Abstracts Archive - Page 2227 of 2605 - ACR Meeting Abstracts

Abstract Number: 76 • 2014 ACR/ARHP Annual Meeting
Identification of Synovial Genes and Pathways Associated with Disease Progression in a Cohort of Early Symptomatic Osteoarthritis Patients Using a Transcriptomic Approach
Arjen B. Blom¹, Peter L. van Lent¹, Martijn H. van den Bosch², Hans Cats³, Frank H.J. van den Hoogen⁴, Floris P.J.G. Lafeber⁵, Wim B. van den Berg¹ and Peter M. van der Kraan¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ³Hengstdal 3, Sint Maartenskliniek, Ubbergen, Netherlands, ⁴Rheumatology, Rheumatology Centre Sint Maartenskliniek and Radboud university medical center, Ubbergen (Nijmegen), Netherlands, ⁵Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: If and how the synovial activation that is observed in over 50% of osteoarthritis (OA) patients contributes to irreversible joint pathology, is not known.…
Abstract Number: 75 • 2014 ACR/ARHP Annual Meeting
Robust Identification of Anti-TNF Non-Responders in RA from Blood
Ty Thomson, Reynald Lescarbeau, David Drubin, David Fryburg, David de Graaf, Renée Deehan, Daphna Laifenfeld and Aaron Van Hooser, Selventa, Cambridge, MA
Background/Purpose: The number of biologic therapies approved for use in treating rheumatoid arthritis (RA) has grown steadily over the past 15 years. While many patients…
Abstract Number: 74 • 2014 ACR/ARHP Annual Meeting
Influence of the Polymorphism IL1ß (-511 A/C) and IL6 (- 174 G/C) on the Activity, Radiographic Damage and Clinical Forms of Patients with Psoriatic Arthritis (PSA)
Tatiana Carranco¹, Noelia Cubino², Clara Cieza-Borrela³, Ismael Calero³, Maria Dolores Sanchez³, C. Hidalgo-Calleja⁴, Alba Quesada³, Andres Plata³, Agustin Diaz Alvarez³, Ricardo Usategui⁵, Rogelio Gonzalez⁵, C.a. Montilla-Morales⁴ and J. Del Pino-Montes⁴, ¹Reumathology, HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, ²INTERNAL MEDICINE, HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, ³HOSPITAL CLINICO UNIVERSITARIO DE SALAMANCA, SALAMANCA, Spain, ⁴University of Salamanca Hospital, Salamanca, Spain, ⁵IBSAL, SALAMANCA, Spain
Background/Purpose: PSA is a chronic inflammatory disease associated to psoriasis which affects the joints, vertebrae and enthesis. Interleukin-1 is an inflammatory cytokine. A higher expression…
Abstract Number: 73 • 2014 ACR/ARHP Annual Meeting
Frequency and Risk Factors for Recurrent Falls in Community-Dwelling Elderly: A Population-Based Prospective Cohort Study in Brazil. the São Paulo Ageing & Health (SPAH) Study
Ketty LLL Machado¹, Diogo S. Domiciano², Luana G. Machado³, Camille P. Figueiredo³, Jaqueline B. Lopes³, Valéria Caparbo³, Liliam Takayama³, Ricardo M. Oliveira⁴ and Rosa Maria Pereira³, ¹Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ²Rheumatology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ³Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴RDO Diagnosticos Medicos, São Paulo, Brazil
Background/Purpose: Falls are among the leading external causes of mortality in the elderly. This issue acquires substantial importance in low-income countries where the population’s aging…
Abstract Number: 72 • 2014 ACR/ARHP Annual Meeting
The Association Between Doctor-Diagnosed Arthritis and Falls and Fall Injuries Among Middle-Aged and Older Adults
Kamil E. Barbour¹, Louise Murphy², Kristina A. Theis³, Charles G. Helmick⁴, Jennifer Hootman⁵ and Judy A. Stevens⁶, ¹Arthritis Program, CDC, Atlanta, GA, ²Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ³Centers for Disease Control and Prevention, Atlanta, GA, Georgia, ⁴National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, ⁵Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Falls are the leading cause of injury-related morbidity and mortality among older adults (age ≥65 years), with more than one in three falling each…
Abstract Number: 71 • 2014 ACR/ARHP Annual Meeting
Prevalence of Pain Reporting in Different Ethnic Groups in the UK: Results from a Large Biobank
Marcus Beasley¹, Gareth T. Jones¹, Tatiana Macfarlane² and Gary J. Macfarlane¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Dental School, University of Aberdeen, Aberdeen, United Kingdom
Background/Purpose: Very large epidemiological studies designed to investigate genetic and environmental influences on disease, known as ‘biobanks' can be used to look at associations between…
Abstract Number: 70 • 2014 ACR/ARHP Annual Meeting
The Odds of Work Disability, Unemployment and Depending on Living Allowances Are More Influenced By the Number of Morbidities Than By the Presence of a Musculoskeletal Disease
Antje van der Zee-Neuen¹, Polina Putrik², Sofia Ramiro³, Andras Keszei⁴, Rob de Bie⁵, Astrid M. Chorus⁶ and Annelies Boonen⁷, ¹Internal Medicine, Rheumatology, Maastricht University, Maastricht, Netherlands, ²Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ³Rheumatology, Amsterdam Rheumatology Center, University of Amsterdam & Hospital Garcia de Orta, Almada, Portugal, Amsterdam, Netherlands, ⁴Medical Informatics, RWTH Aachen University, Aachen, Germany, ⁵Epidemiology, Maastricht University, Maastricht, Netherlands, ⁶Netherlands Organization for Applied Scientific Research, Leiden, Netherlands, ⁷Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: The prevalence of multimorbidity (≥ 2 chronic morbidities in 1 person), is increasingly common also in patients at working age. Musculoskeletal diseases (MSKD) are…
Abstract Number: 69 • 2014 ACR/ARHP Annual Meeting
Assessment of Exercise Status in Routine Care Using Patient Reported Outcomes: Initiating Exercise Is Associated with Better Outcomes Than No Exercise
Isabel Castrejón¹, Selda Celik², Theodore Pincus¹ and Yusuf Yazici³, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, NYU School of Medicine, New York, NY, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY
Background/Purpose: Extensive evidence indicates major benefits of exercise in rheumatoid arthritis1 and many other rheumatic diseases,2 not only for cardiovascular and general fitness, but also for…
Abstract Number: 68 • 2014 ACR/ARHP Annual Meeting
Physical Inactivity to Activity Associated with Less Decline in Physical Function
Abigail Gilbert¹, Jing Song², Pamela A. Semanik³, Rowland W. Chang⁴ and Dorothy D. Dunlop², ¹Rheumatology, Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University, Chicago, IL, ⁴Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Regular physical activity has been demonstrated to improve quality of life for adults with chronic disease including osteoarthritis. Despite these benefits, half of adults…
Abstract Number: 67 • 2014 ACR/ARHP Annual Meeting
Effects of Exercise on Depressive Symptoms in Adults with Arthritis: A Systematic Review with Meta-Analysis
George A. Kelley¹, Kristi S. Kelley¹ and Jennifer Hootman², ¹Biostatistics, West Virginia University, Morgantown, WV, ²Population Health, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Previous randomized controlled trials have led to conflicting findings regarding the effects of exercise on depressive symptoms in adults with arthritis and other rheumatic…
Abstract Number: 66 • 2014 ACR/ARHP Annual Meeting
Association of Knee Osteoarthritis and Limitations in Physical Function in a Rural Chinese Population: The Wuchuan OA Study
Xu Wu¹, Jingbo Niu², Yan Ke³, Qiang LIU⁴, Xu Tang Sr.⁵, Zhengming Cao³, Rujun Li³, Hu Li³, Kai Wang³, Xin Zhi³, Daniel White⁶ and Jian Hao Lin⁵, ¹Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China, ²Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, ³Peking University People’s Hospital, Beijing, China, ⁴Arthritis Clinical and Reserch Center, Peking University People's Hospital, Peking University Health Science Center, Beijing, China, ⁵Peking University Health Science Center, Beijing, China, ⁶Clinical Epidemiology Training, Boston Univ School of Med, Boston, MA
Background/Purpose knee osteoarthritis (OA) causes more limitations in physical function than other chronic conditions in Caucasians. Knee OA is known to be more prevalent among…
Abstract Number: 65 • 2014 ACR/ARHP Annual Meeting
Impact of Dropout and Total Knee Replacement on Joint Space Narrowing Estimation: Data from Osteoarthritis Initiaive
Jamie E. Collins and Elena Losina, Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA
Impact of dropout and TKR on Joint Space Narrowing estimation: data from Osteoarthritis InitiativeBackground/Purpose: Structural progression in knee osteoarthritis (OA) is often measured by Joint…
Abstract Number: 63 • 2014 ACR/ARHP Annual Meeting
Spine Osteoarthritis Is Associated with All Cause Mortality in Older Men
Charline Estublier¹, Roland Chapurlat² and Pawel Szulc³, ¹Rheumatology, Hôpital Edouard Herriot, Pavillon F, Lyon, France, ²Pavillon F Rheumatology, Hopital Edouard Herriot, Lyon, France, ³Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France
Background/Purpose: Hip and knee osteoarthritis (OA) was associated with higher cardiovascular morbidity and mortality. Data on the cardiovascular status in men with spine OA are…
Abstract Number: 62 • 2014 ACR/ARHP Annual Meeting
Severe Spine Osteoarthritis in Older Men Is Associated with the Risk of Incident Fragility Fracture
Roland Chapurlat¹, Charline Estublier² and Pawel Szulc³, ¹Pavillon F Rheumatology, Hopital Edouard Herriot, Lyon, France, ²Rheumatology, Hôpital Edouard Herriot, Pavillon F, Lyon, France, ³Epidemiology of Osteoporosis, INSERM UMR 1033, Lyon, France
Background/Purpose: Data on the association of osteoarthritis (OA) with bone fragility are limited. In particular, data on the fracture risk in older men with spine…
Abstract Number: 64 • 2014 ACR/ARHP Annual Meeting
Effect of Family Support on Short-and Intermediate Term Pain and Function Outcomes after Knee or Hip Replacement
Jasvinder A. Singh¹, Kenneth G. Saag², Celeste Lemay³, Jeroan Allison⁴ and Patricia D. Franklin⁵, ¹University of Alabama at Birmingham, Birmingham, AL, ²Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, ³University of Massachusetts Medical School, Worchester, MA, ⁴Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, ⁵Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA
Background/Purpose: Patients who undergo total knee replacement (TKR) and total hip replacement (THR) need significant help in the immediate post-operative period, when discharged to home.…

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