ACR Meeting Abstracts

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  • Abstract Number: 774 • 2015 ACR/ARHP Annual Meeting

    Anti-Nuclear Antibodies Have High Sensitivity for Systemic Lupus Erythematosus: Results of a Systematic Literature Review and Meta-Regression of Diagnostic Data

    Nicolai Leuchten1, Ralph Brinks2, Annika Hoyer3, Monika Schoels4, Martin Aringer1, Sindhu R. Johnson5, David I. Daikh6, Thomas Dorner7, George Bertsias8 and on behalf of the SLE Classification Criteria Steering Committee, 1Medicine III, University Medical Center and Faculty of Medicine at the TU Dresden, Dresden, Germany, 2Hiller Center for Research in Rheumatology, Duesseldorf, Germany, 3Institute for Biometry and Epidemiology, German Diabetes Center, Duesseldorf, Germany, 42nd Department of Medicine, Hietzing Hospital, Vienna, Austria, 5Dept of Rheumatology, Toronto Western and Mt. Sinai Hospitals, University of Toronto, Toronto, ON, Canada, 6Rheumatology, UCSF/VA Medical Center, San Francisco, CA, 7Charité University Medicine Berlin, Berlin, Germany, 8Rheumatology, Clinical Immunology, and Allergy, University of Crete, Heraklion, Greece

    Background/Purpose: EULAR and ACR have jointly funded a project to improve existing SLE classification criteria, aiming at earlier and more accurate classification of the disease.…
  • Abstract Number: 775 • 2015 ACR/ARHP Annual Meeting

    Identification of Candidate Items for Revised Classification Criteria for Systemic Lupus Erythematosus

    Gabriela Schmajuk1, Bimba F. Hoyer2, Martin Aringer3, Sindhu R. Johnson4, Thomas Dorner5, David I. Daikh6 and SLE Classification Criteria Steering Committee, 1San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA, 2Charité University Medicine, Department of Medicine/Rheumatology and Clinical Immunology and German Rheumatism Research Centre Berlin (DRFZ), Berlin, Germany, 3Rheumatology, Medicine III, University Clinical Center, Technical University Dresden, Dresden, Germany, 4Dept of Rheumatology, Toronto Western and Mt. Sinai Hospitals, University of Toronto, Toronto, ON, Canada, 5Charité – Universitätsmedizin, Berlin, Germany, 6Rheumatology, UCSF/VA Medical Center, San Francisco, CA

    Background/Purpose: EULAR and ACR have jointly funded a project to improve existing classification criteria for SLE; this abstract reports on the early phase of this…
  • Abstract Number: 776 • 2015 ACR/ARHP Annual Meeting

    Sensitivity of Antinuclear Antibody By Immunofluorescence Testing for Detection of Anti-Ro/SSA Antibodies

    Ivan Alcantara-Arreola1, Nina Tello-Winniczuk2 and Alejandro Diaz-Borjon3, 1Hospital Angeles Lomas, Huixquilucan, Mexico, 2Division of Internal Medicine / Rheumatology, Hospital Angeles Lomas, Huixquilucan, Mexico, 3Med/Div of Rheumatology, Hospital Angeles Lomas, Huixquilucan, Mexico

    Background/Purpose: A positive ANA test is a diagnostic criterion for several rheumatic diseases, although it may appear in other autoimmune disorders and healthy individuals. An…
  • Abstract Number: 777 • 2015 ACR/ARHP Annual Meeting

    SLE-KeyTM Rule-out Test to Assess Lupus in Anti-Nuclear Antibody Positive Subjects Using the Immunarray iCHIP®

    D. Scott Batty1, I.R. Cohen2, Chaim Putterman3, Nicole Jordan4, Keren Jakobi5, Rachel Sorek5, Yakov Blumenstein5, Pennina Safer5 and David Pisetsky6, 1ImmunArray Inc., Richmond, VA, 2Weizmann Institute of Science, Rehovot, Israel, 3Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, 4Montefiore Medical Center, New York, NY, 5ImmunArray LTD, Rehovot, Israel, 6Duke University Medical Center and Durham VAMC, Durham, NC

    Background/Purpose: SLE is associated with a broad spectrum of autoantibodies, but currently there is no single serologic test to diagnose SLE definitively.  Diagnosis is thus…
  • Abstract Number: 778 • 2015 ACR/ARHP Annual Meeting

    Associations Between Autoantibodies and Clinical Manifestations in Systemic Lupus Erythematosus: Data from a Multiethnic Latin American Cohort

    Manuel Ugarte-Gil1,2, Daniel Wojdyla3, Ignacio Garcia-Valladares4, Rocio V. Gamboa-Cardenas1, Yelitza Gonzalez-Bello5,6, Guillermo J. Pons-Estel7, Cesar A. Pastor-Asurza1,8, Ignacio Garcia-De La Torre9,10, Graciela S. Alarcon11, Bernado Pons-Estel12 and GLADEL (Grupo Latinoamericano de Estudio de Lupus), 1Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 2Universidad Cientifica del Sur, Lima, Peru, 3Universidad Nacional de Rosario, Argentina, Rosario, Argentina, 4Centro de Estudios de Investigación Básica y Clínica, SC., Guadalajara, Jalisco, Mexico, 5Immunology and Rheumatology, Hospital General de Occidente, Secretaria de Salud Jalisco, Guadalajara, Jalisco, Mexico, 6Immunology and Rheumatlogy, Universidad de Guadalajara, Zapopan, Jalisco, Mexico, 7Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain, 8Universidad Nacional Mayor de San Marcos, Lima, Peru, 9Immunology and Rheumatology, Hospital General de Occidente, Secretaria de Salud Jalisco, Zapopan, Jalisco, Mexico, 10Universidad de Guadalajara, Guadalajara, Jalisco, Mexico, 11Medicine, University of Alabama at Birmingham, Birmingham, AL, 12Hospital Provincial de Rosario, Rosario, Argentina

    Background/Purpose: Analyses of the association between autoantibodies and SLE clinical manifestations using cluster analyses assume that centroid and within-cluster residuals are similar inside the cluster…
  • Abstract Number: 779 • 2015 ACR/ARHP Annual Meeting

    Mapping Perceptions of Medication Decision Making Facilitators: The Importance of Patient Context

    Haiyan Qu1, Jinoos Yazdany2, W. Winn Chatham3, Ricahrd Shewchuk4 and Jasvinder A. Singh1, 1University of Alabama at Birmingham, Birmingham, AL, 2University of California, San Francisco, San Francisco, CA, 3Medicine/Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4University fo Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Our objective was to derive a cognitive map of how stakeholders perceive patient-identified facilitators to establish a theoretical framework for the purpose of developing…
  • Abstract Number: 780 • 2015 ACR/ARHP Annual Meeting

    Long-Term Prognosis and Factors Associated with Damage Accrual in Japanese Patients with Systemic Lupus Erythematosus

    Yoko Wada1, Hisashi Hasegawa2, Takeshi Kuroda3, Masaaki Nakano4 and Ichiei Narita1, 1Department of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, 2Division of Clinical Nephrology and Rheumatology, Niigata City General Hospital, Niigata, Japan, 3Health Administration Center, Niigata University, Niigata, Japan, 4Department of Medical Technology, School of Health Sciences, Faculty of Medicine, Niigata University, Niigata, Japan

    Background/Purpose: Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterized by fluctuating disease activity over periods of years. The estimated 5-year survival rate of…
  • Abstract Number: 781 • 2015 ACR/ARHP Annual Meeting

    Anti-Nucleosome Antibodies Versus Anti-DNA Antibodies in the Diagnosis and Monitoring of Activity of Systemic Lupus Erytematosus

    Helena Borrell Paños1, Javier Narváez2, Jordi Bas3, Eulàlia Armengol1, Maria Aparicio1, Maria Pascual1, Mercè López de Recalde1 and Joan Miquel Nolla1, 1Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Immunology Department. Hospital Universitari de Bellvitge, Barcelona, Spain

    Background/Purpose: Recently, the study of anti-nucleosome antibodies (ANUCs) has been suggested that they may be useful in the diagnosis of systemic lupus erythematosus (SLE) and in…
  • Abstract Number: 782 • 2015 ACR/ARHP Annual Meeting

    A Proposal for Assessing Systemic Lupus Erythematosus Activity By a Multimodal Instrument That Includes Clinical Variables, Physician Assessment and Modification of Treatment

    Francisco Espinoza Sr.1 and K Kalunian2, 1Rheumatology Department, Division of Internal Medicine, School of Medicine, University of Los Andes, Santiago, Chile, 2UCSD School of Medicine, La Jolla, CA

    Background/Purpose: Assessment of systemic lupus erythematosus (SLE) is complex due to its heterogeneous manifestations and its fluctuant clinical course. Current instruments stressed one specific aspect…
  • Abstract Number: 783 • 2015 ACR/ARHP Annual Meeting

    Osteonecrosis in Systemic Lupus Erythematosus: Predictive Factors

    Nimrit Dhillon1, Dafna Gladman1, Jiandong Su1 and Murray Urowitz1,2, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, U of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: We recently reported the frequency of symptomatic osteonecrosis (ON) among systemic lupus erythematosus (SLE) patients of the lupus cohort to be 13.6% The aim…
  • Abstract Number: 784 • 2015 ACR/ARHP Annual Meeting

    Electronic Health Record (EHR) As a Powerful Tool to Establish Clinical Research Lupus Cohorts

    Srilatha Kothandaraman1, Frederick Ramsey2, David Fleece3, Aaron Sorenson2, Lai Ping4, Srikanth Mukkera1, King Goh1 and Roberto Caricchio5, 1Rheumatology, Temple University, Philadelphia, PA, 2Clinical Sciences, Temple University, Philadelphia, PA, 3Pediatrics, Temple University, Philadelphia, PA, 4Temple University, Philadelphia, PA, 5Medicine, Rheumatology, Temple University, Philadelphia, PA

    Background/Purpose: Enhancing a typical EHR through implementation and utilization of research-validated instruments is termed Electronic Data Capture (EDC). EDC is found to be more efficient…
  • Abstract Number: 785 • 2015 ACR/ARHP Annual Meeting

    Further Validation of Simple Index As a Simple Disease Activity Assessment Tool for SLE

    Nisarg Gandhi1, Meenakshi Jolly2, Alana Nevares3 and Winston Sequeira1, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL, 3Internal Medicine, Cook County Hospital, Chicago, IL

    Background/Purpose: An easy, quick tool, requiring minimal training or physician input for disease activity (DA) assessment in SLE, would have potentially greater uptake for routine…
  • Abstract Number: 786 • 2015 ACR/ARHP Annual Meeting

    Anti-Carbamylated Protein Antibodies Identify Systemic Lupus Erythematosus Patients with Erosive Arthritis: Analysis of a Regional Swedish Register

    Alf Kastbom1, Philip Wallin2, Michael Ziegelasch1, Thomas Skogh1, Leendert Trouw3 and Christopher Sjöwall1, 1Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, 2Linköping University, Clinical and Experimental Medicine, Sweden, Rheumatology/AIR, Linköping, Sweden, 3Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Articular manifestations affect a majority of patients with systemic lupus erythematosus (SLE), at least at some time during the disease course. Several investigators have…
  • Abstract Number: 787 • 2015 ACR/ARHP Annual Meeting

    Validation of Lupuspro V1.8, Disease Targeted Patient Reported Outcome for Systemic Lupus Erythematosus

    Meenakshi Jolly1, Nisarg Gandhi2, Alana Nevares3 and Winston Sequeira2, 1Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL, 2Rheumatology, Rush University Medical Center, Chicago, IL, 3Internal Medicine, Cook County Hospital, Chicago, IL

    Background/Purpose: Disease Specific Patient reported outcome measure tools capture unique domains relevant to patients with a specific disease. LupusPRO is targeted towards measuring health (HRQOL)…
  • Abstract Number: 788 • 2015 ACR/ARHP Annual Meeting

    Identification of Molecular Biomarkers to Distinguish Systemic Lupus Erythematosus with Skin Involvement from Discoid Lupus Erythematosus and Subacute Cutaneous Erythematosus: Provisional Results from Cross-Sectional Studies

    Matteo Cesaroni1, Jarrat Jordan1, Jessica Schreiter1, Marc Chevrier1, Grace Wang2, Cesar Calderon3, Alexa Piantone2, Ian Gourley4, Stanley Cohen5, Scott Fretzin6, Anna Wozniacka7, Victoria P. Werth8 and Jacqueline Benson1, 1Estrela Lupus Venture, Janssen Research and Development, LLC., Spring House, PA, 2Janssen Research and Development, Spring House, PA, 337 Derwen Dr., Janssen Research and Development, Havertown, PA, 41329 Anthony Wayne drive, Janssen Research and Development, Wayne, PA, 5Metroplex Clinical Research Center, LLC, Dallas, TX, 6Dawes Fretzin Clinical Research Group, LLCC, Indianapolis, IN, 7Medical University of Lodz, Lodz, Poland, 8Philadelphia VA Medical Center, Philadelphia, PA

    Background/Purpose: Sub-classification of Lupus Erythematosus (LE) patients is largely based on defined clinical criteria while biological factors associating with or contributing to these clinical features…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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