Abstracts Archive - Page 2184 of 2605 - ACR Meeting Abstracts

Abstract Number: 706 • 2014 ACR/ARHP Annual Meeting
Humoral Immunodeficiency in Patients Presenting with Clinical Features of Systemic Lupus Erythematosus
W. Winn Chatham¹, Duncan Harmon² and Harry W. Schroeder Jr.³, ¹University of Alabama at Birmingham, Birmingham, AL, ²Medicine/Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Medicine, University of Alabama-Birmingham, Birmingham, AL
Background/Purpose: Humoral immunodeficiency syndromes including common variable immune deficiency (CVID) are not uncommonly associated with autoimmunity. The spectrum of autoimmune disorders encountered in CVID patients…
Abstract Number: 705 • 2014 ACR/ARHP Annual Meeting
Lupus Chest Pain in the Emergency Department: a Common Diagnostic Dilemma
Masoom Modi¹, Mariko L. Ishimori¹, Daniel J. Wallace² and Michael Weisman¹, ¹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Rheumatology, Cedars-Sinai/David Geffen School of Medicine at UCLA, Los Angeles, CA
Background/Purpose: Chest pain (CP) is a common symptom reported by SLE patients often leading to presentation to Emergency Departments (ED). The origin of CP…
Abstract Number: 704 • 2014 ACR/ARHP Annual Meeting
Utility and Associated Risk of Pulmonary Embolism CT Scans in the Michigan Lupus Cohort
Ruba Kado¹, Emily Siegwald², Emily Lewis², Mitch Goodsitt³, Emmanuel Christodoulou³, Ella Kazerooni³ and W. Joseph McCune⁴, ¹Internal Medicine-Rheumatology, University of Michigan, Ann Arbor, MI, ²Rheumatology, University of Michigan, Ann Arbor, MI, ³Radiology, University of Michigan, Ann Arbor, MI, ⁴Internal Medicine/Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Ionizing radiation from CT scanning can increase cancer risk. Lupus patients are frequently evaluated for chest pain and may have multiple pulmonary embolism CT…
Abstract Number: 703 • 2014 ACR/ARHP Annual Meeting
Autoimmune Hepatitis in Systemic Lupus Erythematosus
Doo-Ho Lim, Seung-Hyeon Bae, Soo Min Ahn, Seokchan Hong, Yong-Gil Kim, Chang-Keun Lee and Bin Yoo, Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Background/Purpose: Autoimmune Hepatitis (AIH) is a chronic progressive liver disease of unknown cause, characterized by circulating autoantibodies and hyperglobulinemia. Patients with AIH often have other…
Abstract Number: 702 • 2014 ACR/ARHP Annual Meeting
Protein Losing Enteropathy in Systemic Lupus Erythematosus
Doo-Ho Lim, Seung-Hyn Bae, Soo Min Ahn, Seokchan Hong, Yong-Gil Kim, Chang-Keun Lee and Bin Yoo, Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Background/Purpose: Protein losing enteropathy (PLE), characterized by severe hypoalbuminemia and edema, is rare manifestation of systemic lupus erythematosus (SLE). The study was proposed to identify…
Abstract Number: 701 • 2014 ACR/ARHP Annual Meeting
How Important Is Physical Activity for Patients with Systemic Lupus Erythematodes? -Results of Lula-Study
Isabelle Kloubert¹, Gamal Chehab¹, Jutta Richter², Rebecca Fischer-Betz³, Ralph Brinks² and Matthias Schneider¹, ¹Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, ²Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany, ³Department of Rheumatology, University of Düsseldorf, Düsseldorf, Germany
Background/Purpose Physical activity (PA) plays a decisive role in primary and secondary prevention in various domains of medicine. Our examination aimed to determine association PA…
Abstract Number: 700 • 2014 ACR/ARHP Annual Meeting
Decreased Lung Diffusion Capacity in Asymptomatic Patients with Systemic Lupus Erythematosus Does Not Predict Future Lung Disease
Ofir Elalouf¹, Elizabeth Fireman², David Levartovsky¹, Ilana Kaufman¹, Ori Rogovski³, Ori Elkayam¹, Dan Caspi¹ and Daphna Paran¹, ¹Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, ²Pulmonary and Allergic diseases, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, ³Internal Medicine ward, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Background/Purpose In a previous study, performed 9±3.6 years ago 74 asymptomatic patients with systemic lupus erythematosus (SLE) and or antiphospholipid syndrome (APS) who fulfilled the…
Abstract Number: 719 • 2014 ACR/ARHP Annual Meeting
Target Modulation of a Type I Interferon (IFN) Gene Signature with Sifalimumab or Anifrolumab in Systemic Lupus Erythematosus (SLE) Patients in Two Open Label Phase 2 Japanese Trials
Chris Morehouse¹, Linda Chang², Liangwei Wang³, Philip Brohawn¹, Shinya Ueda⁴, Gabor Illei⁵, Warren Greth³, Stephen Yoo⁶, Lorin Roskos⁷, Yihong Yao⁸, Gabriel Robbie⁹ and Brandon W. Higgs¹, ¹Translational Sciences, MedImmune, LLC, Gaithersburg, MD, ²Translational Sciences, MedImmune, Hayward, CA, ³MedImmune, LLC, Gaithersburg, MD, ⁴PK, Astrazeneca, Osaka, Japan, ⁵Clinical Development, Medimmune, Gaithersburg, MD, ⁶Clinical Development, MedImmune, LLC, Gaithersburg, MD, ⁷One MedImmune Way, Medimmune, Gaithersburg, MD, ⁸Translational Sciences, MedImmune, Gaithersburg, MD, ⁹Clinical Pharmacology and DMPK, MedImmune, Gaithersburg, MD
Background/Purpose The pharmacokinetic (PK) and pharmacodynamic (PD) effects of two investigational monoclonal antibodies inhibiting type I IFN signaling - sifalimumab or anifrolumab, specific for IFN-α…
Abstract Number: 718 • 2014 ACR/ARHP Annual Meeting
Safety of Gardasil® Vaccine in Systemic Lupus Erythematosu, Trial Update
J. Patricia Dhar^1,2, Lynnette Essenmacher³, Renee Dhar^4,5, Ardella Magee⁶, Harpreet Sagar², Malini Venkatram⁷ and Robert Sokol⁸, ¹Internal Medicine, Central Michigan University College of Medicine, Saginaw, MI, ²Internal Medicine/Rheumatology, Wayne State University, Detroit, MI, ³Wayne State University, Detroit, MI, ⁴Clinical Research Center, Wayne State University, Detroit, MI, ⁵CMED medical student,, Central Michigan University College of Medicine, Mount Pleasant, MI, ⁶Clinical Research Center, Wayne State University, Detroit, MI, ⁷Division of Rheumatology, Wayne State University, Detroit, MI, ⁸Obstetrics and Gynecology, Wayne State University, Detroit, MI
Background/Purpose: Cervical neoplasia is increased in women with SLE presumably due to cervical infection with oncogenic Human Papillomavirus (HPV) types which persist in an immunosuppressed…
Abstract Number: 717 • 2014 ACR/ARHP Annual Meeting
Comparison of Responsiveness of Lupus Impact Tracker with Lupus Quality of Life to Selena Responder Index
Hervé Devilliers¹, Narender Annapureddy², Winston Sequeira³, Joel A Block⁴ and Meenakshi Jolly², ¹Dijon University Hospital, Department of internal medicine and systemic diseases, Dijon, France, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³rush university, chicago, IL, ⁴Rush University, Chicago, IL
Background/Purpose: Lupus Impact Tracker (LIT) is a 10-item patient reported outcome tool to measure the impact of Systemic Lupus Erythematosus (SLE) or its treatment on…
Abstract Number: 716 • 2014 ACR/ARHP Annual Meeting
Simple Disease Assessment for People with Lupus Erythematosus
Meenakshi Jolly¹, Winston Sequeira², Sergio Toloza³, Ana M. Bertoli⁴, Luis M. Vilá⁵, Ivana Blazevic⁶, Ioana Moldovan⁷, Karina D Torralba⁸, Berna Goker⁹, Josiane Bourré-Tessier¹⁰, Sandra V. Navarra¹¹, Daniel Wallace¹², Michael H. Weisman¹³, Ann E. Clarke¹⁴, Chi Chiu Mok¹⁵ and Joel A. Block¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Medicine/Rheumatology, Rush University, Chicago, IL, ³Hospital San Juan Bautista, San Fernando del Valle de Catamarca, Argentina, ⁴Instituto Reumatológico Strusberg, Cordoba, Cordoba, Argentina, ⁵Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, PR, ⁶University of Buenos Aires, Buenos Aries, Argentina, ⁷Rheumatology, Beaver Medical Group, Redlands, CA, ⁸University of Southern California, LA, CA, ⁹Department of Internal Medicine- Rheumatology, Gazi University School of Medicine, Ankara, Turkey, ¹⁰Department of Medicine, Division of Rheumatology, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ¹¹University of Santo Tomas Hospital, Manila, Philippines, ¹²UCLA, LA, CA, ¹³Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ¹⁴Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ¹⁵Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong
Background/Purpose: Community rheumatologists treating patients with Systemic Lupus Erythematosus (SLE) typically lack user-friendly tools to effectively track SLE disease activity. Current disease activity tools in…
Abstract Number: 715 • 2014 ACR/ARHP Annual Meeting
The REAL Life with Lupus Study: Developing a Patient Reported Outcome Measure for Use in Clinical Trials and Clinical Care
R. Paola Daly¹, Sarah Gilman², Joan T. Merrill³, Leslie M. Hanrahan⁴, Alisha Ladenburg² and Anca Askanase⁵, ¹Research & Education, Lupus Foundation of America, Washington, DC, ²Lupus Foundation of America, Washington, DC, ³Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Education & Research, Lupus Foundation of America, Washington, DC, ⁵Columbia University Medical Center, New York, NY
Background/Purpose: The goal of this study is to better understand how people with systemic lupus erythematosus (SLE) in the United States experience the disease. Results…
Abstract Number: 714 • 2014 ACR/ARHP Annual Meeting
The Validity of Patient and Physician Global Disease Activity Assessments of Systemic Lupus Erythematosus: Results from the Lupus Activity Scoring Tool (LAST) As Compared to the Selena Sledai (SS) Modification Multicentre Study
Majed Khraishi¹, Rana Aslanov², Sanjay Dixit³, Ramin Yazdani⁴, Vandana Ahluwalia⁵ and Sarah Khraishi⁶, ¹Nexus Clinical Research, St John's, NF, Canada, ²Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Rheumatology, St. Clare' Mercy Hospital, St. John's, NF, Canada, ⁵Rheumatology, William Osler Health Center, Brampton, ON, Canada, ⁶NL Research Technologies (NLRT), St. John's, NF, Canada
Background/Purpose In our centre, new tools for the assessment of SLE activity: the Lupus Activity Scoring Tool (LAST) and Clinical Lupus Activity Scoring Tool (C-LAST)…
Abstract Number: 713 • 2014 ACR/ARHP Annual Meeting
Lupuspro Is Responsive to Changes in Disease Activity over Time
David Giangreco¹, Hervé Devilliers², Narender Annapureddy¹, Joel A. Block³ and Meenakshi Jolly¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Dijon University Hospital, Department of internal medicine and systemic diseases, Dijon, France, ³Section of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Patient reported outcome (PRO) tools are important to understand, educate, manage, and follow patients with systemic lupus erythematosus (SLE). Disease targeted PRO for SLE…
Abstract Number: 712 • 2014 ACR/ARHP Annual Meeting
Mapping the Disease-Specific Lupusqol to the SF-6D
Rachel Meacock¹, Mark Harrison², Kathleen McElhone³, Janice Abbott⁴, Sahena Haque⁵, Ian N. Bruce⁶ and Lee- Suan Teh⁷, ¹Centre for Health Economics, The University of Manchester, Manchester, United Kingdom, ²University of British Columbia, Vancouver, BC, Canada, ³Royal Blackburn Hospital, Blackburn, United Kingdom, ⁴University of Central Lancashire, Preston, United Kingdom, ⁵University Hospital of South Manchester, Manchester, United Kingdom, ⁶NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, United Kingdom, ⁷Department of Rheumatology, Royal Blackburn Hospital, Blackburn, United Kingdom
Background/Purpose: The LupusQoL is a measure of health-related quality of life (HRQoL) developed specifically to assess the impact of systemic lupus erythematosus (SLE) and its…

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