Abstracts Archive - Page 1407 of 2607 - ACR Meeting Abstracts

Abstract Number: 296 • 2017 ACR/ARHP Annual Meeting
A Module of Genes Describing Low Density Granulocytes Can be Identified and Followed in the Periphery of Lupus Patients
Brian Keggereis¹, Michelle Catalina², Nick Geraci¹, Sarah Heuer², Prathyusha Bachali², Sushma Madamanchi², Peter E. Lipsky² and Amrie Grammer², ¹AMPELBioSolutions and RILITE Research Institute, Charlottesville, VA, ²AMPEL BioSolutions and RILITE Research Institute, Charlottesville, VA
Background/Purpose: Lupus is an autoimmune disease characterized by a type I interferon signature thought to be initiated by granulocyte NETosis. The granulocyte population in the…
Abstract Number: 297 • 2017 ACR/ARHP Annual Meeting
Multiplexed Characterization of Circulating and Joint-Derived Human Neutrophils in Inflammatory Arthritis
Ricardo Grieshaber Bouyer¹, Olha Halyabar², Anais Levescot¹, Kacie Hoyt², Lauren Henderson² and Peter Nigrovic^1,2, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Neutrophils are innate immune cells that play a central role in the initiation of inflammatory arthritis as well as mediating tissue damage. We sought…
Abstract Number: 298 • 2017 ACR/ARHP Annual Meeting
Anabasum (JBT-101) Enhances Resolution of Inflammation in Humans
Madhur Motwani¹, Fran Bennett¹, Mark Tepper², Barbara White², Paul Norris³, Raymond MacAllister¹, Charles Serhan³ and Derek Gilroy¹, ¹University College London, London, United Kingdom, ²Corbus Pharmaceuticals, Norwood, MA, ³Harvard Medical School, Cambridge, MA
Background/Purpose: Certain rheumatic diseases including systemic sclerosis (SSc) are characterized by chronic activation of innate immune responses, leading to excessive fibrosis. A normal innate…
Abstract Number: 299 • 2017 ACR/ARHP Annual Meeting
Bik Plays an Important Role of Cell Proliferation Caused By Nitric Oxide in Rheumatoid Arthritis Synovium
Takeshi Ueha¹, Yoshitada Sakai¹, Kohjin Suzuki², Koji Fukuda³, Toshihisa Maeda³, Hanako Nishimoto³, Shinya Hayashi⁴, Yasushi Miura⁴, Ryosuke Kuroda³ and Akira Hashiramoto², ¹Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, Japan, ²Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan, ³Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan, ⁴Orthpaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
Background/Purpose: Nitric oxide (NO), a proinflammatory mediator responsible for various physiological processes, plays a central role in the pathogenesis of rheumatoid arthritis (RA). As a…
Abstract Number: 300 • 2017 ACR/ARHP Annual Meeting
The DNA-Binding Protein ARID3a Is Associated with Interferon Alpha Production in Lupus Patient Plasmacytoid Dendritic Cells and Neutrophils
Michelle Ratliff¹, Joshua Garton^1,2, Indra Adrianto³, Ambra Pastori⁴, Courtney Montgomery⁵, Patrick Gaffney⁴, Judith A. James^3,6 and Carol Webb^1,7,8, ¹Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Chemistry, University of Oklahoma, Oklahoma City, OK, ³Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁷Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁸Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: We previously demonstrated over-expression of the DNA-binding protein ARID3a in peripheral blood B lymphocytes from patients with systemic lupus erythematosus (SLE) compared to healthy…
Abstract Number: 301 • 2017 ACR/ARHP Annual Meeting
MiR-221-3p Overexpression Impairs Anti-Inflammatory Activity of TLR4-Stimulated M2-Macrophages
Lilian Quero^1,2, Andre Tiaden^1,2 and Diego Kyburz^2,3, ¹Department of Biomedicine, Experimental Rheumatology, University of Basel, Basel, Switzerland, ²Rheumatology, University Hospital Basel, Basel, Switzerland, ³Department of Biomedicine, Experimental Rheumatology, University of Basel, 4051 Basel, Switzerland
Background/Purpose: MicroRNAs (miRNAs) have been shown to contribute to the inflammatory response in rheumatoid arthritis (RA) and several of these miRNAs have been found to…
Abstract Number: 302 • 2017 ACR/ARHP Annual Meeting
From Monocytes to Macrophages: the Pathogeneses of Spontaneous Inflammatory Arthritis in CD11c-Flip-KO (HUPO) Mice
Qi Quan Huang¹, Renee E. Doyle², Philip J. Homan¹, Harris Perlman³, Deborah R. WInter³ and Richard M. Pope², ¹Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: We have generated a CD11c-Flip-KO mouse line (HUPO) that spontaneously develops erosive arthritis with incidence 70-80% at age ≥ 20 weeks. This study aimed…
Abstract Number: 303 • 2017 ACR/ARHP Annual Meeting
Outcomes after Hip Fracture in the Elderly: Does Social Isolation Matter?
Lisa A. Mandl¹, Omar Halawa², Jackie Szymonifka³, Kirsten Grueter⁴ and Joseph Lane⁵, ¹Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, ⁵Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY
Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
Abstract Number: 304 • 2017 ACR/ARHP Annual Meeting
Usefulness of Consecutive Doppler Ultrasound Examinations for Detecting Deep Venous Thrombosis during the Perioperative Period in Patients with Osteoporotic Fractures of the Proximal Femur
Ken Nakaseko and Norihiro Mayumi, Department of Orthopaedic Surgery and Rheumatology, Kuwana City Medical Center, Kuwana Mie, Japan
Background/Purpose: Deep venous thrombosis (DVT) can lead to a venous thromboembolism and increase the risk of a pulmonary thromboembolism (PE). PE is one of the…
Abstract Number: 305 • 2017 ACR/ARHP Annual Meeting
Ultrasonographic Evaluation of the Femoral Cartilage, Achilles Tendon and Plantar Fascia in Young Women Wearing High-Heeled Shoes
Ayşen Akinci¹, Kamal Mezian², Ayşe Merve Ata¹, Murat Kara¹, Şule Şahin Onat³, Eda Gürçay⁴, Aslı Çalışkan¹, Maria Ines Taboas Simoes⁵ and Levent Özçakar¹, ¹Hacettepe University Medical School Department of Physical Medicine and Rehabilitation, Ankara, Turkey, ²Czech Technical University in Prague, Faculty of Biomedical Engineering, Department of Health Care Disciplines and Population Protection, Kladno, Czech Republic, ³Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey, ⁴Gaziler Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey, ⁵PMR hospitalar assistant in Centro Hospitalar Entre Douro e Vouga, E.P.E, Portugal
Background/Purpose: Wearing high-heeled shoes (HHS) may include structural and functional abnormalities due to repetitive stress particularly in the knee and forefoot. The aim of this…
Abstract Number: 306 • 2017 ACR/ARHP Annual Meeting
Relationship between Inflammatory Anterior or Posterior Arch MRI Abnormalities and Clinical Data in Low Back Pain Patients
Helene Braun¹, Clement Geniez¹, Yannick Degboe², Arnaud Constantin³, Alain Cantagrel⁴, Delphine Nigon⁵, Marie Faruch-Bilfeld¹ and Adeline Ruyssen-Witrand⁴, ¹Purpan Hospital, Toulouse, France, ²Department of Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, Toulouse, France, ³Purpan Hospital, toulouse, France, ⁴Rheumatology, Purpan Hospital, Toulouse III University, Toulouse, France, ⁵CHU Purpan, Toulouse, France
Background/Purpose: To compare demographic characteristics, characteristics of pain and functional status according to the presence of inflammatory anterior or posterior arch MRI abnormalities in low…
Abstract Number: 307 • 2017 ACR/ARHP Annual Meeting
Biochemical Intervertebral Disc Alterations in Patients with Low Back Pain and Radiculopathy
Philipp Sewerin¹, Christoph Schleich², Ruben Sengewein³, Matthias Schneider⁴ and Benedikt Ostendorf¹, ¹Department and Hiller-Research-Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ²Dep. for diagnostic and interventional Radiology, Heinrich-Heine University, Duesseldorf, Germany, ³Department and Hiller Research Unit for Rheumatology, Heinrich-Heine University, Düsseldorf, Germany, ⁴Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany
Background/Purpose: To assess the glycosaminoglycan (GAG) content of lumbar intervertebral discs (IVD) in patients with low back pain (LBP) and radiculopathy using glycosaminoglycan chemical exchange…
Abstract Number: 308 • 2017 ACR/ARHP Annual Meeting
Frequency, Morbidity and Healthcare Utilization of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Patients at a University Hospital
Maanas Tripathi¹, Divya Rajmohan², Cody Quirk³, Brooke Beckett³, Donseok Choi⁴, Neha Rich-Garg⁵ and Atul A. Deodhar⁴, ¹University of Miami, FL, Miami, FL, ²Oregon Health & Sciences University, Portland, OR, ³Radiology, Oregon Health & Science University, Portland, OR, ⁴Oregon Health & Science University, Portland, OR, ⁵Northwest Rheumatology Assoc., Portland, OR
Background/Purpose: DISH is a non-inflammatory condition affecting the spine, and characterized by ossification of paravertebral ligaments. DISH is traditionally considered asymptomatic, detected incidentally on spine…
Abstract Number: 309 • 2017 ACR/ARHP Annual Meeting
Compression Assisted Arthrocentesis and Intraarticular Injection
James Bennett¹, Tej Bhavsar¹, Romy Cabacungan², Sabeen Yaqub¹, Monthida Fangtham³, N. Suzanne Emil¹, Roderick Fields⁴, Konstantin Konstantinov⁵, Arthur Bankhurst⁶, William Hayward⁷ and Wilmer Sibbitt Jr.³, ¹Internal Medicine, Division of Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, NM, ²Internal Medicine, Division of Rheumatology, University of New Mexico, Albuquerque, NM, ³Rheumatology, University of New Mexico, Albuquerque, NM, ⁴Internal Medicine/ Rheumatology, University of New Mexico School of Medicine, Albuquerque, NM, ⁵1 University Of New Mexico, University of New Mexico, Albuquerque, NM, ⁶Rheumatology, University of NM Medical Center, Albuquerque, NM, ⁷Exercise and Sport Sciences, New Mexico Highlands University, Las Vegas, NM
Background/Purpose: We hypothesized that compression assisted arthrocentesis of the knee would improve arthrocentesis fluid yields and intraarticular injection outcomes.Methods: We performed conventional arthrocentesis on 215…
Abstract Number: 310 • 2017 ACR/ARHP Annual Meeting
Comparison of Flexed and Extended Knee Arthrocentesis and the Role of Constant Compression
Sabeen Yaqub¹, Tej Bhavsar¹, Romy Cabacungan², James Bennett¹, Monthida Fangtham³, N. Suzanne Emil¹, Roderick Fields⁴, Konstantin Konstantinov⁵, Arthur Bankhurst⁶, Luke Haseler⁷ and Wilmer Sibbitt Jr.³, ¹Internal Medicine, Division of Rheumatology, University of New Mexico Health Sciences Center, Albuquerque, NM, ²Internal Medicine, Division of Rheumatology, University of New Mexico, Albuquerque, NM, ³Rheumatology, University of New Mexico, Albuquerque, NM, ⁴Internal Medicine/ Rheumatology, University of New Mexico School of Medicine, Albuquerque, NM, ⁵1 University Of New Mexico, University of New Mexico, Albuquerque, NM, ⁶Rheumatology, University of NM Medical Center, Albuquerque, NM, ⁷Department of Physiotherapy and Exercise Physiology, Curtin University, Perth, Australia
Background/Purpose: The objective of this study was to determine whether extended versus flexed knee position is superior for arthrocentesis. Methods: 55 clinically effusive knees with…

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