Abstracts Archive - Page 2417 of 2425 - ACR Meeting Abstracts

Abstract Number: 86 • 2012 ACR/ARHP Annual Meeting
Longitudinal Hypertension Diagnosis and Control Among a Primary Care Medically Homed Population with Rheumatoid Arthritis
Katya Voelker¹ and Christie M. Bartels², ¹Univ of Wisconsin School of Medicine and Public Health, Madison, AA, ²Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
Longitudinal Hypertension Diagnosis and Control among a Primary Care Medically Homed Population with Rheumatoid ArthritisBackground/Purpose: Hypertension is a key risk factor for cardiovascular disease (CVD)…
Abstract Number: 46 • 2012 ACR/ARHP Annual Meeting
Synovitis in Secondary Osteoarthritis Due to Rheumatoid Arthritis: A Proof-of-Concept Study
Stefan Vordenbäumen¹, Tim Lögters², Philipp Sewerin¹, Thomas Pauly³, Ellen Bleck⁴, Paulina Philippski¹, Matthias Schneider¹, Michael Schädel-Höpfner² and Benedikt Ostendorf¹, ¹Endocrinology, Diabetology and Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany, ²Trauma and Hand Surgery, Heinrich-Heine-University, Düsseldorf, Germany, ³Orthopaedics, Rheinisches Rheumazentrum St. Elisabeth-Hospital, Meerbusch, Germany, ⁴Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany
Background/Purpose: Rheumatoid arthritis (RA) is characterized by considerable synovial inflammation which may result in secondary osteoarthritis (sOA). Primary OA (pOA) occurs in patients without predisposing…
Abstract Number: 47 • 2012 ACR/ARHP Annual Meeting
Accumulation of CD34+ Hematopoietic Stem Cells in the Initial Inflammatory Human Fracture Hematoma Is Mediated Via Chemokine Receptor Type 3 Ligands
Paula Hoff¹, Timo Gaber¹, Martin Hahne¹, Cindy Strehl¹, Katharina Schmidt-Bleek², Gerd Burmester³, Gerhard Schmidmaier⁴, Georg Duda⁵, Carsten Perka⁶ and Frank Buttgereit⁷, ¹Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ²Julius Wolff Institut, Charité University Medicine, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Department of Traumatology, Heidelberg University Hospital, Heidelberg, Germany, ⁵Julius Wolff Institute, Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁶Center of Muscoloskeletal Surgery, Charité University Medicine, Berlin, Germany, ⁷Charité - Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: We have previously shown the early phase of human fracture healing to be characterized by hypoxia which promotes inflammation and chemoattraction. Hypoxia is also…
Abstract Number: 48 • 2012 ACR/ARHP Annual Meeting
Tissue Engineering for Articular Cartilage Repair, Culturing Bone Marrow Mesenchymal Stem Cells On Collagen and Heparan Sulphate Scaffolds
Adela Helvia Martinez-Sanchez¹, Clara Sanjurjo-Rodriguez¹, Silvia Diaz-Prado², Emma Muiños¹, Isaac M. Fuentes², Francisco J. De Toro², Julia Bujan³ and Francisco J. Blanco¹, ¹Osteoarticular and Aging Res. Lab. CIBER-BBN. Rheumatology Div. INIBIC-Complejo Hosp. Univ. A Coruña, A Coruña, Spain, ²Osteoarticular and Aging Res. Lab. CIBER-BBN. INIBIC-University of A Coruña, A Coruña, Spain, ³Department of Medical Specialties. University of Alcala de Henares, Madrid, Spain
Background/Purpose: The aim of this study was to evaluate the chondrogenic potential of bone marrow mesenchymal stem cells (BM-MSCs) grown on type I collagen and…
Abstract Number: 49 • 2012 ACR/ARHP Annual Meeting
The Spatial Energy Expenditure Configuration and Possible Applications in an Experimental Model of Arthritis
Susanne Klatt¹ and Rainer H. Straub², ¹Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrine Immunology, University Hospital Regensburg, Regensburg, 93055, Germany, ²Department of Internal Medicine 1, University Hospital Regensburg, Regensburg, Germany
Background/Purpose: An autoimmune response with differentiation and proliferation of immune cells and the subsequent tissue-directed inflammatory process in the symptomatic phase of the disease are…
Abstract Number: 50 • 2012 ACR/ARHP Annual Meeting
Human Chondrocyte Dedifferentiation Is Accompagnied by CD105 Endoglin Expression, ALK-1/Smad1/5 Phosphorylation and Leptin Production – Stimulation by Prednisolone and Aldosterone Through the Glucocorticoid Receptor
Olivier Malaise¹, Biserka Relic², Mustapha Zeddou¹, Edith Charlier¹, Florence Quesada Calvo¹, Sophie Neuville³, Dominique de Seny² and Michel G. Malaise⁴, ¹Department of Rheumatology, GIGA Research - University of Liège - CHU Liège, Liège, Belgium, ²Department of Rheumatology, GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ³GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ⁴Department of Rheumatology, University of Liège - CHU Liège, Liège, Belgium
Background/Purpose: Leptin, mainly produced by the adipose tissue including fat neighboring the joint, is considered as pro-inflammatory in osteoarthritis (OA). Normal cartilage does not…
Abstract Number: 51 • 2012 ACR/ARHP Annual Meeting
Phosphodiesterase 4 Expression in Rheumatoid Arthritis Synovium and Anti-Inflammatory Effects of Apremilast On Synovial Fibroblasts
Lei Wu, Mary Adams, Stacey Parton and Peter Schafer, Department of Translational Development, Celgene Corporation, Summit, NJ
Background/Purpose: Apremilast (APR), a small molecule specific inhibitor of phosphodiesterase 4 (PDE4), works intracellularly to modulate pro- and anti-inflammatory mediator production in both immune and…
Abstract Number: 52 • 2012 ACR/ARHP Annual Meeting
The Validity of the Diagnosis Inflammatory Arthritis in Primary Care
Markus M.J. Nielen¹, Jennie Ursum¹, François G. Schellevis² and Joke C. Korevaar¹, ¹NIVEL (Netherlands Institute for Health Services Research), Utrecht, Netherlands, ²Department of General Practice and Elderly Care Medicine/EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, Netherlands
Background/Purpose: Large population-based databases, such as electronic medical records (EMRs) from patients in primary care, are useful data sources to investigate morbidity and health care…
Abstract Number: 53 • 2012 ACR/ARHP Annual Meeting
Comparison of Decision Rules for Identifying Patients with Rheumatoid Arthritis (RA) in Administrative Healthcare Databases
John G. Hanly, Kara Thompson and Chris Skedgel, Division of Rheumatology, Dalhousie University and Capital Health, Halifax, NS, Canada
Background/Purpose: Identification of RA cases in administrative healthcare databases is used to estimate disease frequency, healthcare utilization and cost for RA. However, the optimal methodology…
Abstract Number: 54 • 2012 ACR/ARHP Annual Meeting
Use of Health Plan Data to Assess Feasibility of Large Pragmatic Clinical Trials in Rheumatoid Arthritis
Jeffrey R. Curtis¹, Lang Chen², Fenglong Xie³, Jie Zhang¹, Kenneth G. Saag⁴, Stacey Cofield⁵, Kevin L. Winthrop⁶, Nicole C. Wright⁷ and Elizabeth S. Delzell⁸, ¹Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ⁴Div Clinical Immun & Rheum, Univ of Alabama-Birmingham, Birmingham, AL, ⁵School of Public Health, Department of Biostatistics, Univ of Alabama at Birmingham,, Birmingham, AL, ⁶Dept of Infectious Disease, Oregon Health & Science University, Portland, OR, ⁷Epidemiology, The University of Alabama at Birmingham, Birmingham, AL, ⁸Epidemiology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Large pragmatic clinical trials (PCTs) are increasingly used to conduct comparative effectiveness research (CER). PCTs typically have simple inclusion/exclusion criteria and hard outcomes (e.g.…
Abstract Number: 55 • 2012 ACR/ARHP Annual Meeting
Accuracy of Canadian Health Administrative Databases in Identifying Patients with Rheumatoid Arthritis Seen by Rheumatologists
Jessica Widdifield¹, Sasha Bernatsky², J. Michael Paterson³, Karen Tu³, Ryan Ng³, J. Carter Thorne⁴, Janet E. Pope⁵ and Claire Bombardier⁶, ¹University of Toronto, Toronto, ON, Canada, ²Clinical Epidemiology, Research Institute of the McGill University Health Ctre, Montreal, QC, Canada, ³Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ⁴Southlake Regional Health Centre, Newmarket, ON, Canada, ⁵Medicine/Rheumatology, St. Joseph Health Care London, University of Western Ontario, London, ON, Canada, ⁶Rheumatology, University of Toronto, Toronto, ON, Canada
Background/Purpose: In a predominantly universal single-payer health system, Canadian health administrative data are a valuable tool and increasingly used for research. Few studies have rigorously…
Abstract Number: 56 • 2012 ACR/ARHP Annual Meeting
A Validated Mathematical Model Using Electronic Health Records to Identify Rheumatoid Arthritis Patients for Observational Studies
Aarat M. Patel¹, Ilinca D. Metes², Larry W. Moreland³, Melissa Saul⁴, Stephen R. Wisniewski⁵ and Marc C. Levesque⁶, ¹Rheumatology & Clinical Immun / Pediatric Rheumatology, Univ of Pittsburgh Med Ctr / Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Pittsburgh, Pittsburgh, PA, ³Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁴Biomedical Informatics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, ⁵Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ⁶Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: To develop and validate a search algorithm with a high specificity and sensitivity to identify rheumatoid arthritis (RA) patients in a large health care…
Abstract Number: 57 • 2012 ACR/ARHP Annual Meeting
A British Survey of Time to Presentation and Treatment of Rheumatoid Arthritis in Subjects of Black and Minority Ethnic Origin
Sonia Panchal¹, Ash Samanta¹, Arumugam Moorthy¹, Sawson Hayat², Ira Pande², Adewale O. Adebajo³ and Kuntal Chakravarty⁴, ¹Rheumatology, University Hospitals of Leicester, Leicester, United Kingdom, ²Rheumatology, Nottingham University Hospitals, Nottingham, United Kingdom, ³Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom, ⁴Dept of Rheumatology, University of Bedfordshire Post Graduate Medical School, Romford, United Kingdom
Background/Purpose: National guidelines mandate urgent referral of rheumatoid arthritis (RA) for specialist treatment if more than three months from symptom onset; initial combination therapy with…
Abstract Number: 58 • 2012 ACR/ARHP Annual Meeting
5 Million Patients and Not 0.34% Is Worrisome: Burden of Rheumatoid Arthritis in India Based On a Bone and Joint Decade India Community Oriented Program for Control of Rheumatic Disease
Arvind Chopra¹, R. Ghorpade², S. Sarmukkadam³, VL Joshi¹, AJ. Mathews⁴, L. Gauri⁵, A. Rahim⁶, K. Datta⁷, S. Chaturvedi⁸, B. Thakuria⁹, A. Mahajan¹⁰, R. Singh¹¹, A. Ghosh¹², R. Handa¹³, Manjit Saluja¹⁴, A. Venugopalan¹, V. Kunjeer¹, B. Paul⁶, S. Pal⁷, K. Wangjam¹¹, T. Kumar¹⁵ and K. Mahendranath¹⁶, ¹Rheumatology, Center for Rheumatic Diseases, Pune, India, ²Center for Rheumatic Diseases, Pune, India, ³BJMC, Pune, India, ⁴Government Medical College Hospital, Trivandrum, India, ⁵SP Medical College, Bikaner, India, ⁶Calicut Medical College, Calicut, India, ⁷Advance Rheumatology Clinic, Hyderabad, India, ⁸FRCH, Pune, India, ⁹Guwahati Medical College & Hospital, Guwahati, India, ¹⁰Government Medical College, Jammu, India, ¹¹Regional Institute of Medical Sciences, Imphal, Manipur, India, ¹²Rheumatology, Institute of Post Graduate Medical Education and Research, Kolkata, India, ¹³Department of Rheumatology, AIIMS, New Delhi, India, ¹⁴Clinical care, Center for Rheumatic Diseases, Pune, India, ¹⁵Institute of Post Graduate Medical Education and Research, Kolkata, India, ¹⁶Rheumatology Clinic, Bangalore, India
Background/Purpose : The 1 % prevalence of RA Worldwide is a deep rooted ancient dogma. None of the recent WHO ILAR COPCORD (Community Oriented Program…
Abstract Number: 59 • 2012 ACR/ARHP Annual Meeting
A Staggering Burden of Pain and Rheumatic Disorders in India: A National Bone & Joint Decade India Community Oriented Program for Control of Rheumatic Disease Survey 2006-2011
Arvind Chopra¹, R. Ghorpade¹, S. Sarmukkadam², VL Joshi¹, AJ. Mathews³, L. Gauri⁴, A. Rahim⁵, K. Datta⁶, S. Chaturvedi⁷, B. Thakuria⁸, A. Mahajan⁹, R. Singh¹⁰, A. Ghosh¹¹, R. Handa¹², Manjit Saluja¹³, A. Venugopalan¹⁴, V. Kunjeer¹⁴, B. Paul⁵, S. Pal⁶, K. Wangjam¹⁰, T. Kumar¹⁵, CP Rajendran¹⁶, V. Gajalakshmi¹⁷ and K. Mahendranath¹⁸, ¹Rheumatology, Center for Rheumatic Diseases, Pune, India, ²Biostatistics, B J Medical College, Pune, India, ³Government Medical College Hospital, Trivandrum, India, ⁴SP Medical College, Bikaner, India, ⁵Calicut Medical College, Calicut, India, ⁶Advance Rheumatology Clinic, Hyderabad, India, ⁷FRCH, Pune, India, ⁸Guwahati Medical College & Hospital, Guwahati, India, ⁹Government Medical College, Jammu, India, ¹⁰Regional Institute of Medical Sciences, Imphal, Manipur, India, ¹¹Rheumatology, Institute of Post Graduate Medical Education and Research, Kolkata, India, ¹²Department of Rheumatology, AIIMS, New Delhi, India, ¹³Clinical care, Center for Rheumatic Diseases, Pune, India, ¹⁴Center for Rheumatic Diseases, Pune, India, ¹⁵Institute of Post Graduate Medical Education and Research, Kolkata, India, ¹⁶Madras Medical College, Chennai, India, ¹⁷ERC Unit, Chennai, India, ¹⁸Rheumatology clinic, Bangalore, India
Background/Purpose : The maiden COPCORD (Community Oriented Program for Control of Rheumatic Diseases) population survey in village Bhigwan (Pune) findings proposed a high burden of…

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