Abstracts Archive - Page 1689 of 2425 - ACR Meeting Abstracts

Abstract Number: 3257 • 2015 ACR/ARHP Annual Meeting
The Link Between DAS28 and the Short-Term Risk of Acute Coronary Syndrome in RA, and Its Driving Factors
Lotta Ljung^1,2, Thomas Frisell³ and Johan Askling^3,4, ¹Department of Medicine, Solna, Clinical epidemiology unit, Karolinska Institutet, Stockholm, Sweden, ²Department for Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, ³Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden
Background/Purpose: The extent to which a short-term effect of the disease activity adds to the over-risk of coronary events in patients with Rheumatoid Arthritis (RA)…
Abstract Number: 3258 • 2015 ACR/ARHP Annual Meeting
Different Perception of Disease Activity in Multimorbid Rheumatoid Arthritis Patients
Helga Radner^1,2, Kazuki Yoshida^1,3, Sara K. Tedeschi⁴, M Frits⁵, C Iannaccone⁶, N Shadick⁷, Michael Weinblatt¹, Daniel Aletaha⁸, Josef S. Smolen⁹ and Daniel H. Solomon¹⁰, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Department of Epidemiology, Harvard School of Public Health, Boston, MA, ⁴Rheumatology, Brigham & Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁶Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, ⁷Division of Rheumatology, Immunology & Allergy, Brigham and Women's Hosp, Boston, MA, ⁸Rheumatology, Medical University Vienna, Vienna, Austria, ⁹Dept of Medicine 3, Division of Rheumatology, Medical Univ Vienna, Vienna, Austria, ¹⁰Rheumatology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: The patient rating of global rheumatoid arthritis (RA) disease activity (PtGA) is a key variable in composite measures of disease activity as well as…
Abstract Number: 3259 • 2015 ACR/ARHP Annual Meeting
Immunoablation Followed By Autologous Stem Cell Transplantation in Systemic Sclerosis Patients Decreases Significantly the Interferon Signatrue
Shervin Assassi¹, Maureen D Mayes¹, Claudia Pedroza², Jeffrey T. Chang², Daniel E. Furst³, Leslie J. Crofford⁴, Richard Nash⁵, Peter McSweeney⁵, Mary Ellen Csuka⁶, Ellen Goldmuntz⁷, Lynette Keyes-Elstein⁸, Paul Wallace⁹ and Keith Sullivan¹⁰, ¹Rheumatology, University of Texas Medical School at Houston, Houston, TX, ²University of Texas Medical School at Houston, Houston, TX, ³Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁴Medicine, Vanderbilt University, Nashville, TN, ⁵Colorado Blood Cancer Institute, Denver, CO, ⁶Rheum/Med Coll of Wisconsin, Med Coll of Wisconsin, Milwaukee, WI, ⁷NIAID, National Institutes of Health, Bethesda, MD, ⁸Rho Federal Systems, Inc., Chapel Hill, NC, ⁹Roswell Park, Buffalo, NY, ¹⁰Duke University, Durham, NC
Background/Purpose: Previous clinical trials have suggested that immunoablation followed by autologous hematopoietic cell transplantation (HCT) can lead to clinical improvements in systemic sclerosis (SSc). However,…
Abstract Number: 3260 • 2015 ACR/ARHP Annual Meeting
Increased Frequency of Malignancies Synchronous to the Onset of Systemic Sclerosis in Anti-RNA Polymerase III Antibodies Positive Patients: A Eustar Multicentre Study
Maria Grazia Lazzaroni¹, Enrico Colombo², Ilaria Cavazzana¹, Oliver Distler³, Rucsandra Dobrota³, Jasmin Eisenring³, Roger Hesselstrand⁴, Lazlo Czirjak⁵, Cecilia Varju⁵, Gabriella Nagy⁵, Vanessa Smith⁶, Paola Caramaschi⁷, Valeria Riccieri⁸, Eric Hachulla⁹, Katarzyna Romanowska-Próchnicka¹⁰, Alexandra Balbir-Gurman¹¹, Emmanuel Chatelus¹², Ana Carolina Araújo¹³, Yannick Allanore¹⁴, Paolo Airò¹⁵ and EUSTAR , ¹Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, ²Rheumatology and Clinical Immunology Unit, University and Spedali Civili of Brescia, Brescia, Italy, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, ⁵University of Pécs Medical Center, Pécs, Hungary, ⁶Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁷Rheumatology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy, ⁸Department of Internal Medicine and Medical Specialities, University Sapienza, Rome, Italy, ⁹Department of Internal Medicine, University Lille Nord-de-France, Lille, France, ¹⁰Department of Pathophysiology, Medical University of Warsaw and Department of Connective Tissue Diseases, Institute of Rheumatology, Warsaw, Poland, ¹¹B. Shine Rheumatology Unit, Rambam Health Care Campus, Rappaport Faculty of Medicine, Technion - Institute of Technology, Haifa, Israel, ¹²Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, ¹³Serviço de Medicina 2, Hospital de Curry Cabral, Centro Hospitalar Lisboa Central, Lisbon, Portugal, ¹⁴Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France, ¹⁵Rheumatology and Clinical Immunology Unit, Spedali Civili of Brescia, Brescia, Italy
Increased Frequency of Malignancies Synchronous to the Onset of Systemic Sclerosis in Anti-RNA Polymerase III Antibodies Positive Patients: a EUSTAR Multicentre Study Background/Purpose: Several clinical issues…
Abstract Number: 3261 • 2015 ACR/ARHP Annual Meeting
Examining the Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients with Breast Cancer
Dhaval Shah¹, Ram Hirpara¹, Laura K. Hummers¹, Fredrick M. Wigley², Virginia D. Steen³, Robyn T. Domsic⁴ and Ami A. Shah⁵, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD, ³Rheumatology, Georgetown University Medical Center, Washington, DC, ⁴Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁵Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Radiation oncologists are hesitant to treat scleroderma (SSc) patients with cancer due to concerns about triggering exaggerated fibrosis. In this study, we examined SSc…
Abstract Number: 3262 • 2015 ACR/ARHP Annual Meeting
The Influence of Immunosuppressive Therapy on Microangiopathy in Systemic Sclerosis As Measured with Nailfoldcapillaroscopy
Jessica Meijs¹, B. de Boer¹, Anne Schouffoer^1,2, T. W. J. Huizinga³, Hein Putter⁴ and Jeska K. de Vries-Bouwstra¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Haga Hospital, The Hague, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Medical Statitics and Bioinformatics, professor in medical statistics, Leiden, Netherlands
Background/Purpose: Microangiopathy in systemic sclerosis (SSc), as visualized by nailfold videocapillaroscopy (NVC) is a dynamic and sequential process1. In time, NVC patterns progress from early,…
Abstract Number: 3263 • 2015 ACR/ARHP Annual Meeting
The Promis-29 in Systemic Sclerosis: Associations with Clinical Characteristics in the Scleroderma Patient-Centered Intervention Network (SPIN) Cohort
Linda Kwakkenbos^1,2, Brett D. Thombs¹, Susan J. Bartlett^3,4, Marie-Eve Carrier², Marie Hudson¹, Luc Mouthon⁵, Vanessa L. Malcarne⁶, Maureen Sauvé⁷, Dinesh Khanna⁸ and SPIN investigators, ¹McGill University, Montreal, QC, Canada, ²Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada, ³Medicine , Divisions of Clinical Epidemiology, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ⁴Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD, ⁵Paris Descartes University, UPRES-EA 4058, Department of Internal Medicine, Cochin Hospital, Paris, France, ⁶SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, ⁷Scleroderma Societies of Canada and Ontario, Hamilton, QC, Canada, ⁸Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Systemic sclerosis (SSc) has far-reaching physical consequences and impacts health-related quality of life. The Patient-Reported Outcomes Measurement Information System (PROMIS)-29 measure includes four items…
Abstract Number: 3264 • 2015 ACR/ARHP Annual Meeting
Multiplex Serum Protein Analysis in Systemic Sclerosis Defines Potential Anti-Fibrotic Mechanisms and Markers of Response to Hyperimmune Caprine Serum
Niamh Quillinan¹, Kristina E.N. Clark¹, Deirdre McIntosh², Jeffrey Vernes² and Christopher P. Denton³, ¹Rheumatology, UCL Division of Medicine, London, United Kingdom, ²Daval International, London, United Kingdom, ³Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom
Background/Purpose: Hyperimmune caprine serum (HICS) administered by subcutaneous injection over 26 weeks has shown benefit for modified Rodnan skin score in diffuse systemic sclerosis…
Abstract Number: 3265 • 2015 ACR/ARHP Annual Meeting
Sustaining Employment with Arthritis: Can Existing Workplace Policies and Accommodations Make a Difference?
Monique A.M. Gignac^1,2, Elizabeth M. Badley³, Dorcas Beaton⁴, Vicki Kristman⁵, Cameron Mustard⁶, Peter Smith⁶ and Selahadin Ibrahim⁶, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ³Toronto Western Research Institute, Toronto, ON, Canada, ⁴St. Michael's Hospital, Toronto, ON, Canada, ⁵Lakehead University, Toronto, ON, Canada, ⁶Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: Despite improved treatment, many individuals with inflammatory arthritis (IA) and osteoarthritis (OA) report difficulties working, reduced productivity and elevated absenteeism. Lacking is research on…
Abstract Number: 3266 • 2015 ACR/ARHP Annual Meeting
Keeping Baby Boomers in the Labour Force Longer: What Does It Mean for Workers with Arthritis?
Monique A.M. Gignac¹, Elizabeth M. Badley², Dorcas Beaton³, Vicki Kristman⁴, Cameron Mustard⁵, Peter Smith⁵ and Selahadin Ibrahim⁵, ¹Instititue for Work and Health, Toronto, ON, Canada, ²Toronto Western Research Institute, Toronto, ON, Canada, ³St. Michael's Hospital, Toronto, ON, Canada, ⁴Lakehead University, Toronto, ON, Canada, ⁵Institute for Work and Health, Toronto, ON, Canada
Background/Purpose: There is concern that an aging workforce results in lost skills and high burden on pension programs. This has resulted in the dissolution of…
Abstract Number: 3267 • 2015 ACR/ARHP Annual Meeting
Functional Disability in Adolescents Is Predicted By Self-Report of Sleep Problems, Depressive Symptoms, Low Physical Activity and Worst Pain Intensity Levels
Kari Firestone¹, Kim Jones² and Anna Wilson³, ¹School of Nursing, Oregon Health & Science University, Portland, OR, ²Rsch & Develop/Mail Code SN OR, Oregon Health Sciences Univ, Portland, OR, ³OHSU Institute on Development and Disability, Oregon Health & Science University, Portland, OR
Background/Purpose: Pain intensity has been shown to be important in understanding pain related functional disability in adolescents. Additional factors may affect other critical outcomes including…
Abstract Number: 3268 • 2015 ACR/ARHP Annual Meeting
Foot and Ankle Characteristics Associated with Falls in People with Rheumatoid Arthritis: A Prospective Longitudinal Study
Angela Brenton-Rule¹, Nicola Dalbeth², Hylton B. Menz³, Sandra Bassett⁴ and Keith Rome⁵, ¹Podiatry, AUT University, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Musculoskeletal Research Centre, La Trobe University, Bundoora, VIC, Australia, ⁴AUT University, Auckland, New Zealand, ⁵Health & Research Rehabilitation Centre, AUT University, Auckland, AR, New Zealand
Background/Purpose: People with rheumatoid arthritis (RA) have an increased risk of falls. The consequences of falls include loss of confidence and independence, injury and death.…
Abstract Number: 3269 • 2015 ACR/ARHP Annual Meeting
Trends in Prevalence of Knee Pain Among US Adults, National Health Interview Survey, 2002-2010
Jennifer M. Hootman¹, Charles G. Helmick² and Yvonne M. Golightly³, ¹Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ²Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ³Epidemiology, University of North Carolina, Chapel Hill, NC
Trends in prevalence of knee pain among US adults, National Health Interview Survey, 2002-2010 Background/Purpose : Aging of the population as well as the obesity…
Abstract Number: 3270 • 2015 ACR/ARHP Annual Meeting
Correction of Limb Length Inequality in Adults with Knee or Hip Symptoms: A Pilot Study
Yvonne M. Golightly¹, Michael T. Gross², Amanda Nelson³, Leigh F. Callahan⁴ and Joanne M. Jordan⁴, ¹Epidemiology, University of North Carolina, Chapel Hill, NC, ²University of North Carolina, Chapel Hill, NC, ³Division of Rheumatology, Allergy, and Immunology and Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Limb length inequality (LLI; paired lower extremities of unequal length) is associated with knee and hip osteoarthritis (OA) and symptoms consistent with OA (pain,…
Abstract Number: 2 • 2015 ACR/ARHP Annual Meeting
The Neutrophil Protein S100A12 Has Stronger Associations with a Comprehensive Ultrasound Score of Synovitis Than Vascular Endothelial Growth Factor in a Longitudinal Study of Rheumatoid Arthritis Patients
Hilde Haugedal Nordal^1,2 and Hilde Berner Hammer³, ¹Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ²Department of Rheumatology, Haukeland University Hospital, Bergen, Norway, ³Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: S100A12, a neutrophil protein, has proinflammatory effects on immune cells and can activate endothelial cells. The mechanism of action suggests vascular endothelial growth factor…

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