ACR Meeting Abstracts

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  • Abstract Number: 2360 • 2014 ACR/ARHP Annual Meeting

    Glucocorticoids and Vascular Function in Arthritis: Benefic or Deleterious Effects? Study in Rat

    Frank Verhoeven1, Katy Maguin-Gaté2, Perle Totoson3, Daniel Wendling4 and Céline Demougeot5, 1Rheumatology, CHU jean Minjoz, Besançon, France, 2EA 4267 « Fonctions et Dysfonctions Epithéliales » , Faculté de Médecine-Pharmacie, Besançon, France, 3UFR Sciences Médicales et Pharmaceutiques, EA 4267 "Fonctions et Dysfonctions Epithéliales", besançon, France, 4Service de Rhumatologie, CHU J Minjoz, Besancon, France, 5UFR Sciences Médicales et Pharmaceutiques, EA 4267 "Fonctions et Dysfonctions Epithéliales", Besançon, France

    Background/Purpose: Rheumatoid Arthritis (RA) is associated to an increase of cardiovascular (CV) risk explained in part by an accelerated atherosclerosis as a consequence of endothelial…
  • Abstract Number: 2361 • 2014 ACR/ARHP Annual Meeting

    the Role of CD146 in the Therapeutic Potential of Mesenchymal Stem Cells in Favor of CD146+ Cells for Experimental Arthritis

    Deh-Ming Chang1 and Cheng-Chi Wu2, 1Rheumatology/Immunology, Taipei Veteran's General Hospital, Taipei, Taiwan, 2National Defense Medical Center, Taipei, Taiwan

    Background/Purpose:  To illustrate whether the subtypes of mesenchymal stem cells (MSCs) have different cellular characteristics and therapeutic potentials, we separated CD146+/- mesenchymal stem cells and…
  • Abstract Number: 2362 • 2014 ACR/ARHP Annual Meeting

    Enhanced Efficacy of Dexamethose with Synovial Fibroblast Targeted Micelles in a Collagen-Induced Arthritis Mouse Model

    Rebecca A. Bader, David R. Wilson, Arundhati Ramani and Patricia R. Wardwell, Biomedical & Chemical Engineering, Syracuse University, Syracuse, NY

    Background/Purpose:  A number of conventional, disease modifying anti-rheumatic drugs (DMARDs) are associated with severe side effects due to non-specific targeting and impaired immune function. To…
  • Abstract Number: 2363 • 2014 ACR/ARHP Annual Meeting

    Leucine-Rich Alpha-2 Glycoprotein Is a Potential Disease Activity Marker Under IL-6 Suppression in Autoimmune Arthritis

    Yusuke Takahashi1, Minoru Fujimoto2, Satoshi Serada3 and Tetsuji Naka2, 1a doctoral student, Osaka university, Suita city, Japan, 2Laboratory for immune signal, National Institute of Biomedical Innovation, Ibaraki, Japan, 37-6-8, Saito-asagi, National Institute of Biomedical Innovation, Laboratory for immune signal, Japan, Ibaraki, Japan

    Background/Purpose  C-reactive protein (CRP) is frequently used to evaluate inflammation in patients with rheumatoid arthritis (RA). However, CRP is normalized when IL-6 function is potently…
  • Abstract Number: 2364 • 2014 ACR/ARHP Annual Meeting

    PET-CT Imaging of Joints: A Quantitative Tool for Developing Novel Anti-Inflammatory Drugs

    Siba Raychaudhuri1, Anupam Mitra2, Smriti K. Raychaudhuri3 and Abhijit Chaudhari4, 1Med/Rheumatology, Univ California Davis/VA Sac, Davis, CA, 2Dermatology, VA Sacramento Medical Center, Mather, CA, 3Rheumatology, VA Sacramento Medical Center, Mather, CA, 4Radiology, UC Davis School of Medicine, Sacramento, CA

    Background/Purpose: Mouse collagen induced arthritis (CIA) is the most commonly used preclinical model to screen new drug candidates for inflammatory arthritis. The conventional read out…
  • Abstract Number: 2365 • 2014 ACR/ARHP Annual Meeting

    Comparison of the Effects of a Pharmaceutical Industry Decision Guide and Decision Aids on Patient Choice to Intensify Rheumatoid Arthritis Therapy with Etanercept

    Richard Martin1, Ryan Enck2, Andrew J. Head3, James Birmingham1 and Aaron T. Eggebeen4, 1Medicine, Rheumatology, Michigan State University, College of Human Medicine, Grand Rapids, MI, 2Michigan State University College of Human Medicine, Grand Rapids, MI, 3Medicine, Rheumatology, College of Human Medicine, Michigan State University, Grand Rapids, MI, 4Medicine, Rheumatology, Michigan State University College of Human Medicine, Grand Rapids, MI

    Background/Purpose: To evaluate the comparative effects of a pharmaceutical industry decision guide (Pharm Booklet) and International Patient Decision Aids Standard (IPDAS) compliant patient decision aids…
  • Abstract Number: 2366 • 2014 ACR/ARHP Annual Meeting

    Effectiveness, Tolerability, and Safety of Subcutaneous Methotrexate in Early Rheumatoid Arthritis: Clinical Data from the St. Gallen Cohort

    Ruediger Mueller1, Johannes von Kempis1, Michael H Schiff2 and Sarah Haile3, 1Rheumatology, St. Gallen Hospital, CH- 9007 St.Gallen, Switzerland, 2University of Colorado, Denver, CO, 3Division of Biostatistics, Institute for Social and Preventive Medicine,, University of Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: MTX is the cornerstone of RA treatment, although limitations of systemic exposure of oral MTX may affect its efficacy. Subcutaneous (SC) MTX has greater…
  • Abstract Number: 2367 • 2014 ACR/ARHP Annual Meeting

    Physician Awareness of Suboptimal Patient Adherence to MTX: Results from a Large U.S. Rheumatoid Arthritis Registry

    Jeffrey R. Curtis1, Aseem Bharat2, Lang Chen3, Jeffrey D. Greenberg4, Joel M. Kremer5 and Dimitrios A. Pappas4, 1Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Medicine, University of Alabama at Birmingham, Birmingham, AL, 4Corrona, LLC., Southborough, MA, 5Medicine, Albany Medical College and the Center for Rheumatology, Albany, NY

    Background/Purpose: Most rheumatoid arthritis (RA) registries capture information about medication use using data captured at office visits. The extent to which this information may be…
  • Abstract Number: 2368 • 2014 ACR/ARHP Annual Meeting

    Impact of Physicians’ Adherence to Treat-to-Target Strategy on Outcomes in Early Rheumatoid Arthritis

    Laura Kuusalo1, Kari Puolakka2, Hannu Kautiainen3, Marjatta Leirisalo-Repo4 and Vappu Rantalaiho5, 1Department of Internal Medicine, Division of Rheumatology, Turku University Hospital, Turku, Finland, 2Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland, 3Medcare Oy, Äänekoski, Finland, 4Department of Medicine, Division Of Rheumatology, Helsinki University Central Hospital, Helsinki, Finland, 5Department of Internal Medicine, Centre for Rheumatic Diseases,, Tampere University Hospital, Tampere, Finland

    Background/Purpose We have previously shown that in early rheumatoid arthritis (RA) remission targeted, intensive combination treatment, regardless of initial infliximab, results in remission in most…
  • Abstract Number: 2369 • 2014 ACR/ARHP Annual Meeting

    Management of Perioperative Tumor Necrosis -á Inhibitors in Rheumatoid Arthritis Undergoing Arthroplasty: A Systematic Review and Meta-Analysis

    Susan M. Goodman1, Indu Menon2, Rie Smethurst3, Paul Christos4 and Vivian P. Bykerk1, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, NY, NY, 3Education - Academic Training, Hospital for Special Surgery, NY, NY, 4Healthcare Policy and Research, Weill Cornell Medical College, NY, NY

    Background/Purpose: Tumor Necrosis Factor α inhibitors (TNFi) are widely used in patients with RA (Rheumatoid Arthritis) undergoing orthopedic surgery, yet its optimal perioperative management is…
  • Abstract Number: 2370 • 2014 ACR/ARHP Annual Meeting

    Management of Perioperative Tumor Necrosis Factor α Inhibitors in Rheumatoid Arthritis Undergoing Arthroplasty: A Systematic Review and Meta-Analysis

    Susan M. Goodman1, Indu Menon2, Rie Smethurst3, Paul Christos4 and Vivian P. Bykerk1, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, NY, NY, 3Education - Academic Training, Hospital for Special Surgery, NY, NY, 4Healthcare Policy and Research, Weill Cornell Medical College, NY, NY

    Background/Purpose: Tumor Necrosis Factor α inhibitors (TNFi) are widely used in patients with RA (Rheumatoid Arthritis) undergoing orthopedic surgery, yet its optimal perioperative management is…
  • Abstract Number: 2371 • 2014 ACR/ARHP Annual Meeting

    Efficacy of First Line Biological Monotherapy in RA: Data from the Czech Registry Attra

    Herman F. Mann1,2, Sarka Forejtova3, Katerina Jarosova4, Ladislav Senolt5, Jakub Zavada6, Michal Uher7, Karel Hejduk7 and Karel Pavelka8, 1Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, 21st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, 3Rheumatology, Institute of Rheumatology, Prague, Czech Republic, 4Na Slupi 4, Institute of Rheumatology, Prague, Czech Republic, 5Na Slupi 4, Revmatologicky ustav, Prague, Czech Republic, 6Charles University, Prague, Czech Republic, 7Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic, 8Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

    Background/Purpose: The biological disease-modifying anti-rheumatic drugs (bDMARDs) should be used for the treatment of rheumatoid arthritis (RA) in combination with conventional synthetic DMARDs (csDMARDs). However…
  • Abstract Number: 2372 • 2014 ACR/ARHP Annual Meeting

    Fatigue and Related Factors in Patients with Rheumatoid Arthritis Treated with Tocilizumab in Daily Clinical Setting

    H Corominas1, C Alegre de Miguel2, M Rodríguez-Gómez3, C Marras Fernández-Cid4, F Maceiras Pan5 and ACT-AXIS Study Group, 1Rheumatology, Hospital de Sant Joan Despí Moisès Broggi, Barcelona, Spain, 2Rheumatology, Hospital Universitari Vall d'Hebron, Barcelona, Spain, 3Rheumatology, Complejo Hospitalario Cristal Piñor, Ourense, Spain, 4Rheumatology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, 5Rheumatology, Complejo Hospitalario Arquitecto Marcide-Profesor Novoa Santos, A Coruña, Spain

    Background/Purpose: Fatigue in RA possibly resulting from alterations in the HPA axis like occurs with others RA symptoms as morning stiffness, and mood and sleep…
  • Abstract Number: 2333 • 2014 ACR/ARHP Annual Meeting

    The Natural Use of Activity Pacing in Daily Life Does Not Result in Lower Symptoms in Osteoarthritis

    Susan L. Murphy1, Anna Kratz2 and Mark P. Jensen3, 1Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI, 2Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, 3Rehabilitation, University of Washington, Seattle, WA

    Background/Purpose: To examine the how individuals naturally use the behavioral strategy of activity pacing in daily life and how its usage relates to pain and…
  • Abstract Number: 2334 • 2014 ACR/ARHP Annual Meeting

    Understanding the Experiences of Rural Community-Dwelling Older Adults in Using a New DVD-Delivered Otago Exercise Programme

    Arun Agha1, Teresa Liu-Ambrose1, Catherine Backman2 and Linda C. Li3, 1Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada, 2Department of Occupational Science & Occupational Therapy, University of British Columbia, Vancouver, BC, Canada, 3Physical Therapy, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: Arthritis is known to increase the risk of injurious falls. The home-based Otago Exercise Programme (OEP) has been shown to reduce the occurrence of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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