹, ¹David Geffen School of Medicine, UCLA, Los Angeles, CA, ²Wake Forest University School of Medicine, Los Angeles, CA, ³University of Florida College of Medicine – Jacksonville, Ponte Vedra Beach, FL
Background/Purpose: Rheumatoid arthritis (RA) patients with obesity are less likely to respond to therapy and achieve remission. Obesity is a known driver of inflammatory processes…
Abstract Number: 1371 • ACR Convergence 2023
Are Ultrasound Salivary Parenchymal Abnormalities More Severe in Primary Sjögren Patients with a Higher Disease Duration ? A Cross-sectional International Study
Alice TISON¹, sandrine jousse joulin², Maëlys Consigny³, Philipp Moog⁴, Benedikt Hofauer⁵, Eric Hachulla⁶, Christophe Lamotte⁷, JACQUES MOREL⁸, Gael Mouterde⁹, Vera Milic¹⁰, Hendrika Bootsma¹¹, Alja Stel¹², Benjamin A Fisher¹³, Mark Maybury¹⁴, Alan Baer¹⁵, Dana Direnzo¹⁶, Hae-Rim Kim¹⁷, Hong Ki Min¹⁸, Shin-Seok Lee¹⁹, Sung-Eun Choi¹⁹, Guillermo CARVAJAL ALEGRIA²⁰, Sylvie Boisramé²¹, Dewi Guellec²², Divi Cornec²³, Malin Jonsson²⁴, Daniel Hammenfors²⁵, Alain SARAUX²⁶ and Valerie Devauchelle²⁷, ¹CHU de la Cavale Blanche, Brest, France, ²Rheumatology, CHU Brest, Brest, France, ³Biostatistics, CHU Brest, Brest, France, ⁴Rheumatology, CHU Munich, Munich, Germany, ⁵Otolaryngology, CHU Munich, Munich, Germany, ⁶University of Lille, Lille, France, ⁷Internal Medicine and Clinical Immunology, CHU Lille, Lille, France, ⁸Protocole thérapeutique immuno-rhumatologie, Montpellier, France, ⁹CHU Lapeyronie, Montpellier, France, ¹⁰Rheumatology, University of Belgrade, Medical School, Belgrade, Serbia, ¹¹Department of Rheumatology, University Medical Centre Groningen, Groningen, Netherlands, ¹²Rheumatology and clinical immunology, University Medical Center Groningen, Groningen, Netherlands, ¹³University of Birmingham, Birmingham, United Kingdom, ¹⁴Rheumatology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, ¹⁵Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁶University of Pennsylvania, Bala Cynwyd, PA, ¹⁷Rheumatology, Konkuk University Medical Center, Seoul, South Korea, ¹⁸Konkuk University School of Medicine, Seoul, South Korea, ¹⁹Chonnam National University Medical School & Hospital, Gwangju, South Korea, ²⁰CHRU de Tours, Tours, France, ²¹Ondontology, CHU Brest, France, Brest, France, ²²CHU de Brest, Brest, France, ²³University of Brest, Brest, France, ²⁴Clinical dentistry, University of Bergen, Bergen, Norway, Bergen, Norway, ²⁵Rheumatology, Haukeland University Hospital, Bergen, Norway, ²⁶CHU Brest, Brest, France, ²⁷UBO, Brest, France
Background/Purpose: Salivary gland ultrasonography (SGUS) is commonly used in primary Sjögren Disease (pSD) as a diagnostic tool. It could also be used to monitor disease…
Abstract Number: 1882 • ACR Convergence 2023
Imaging in Diagnosis, Monitoring and Outcome Prediction of Large Vessel Vasculitis: A Systematic Literature Review Informing the 2023 Update of the EULAR Recommendations
Philipp Bosch¹, Milena Bond², Christian Dejaco³, Cristina Ponte⁴, Sarah Mackie⁵, Louise Falzon⁶, Wolfgang Schmidt⁷ and Sofia Ramiro⁸, ¹Medical University of Graz, Graz, Austria, ²Azienda sanitaria dell'Alto Adige, Merano, Italy, ³Department of Rheumatology, Medical University Graz, Graz, Austria; Department of Rheumatology, Hospital of Bruneck (ASAA-SABES), Teaching Hospital of the Paracelsius Medical University, Brunico, Italy, ⁴Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁶University of Sheffield, Sheffield, United Kingdom, ⁷Immanuel Krankenhaus Berlin, Berlin, Germany, ⁸Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Since the development of the EULAR recommendations for the use of imaging in large vessel vasculitis (LVV) in 2017, new data has emerged in…
Abstract Number: 1893 • ACR Convergence 2023
Abnormalities Detected with [18F]-FDG-PET/CT Imaging in VEXAS Syndrome
Albrecht Betrains¹, Vincent Jachiet², Yannick Dieudonne³, Jérémie Dion⁴, Estibaliz Lazaro⁵, Claire De Moreuil⁶, Samuel Ardois⁷, Sylvie Grosleron⁸, Jean-benoit Arlet⁹, Cécile-Audrey Durel¹⁰, Laure Delaval¹¹, Sylvain Audia¹², Cécile Golden¹³, Barbara Nicolas¹³, Vincent Langlois¹⁴, Antoinette Perlat⁷, Frédéric Vandergheynst¹⁵, Thomas Moulinet¹⁶, Maxime Samson¹⁷, Daniel Blockmans¹, Olivier Kosmider¹⁸, Sophie Georgin-Lavialle¹⁹, Arsène Mekinian²⁰ and Benjamin Terrier²¹, ¹Department of General Internal Medicine, University Hospitals Leuven, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium, ²Service de médecine interne et Inflammation-Immunopathology-Biotherapy Department (DMU i3), Sorbonne Université, AP-HP, Hôpital Saint Antoine, Paris, France, ³Department of Clinical Immunology and Internal Medicine, National Reference Centre for Systemic Autoimmune Diseases (CNR RESO), Strasbourg University Hospital, Strasbourg, France, ⁴Internal Medicine Department, Toulouse University Hospital, Toulouse, France, ⁵Bordeaux Hospital University, Pessac, France, ⁶CHU de Brest, Brest, France, ⁷CHU Rennes, Rennes, France, ⁸CH Agen-Nérac, Agen, France, ⁹Hôpital Georges-Pompidou APHP, Paris, France, ¹⁰CHU Lyon, Lyon, France, ¹¹Hôpital Bichat APHP, Paris, France, ¹²Department of Internal Medicine and Clinical Immunology, Dijon-Bourgogne University Hospital, Dijon, France, ¹³CHU Dijon, Dijon, France, ¹⁴Service de Médecine Interne, Hôpital Jacques Monod, Le Havre, France, ¹⁵Université Libre de Bruxelles, Bruxelles, Belgium, ¹⁶Department of Internal Medicine, Centre hospitalier universitaire de Nancy, Nancy, France, ¹⁷Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, ¹⁸Hôpital Cochin APHP, Paris, France, ¹⁹AP-HP, Tenon hospital, Paris, France, ²⁰Department of Internal Medicine, Hôpital Saint-Antoine, AP-HP, Paris, France, ²¹Department of Internal Medicine, Hôpital Cochin, AP-HP, Paris, France
Background/Purpose: VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is anautoinflammatory syndrome caused by somatic mosaicism in the UBA1 gene. [18F]-FDG-PET/CT is often performed during…

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