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  • Abstract Number: 457 • 2015 ACR/ARHP Annual Meeting

    RA Patients with Medicare Only Insurance Have Similar Clinical Outcomes As Patients with Private Insurance Despite Having Less Access to Biologics

    Marcia S. Genta1, Amnon Sonnenberg2 and Robert M. Genta3, 1Dallas Arthritis Center, Dallas, TX, 2Medicine - Gastroenterology, Portland VAMC - Oregon Health & Science University, Portland, OR, 3Laboratory, Dallas Arthritis Center, Dallas, TX

    Background/Purpose: We have previously shown that patients with Medicare only coverage without financial assistance from foundations were significantly less likely to receive Biologics than patients…
  • Abstract Number: 458 • 2015 ACR/ARHP Annual Meeting

    First Year Canadian Experience with Subcutaneous Abatacept in Routine Practice for the Treatment of Patients with Rheumatoid Arthritis: Data from the Orencia Response Program (ORP) Network

    Boulos Haraoui1, Louis Coupal2, Radmila Day3, Lionel Budry4 and Youb Chalabi5, 1Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 2Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 3None, Montreal, QC, Canada, 4Bristol Myers Squibb Canada, St-Laurent, QC, Canada, 5Bristol Myers Squibb, Montreal, QC, Canada

    Background/Purpose: The subcutaneous (SC) formulation of abatacept (ABA) has been available in Canada since January 2014. Here we report first year experience with SC ABA…
  • Abstract Number: 459 • 2015 ACR/ARHP Annual Meeting

    The Effect of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Positivity on Drug Survival of Abatacept in Patients with Rheumatoid Arthritis in Routine Care: The Results from Turkbio Registry

    Ihsan Ertenli1, Omer Karadag1, Yavuz Pehlivan2, Ediz Dalkilic3, Ahmet Mesut Onat4, Bunyamin Kisacik5, Gercek Can6, Servet Akar7, Sedat Capar8, Umut Kalyoncu1, Mustafa Ferhat Oksuz9, Emine Figen Tarhan7 and Nurullah Akkoc6, 1Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Department of Rheumatology, Uludag University Faculty of Medicine, Bursa, Turkey, 3Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, 4Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Rheumatology Department, Gaziantep University School of Medicine, Gaziantep, Turkey, 6Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey, 7Department of Internal Medicine, Division of Rheumatology, Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 8Dokuz Eylül University Faculty of Statistics, Izmir, Turkey, 9Rheumatology, Uludag University Faculty of Medicine, Bursa, Turkey

    Background/Purpose: Abatacept (ABA) is a biological anti-rheumatic drug used in Rheumatoid Arthritis (RA). In TURKBIO, Turkish Biologic Registry, data on patient characteristics, diagnosis, previous treatment…
  • Abstract Number: 460 • 2015 ACR/ARHP Annual Meeting

    Changes in Body Composition and Metabolic Profile during Treatment with Tocilizumab in Patients with Rheumatoid Arthritis

    Anne Tournadre1, Bruno Pereira2, Frederic Dutheil3, Vincent Sapin4, Charlotte Giraud5, Sandrine Malochet-Guinamand6, Thomas Frayssac7, Sylvain Mathieu5, Jean-Jacques Dubost8 and Martin Soubrier8, 1Rheumatology, UNH-UMR 1019 INRA University of Auvergne and Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 2Biostatistics unit (DRCI), CHU Clermont-Ferrand, Clermont-Ferrand, France, 3Preventive and Occupational Medicine, CHU G. Montpied Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions EA3533, Clermont-Ferrand, France, 4Biochemistry and Molecular Biology Department CHU Clermont-Ferrand, Clermont Université, Université d'Auvergne, EA7281, Clermont-Ferrand, France, 5Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 6Rheumatology Department,, Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, 7Rheumatology, Rheumatology department CHU Clermont-Ferrand, Clermont-ferrand, France, 8Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France

    Background/Purpose: Rheumatoid arthritis (RA) is characterized by increased cardiovascular risk and metabolic changes including cachectic obesity, insulin resistance, dyslipidemia. DMARDs decrease inflammation and could thus…
  • Abstract Number: 461 • 2015 ACR/ARHP Annual Meeting

    Etanercept Has a Better Retention Rate at 10 Years Than Adalimumab in Patients with Rheumatoid Arthritis. Results from Rhumadata®: A Real-Life Clinical Database and Registry

    Denis Choquette1, Louis Bessette2, Jacques Brown3, Boulos Haraoui1, Frédéric Massicotte1, Jean-Pierre Pelletier1, Jean-Pierre Raynauld1, Marie-Anaïs Rémillard4, Diane Sauvageau1, Angèle Turcotte3, Édith Villeneuve1 and Louis Coupal1, 1Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, 2Centre d’Ostéoporose et de Rhumatologie de Québec (CORQ), Québec, QC, Canada, 3Rheumatology, Centre d’ostéoporose et de rhumatologie de Québec (CORQ), Québec, QC, Canada, 4Rhumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada

    Background/Purpose: Very few studies have compare different agents used in the treatment of rheumatoid arthritis (RA) over the very long term. The majority of them…
  • Abstract Number: 462 • 2015 ACR/ARHP Annual Meeting

    Radiographic Progression in Patients with Early Rheumatoid Arthritis Has Not Become Milder over the Past Decades

    Carola Wassenberg1, Rolf Rau2, Siegfried Wassenberg3, Dietmar Krause4 and Christoph Fiehn5, 1Radiology, Friedrich Ebert Krankenhaus, Neumünster, Germany, 2Expert in Rheumatology, Düsseldorf, Germany, 3Rheumaklinik, Themistocles Gluck hospital - Rheumazentrum Ratingen, Ratingen, Germany, 4Dept. for Medical Informatics, Biometry and Epidemiology, Ruhr University, Bochum, Germany, 5ACURA Centre for Rheumatic Diseases, Baden-Baden, Germany

    Background/Purpose: Retrospective studies have promoted the idea that RA has become a milder disease over the past decades[i], [ii]. These findings are questionable because of…
  • Abstract Number: 463 • 2015 ACR/ARHP Annual Meeting

    Treatment with Biologic Agents for RA in Patients with MTX-Associated Lymphoproliferative Disorders

    Takayuki Katsuyama1, Ken-ei Sada1, Noriko Toyota-Tatebe2, Katsue S. Watanabe1, Toru Kiguchi3 and Jun Wada2, 1Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan, 2Department of Medicine and Clinical Science,, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan, 3Department of Internal Medicine, Chugoku Central Hospital, Fukuyama, Japan

    Background/Purpose: Methotrexate (MTX) is known as an anchor drug for the treatment of rheumatoid arthritis (RA), and MTX-associated lymphoproliferative disorders (MTX-LPD) is of current interest.…
  • Abstract Number: 464 • 2015 ACR/ARHP Annual Meeting

    Biologic Therapy Treatment Complications in the Alberta Aboriginal Population with Rheumatoid Arthritis

    Cheryl Barnabe1, Yufei Zheng2, Arto Ohinmaa2, Brenda Hemmelgarn3, Gilaad Kaplan4, Liam Martin5 and Walter Maksymowych6, 1Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2Institute of Health Economics, Edmonton, AB, Canada, 3Division of Nephrology, University of Calgary, Calgary, AB, Canada, 4Division of Gastroenterology, University of Calgary, Calgary, AB, Canada, 5Medicine, University of Calgary, Calgary, AB, Canada, 6Medicine, Medicine, University of Alberta, Edmonton, AB, Canada

    Biologic Therapy Treatment Complications in the Alberta Aboriginal Population with Rheumatoid Arthritis Background/Purpose: Aboriginal people with rheumatoid arthritis (RA) have more severe disease and an…
  • Abstract Number: 465 • 2015 ACR/ARHP Annual Meeting

    MRI Bone Erosion at Baseline Predicts the Subsequent Radiographic Progression in Early-Stage RA Patients Who Achieved in Sustained Clinical Good Response: Sub-Analysis from Nagasaki University Early Arthritis Cohort

    Mami Tamai1, Yoshikazu Nakashima1, Kazuhiko Arima2, Junko Kita1, Masataka Umeda1, Shoichi Fukui1, Ayako Nishino1, Takahisa Suzuki1, Yoshiro Horai1, Akitomo Okada3, Tomohiro Koga1, Shin-ya Kawashiri1,2, Naoki Iwamoto1, Kunihiro Ichinose1, Satoshi Yamasaki4, Hideki Nakamura1, Tomoki Origuchi5, Kiyoshi Aoyagi2, Masataka Uetani6, Katsumi Eguchi7 and Atsushi Kawakami1, 1Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, 2Department of Public Health, Nagasaki University, Nagasaki, Japan, 3Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan, 4Hiroshima University, Hiroshima, Japan, 5Department of Rehabilitation Sciences, Nagasaki University, Nagasaki, Japan, 6Department of Radiology and Radiation Research, Nagasaki University, Nagasaki, Japan, 7Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan

    Background/Purpose: Given the improved detection of joint injury by MRI than by clinical examination, EULAR recommendations for the use of imaging of the joints in…
  • Abstract Number: 466 • 2015 ACR/ARHP Annual Meeting

    Clinical Factors, Anti-Citrullinated Peptide Antibodies and MRI-Detected Subclinical Inflammation in Relation to Progression from Clinically Suspect Arthralgia to Arthritis

    H.W. van Steenbergen1, L. Mangnus2, M. Reijnierse3, T. W. J. Huizinga1 and A.H.M. van der Helm- van Mil2, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Patients with Clinically Suspect Arthralgia (CSA) have, according to their rheumatologists, an increased risk on rheumatoid arthritis (RA), but their actual outcome is unexplored.…
  • Abstract Number: 467 • 2015 ACR/ARHP Annual Meeting

    Clinical Outcomes of Patients with Active Rheumatoid Arthritis with Normal Acute-Phase Reactant Values

    In Je Kim1, Hyesook Park2, Sang-Cheol Bae3 and Jisoo Lee4, 1Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, South Korea, 2Dep of Preventive medicine, Ewha Womans University School of medicine, Seoul, South Korea, 3Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 4Internal Medicine, Ewha Womans Univeristy School of Medicine, Seoul, South Korea

    Background/Purpose: Despite high clinical disease activity measured by joint counts and global assessments, some patients with active rheumatoid arthritis (RA) have normal acute-phase reactant (APR)…
  • Abstract Number: 468 • 2015 ACR/ARHP Annual Meeting

    Clinical and Ultrasonographic Inflammation in DMARD-Naïve Early Rheumatoid Arthritis (RA) – Impact of the 2010 ACR/EULAR Classification Criteria Versus the 1987 ACR Classification Criteria

    Maria K. Jonsson1,2,3, Siri Lillegraven2, Lena B. Nordberg2, Anna-Birgitte Aga2, Hilde B. Hammer4, Inge C Olsen2, Bjørg-Tilde Fevang1,5, Tore K. Kvien2, Espen A. Haavardsholm2 and the ARCTIC Study Group, 1Dept. of Rheumatology, Haukeland University Hospital, Bergen, Norway, 2Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Dept. of Clinical Science, University of Bergen, Bergen, Norway, 4Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Department of Clinical Science, University of Bergen, Bergen, Norway

    Background/Purpose: ACR and EULAR published new classification criteria for RA in 2010, aiming for early identification of patients at risk of developing persistent and erosive…
  • Abstract Number: 469 • 2015 ACR/ARHP Annual Meeting

    Window of Opportunity to Achieve Major Outcomes in Early Rheumatoid Arthritis Patients: How Persistence with Therapy Matters

    Virginia Pascual-Ramos1 and Irazú Contreras-Yáñez2, 1Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: The window of opportunity concept states that there are superior clinical responses and the potential for remission, when patients with rheumatoid arthritis (RA) are…
  • Abstract Number: 470 • 2015 ACR/ARHP Annual Meeting

    Disease Outcome in Patients Fulfilling the 2010 Classification Criteria for Rheumatoid Arthritis: The Impact of the Different Criteria Components

    Ellen Sauar Norli1,2, Gina Hetland Brinkmann2,3, Tore K. Kvien2, Olav Bjørneboe1, Anne Julsrud Haugen3, Halvor Nygaard4, Cathrine Thunem5, Elisabeth Lie2 and Maria Dahl Mjaavatten2, 1Dept. of Rheumatology, Martina Hansens Hospital, Sandvika, Norway, 2Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Dept. of Rheumatology, Østfold Hospital Trust, Fredrikstad, Norway, 4Dept. of Rheumatology, Lillehammer Hospital of Rheumatic Diseases, Lillehammer, Norway, 5Dept. of Rheumatology, Betanien Hospital, Skien, Norway

    Background/Purpose: The 2010 ACR/EULAR classification criteria for rheumatoid arthritis (2010 RA criteria) facilitate early classification of rheumatoid arthritis (RA). The criteria yield a score ranging…
  • Abstract Number: 471 • 2015 ACR/ARHP Annual Meeting

    Impact of Baseline Anti-Cyclic Citrullinated Peptide 2 Antibody Titer on Efficacy Outcomes Following Treatment with Subcutaneous Abatacept or Adalimumab

    Jeremy Sokolove1, M Schiff2, Roy Fleischmann3, Michael Weinblatt4, SE Connolly5, A Johnsen5, J Zhu5, MA Maldonado5, S Patel5 and WH Robinson6, 1Stanford University School of Medicine, Palo Alto, CA, 2University of Colorado, Denver, CO, 3University of Texas Southwestern Medical Center, Dallas, TX, 4Brigham and Women's Hospital, Boston, MA, 5Bristol-Myers Squibb, Princeton, NJ, 6Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA

    Background/Purpose: In patients (pts) with RA, the predictive value of baseline (BL) titers of anti-citrullinated protein antibodies (ACPA), a known biomarker for RA and disease…
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