Abstracts Archive - Page 1380 of 2425 - ACR Meeting Abstracts

Abstract Number: 2617 • 2017 ACR/ARHP Annual Meeting
Electrocardiogram Abnormalities Related to Antimalarials in Systemic Lupus Erythematosus
Taneisha McGhie¹, Paula Harvey², Jiandong Su¹, Nicole Anderson³, George A. Tomlinson⁴ and Zahi Touma⁵, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Cardiology, Women's College Hospital, University of Toronto, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Medicine, Mount Sinai Hospital, Toronto, ON, Canada, ⁵Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada
Background/Purpose: Anti-malarials (AM), such as hydroxychloroquine (HCQ) and chloroquine (CQ), have long been used for the treatment of systemic lupus erythematosus (SLE). However, despite their…
Abstract Number: 2618 • 2017 ACR/ARHP Annual Meeting
Why Aren’t All Patients with SLE Taking Hydroxychloroquine? A Retrospective Chart Review
Caroline H. Siegel¹, Jennifer M. Grossman¹, John Fitzgerald¹, Bevra H. Hahn^1,2, Lori Sahakian¹, Eloise Olmos² and Maureen A. McMahon¹, ¹UCLA David Geffen School of Medicine, Los Angeles, CA, ²Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Although previous SLE treatment guidelines recommended judicious use of antimalarials, there is a growing body of evidence demonstrating that HCQ prevents flares, protects against…
Abstract Number: 2619 • 2017 ACR/ARHP Annual Meeting
Hemophagocytic Syndrome in Patients from SLE Registry from the Spanish Society of Rheumatology (RELESSER)
Ana Lois-Iglesias¹, Francisco J. de Toro², Antonio Zea³, María Galindo⁴, Esther Uriarte⁵, Iñigo Rúa-Figueroa⁶ and JM Pego-Reigosa⁷, ¹Rheumatology, University Hospital A Coruña, A Coruña, Spain, ²Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, ³Hospital Ramón y Cajal. Madrid, Madrid, Spain, ⁴Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, ⁵Reumatología, Hospital de Donosti, Donosti, Spain, ⁶Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain, ⁷Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain
Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune systemic rheumatic disease that, in our area, presents hematologic manifestations in approximately 70% of cases1. Some of…
Abstract Number: 2620 • 2017 ACR/ARHP Annual Meeting
The Value of Repeat Biopsy in the Management of Lupus Nephritis Flares
Javier Narváez^1,2, Milagros Ricse², Montserrat Goma³, Francesca Mitjavila⁴, Xavier Fulladosa⁵, Olga Capdevila⁴, Joan Torras⁵, Xavier Juanola^2,6, Ramon Pujol⁴ and Joan Miquel Nolla², ¹Rheumatology Department, Hospital de Bellvitge. Barcelona. Spain, L’Hospitalet de Llobregat, Spain, ²Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Pathology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Internal Medicine, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁵Nephrology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁶Rheumatology, University Hospital Bellvitge, Barcelona, Spain
Background/Purpose: Whether a repeat renal biopsy is helpful during lupus nephritis (LN) flares remains debatable. Our objective was to analyze the clinical utility of repeat…
Abstract Number: 2621 • 2017 ACR/ARHP Annual Meeting
Minimal Renal Affection in Patients with Systemic LUPUS Erythematosus: Characteristics and Evolution
TC Salman-Monte¹, Eva Rodriguez², José Luis Arevalos³, María José Soler³, Clara Barrios³, Jordi Carbonell⁴ and Julio Pascual³, ¹Rheumatology, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain, ²Nephrology, Hospital del Mar/ Parc de Salut Mar, Barcelona, Spain, ³Nephrology, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain, ⁴Rheumatology Unit, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain
Background/Purpose: Lupus nephritis (LN) is the most common organ involvement in Systemic Lupus Erythematosus (SLE). Indications of renal biopsy (RB) are deterioration of renal function…
Abstract Number: 2622 • 2017 ACR/ARHP Annual Meeting
The Benefit of Vitamin D on SLE Disease Activity Is Largely Explained By Renal Activity
Michelle Petri¹, Daniel Goldman² and Laurence S Magder³, ¹Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD, ²Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Epidemiology and Public health, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Low vitamin D is commonly found in SLE. In previous studies, supplementation of vitamin D resulted in improvement in the Physician Global Assessment and…
Abstract Number: 2623 • 2017 ACR/ARHP Annual Meeting
Association between Smoking Status and the Clinical and Serological Characteristics at the Onset of Systemic Lupus Erythematosus. an Inception Cohort Analysis
Jorge Sanchez-Guerrero¹, Afra Al Dhaheri², Stacey Morrison³, Jiandong Su⁴, Dafna D Gladman⁵ and Murray Urowitz⁶, ¹Division of Rheumatology, Toronto Western Hospital, Toronto, AB, Canada, ²Tawam Hospital, Al Ain, United Arab Emirates, ³Rheumatology, Krembil Research Institute, Toronto, ON, Canada, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Department of Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Cigarette smoking regulates both innate and adaptive immunity and is associated with numerous diseases. In some inflammatory diseases smoking is associated with deleterious effects…
Abstract Number: 2624 • 2017 ACR/ARHP Annual Meeting
A Renal Biopsy Should Not Delay Treatment Initiation in Suspected Lupus Nephritis
Astrid Baumann¹, Angela Pakozdi², Andrea Cove-Smith², Debasish Pyne², Michael Sheaff¹ and Ravindra Rajakariar², ¹Barts Lupus Centre, London, United Kingdom, ²Barts Lupus Centre, Barts Health NHS Trust, London, United Kingdom
Background/Purpose: Renal biopsies are considered the gold standard in diagnosing lupus nephritis (LN). ALMS (1), the largest randomized trial in LN, reported the non-inferiority of…
Abstract Number: 2625 • 2017 ACR/ARHP Annual Meeting
Predicting Flares in Patients with Stable Systemic Lupus Erythematosus
Jiacai Cho¹, Manjari Lahiri¹, Lay Kheng Teoh¹, Preeti Dhanasekaran^2,3, Pak Moon Peter Cheung¹ and Aisha Lateef¹, ¹Medicine, Division of Rheumatology, National University Hospital of Singapore, Singapore, Singapore, ²National University of Singapore, singapore, Singapore, ³National University Hospital of Singapore, Singapore, Singapore
Background/Purpose: The course of systemic lupus erythematosus (SLE) varies with periods of quiescence punctuated by flares. Predicting exacerbations allows clinicians to select patients who need…
Abstract Number: 2626 • 2017 ACR/ARHP Annual Meeting
Proton Pump Inhibitor Induced Subacute Cutaneous Lupus Erythematosus: Clinical Characteristics and Outcomes
Yih Jia Poh¹, Shirish Sangle¹, Eleanor Higgins¹, Emma Benton¹, David McGibbon¹ and David D'Cruz², ¹Louise Coote Lupus Unit, Guy's and St Thomas' Hospital, London, United Kingdom, ²Louise Coote Lupus Unit, Guy's and St. Thomas' Hospital, London, United Kingdom
Background/Purpose: Drug induced subacute cutaneous lupus erythematosus has rarely been described. There is a growing literature reporting the association between proton pump inhibitor use and…
Abstract Number: 2627 • 2017 ACR/ARHP Annual Meeting
Characterization of Emergency Department Visits in an Urban Underserved Lupus Cohort
Justin Levinson¹, Maushmi Savjani¹, Diane Zisa² and Ellen M. Ginzler³, ¹Internal Medicine, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ²Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY, ³Rheumatology, Division of Rheumatology, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY
Background/Purpose: SLE patients frequently utilize the Emergency Department (ED), impacting the cost of care and quality of life. We performed a retrospective analysis of ED…
Abstract Number: 2628 • 2017 ACR/ARHP Annual Meeting
Raynaud’s Symptoms and Pregnancy Induced Hypertension in Patients with Systemic Lupus Erythematosus
Sakiko Isojima, Mayu Saito, Yoko Miura and Nobuyuki Yajima, Showa university, Tokyo, Japan
Background/Purpose: Several reports suggested that the incidence of obstetric complications such as pregnancy induced hypertension (PIH) and preterm birth was higher in a pregnant woman…
Abstract Number: 2629 • 2017 ACR/ARHP Annual Meeting
Systemic Lupus Erythematosus Patients Not Complaining Raynaud’s Phenomenon Display Lower Skin Blood Perfusion Than Healthy Subjects
Barbara Ruaro¹, Alberto Sulli¹, Sabrina Paolino², Carmen Pizzorni³, Veronica Tomatis¹, Massimo Patanè¹ and Maurizio Cutolo¹, ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genoa, Italy, ²University of Genova, IRCCS San Martino, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genova, Italy, ³Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova, Italy, Genova, Italy
Background/Purpose: A clinical feature of patients with primary Raynaud's phenomenon (PRP) is the presence of low skin blood perfusion (BP) at the level of hands…
Abstract Number: 2630 • 2017 ACR/ARHP Annual Meeting
Utility of the Korean Version of Systemic Lupus Activity Questionnaire, in Clinical Practice: Its Correlation with Disease Activity Indices of Systemic Lupus Erythematosus
Eun Young Ahn¹, Wonho Lee², Jin Young Moon², Jin Kyun Park², Eun Young Lee³, Eun Bong Lee², Sang-Cheol Bae⁴ and Kichul Shin⁵, ¹Division of Rheumatology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea., Seoul, Korea, Republic of (South), ⁴Department of Rhematology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), ⁵Division of Rheumatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, Korea, Republic of (South)
Background/Purpose: Assessing patient-reported outcomes validated to be associated with disease activity has helped clinicians better understand treatment response of patients with systemic rheumatic disease. Such…
Abstract Number: 2631 • 2017 ACR/ARHP Annual Meeting
Validation of Clinically Relevant Improvement in Children and Adolescents with cSLE
Pinar Ozge Avar Aydin¹, Michael J. Holland², Simone Appenzeller³, Stacy P. Ardoin⁴, Tadej Avcin⁵, Michael W. Beresford⁶, Brian M. Feldman⁷, Francisco Flores⁸, Marisa S. Klein-Gitelman⁹, Beatrice Goilav¹⁰, Raju Khubchandani¹¹, Deborah M. Levy¹², Angelo Ravelli¹³, Nicolino Ruperto¹⁴, Clovis A Silva¹⁵, Scott E. Wenderfer¹⁶, Jun Ying¹⁷ and Hermine I. Brunner¹, ¹Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil, ⁴Pediatric & Adult Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, ⁶On Behalf of the UK JSLE Study Group, Liverpool, United Kingdom, ⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁹Division of Pediatric Rheumatology/PDD PTD, Lurie Children's Hospital of Chicago/Northwestern University, Chicago, IL, ¹⁰Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, ¹¹Department of Paediatrics, Jaslok Hospital and Research Center, Mumbai, India, ¹²Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹³University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, ¹⁴Istituto Giannina Gaslini, Genoa, Italy, ¹⁵Rheumatology Unit, Instituto da Criança, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, São Paulo, Brazil, ¹⁶Nephrology, Baylor College of Medicine, Texas Children's Hospital, houston, TX, ¹⁷Center for Biostatistical Services, University of Cincinnati College of Medicine, Cincinnati, OH
Background/Purpose: Childhood-onset systemic lupus erythematosus (cSLE) is a multisystem autoimmune disease that is characterized by episodes of flares followed by improvement in response to therapy.…

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