Abstracts Archive - Page 2405 of 2425 - ACR Meeting Abstracts

Abstract Number: 266 • 2012 ACR/ARHP Annual Meeting
Knee Joint Stabilization Therapy in Patients with Osteoarthritis of the Knee: A Randomized, Controlled Trial
Jesper Knoop¹, Joost Dekker², Marike van der Leeden³, Martin van der Esch¹, Carina A. Thorstensson⁴, Martijn Gerritsen⁵, Ramon E. Voorneman⁵, Wilfred FH Peter¹, Mariette de Rooij¹, Suzanne Romviel¹, Willem F. Lems⁶, Leo D. Roorda⁷ and Martijn P.M. Steultjens⁸, ¹Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ²VU University Medical Centre, Department of Rehabilitation Medicine, EMGO Institute and Department of Psychiatry, Amsterdam, Netherlands, ³Amsterdam Rehabilitation Research Center, Reade, Amsterdam, Netherlands, ⁴Department of Clinical Neurosciences and Rehabilitation, University of Gothenburg, Institute of Neuroscience and Physiology, Gothenburg, Sweden, ⁵Jan van Breemen Research Institute, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ⁶Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ⁷Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁸Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland
Background/Purpose: Patients with knee osteoarthritis (OA) and instability of the knee joint may not benefit optimally from regular strengthening training. Therefore, we evaluated the effectiveness of a newly…
Abstract Number: 227 • 2012 ACR/ARHP Annual Meeting
Long Term Outcome of Interstitial Lung Disease in Idiopathic Inflammatory Myopathies and Amyopathic Dermatomyositis
Machiko Mizushima¹, Hidehiro Yamada², Yoshioki Yamasaki¹, Masaomi Yamasaki³, Minoru Satoh⁴ and Shoichi Ozaki⁵, ¹Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ²Internal Medicine, St. Marianna University, Kawasaki, Japan, ³Internal Medicine, St Marianna University, Yokohama City Seibu Hospital, Yokohama, Japan, ⁴Medicine, University of Florida, Gainesville, FL, ⁵Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: The aim of this study was to assess the long term clinical course and outcome of interstitial lung disease (ILD) in polymyositis/dermatomyositis (PM/DM) and…
Abstract Number: 228 • 2012 ACR/ARHP Annual Meeting
Simultaneous Initiating of Glucocorticoids and disease-Modifying Antirheumatic Drug Therapy in Polymyositis and Dermatomyositis Patients Results in the Opportunity to Taper Dosage of Glucocorticoids Early
Kavish J. Bhansing¹, Piet LCM Van Riel², Sigrid Pillen³, Baziel G.M. van Engelen⁴ and Madelon C. Vonk⁵, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Neurology, Catharina Wilhemina Hospital, Nijmegen, Netherlands, ⁴Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁵Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Glucocorticoids are the cornerstone of therapy in patients with polymyositis (PM) and dermatomyositis (DM). However, side effects are common. Furthermore, glucocorticoids exhibits an…
Abstract Number: 229 • 2012 ACR/ARHP Annual Meeting
Clinical Differences Between Adult and Juvenile Dermatomyositis Associated with Anti-NXP2 Autoantibodies
Sarah Tansley¹, Zoe Betteridge¹, Harsha Gunawardena², Lucy R. Wedderburn³, Hector Chinoy⁴, Robert G. Cooper⁵, Jiri Vencovsky⁶, Lenka Plestilova⁷, Ingrid E. Lundberg⁸, Katalin Danko⁹, Melinda Vincze¹⁰, Neil McHugh¹¹, UK JDRG¹² and EuMyoNet¹³, ¹Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ²Rheumatology, North Bristol NHS Trust, Bristol, United Kingdom, ³Rheumatology Unit , Institute of Child Health, University College London (UCL), London, United Kingdom, ⁴Rheumatology, The University of Manchester, Manchester, United Kingdom, ⁵Rheumatic Diseaes Center, Salford Royal Foundation Trust, Salford, United Kingdom, ⁶Institute of Rheumatology, Prague, Czech Republic, ⁷Institute of Rheumatology, Prague 2, Czech Republic, ⁸Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, ⁹University of Debrecen, University of Debrecen, Debrecan, Hungary, ¹⁰University of Debrecen, University of Debrecen, Debrecen, Hungary, Debrecan, Hungary, ¹¹Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ¹²Institute of Child Health, London, United Kingdom, ¹³Rheumatology Unit, Stockholm, Sweden
Background/Purpose: Myositis specific antibodies (MSA) can divide dermatomyositis patients into distinct clinical subsets and help predict the risk of disease complications such as interstitial lung…
Abstract Number: 230 • 2012 ACR/ARHP Annual Meeting
Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCoR) Antibody in Necrotizing Myopathy and the Role of Statins
Ashima Malik¹, Rohit Aggarwal², Zengbiao Qi³, Noreen Fertig⁴, Diane Koontz⁵, Rufus W. Burlingame⁶, David Lacomis⁷ and Chester V. Oddis⁸, ¹Rheumatology, University of Pittsburgh, Pittsburgh, PA, ²Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, ³Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Department of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁶Rheumatology Research, INOVA Diagnostics, Inc., San Diego, CA, ⁷Neurology, University of Pittsburgh Medical Ctr, Pittsburgh, PA, ⁸Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Statin use is associated with myalgias, muscle weakness and elevated muscle enzymes, but recent reports of a statin-induced immune-mediated necrotizing myopathy (IMNM) have been…
Abstract Number: 231 • 2012 ACR/ARHP Annual Meeting
Pulmonary Hypertension in the Antisynthetase Syndrome
Helena Andersson¹, T. Mogens Aalokken², Torhild Garen³, Oyvind Molberg⁴ and Jan Tore Gran¹, ¹Rheumatology, Oslo University Hospital, Oslo, Norway, ²Department of Radiology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ³Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ⁴Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Background/Purpose: Methods: Objectives: To describe the frequency and clinical characteristics of pulmonary hypertension (PH) in a cohort of Antisynthetase Syndrome (ASS) patients.Methods: Patients from a…
Abstract Number: 232 • 2012 ACR/ARHP Annual Meeting
The Natural History of Sporadic Inclusion Body Myositis – an Observational Longitudinal Study
Pedro Machado¹, Andrea Cortese¹, Jasper Morrow¹, Liz Dewar¹, Andy Hiscock¹, Adrian Miller¹, Stefen Brady², David Hilton-Jones², Matt Parton¹ and Michael G. Hanna¹, ¹MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, United Kingdom, ²Oxford Muscle and Nerve Centre, John Radcliffe Hospital, Oxford, United Kingdom
Background/Purpose: Our aim was to assess prospectively the clinical features and functional impact of inclusion body myositis (IBM), to identify reliable outcome measures for future…
Abstract Number: 233 • 2012 ACR/ARHP Annual Meeting
IFN Signature Is Associated with Autoantibody Profiles in Patients with Idiopathic Inflammatory Myopathies
Saskia Vosslamber¹, Louise Ekholm², Anna Tjarnlund³, Clio P. Mavragani⁴, Lenka Plestilova⁵, Martin Klein⁶, Mary K. Crow⁷, Peter J. Charles⁸, Leonid Padyukov⁹, Jiri Vencovsky⁵, Ingrid E. Lundberg¹⁰ and Cornelis L. Verweij¹, ¹Pathology, VU University Medical Center, Amsterdam, Netherlands, ²Rheumatology Unit, Department of Medicine, Karolinska University Hospital in Solna, Karolinska Institutet, Stockholm, Sweden, ³Pathology, Rheumatology Unit, Department of Medicine, Karolinska University Hospital in Solna, Karolinska Institutet, Stockholm, Sweden, ⁴Department of Experimental Physiology, School of Medicine, University of Athens, Athens, Greece, Athens, Greece, ⁵Institute of Rheumatology, Prague, Czech Republic, ⁶Institute of Rheumatology, Prague, Prague, Czech Republic, ⁷Department of Medicine, Hospital for Special Surgery, New York, NY, ⁸Oxford University, Kennedy Institute of Rheumatology, Oxford, United Kingdom, ⁹Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, ¹⁰Rheumatology Unit, Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Sweden, Stockholm, Sweden
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are rare autoimmune diseases characterized by the presence of autoantibodies, proximal muscle weakness and muscle inflammation. Recent studies showed an…
Abstract Number: 234 • 2012 ACR/ARHP Annual Meeting
Central Sensitization Is Associated with Spontaneous Pain in Knee Osteoarthritis
Anisha B. Dua¹, Tuhina Neogi², Rachel A. Mikolaitis³, Joel A. Block³ and Najia Shakoor⁴, ¹Rheumatology, West Penn Allegheny Health System, Pittsburgh, PA, ²Boston University School of Medicine, Boston, MA, ³Section of Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is a chronic, prevalent disease that is a major cause of pain and disability. Pain is the primary symptom of OA, however…
Abstract Number: 235 • 2012 ACR/ARHP Annual Meeting
Peripheral and Central Sensitization in Patients with Different Degree of Knee Osteoarthritis
Lars Arendt-Nielsen¹, Thomas Navndrup Eskehave², Morten Asser Karsdal³, Anne C. Bay-Jensen⁴, Hans Christian Hoeck² and Ole Simonsen⁵, ¹Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark, ²Center for Clinical and Basic Research and C4Pain, Aalborg, Denmark, ³Nordic Bioscience A/S, Herlev, Denmark, ⁴Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ⁵Frederikshavn Hospital, Frederikshavn, Denmark
Background/Purpose: Though pain is the cardinal symptom of osteoarthritis (OA) the underlying causes are not fully understood. However, peripheral and central sensitization has been suggested…
Abstract Number: 236 • 2012 ACR/ARHP Annual Meeting
The Relationship Between Vibratory Sense and Somatosensory Pain Measures in Knee Osteoarthritis
Anisha B. Dua¹, Rachel A. Mikolaitis², Tuhina Neogi³, Joel A. Block² and Najia Shakoor⁴, ¹Rheumatology, West Penn Allegheny Health System, Pittsburgh, PA, ²Section of Rheumatology, Rush University Medical Center, Chicago, IL, ³Boston University School of Medicine, Boston, MA, ⁴Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Osteoarthritis is the most common form of arthritis, and is a major cause of pain and disability. Continuous nociceptive input can influence somatosensory…
Abstract Number: 237 • 2012 ACR/ARHP Annual Meeting
Association Between Pain Threshold, Symptoms and Radiographic Knee and Hip Osteoarthritis: The Johnston County Osteoarthritis Project
Adam P. Goode¹, Xiaoyan A. Shi², Jordan Renner³, Richard Gracely⁴, Mehrnaz Maleki-Fischbach⁵ and Joanne M. Jordan⁶, ¹Community and Family Medicine, Duke University, Durham, NC, ²SAS Institute, Inc, Cary, NC, ³UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁴Dentistry, University of North Carolina, Chapel Hill, NC, ⁵Medicine, National Jewish Health, Denver, CO, ⁶Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Little is known of the association between pain threshold and knee/hip symptoms as well as radiographic knee/hip osteoarthritis (rOA). These analyses: 1) determined the…
Abstract Number: 238 • 2012 ACR/ARHP Annual Meeting
Inevitable Deterioration? Trajectories and Risk Profiles of Pain in Patients with Radiographic, Symptomatic Knee Osteoarthritis
Jamie E. Collins¹, William M. Reichmann², Jeffrey N. Katz³ and Elena Losina¹, ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Orthopedics, Brigham and Womens Hospital, Boston, MA, ³Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Knee pain is the primary reason that patients with OA seek medical care. The goal of this study is to describe pain trajectory over…
Abstract Number: 239 • 2012 ACR/ARHP Annual Meeting
Knee Osteoarthritis Symptom Assessments That Combine Pain and Physical Activity Are Superior to Pain Alone
Grace H. Lo¹, Timothy E. McAlindon², Gillian A. Hawker³, Jeffrey B. Driban⁴, Lori Lyn Price⁵, Jing Song⁶, Charles Eaton⁷, Marc C. Hochberg⁸, Rebecca D. Jackson⁹, C. Kent Kwoh¹⁰, Michael C. Nevitt¹¹ and Dorothy D. Dunlop⁶, ¹Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, ²Division of Rheumatology, Tufts Medical Center, Boston, MA, ³Women's College Research Institute, University of Toronto, Toronto, ON, Canada, ⁴Rheumatology, Tufts Medical Center, Boston, MA, ⁵Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁶Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁸Department of Medicine, University of Maryland, Baltimore, MD, ⁹Ohio State University, Columbus, OH, ¹⁰School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ¹¹Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA
Background/Purpose : Symptom assessment in knee osteoarthritis (OA) is challenging. Knee pain does not always correlate well with radiographic severity, perhaps because people modify /…
Abstract Number: 240 • 2012 ACR/ARHP Annual Meeting
Degenerative Changes in Patients with Knee Pain: A Comparative Study Between Ultrasound and Conventional Radiology
Santiago Ruta¹, Erika Catay², Javier Rosa², David A. Navarta³, Ricardo Garcia-Monaco⁴ and Enrique R. Soriano⁵, ¹Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: Knee osteoarthritis (OA) is one of the most common rheumatologic joint diseases and causes an important disability in the elderly population. To date the…

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