Abstracts Archive - Page 1517 of 2607 - ACR Meeting Abstracts

Abstract Number: 1946 • 2017 ACR/ARHP Annual Meeting
Development of a Multi-Component 3D Arthritic Joint Model
Alexandra Damerau^1,2, Lisa Ehlers^1,2, Moritz Pfeiffenberger^1,2, Igor Ponomarev³, Frank Buttgereit^2,4, Timo Gaber^4,5 and Annemarie Lang^1,2, ¹Rheumatologie und klinische Immunologie, Charité-Universitätsmedizin Berlin, Berlin, Germany, ²Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, ³Research Center of Medical Technology and Biotechnology, Bad Langensalza, Germany, ⁴Rheumatologie und klinische Immunologie, Charité Universitätsmedizin Berlin, Berlin, Germany, ⁵German Rheumatism Research Center (DRFZ) Berlin, Berlin, Germany
Background/Purpose: Our goal is to develop an in vitro 3D joint model to simulate the immune mediated pathogenesis of arthritides in order to present an…
Abstract Number: 1947 • 2017 ACR/ARHP Annual Meeting
Thy1 Is a Positive Regulator of Osteoblast Differentiation and Modulates Bone Homeostasis in Obese Mice
Ananta Paine¹, Collynn Woeller², Nelson Huertas¹, Maria de la Luz Garcia-Hernandez³, Richard Phipps² and Christopher T. Ritchlin⁴, ¹Department of Medicine, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ²Department of Environmental Medicine, School of Medicine and Dentistry,, Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ³Department of Medicine,, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ⁴Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, Division of Allergy, Immunology and Rheumatology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY
Background/Purpose: Thy1 (CD90) is a glycosylated, glycophosphatidylinositol (GPI)-anchored membrane protein originally identified as a marker for mouse T cells but subsequent reports noted expression on…
Abstract Number: 1948 • 2017 ACR/ARHP Annual Meeting
TNF-α Overrides the Ability of RANK Ligand to Induce Osteoclast Differentiation of Classical Circulating Precursors
Cecilia Ansalone¹, Flavia Sunzini¹, Caitlin Duncan¹, Sabarinadh Chilaka¹, Iain B. McInnes² and Carl S. Goodyear³, ¹Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²University of Glasgow, Glasgow, United Kingdom, ³Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: TNF-α is well known to be involved in inflammatory-induced bone destruction. This is widely supported by clinical studies showing reduced bone pathology after anti-TNF-α…
Abstract Number: 1949 • 2017 ACR/ARHP Annual Meeting
Anti-Inflammatory Effects of Standardized Platelet-Rich Plasma Releasates in Knee and Hip OA Chondrocytes
Lucia Gato-Calvo¹, Ángela Vela-Anero², Elena F. Burguera¹ and Francisco J Blanco³, ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade de A Coruña (UDC), A Coruña, Spain, ²Cell Therapy and Regenerative Medicine Group, Department of Medicine, University of A Coruña, A Coruña, Spain, ³Proteomics Group, Rheumatology Division, ProteoRed, PRB2-ISCIII. INIBIC-Hospital Universitario A Coruña,15006 A Coruña-Spain, A Coruña, Spain
Background/Purpose : There is a need to standardize platelet-rich plasma (PRP)-derived products and their dosage to evaluate efficacy for each intended indication. Our purpose here…
Abstract Number: 1950 • 2017 ACR/ARHP Annual Meeting
Cross-Sectional Analysis of Foot Osteoarthritis Frequency and Associated Factors: The Johnston County Osteoarthritis Project
Portia Flowers¹, Amanda Nelson², Howard J. Hillstrom³, Jordan B. Renner⁴, Joanne M. Jordan⁵ and Yvonne M. Golightly⁶, ¹Thurston Arthritis Research Center, University of North Carolina - Chapel Hill, Chapel Hill, NC, ²Division of Rheumatology, Allergy, and Immunology and Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Rehabilitation, Hospital Special Surgery (HSS), New York, NY, ⁴UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁵Thurston Arthritis Research Center, University of North CArolina at Chapel Hill, Chapel Hill, NC, ⁶Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: The rising number of adults with arthritis and associated activity limitations present a serious public health problem. Although studies have explored lower limb…
Abstract Number: 1951 • 2017 ACR/ARHP Annual Meeting
Effect of Initiating Metformin Vs. Sulfonylureas on the Risk of Total Knee Arthroplasty
Yuqing Zhang¹, Christine Peloquin², Na Lu³, Tuhina Neogi³ and David T. Felson³, ¹School Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Metformin is the most widely used first-line therapy for type 2 diabetes. Studies have suggested that metformin reduces inflammation and lowers levels of PGE2,…
Abstract Number: 1952 • 2017 ACR/ARHP Annual Meeting
Trend of Arthrocentesis Utilization Among Inpatients over 10 Years – Data from National Inpatient Sample
Dilli Poudel¹, Rashmi Dhital², Sijan Basnet², Sushil Ghimire², Pragya Shrestha³, Prakash Paudel⁴, Raju Khanal² and Paras Karmacharya⁵, ¹Internal Medicine, Reading Health System, WEST READING, PA, ²Internal Medicine, Reading Health System, West Reading, PA, ³Internal medicine, Reading Health System, West Reading, PA, ⁴Internal Medicine, Berkshire Medical Center, Pittsfield, MA, ⁵Rheumatology, C1-R-041, Leiden University Medical Center (LUMC), Rochester, MN
Background/Purpose: Arthrocentesis (AC) is a common and simple yet invasive procedure with potential of serious complications. There are no studies evaluating how often this procedure…
Abstract Number: 1953 • 2017 ACR/ARHP Annual Meeting
Dietary Quality and Risk of SLE in the Nurses’ Health Studies
Medha Barbhaiya¹, Bing Lu¹, Sara K. Tedeschi², Susan Malspeis³, Jeffrey A. Sparks⁴, Walter C. Willett^5,6, Elizabeth Karlson⁷ and Karen H. Costenbader⁷, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy,, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁵Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Department of Nutrition, Harvard School of Public Health, Boston, MA, ⁷Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Prior studies suggest that high intake of antioxidants, fish, olive oil, and nuts may decrease risk of chronic inflammatory diseases and reduce inflammatory biomarkers.…
Abstract Number: 1954 • 2017 ACR/ARHP Annual Meeting
Association of CRP with BMI in Males and Females
Taik Kim¹, Stephen J. Ganocy², Maria Antonelli³, Douglas Einstadter⁴ and Stanley Ballou¹, ¹Rheumatology, Case Western Reserve University/MetroHealth Medical Center, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH, ³Department of Medicine/Division of Rheumatology, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH, ⁴Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH
Background/Purpose: C-reactive Protein (CRP) is an inflammatory marker commonly used to help aid in diagnosis, assess disease activity or monitor response to therapy. It is…
Abstract Number: 1955 • 2017 ACR/ARHP Annual Meeting
Health Care Provider Advice for Weight Loss Among US Adults with Arthritis, National Health Interview Survey, 2014
Jennifer M. Hootman¹, Miriam G. Cisternas², Louise Murphy³ and Teresa J. Brady⁴, ¹Centers for Disease Control and Prevention, Kennesaw, GA, ²MGC Data Services, Carlsbad, CA, ³Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ⁴Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Most clinical practice guidelines for the management of osteoarthritis recommend weight loss for adults with arthritis who are overweight or obese. A health care…
Abstract Number: 1956 • 2017 ACR/ARHP Annual Meeting
An Approach to Linkage of Registry Data to Medicare Claims Using Multiple Non-Unique Identifiers
Fenglong Xie¹, Lang Chen¹, Huifeng Yun², Jeffrey D Greenberg³ and Jeffrey R. Curtis⁴, ¹Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³NYU School of Medicine, New York, NY, ⁴Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Registries and claims data can complement each other to facilitate observational studies. However, methods to link on multiple non-unique identifiers (MNUI) are limited and…
Abstract Number: 1957 • 2017 ACR/ARHP Annual Meeting
Impact of Maternal Systemic Autoimmune Rheumatic Diseases on Neonatal Outcomes: A Population-Level Analysis
Stephanie Keeling¹, Anamaria Savu² and Padmaja Kaul³, ¹Department of Medicine, University of Alberta, Division of Rheumatology, Edmonton, AB, Canada, ²Canadian Vigour Center, Edmonton, AB, Canada, ³Cardiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The impact of systemic autoimmune rheumatic diseases (SARDS) on peripartum outcomes is not well described at a population level despite the potential for active…
Abstract Number: 1958 • 2017 ACR/ARHP Annual Meeting
Burden of Rheumatic Disease Among Korean Women in Childbearing Years Based on the National Health Insurance Service-National Sample Cohort
Min Kyung Chung¹, Jisoo Lee¹, Eun-Hee Ha² and Ji-Young Shin², ¹Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea, Republic of (South), ²Department of Occupational and Environmental Medicine, Ewha Womans University School of Medicine, Seoul, Korea, Republic of (South)
Background/Purpose: Many rheumatic diseases predominantly affect women in their reproductive years, and have a significant impact on childbearing, but its burden remains incompletely understood. The…
Abstract Number: 1959 • 2017 ACR/ARHP Annual Meeting
Multimorbidity in Patients with Sarcoidosis: A Population-Based Cohort Study
Patompong Ungprasert¹, Eric L. Matteson² and Cynthia S. Crowson³, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Department of Medicine, Division of Rheumatology,Mayo Clinic, Rochester, MN
Multimorbidity in Patients with Sarcoidosis: A Population-Based Cohort StudyBackground/Purpose: Recent studies have suggested an increased risk of comorbidity in patients with sarcoidosis. However, whether…
Abstract Number: 1960 • 2017 ACR/ARHP Annual Meeting
National Survey of Childhood-Onset Rheumatic Diseases Followed up in the Clinical Pediatric Facilities in Japan
Masaaki Mori¹, Syuji Takei², Yasuhiko Itoh³, Ichiro Kobayashi⁴, Minako Tomiita⁵, Nami Okamoto⁶ and Kazuko Yamazaki⁷, ¹Department of Lifetime Clinical Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, ²Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan, ³Department of Pediatrics, Nippon Medical School, Tokyo, Japan, ⁴Department of Allergy and Rheumatology, Chiba Children’s Hospital, Sapporo, Japan, ⁵Department of Allergy and Rheumatology, Chiba Children's Hospital, Chiba, Japan, ⁶Pediatrics, Graduate School of Medicine, Osaka Medical College, Takatsuki, Japan, ⁷Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan
Background/Purpose: We did not grasp how many and where pediatric rheumatic patients exist in Japan quite exactly until now. About juvenile idiopathic arthritis (JIA), child-onset…

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