Abstracts Archive - Page 1794 of 2425 - ACR Meeting Abstracts

Abstract Number: 1574 • 2015 ACR/ARHP Annual Meeting
Associations of Serum Anti-Malondialdehyde-Acetaldehyde (MAA) Antibodies with Cardiovascular and Respiratory Mortality in Men with Rheumatoid Arthritis
Bryant R. England¹, Geoffrey M. Thiele², Michael J. Duryee³, Lynell Klassen⁴, Jeremy Sokolove⁵, William H. Robinson⁶, Daniel Anderson⁷, Harlan Sayles⁷, Kaleb Michaud⁸, Liron Caplan⁹, Lisa A. Davis⁹, Grant W. Cannon¹⁰, Brian Sauer¹¹, E. Blair Solow¹², Andreas Reimold¹³, Gail S. Kerr¹⁴, Pascale Schwab¹⁵, Joshua F. Baker¹⁶ and Ted R. Mikuls¹⁷, ¹Division of Rheumatology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ²Research Services 151, Omaha VA Medical Center, Omaha, NE, ³Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁴Dept of Internal Medicine, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Division of Immunology and Rheumatology, Stanford University Medical Center, Mountain View, CA, ⁶Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁷University of Nebraska Medical Center, Omaha, NE, ⁸Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, ⁹Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, ¹⁰Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ¹¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ¹²Rheumatology, UT Southwestern Medical Center, Dallas, TX, ¹³Rheumatology, VAMC, University of Texas Southwestern Medical Center, Dallas, TX, ¹⁴VAMC, Georgetown University, Washington, DC, ¹⁵Div Arth & Rheum Dis, Oregon Health & Sci Univ OP09, Portland, OR, ¹⁶Rheumatology, University of Pennsylvania, Philadelphia, PA, ¹⁷Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Mortality from cardiovascular (CV) and respiratory causes is increased in rheumatoid arthritis (RA). Predictive serologic biomarkers of these events are lacking. Previously, we have…
Abstract Number: 1575 • 2015 ACR/ARHP Annual Meeting
Serum Vascular Cell Adhesion Molecule-1 (VCAM-1) Levels Are Associated with Vascular Dysfunction and Increased Cardiovascular Risk in an Animal Model and Patients with Rheumatoid Arthritis
Ruth Davies¹, Daniela Iacono², Lauren A. Jordan¹, Jessica O Williams¹, Charlotte Rawlings¹, Derek Lang³, Anwen S. Williams¹ and Ernest H. Choy¹, ¹Cardiff University, Institute of Infection and Immunity, Tenovus Building, University Hospital of Wales, Cardiff, United Kingdom, ²Department of Clinical and Experimental Medicine. Rheumatology Section. Second University of Naples, Naples, Italy, ³Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine, Cardiff, United Kingdom
Background/Purpose: Mortality is increased in Rheumatoid arthritis (RA) patients mainly due to cardiovascular (CV) disease; however the biologic mechanisms are unknown. Increased CV risk in…
Abstract Number: 1576 • 2015 ACR/ARHP Annual Meeting
Effect of Conventional Synthetic and Biological Disease Modifying Anti-Rheumatic Drugs on the Immunogenicity of Hepatitis B Vaccine in Patients with Rheumatoid Arthritis
Samanan Intongkam¹, Rattapol Pakchotanon², Sumapa Chaiamnuay², Paijit Asavatanabodee² and Pongthorn Narongroeknawin², ¹Internal medicine, Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand, ²Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand
Background/Purpose: Immunogenicity of pneumococcal and influenza vaccine in patients with rheumatoid arthritis (RA) have been assessed in many studies. However, the humoral immune response of…
Abstract Number: 1577 • 2015 ACR/ARHP Annual Meeting
Periodontal Evaluation Is Associated with Increased Likelihood of Achieving Low Disease Activity in Rheumatoid Arthritis with Methotrexate
Melanie Rohr¹, James R. O'Dell¹, Abhijeet Danve², Harlan Sayles¹, Geoffrey M. Thiele³, Jeffrey Payne⁴ and Ted R. Mikuls⁵, ¹University of Nebraska Medical Center, Omaha, NE, ²Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³Research Services 151, Omaha VA Medical Center, Omaha, NE, ⁴College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ⁵Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Rheumatoid arthritis (RA) outcomes have improved substantially due to the development of new drug therapies, but also due to emphasis on early aggressive MTX…
Abstract Number: 1578 • 2015 ACR/ARHP Annual Meeting
Serum Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Antibody Are Associated with Subclinical Interstitial Lung Disease in the Multi-Ethnic Study of Atherosclerosis: A Population-Based Study
Elana J. Bernstein¹, R. Graham Barr², John H.M. Austin³, Steven M. Kawut⁴, Ganesh Raghu⁵, Jessica L. Sell⁶, Eric A. Hoffman⁷, John D. Newell Jr.⁸, Jubal R. Watts Jr.⁹, P. Hrudaya Nath¹⁰, Sushil K. Sonavane⁹, Joan M. Bathon¹, Darcy S. Majka¹¹ and David J. Lederer², ¹Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ²Medicine, Columbia University College of Physicians & Surgeons, New York, NY, ³Radiology, Columbia University College of Physicians & Surgeons, New York, NY, ⁴Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, PA, ⁵University of Washington, Seattle, WA, ⁶Columbia University College of Physicians & Surgeons, New York, NY, ⁷University of Iowa, Iowa City, IA, ⁸Radiology, University of Iowa, Iowa City, IA, ⁹Radiology, University of Alabama at Birmingham, Birmingham, AL, ¹⁰University of Alabama at Birmingham, Birmingham, AL, ¹¹Division of Rheumatology, Northwestern University, Chicago, IL
Background/Purpose: Approximately 30% of adults diagnosed with interstitial lung disease (ILD) have an underlying established autoimmune disease. Based on the strong links between autoimmunity and…
Abstract Number: 1579 • 2015 ACR/ARHP Annual Meeting
Association of Myocardial Abnormalities with N-Terminal Pro-Brain Natriuretic Peptide and Disease Activity in Rheumatoid Arthritis without Cardiac Symptoms, Assessed By Cardiac Magnetic Resonance Imaging
Hitomi Kobayashi¹, Yasuyuki Kobayashi², Isamu Yokoe³, Natsumi Ikumi^4,5, Hirotake Inomata⁶, Atsuma Nishiwaki⁶, Noboru Kitamura¹, Kaita Sugiyama⁶, Hidetake Shiraiwa⁶, Masataka Nozaki⁶, Yosuke Nagasawa⁶, Yoshihiro Matsukawa⁵ and Masami Takei¹, ¹Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ³Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ⁴Nihon University School of Medicine, Shinjuku, Japan, ⁵Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁶Nihon University School of Medicine, Tokyo, Japan
Background/Purpose: Rheumatoid arthritis (RA) is a multi-organ inflammatory disorder associated with high cardiovascular morbidity and mortality. Cardiac involvements are typically clinically silent, only manifesting as…
Abstract Number: 1580 • 2015 ACR/ARHP Annual Meeting
Abnormal High Density Lipoproteins in Synovial Fluid from Patients with Rheumatoid Arthritis Compared to Patients with Non-Inflammatory Arthritis
Christina Charles-Schoeman¹, Yuen Yin Lee², Ani Shahbazian¹, David Meriwether³, Peter Kim² and Srinivasa T. Reddy⁴, ¹Medicine-Rheumatology, University of California Los Angeles, Los Angeles, CA, ²Medicine- Rheumatology, University of California Los Angeles, Los Angeles, CA, ³Medicine- Cardiology, University of California Los Angeles, Los Angeles, CA, ⁴Medicine-Cardiology, University of California Los Angeles, Los Angeles, CA
Background/Purpose: High levels of rheumatoid arthritis (RA) disease activity have been associated with abnormal function of circulating high density lipoproteins (HDL) and increased cardiovascular…
Abstract Number: 1581 • 2015 ACR/ARHP Annual Meeting
Cardiac Involvement in Patients with Amyloid a Amyloidosis Due to Rheumatoid Arthritis
Daisuke Kobayashi¹, Satoshi Ito¹, Yoko Wada², Akira Murasawa¹, Ichiei Narita² and Kiyoshi Nakazono¹, ¹Niigata Rheumatic Center, Shibata, Japan, ²Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Background/Purpose: Rheumatoid arthritis (RA) is one of the major causes of amyloid A (AA) amyloidosis, the major organs affected being the kidneys and gastrointestinal (GI)…
Abstract Number: 1582 • 2015 ACR/ARHP Annual Meeting
Joint Damage Associated with Loss of Body Mass in Rheumatoid Arthritis
Jose Felix Restrepo¹, Inmaculada del Rincon², Daniel Battafarano³ and Agustin Escalante⁴, ¹Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, ³Rheumatology, San Antonio Military Medical Center, JBSA - Ft Sam Houston, TX, ⁴Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: Body mass index (BMI) is a predictor of long-term outcome in rheumatoid arthritis and has been associated with joint damage. Our objective was to examine…
Abstract Number: 1583 • 2015 ACR/ARHP Annual Meeting
Identifying Risk Factors for Progression of Rheumatoid Arthritis-Associated Interstitial Lung Disease
Yashaar Chaichian¹, Dina Bassiri², Imre Noth³, Mary Strek³, Tammy Utset¹ and Rekha Vij³, ¹Medicine, Section of Rheumatology, University of Chicago Medical Center, Chicago, IL, ²Statistical & Applied Research, ACT, Inc., Iowa City, IA, ³Medicine, Section of Pulmonary/Critical Care, University of Chicago Medical Center, Chicago, IL
Background/Purpose: Interstitial lung disease (ILD) is recognized as a frequent extra-articular manifestation of rheumatoid arthritis (RA) associated with significant morbidity and mortality. Nevertheless, risk factors…
Abstract Number: 1584 • 2015 ACR/ARHP Annual Meeting
Metabolic Syndrome Is Associated with Disease Activity in Patients with Rheumatoid Arthritis: A Prospective Cohort Study
Pongchirat Tantayakom¹, Ajchara Koolvisoot¹, Emvalee Arromdee¹, Praveena Chiowchanwisawakit¹, Chayawee Muangchan¹ and Wanruchada Katchamart², ¹Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, ²Medicine, Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Background/Purpose: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease involving articular and extra-articular systems, including cardiovascular (CVS), respiratory, as well as hematologic systems, etc.…
Abstract Number: 1585 • 2015 ACR/ARHP Annual Meeting
Vaccination Uptake in Patients with Rheumatoid Arthritis Treated with Disease-Modifying Anti-Rheumatic Drug Therapy: A Retrospective Cohort Study Using UK Primary Care Electronic Medical Records
Ruth Costello¹, Kevin L. Winthrop², Stephen R Pye¹ and William G Dixon³, ¹Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ²Oregon Health and Science University, Portland, OR, ³Manchester Academic Health Sciences Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose: The guidelines for the management of rheumatoid arthritis (RA) recommend an annual influenza vaccine and a pneumonia vaccination (EULAR, 2011), prior to starting disease-modifying…
Abstract Number: 1586 • 2015 ACR/ARHP Annual Meeting
Weight Loss in Obese Rheumatoid Arthritis (RA) Patients Improves Disease Activity without Modifying RA Treatment
Elisa Gremese¹, Maria Rita Gigante¹, Barbara Tolusso¹, Anna Laura Fedele¹, Silvia Canestri¹, Barbara Aquilanti², Clara Di Mario¹, Luca Petricca¹, Stefano Alivernini¹ and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Dietology Service, Association Columbus, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: Obesity is recognized as a systemic, low-grade inflammatory state and the adipose tissue as an endocrine organ releasing pro-inflammatory cytokines. On the other hand,…
Abstract Number: 1587 • 2015 ACR/ARHP Annual Meeting
Deriving a Comorbidity Index Form the Meddra Classification: Performance of Rheumatic Disease Comorbidity Index, Charlson-Deyo Index and Functional Comorbidity Index Among Patients with RA in NOR-DMARD Cohort
Polina Putrik¹, Sofia Ramiro², Elisabeth Lie³, Andras Keszei⁴, Tore K. Kvien⁵, Till Uhlig⁶ and Annelies Boonen⁷, ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Epidemiology, Maastricht University, Maastricht, Netherlands, ⁵Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Diakonhjemmet Hospital, Oslo, Norway, ⁷Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Comorbidities have an important impact on outcomes in chronic diseases. A new and simple to compute index, the Rheumatic Disease Comorbidity Index (RDCI), has…
Abstract Number: 1588 • 2015 ACR/ARHP Annual Meeting
Increased Fracture Risk in Patients with Early Rheumatoid Arthritis: A Prospective General Population-Matched Cohort Study
Britt-Marie Nyhäll-Wåhlin¹, Sofia Ajeganova², Ingemar F Petersson³ and Maria LE Andersson⁴, ¹Department of Rheumatology, Falun Hospital, Falun, Sweden, ²Rheumatology unit, Department of Medicine,, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden, ³Lund University, Department of Orthopedics, Clinical Sciences Lund, Lund, Sweden, ⁴R&D Centre Spenshult, Halmstad, Halmstad, Sweden
Background/Purpose: Fragility fractures represent one of the serious extra-articular manifestations of rheumatoid arthritis (RA). The aim of this study was to investigate whether fracture incidence…

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