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  • Abstract Number: 2032 • 2013 ACR/ARHP Annual Meeting

    How Does Age At Onset Influence Autoimmune Rheumatic Diseases?

    Jenny Amaya-Amaya1, Juan-Camilo Sarmiento-Monroy2, Nicolás Molano-González1, Mónica Rodríguez-Jiménez1, Rubén-Darío Mantilla2, Adriana Rojas-Villarraga1 and Juan-Manuel Anaya2, 1Center for Autoimmune Diseases Research (CREA), Universidad del Rosario., Bogota, Colombia, 2School of Medicine and Health Sciences, Universidad del Rosario. Center for Autoimmune Diseases Research (CREA), Bogotá, Colombia

    Background/Purpose: Age at onset of disease (AOD) refers to the time period at which a patient experiences the first sign (s) and symptom(s). AOD varies…
  • Abstract Number: 2033 • 2013 ACR/ARHP Annual Meeting

    Mortality Prognostic Factors Of Patients With Systemic Autoimmune Diseases Admitted To An Intensive Care Unit

    Pamela Inés Doti1, Sara Fernandez2, Emmanuel Coloma3, Ona Escoda3, Ignasi Rodiguez-Pintó3, Pedro Castro2, Gerard Espinosa3 and José María Nicolás2, 1Department of Autoimmune Diseases, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, 2Medical Intensive Care Unit, Hospital Clínic, Barcelona, Barcelona, Spain, 3Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain

    Background/Purpose: To identify mortality prognostic factors of patients with systemic autoimmune diseases (SAD) admitted in a medical intensive care unit (ICU). Methods: Retrospective observational study…
  • Abstract Number: 2034 • 2013 ACR/ARHP Annual Meeting

    Does Mixed Connective Tissue Disease Or Sharp’s Syndrome Really Exist?

    Anne Barbarini1, Christelle Sordet1, Emmanuel Chatelus1, Rose-Marie Javier1, Joelle Goetz2, Francois Lefebvre3, Jacques-Eric Gottenberg4, Thierry Martin5 and Jean Sibilia4, 1Rheumatology, Strasbourg University Hospital, Strasbourg, France, 2rheumatology, Strasbourg University Hospital, Strasbourg, France, 3Strasbourg University Hospital, strasbourg, France, 4Division of Rheumatology, University Hospital of Strasbourg, Strasbourg, France, 5Strasbourg University Hospital, Strasbourg, France

    Background/Purpose: The existence of Mixed Connective Tissue Disease (MCTD) has often been discussed in literature and its diagnostic criteria are very heterogeneous. Anti-U1-RNP antibodies are…
  • Abstract Number: 2035 • 2013 ACR/ARHP Annual Meeting

    Description Of 142 Cases Of Relapsing Polychondritis Followed In a Single Center Since 2000

    Jeremie Dion1,2, Nathalie Costedoat-Chalumeau3, Damien Sene4, Judith Cohen-Bittan5, Gaëlle Leroux6, Camille Francès7 and Jean-Charles Piette8, 1Faculté paris 7 Denis-Diderot, Paris, France, 2Internal medecine, Hopital Cochin, Paris, France, 3Internal Medicine, Hopital Cochin, Paris, France, 4Internal Medicine, Hopital Lariboisière, Paris, France, 5Service de medecine gériatrique, CHU Pitié-Salpêtrière, Paris, France, 6Department of Internal Medicine 1, CHU Pitié-Salpêtrière, Paris, France, 7Service de Dermatologie, Hopital Tenon, Paris, France, 8Department of Internal Medicine 1., CHU Pitié-Salpêtrière, Paris, France

    Background/Purpose: Relapsing polychondritis (RP) is a rare condition characterized by recurrent inflammation of cartilaginous tissues and systemic manifestations. Data on prognosis available from the latest…
  • Abstract Number: 2036 • 2013 ACR/ARHP Annual Meeting

    Biologic Therapy For Relapsing Polychondritis: Old and New Efficacy Indices

    Mattia Baldini1, Patrizia Aiello1, Mirta Tiraboschi1, Maria Grazia Sabbadini2 and Elena Baldissera1, 1Internal Medicine and Clinical Immunology, Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milano, Italy, 2Internal Medicine and Clinical Immunology, Vita-Salute San Raffaele University, Milano, Italy

    Background/Purpose: The inflammatory milieu in affected tissues from Relapsing Polychondritis (RP) is rich in TNF-α, IL-1-β and IL-6. Cytokine-targeted biologic therapies has therefore been proposed…
  • Abstract Number: 2037 • 2013 ACR/ARHP Annual Meeting

    Isolated Anti-Ro52 Antibody – Significance and Clinical Association

    Yogesh Singh1, Pravin Patil2, Hilary Longhurst3, Garry Clarke3 and Bhaskar Dasgupta4, 1Rheumatology, Southend university hospital, Westcliff-on-sea, United Kingdom, 2Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom, 3Immunology, Southend University Hospital, Westcliff on sea, United Kingdom, 4Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom

    Isolated anti-Ro52 antibody – significance and clinical association Background/Purpose: Antibodies against Ro-52 (TRIM21)  have been described in patients with a broad spectrum of autoimmune diseases. Anti-Ro52…
  • Abstract Number: 2038 • 2013 ACR/ARHP Annual Meeting

    Congenital Heart Block Related With Maternal Autoimmune Diseases: Descriptive Analysis Of a Series Of 17 Cases

    Pamela Inés Doti1, Ona Escoda2, Sergi Cesar-Diaz3, Narcís Masoller4, Irene Teixidó4, Josep Maria Martinez4, Georgia Sarquella-Brugada5 and Gerard Espinosa2, 1Department of Autoimmune Diseases, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, 2Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, 3Arrhythmia Unit, Cardiology Section, Arrhythmia Unit, Cardiology Section, Hospital Sant Joan de Déu, Barcelona, Barcelona, Spain, 4Maternal Fetal Medicine Department, Hospital Clínic, Bacelona, Barcelona, Spain, 5Arrhythmia Unit, Cardiology Section, Hospital Sant Joan de Déu, Barcelona, Barcelona, Spain

    Background/Purpose: To describe the clinical characteristics of maternal autoimmune-mediated fetal congenital heart block (CHB) in a cohort of pregnant women from an Autoimmune Diseases Pregnancy…
  • Abstract Number: 2039 • 2013 ACR/ARHP Annual Meeting

    Micro and Nanoparticles As Possible Causative-Prognostic Co-Factors Of Mixed Cryoglobulinemia Syndrome

    Erica Artoni1, Gian Luca Sighinolfi1, Daniele Campioli2, Marco Sebastiani3, Dilia Giuggioli3 and Clodoveo Ferri4, 1Life Sciences, University of Modena and Reggio Emilia, Modena, Italy, 2Laboratory of Clinical Chemistry, Azienda Ospedaliera - Policlino di Modena, Modena, Italy, 3Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy, 4Department of Internal Medicine, University of Modena and Reggio Emilia, Modena, Italy

    Background/Purpose:  We previously demonstrated that patients affected by membranoproliferative glomerulonephritis and mixed cryoglobulinemia syndrome (MCs) show the presence of circulating micro and nanoparticles (MPs and…
  • Abstract Number: 2040 • 2013 ACR/ARHP Annual Meeting

    Pilot Study Of Abatacept In Patients With Refractory Autoimmune Chronic Urticaria

    Clifton O. Bingham III1, Marilyn Towns1 and Susan J. Bartlett2, 1Rheumatology, Johns Hopkins University, Baltimore, MD, 2Clinical Epidemiology, McGill University, Montreal, QC, Canada

    Background/Purpose: Associations between chronic urticaria (CU) with autoantibodies and other autoimmune conditions have implicated T cells in CU initiation and/or propagation. Many patients (pts) have…
  • Abstract Number: 2041 • 2013 ACR/ARHP Annual Meeting

    Pregnancy Outcomes In Women Exposed To Golimumab

    Amy G. Lau1, Michael Clark1, Diane D. Harrison1, Anja Geldhof2, Riikka Nissinen2 and Marilyn Sanders1, 1Janssen Research & Development, LLC., Horsham, PA, 2Janssen Biologics Europe, Leiden, Netherlands

    Background/Purpose: Rheumatologic conditions and inflammatory bowel disease can affect women of childbearing potential. Golimumab (GLM) is approved for rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing…
  • Abstract Number: 2042 • 2013 ACR/ARHP Annual Meeting

    Pregnancy Outcomes In Women With Rheumatologic Conditions Exposed To Infliximab

    Sirisha Kalari1, Fredrik Granath2, Chun-Yuan Guo1, Diane D. Harrison1, Gabriella Bröms2, Anja Geldhof3, Riikka Nissinen3, Marilyn Sanders1, Mika Gissler4, Lars Pedersen5, Henrik Toft Sorensen5 and Helle Kieler2, 1Janssen Research & Development, LLC., Horsham, PA, 2Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden, 3Janssen Biologics Europe, Leiden, Netherlands, 4Information Department, National Institute for Health and Welfare, Helsinki, Finland, 5Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: RA, AS, and PsA are approved indications for infliximab (IFX). In the US, IFX is a pregnancy Category B drug. For RA and some…
  • Abstract Number: 2043 • 2013 ACR/ARHP Annual Meeting

    Perinatal Exposure To Traditional and Biologic Disease Modifying Antirheumatic Drugs In Rheumatic Diseases: A Systematic Review Of Congenital Outcomes

    Corisande Baldwin1, Sharan Rai2, J. Antonio Avina-Zubieta2,3 and Mary De Vera2,4, 1Division of Rheumatology, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Centre of Canada, Richmond, BC, Canada, 3Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose:  Despite the high incidence of rheumatic diseases during reproductive years, little is known about the perinatal impact of traditional and biologic disease modifying antirheumatic…
  • Abstract Number: 2044 • 2013 ACR/ARHP Annual Meeting

    Birth Outcomes In Childbearing Women Treated With Thiopurines: A Meta-Analysis

    Zeinab F. Saleh1, Raveendhara R. Bannuru2, William F. Harvey2 and Timothy E. McAlindon3, 1Adult Rheumatology, Tufts Medical Center, Boston, MA, 2Rheumatology, Tufts Medical Center, Boston, MA, 3Division of Rheumatology, Tufts Medical Center, Boston, MA

     Background/Purpose: The thiopurines azathioprine (AZA) and 6-mercaptopurine (6-MP) are effective treatments for many rheumatic and autoimmune conditions. These medications have a category D classification from…
  • Abstract Number: 2045 • 2013 ACR/ARHP Annual Meeting

    Long QT and Hydroxychloroquine; A Poorly Recognised Problem In Rheumatology Patients

    Andra Negoescu1, Andrew Thornback2, Eugene Wong2 and Andrew J. Ostor2, 1Rheumatology, Rheumatology Research Unit, Addenbrooke's Hospital, Cambridge, United Kingdom, 2Rheumatology Research Unit, Addenbrooke's Hospital, Cambridge, United Kingdom

    Background/Purpose:      Hydoxychloroquine (HCQ) is widely used for the treatment of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) with a side-effect profile including myopathy…
  • Abstract Number: 2046 • 2013 ACR/ARHP Annual Meeting

    Lower-Dose Indomethacin Submicron Particle Capsules’ Efficacy In Acute Pain: Results From Two Phase 3 Studies

    Roy D. Altman1, Allan Gibofsky2, Mark Jaros3 and Clarence Young4, 1David Geffen School of Medicine, UCLA, Los Angeles, CA, 2Medicine and Public Health, Hospital for Special Surgery, New York, NY, 3Summit Analytical, Denver, CO, 4Iroko Pharmaceuticals, Philadelphia, PA

    Background/Purpose: Indomethacin is used to treat acute gouty arthritis and other acute pain conditions but, like other NSAIDs, is associated with dose-related gastrointestinal, cardiovascular, and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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