ACR Meeting Abstracts

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  • Abstract Number: 2410 • 2014 ACR/ARHP Annual Meeting

    Working Status and Improvements in Work Productivity over Time in an Early Rheumatoid Arthritis (ERA) Cohort

    Bindee Kuriya1, Daming Lin2, Cheryl Barnabe3, Gilles Boire4, Boulos Haraoui5, Carol Hitchon6, Shahin Jamal7, J. Carter Thorne8, Diane Tin9, Janet E. Pope10, Edward Keystone11 and Vivian P. Bykerk12, 1Rheumatology, University of Toronto, Toronto, ON, Canada, 2Mount Sinai Hospital, Toronto, ON, Canada, 3Division of Rheumatology, University of Calgary, Calgary, AB, Canada, 4Rheumatology Division, CHUS - Sherbrooke University, Sherbrooke, QC, Canada, 5Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, 6Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 7Department of Rheumatology, Vancouver Coastal Health, Vancouver, BC, Canada, 8Southlake Regional Health Centre, Newmarket, Newmarket, ON, Canada, 9The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, 10Medicine, Western University, London, ON, Canada, 11University of Toronto and Mount Sinai Hospital, Toronto, ON, Canada, 12Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: To describe working status in an ERA population in the first year of disease, and factors associated with improved work productivity.  Methods: Patients in…
  • Abstract Number: 2411 • 2014 ACR/ARHP Annual Meeting

    Assessing Treatment Durability of Infliximab in the Management of Psoriatic Arthritis and Rheumatoid Arthritis Patients in a Canadian Setting

    John Kelsall1, Algis Jovaisas2, Proton Rahman3, Dalton Sholter4, Michael Starr5, William Bensen6, Maqbool Sheriff7, Wojciech Olszynski8, Michel Zummer9, Rafat Faraawi10, Andrew Chow11, Suneil Kapur12, Emmanouil Rampakakis13, John S. Sampalis13, Francois Nantel14, Susan Otawa15, May Shawi14 and Allen J Lehman15, 1The Mary Pack Arthritis Centre, Vancouver, BC, Canada, 2194 Main Street, University of Ottawa, Ottawa, ON, Canada, 3Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 4University of Alberta, Edmonton, AB, Canada, 5Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 6St Josephs Hospital and McMaster University, Hamilton, ON, Canada, 7Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 8University of Saskatchewan, Saskatoon, SK, Canada, 9Université de Montréal, Montreal, QC, Canada, 10Medicine, McMaster University, Hamilton, ON, Canada, 11McMaster University, Hamilton and Credit Valley Hospital, Mississauga, ON, Canada, 12Rheumatology, University of Ottawa, Ottawa, ON, Canada, 13JSS Medical Research, Montreal, QC, Canada, 14Janssen Inc., Toronto, ON, Canada, 15Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: The efficacy of anti-TNF in the management of psoriatic arthritis (PsA) and rheumatoid arthritis (RA) has been demonstrated in numerous controlled clinical trials. The…
  • Abstract Number: 2412 • 2014 ACR/ARHP Annual Meeting

    Regime of Use of Rituximab in Patients with Rheumatoid Arthritis in Daily Clinical Practice

    Leticia Merino-Meléndez1, Irene Llorente2, Santos Castañeda3, Teresa Velasco2, Luis Sala-Icardo4, Rosario Garcia-Vicuña4, Alberto Garcia-Vadillo5, Juan P. López-Bote4, Jorge López-López6, Federico Herrera6, Cecilia Muñoz-Calleja6, JM Álvaro-Gracia2 and Isidoro González-Alvaro4, 1Rheumatology Department, Hospital Universitario de La Princesa, Madrid, Spain, 2Rheumatology, Hospital Universitario de La Princesa, Madrid, Spain, 3Rheumatology, Hospital Universitario de La Princesa, IISP, Madrid, Spain, 4Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 5Servicio de Reumatología, Hospital Universitario de La Princesa, Madrid, Spain, 6Immunology, Hospital Universitario de La Princesa, Madrid, Spain

    Background/Purpose: The recommended therapeutic regime for Rituximab (RTX) in Rheumatoid Arthritis (RA), according to prescribing information, includes two 1000-milligram infusions given two weeks apart, every…
  • Abstract Number: 2373 • 2014 ACR/ARHP Annual Meeting

    Compliance in the Rheumatoid Arthritis Comparison of Active Therapies Trial: Triple Vs Etanercept

    Sarah Leatherman1, Hongsheng Wu2,3, Edward Keystone4, Mary Brophy1 and James O'Dell5,6, 1MAVERIC CSPCC (151MAV), VA Boston Healthcare System, Boston, MA, 2VA Boston Healthcare System, Boston, MA, 3Computer Science and Systems, Wentworth Institute of Technology, Boston, MA, 4Mount Sinai Hospital, Toronto, ON, Canada, 5VA Nebraska-Western Iowa Health Care System, Omaha, NE, 6University of Nebraska Medical Center, Omaha, NE

    Background/Purpose In the 48-week, double-blinded, noninferiority RACAT trial, 353 methotrexate suboptimal responders were randomized to two treatment strategies, either the addition of sulfasalazine and hydroxychloroquine…
  • Abstract Number: 2374 • 2014 ACR/ARHP Annual Meeting

    Use of Hydroxychloroquine Associated with Improved Lipid Profile in Rheumatoid Arthritis Patients

    Jose Felix Restrepo1, Inmaculada del Rincon2, Emily Molina3, Daniel Battafarano4 and Agustin Escalante5, 1Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 2Medicine/Clinical Immunology, UTHSCSA, San Antonio, TX, 3Rheumatology, University of Texas Health Science Center, San Antonio, TX, 4Rheumatology, San Antonio Military Medical Center, JBSA - Ft Sam Houston, TX, 5Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX

    Background/Purpose:   Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality in rheumatoid arthritis (RA). CVD risk factor reduction, such as reducing…
  • Abstract Number: 2375 • 2014 ACR/ARHP Annual Meeting

    Should Physician Reduce patients’ Glucocorticoids to Offset the Risk of Serious Infection Event Among RA Patients Who Switched from Non-Biologic Dmards and Glucocorticoid to Biologics?

    Huifeng Yun1, Lang Chen2, George W. Reed3, Joel M. Kremer4, Jeffrey D. Greenberg5 and Jeffrey R. Curtis6, 1Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, 2Medicine, University of Alabama at Birmingham, Birmingham, AL, 3Corrona, LLC., Southborough, MA, 4Medicine, Albany Medical College and the Center for Rheumatology, Albany, NY, 5Rheumatology, New York University School of Medicine, New York, NY, 6University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose:  Glucocorticoids (GCs) and biologic disease-modifying antirheumatic drugs (DMARDs) have previously been associated with serious infection events (SIEs) among rheumatoid arthritis (RA) patients. For patients…
  • Abstract Number: 2376 • 2014 ACR/ARHP Annual Meeting

    Safety of Rapid Rituximab Infusion in Rheumatoid Arthritis in a Single Community Practice

    Rafat Faraawi1, Kelly Roth2 and Sameeka Malik3, 1564 Belmont Avenue West, K-W Musculoskeletal Research Inc, Kitchener, ON, Canada, 2K-W Musculoskeletal Research Inc., Kitchener, ON, Canada, 3KW Musculoskeletal Research Inc., Kitchener, ON, Canada

    Background/Purpose: Rituximab, a chimeric monoclonal anti-CD20 antibody, is approved to be infused over 4 hours and 15 minutes (first infusion), and 3 hours and 15…
  • Abstract Number: 2377 • 2014 ACR/ARHP Annual Meeting

    A Pilot Randomized Controlled Trial of a Tailored Smoking Cessation Intervention for Rheumatoid Arthritis Patients

    Pip Aimer1, Gareth Treharne2, Simon Stebbings3, Christopher Frampton4, Vicky Cameron1, Sandra Kirby5 and Lisa K. Stamp4, 1Medicine, University of Otago, Christchurch, Christchurch, New Zealand, 2Psychology, University of Otago, Dunedin, New Zealand, 3Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, 4Department of Medicine, University of Otago, Christchurch, Christchurch, New Zealand, 5Arthritis New Zealand, Wellington, New Zealand

    Background/Purpose Smoking adversely influences comorbidities in rheumatoid arthritis (RA) and may affect progression of RA. The combination of negative health effects makes a compelling case…
  • Abstract Number: 2378 • 2014 ACR/ARHP Annual Meeting

    Ethnic Minorities with Rheumatoid Arthritis Achieve a Meaningful Clinical Response at 12 Months Despite Infrequent Use of Biologic Therapies

    Gail S. Kerr1, Yusuf Yazici2, Christopher Swearingen3, Sharon Dowell4, Luis R. Espinoza5, Edward Treadwell6, Theresa Lawrence-Ford7, Yvonne Sherrer8, Angelia Mosley-WIlliams9, Rodolfo Perez Alamino10, Ignacio Garcia-Valladares11, Akgun Ince12, Mercedes Quinones13, Chunqiao Luo3, Adrian Godoy4 and John Amatruda14, 1Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, 2Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3Pediatrics and Biostatistics, University of Arkansas, Little Rock, AR, 4Division of Rheumatology, Howard University, Washington, DC, 5Medicine-Section of Rheum, LSU Medical Center, New Orleans, LA, 6Dept Medicine Div of Rheum, E Carolina Univ Sch of Med, Greenville, NC, 7North Georgia Rheumatology Group, PC, Lawrenceville, GA, 8Rheum/Immunology, Centre Rheum Immunol Arthritis, Fort Lauderdale, FL, 9Rheumatology, Detroit VAMC, Detroit, MI, 10internal Medicine, LSUHSC, New Orleans, LA, 11Immunology and Rheumatology, Hospital General de Occidente, Zapopan, Jal., Mexico, 12Arthitis Consultants Inc, St. Louis University, St. Louis, MO, 13Division of Rheumatology, Howard University Hospital, Washington, DC, 14Rheumatology, Howard University, Washington, DC

    Ethnic Minorities with Rheumatoid Arthritis Achieve a Meaningful Clinical Response at 12 months Despite Infrequent Use of Biologic Therapies. Background/Purpose: Ethnic minorities with rheumatoid arthritis…
  • Abstract Number: 2379 • 2014 ACR/ARHP Annual Meeting

    Minimal Radiographic Progression in RA Patients Receiving Routine Care in the Espoir Early Arthritis Cohort: Similar Prognosis According to 6 Different Remission Criteria

    Isabel Castrejón1, Maxime Dougados2, Bernard Combe3, Francis Guillemin4, Bruno Fautrel5 and Theodore Pincus1, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Université Paris René Descartes and Hôpital Cochin, Paris, France, 3Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, 4Nancy University Hospital, Nancy, France, 5Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France

    Background/Purpose Remission has become a more achievable goal in rheumatoid arthritis (RA). Several criteria for remission are available in RA, including one based on RAPID3…
  • Abstract Number: 2380 • 2014 ACR/ARHP Annual Meeting

    Durability of First Biologic Is Not Influenced By Initial/Early DAS28

    Gina Rohekar1, Binu Jacob2, Janet E. Pope3 and Claire Bombardier4, 1Rheumatology, St. Joseph's Hospital, London, ON, Canada, 2University Health Network, Toronto General Research Institute, Toronto, ON, Canada, 3Medicine, Western University, London, ON, Canada, 4Rheumatology, University of Toronto, Toronto, ON, Canada

    Background/Purpose:   The Ontario Best Practices Research Initiative (OBRI) collects data on RA treatment in a real-world setting.  Patients are enrolled and prospectively followed to…
  • Abstract Number: 2381 • 2014 ACR/ARHP Annual Meeting

    Adherence to a Treat-to-Target (T2T) Strategy in Early Rheumatoid Arthritis. Is It Feasible in Daily Clinical Practice?

    Christian A. Waimann1, Gustavo Citera2, Fernando Dal Pra3, Maria Celeste Orozco4, Federico Ceccatto5, Sergio Paira6, M Gauna7, Anastasia Secco7, M Mamani7, Lucila Marino8, Francisco Caeiro9, AC Alvarez10, Maria Haye Salinas9, L Encinas11, Javier Rosa12, Valeria Scaglioni13, Enrique R. Soriano14, Josefina Marcos15, Mercedes García15, A Salas15, Alejandro Martinez16, Rafael Chaparro del Moral17, Oscar Luis Rillo17, Horacio Berman18, Alberto Berman18, Francisco Colombres18, Edson Veloso19, Ricardo V. Juárez20, Maria Elena Crespo21, Ana Quinteros22, M Leal22, Gabriela Salvatierra23, C Ledesma23, Mónica P. Sacnun24, R Quintana25 and Marcelo Abdala26, 1Rheumatology, Hospital Olavarria, Olavarria, Argentina, 2Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 4Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 5Rheumatology, Hospital Jose María Cullen, Santa Fé, Argentina, 6Section of Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, 7Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, 8Rheumathology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, 9Reumatología, Hospital Privado de Córdoba, Córdoba, Argentina, 10Hospital Privado Centro Médico de, Córdoba, Argentina, 11Rheumatology, Hospital Privado Centro Medico De Córdoba, Cordoba, Argentina, 12Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 13Rheumatology Unit, Internal Medical Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 14Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 15HIGA San Martín, La Plata, Argentina, 16Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 17Rheumatology Section, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 18Centro Medico Privado de Reumatologia, Tucumán, Argentina, 19Sanatorio y Universidad Adventista Del Plata, Entre Rios, Argentina, 20Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, 21Hospital Señor Del Milagro, Salta, Argentina, 22Centro Integral de Reumatología, Tucumán, Argentina, 23Instituto Provincial De Rehabilitación Integral, Stgo. del Estero, Argentina, 24Hospital Provincial, Rosario, Argentina, 25Hospital provincial, Rosario, Argentina, 26Hospital Provincial del Centenario, Santa Fe, Argentina

    Background/Purpose :  The treat-to-target (T2T) strategy has become the new paradigm for the treatment of Rheumatoid Arthritis (RA); however the question is whether this strategy…
  • Abstract Number: 2382 • 2014 ACR/ARHP Annual Meeting

    Adherence to Dmards in the First Six Months of Treatment in Early Arthritis Patients; Comparing Three Adherence Measures

    Annelieke Pasma1, Ethan den Boer2, Adriaan van 't Spijker3, Reinier Timman3, Jan van Busschbach3 and J.M.W. Hazes4, 1Rheumatology, Erasmus MC University Medical Center, Rotterdam, Netherlands, 2Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, Netherlands, 3Psychiatry, section Medical Psychology and Psychotherapy, Erasmus MC University Medical Center, Rotterdam, Netherlands, 4Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands

    Background/Purpose Non-adherence to DMARDs is an important indicator for the effectiveness of treatment in early arthritis patients. Reported non-adherence rates differ widely, because studies use…
  • Abstract Number: 2383 • 2014 ACR/ARHP Annual Meeting

    The 12-Years Retention Rate of the First-Line TNF-Inhibitor in the Treatment of Rheumatoid Arthritis: Real-Life Data from a Local Registry

    Ennio Giulio Favalli1, Martina Biggioggero2, Francesca Pregnolato3, Andrea Becciolini2, Alessandra Emiliana Penatti2, Antonio Marchesoni4 and Pier Luigi Meroni2, 1Department of Rheumatology, Gaetano Pini Institute, Milan, Italy, 2Chair and Division of Rheumatology, Gaetano Pini Institute, University of Milan, Milan, Italy, 3Experimental Laboratory of Immunological and Rheumatologic Researches, IRCCS, Istituto Auxologico Italiano, Milan, Italy, 4Rheumatology, Department of Rheumatology, Gaetano Pini Institute, Milan, Italy

    Background/Purpose Data on over-10-years drug survival of TNF inhibitors (TNFi) are still lacking. The aim of the study is to analysed the long-term retention rate…
  • Abstract Number: 2384 • 2014 ACR/ARHP Annual Meeting

    Factors Associated with Methotrexate Treatment Duration, Including Subcutaneous Use, in Patients with Rheumatoid Arthritis: Observations from the VA Database

    Bernard Ng, Rheumatology, U.S. Department of Veterans' Affairs- Puget Sound Healthsystem, Seattle, WA

    Background/Purpose: A previous analysis of RA patients in national administrative databases of the Department of Veterans Affairs (VA) suggested that injectable MTX was associated with…
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