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  • Abstract Number: 2497 • 2017 ACR/ARHP Annual Meeting

    The Role of Individual and Country-Level Socio-Economic Factors in Work Participation in Patients with Spondyloarthritis across 22 Countries Worldwide: Results from the Comospa Study

    Santiago Rodrigues Manica1,2, Alexandre Sepriano3,4, Sofia Ramiro5,6, Fernando Pimentel-Santos1,2, Polina Putrik7, Elena Nikiphorou8,9, Anna Moltó10,11, Maxime Dougados11,12, Désirée van der Heijde13, Robert B.M. Landewé14, Filip van Den Bosch15 and Annelies Boonen7, 1CEDOC, NOVA Medical School, Lisbon, Portugal, 2Rheumatology, Hospital Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal, 3CEDOC, NOVA Medical School, Lisboa, Portugal, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 6R. Câmara Pestana 6, CEDOC, NOVA Medical School, Lisbon, Portugal, 7MUMC+, Maastricht, Maastricht, Netherlands, 8Whittington Hospital, London, United Kingdom, 9Academic Rheumatology Department, King's College London, London, United Kingdom, 10Rheumatology B Department, Paris Descartes University, Cochin Hospital, AP-HP,Paris, Paris, France, 117 INSERM (U1153), Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France, 12Paris, Paris, France, 13Leiden University Medical Center, Leiden, Netherlands, 14Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, 15Rheumatology, Ghent University Hospital, Gent, Belgium

    Background/Purpose: Spondyloarthritis (SpA) carries substantial financial costs, including direct costs (use of medical services and treatments) and indirect costs (loss of work productivity). While disease…
  • Abstract Number: 2498 • 2017 ACR/ARHP Annual Meeting

    Rheumatologists Use Different Cut-Offs for Disease Activity in Real Life – the Experience with Golimumab in Ankylosing Spondylitis- Subanalysis from a Non-Interventional German Study

    Jürgen Braun1, Xenofon Baraliakos2, Uta Kiltz1, Klaus Krüger3, Gerd R. Burmester4, Siegfried Wassenberg5 and Matthias H. Thomas6, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Praxiszentrum St. Bonifatius München, München, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, 5Rheumazentrum Ratingen, Ratingen, Germany, 6Medical Affairs, MSD Sharp & Dohme GmbH, Bünde, Germany

    Background/Purpose: International recommendations for the management of axial spondyloarthritis including ankylosing spondylitis (AS) suggest a BASDAI level of disease activity of ≥4 to indicate treatment…
  • Abstract Number: 2499 • 2017 ACR/ARHP Annual Meeting

    Gender Differences in Axial and Peripheral Spondyloarthritis: Results from the Esperanza Cohort

    Claudia Urrego1, Victoria Navarro-Compán2, Eugenio De Miguel3, Juan Mulero Mendoza4, Teresa Ruiz Jimeno5, Cristina Campos Fernandez6 and Pablo Zurita Prada1, 1Rheumatology, Hospital General de Segovia., Segovia, Spain, 2Rheumatology, Hospital Universitario La Paz, Madrid, Spain, 3Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 4Rheumatology, Hospital Puerta de Hierro. Madrid, Madrid, Spain, 5Rheumatology, Hospital Sierrallana. Torrelavega, Santander, Santander, Spain, 6Rheumatology, Hospital Universitario de Valencia., Valencia, Spain

    Background/Purpose: In patients with spondyloarthritis, published data indicate different manifestations and outcomes between genders. The evidence in this regard in patients with early and peripheral…
  • Abstract Number: 2500 • 2017 ACR/ARHP Annual Meeting

    Are Work Outcomes Improved in Axial Spondyloarthritis (axSpA) Patients with Biologic Therapy? Results from the British Society for Rheumatology Register

    Gary J. Macfarlane, Gareth T. Jones and Joanna Shim, Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom

    Background/Purpose: Patients with axial spondyloarthritis (axSpA) identify the ability to stay at work as a priority. Biologic therapy improves disease activity and quality of life…
  • Abstract Number: 2501 • 2017 ACR/ARHP Annual Meeting

    Potential Differences in Axial Spondyloarthritis Disease Activity Categorization Using Different Minimum Values for High-Sensitivity CRP in Ankylosing Spondylitis Disease Activity Score Calculation and Different Definitions of Disease Flare

    Robert B.M. Landewé1, Joachim Sieper2, Uta Kiltz3, Xin Wang4, Mei Li4 and Jaclyn K. Anderson4, 1University of Amsterdam, Amsterdam, Netherlands, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4AbbVie Inc., North Chicago, IL

    Background/Purpose: It has been recommended that the lower limit of high-sensitivity CRP (hsCRP) be restricted to 2 in the Ankylosing Spondylitis Disease Activity Score (ASDAS)…
  • Abstract Number: 2502 • 2017 ACR/ARHP Annual Meeting

    Defining Clinically Important Worsening Based on ASDAS-CRP for Axial Spondyloarthritis: A Data-Based Consensus By the Assessment in Spondyloarthritis International Society (ASAS)

    Anna Molto1, Laure Gossec2, Robert B.M. Landewé3, Désirée van der Heijde4 and Maxime Dougados5, 1Hôpital Cochin, Department of Rheumatology, Paris Descartes University, Paris, France, 2UPMC University Paris 06, Pitié-Salpétrière Hospital, Paris, France, 3Amsterdam Rheumatology & Immunology Center, Netherlands, Amsterdam, Netherlands, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Department of Rheumatology, Paris Descartes University, Hôpital Cochin, Paris, France

    Background/Purpose: Disease flares are increasingly used as outcomes in axial spondyloarthritis (axSpA) trials or observational studies. The objective of this initiative was to define a…
  • Abstract Number: 2503 • 2017 ACR/ARHP Annual Meeting

    Does Maastricht Ankylosing Spondylitis Enthesitis Scores Differ between Ankylosing Spondylitis, Psoriatic Arthritis and Rheumatoid Arthritis Patients?

    Steffan Robstad Nilssen1, Jintana B: Andersen1, Hanne K. Vestaby1, Glenn Haugeberg2 and Brigitte Michelsen3, 1Dept. of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, 2Martina Hansens Hospital, Bærum, Norway, 3Dept. of Rheumatology, Hospital of Southern Norway Trust, kristiansand, Norway

    Background/Purpose: The Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) is an enthesitis index developed and validated as an outcome measure in ankylosing spondylitis (AS), but is…
  • Abstract Number: 2504 • 2017 ACR/ARHP Annual Meeting

    The Validation of Istanbul  Back Disability Index (IBDI) in Axial Spondyloarthritis Patients

    Tuncay Duruoz, Hatice Sule Baklacioglu, Sevtap Acer Kasman and Didem Erdem, PMR Department, Rheumatology Division, Marmara University School of Medicine, Istanbul, Turkey

    Background/Purpose: The IBDI was developed to assess the disability in patients with mechanical low back pain (1) which contains the 18 daily activities questions. The…
  • Abstract Number: 2505 • 2017 ACR/ARHP Annual Meeting

    Trends in Time to Diagnosis in Spondyloarthritis Patients. Association with 2009 ASAS Classification Criteria and Clinical Presentation at Disease Onset. Data from Comospa Study

    Rodolfo Perez-Alamino1, Hernán Maldonado Ficco2, Christian A. Waimann3, José Antonio Maldonado-Cocco4,5, Anna Moltó6, Maxime Dougados7, Désirée van der Heijde8, Robert B.M. Landewé9 and Filip van Den Bosch10, 1Rheumatology Department, Hospital de Clínicas Pte. Dr. Nicolás Avellaneda, Tucumán, Argentina, 2section of Rheumatology, Clinica Regional del Sud, Córdoba, Argentina, Córdoba, Argentina, 3Hospital Dr. Hector Cura, Olavarria, Argentina, 4Buenos Aires University, Consulting Professor of Rheumatology, Buenos Aires University. Argentina, Buenos Aires, Argentina, 5Fundación Reumatológica Argentina, Buenos Aires, Argentina, 6Hôpital Cochin, AP-HP, Paris, France, 7Paris, Paris, France, 8Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 9Academic Medical Center, Amsterdam and Atrium Medical Center, Heerlen, Netherlands, 10Rheumatology, Ghent University Hospital, Gent, Belgium

    Background/Purpose: Diagnostic delay is one of the greatest challenges in Spondyloarthritis (SpA). Methods: We designed a cross-sectional study, including adult patients fulfilling ASAS SpA criteria…
  • Abstract Number: 2506 • 2017 ACR/ARHP Annual Meeting

    In Ankylosing Spondylitis/Axial Spondyloarthritis Smoking Is Associated with a Dose Related Elevation in CRP, Worse Disease Activity and Worse Quality of Life over One Year

    Simon Stebbings1, Mary Wallace2, Andrew A. Harrison3, Nicola Dalbeth4, Douglas White5, Lisa K. Stamp6, Daniel Ching7 and John Highton8, 1Dunedin Hospital, Department of Rheumatology, Dunedin, New Zealand, 2Surgical Sciences, University of Otago, Dunedin, New Zealand, 3Department of Medicine, University of Otago Wellington, Wellington, New Zealand, 4University of Auckland, Auckland, New Zealand, 5Department of Rheumatology, Waikato Clinical School, Hamilton, New Zealand, 6University of Otago, Christchurch, New Zealand, 7Timaru Medical Specialists Ltd, Timaru, New Zealand, 8Dept of Medicine, Univ of Otago Med Sch, Dunedin, New Zealand

    Background/Purpose: Analysis of data from several cohort studies of patients with ankylosing spondylitis (AS) /axial spondyloarthritis (AxSpA) have confirmed earlier suggestions that current smokers have…
  • Abstract Number: 2507 • 2017 ACR/ARHP Annual Meeting

    Dactylitis and Enthesitis Predict Uveitis in Large Axial Spondyloarthropathy Cohort

    Gillian Fitzgerald1, Phil Gallagher2, Catherine Sullivan3, Killian O Rourke4, Claire Sheehy5, Frances Stafford6, Carmel Silke7, Muhammad Haroon8, Ronan Mullan9, Sandy Fraser10, Grainne Murphy11, Shawn Chavrimootoo12, Oliver FitzGerald13 and Finbar O' Shea14, 1Rheumatology, St James's Hospital, Dublin 8, Ireland, 2St. Vincent's University Hospital, Department of Rheumatology, Dublin, Ireland, 3ASRI, Dublin, Ireland, Cork, Ireland, 4Rheumatology, Midlands Regional Hospital, Tullamore, Co Offaly, Ireland, 5Rheumatology, University Hospital Waterford, Waterford, Ireland, 6Rheumatology, Blackrock Clinic, Co Dublin, Ireland, 7Rheumatology, Sligo University Hospital, Sligo, Ireland, 8Rheumatology, Kerry General Hospital, Co Kerry, Ireland, 9Department of Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 10Department of Rheumatology, University Hospitals Limerick, Ireland, Limerick, Ireland, 11Rheumatology, Cork University Hospital, Cork, Ireland, 12Rheumatology, Our Lady's Hospital, Co Meath, Ireland, 13ASRI, Dublin, Ireland, Dublin, Ireland, 14St Jame, Dublin, Ireland

    Background/Purpose: ASRI (Ankylosing Spondylitis Registry of Ireland) is a national registry, designed to provide descriptive epidemiological data on the axial spondyloarthropathy (axSpA) population of Ireland.…
  • Abstract Number: 2508 • 2017 ACR/ARHP Annual Meeting

    Obese Axial Spondyloarthropathy Patients Have Worse Disease Outcomes

    Gillian Fitzgerald1, Phil Gallagher2, Catherine Sullivan3, Killian O Rourke4, Claire Sheehy5, Frances Stafford6, Carmel Silke7, Muhammad Haroon8, Ronan Mullan9, Sandy Fraser10, Grainne Murphy11, Shawn Chavrimootoo12, Oliver FitzGerald13 and Finbar O' Shea1, 1Rheumatology, St James's Hospital, Dublin 8, Ireland, 2St. Vincent's University Hospital, Department of Rheumatology, Dublin, Ireland, 3Rheumatology, UCHG Ireland, Galway, Ireland, 4Rheumatology, Midlands Regional Hospital, Tullamore, Co Offaly, Ireland, 5Rheumatology, University Hospital Waterford, Waterford, Ireland, 6Rheumatology, Blackrock Clinic, Co Dublin, Ireland, 7Rheumatology, Sligo University Hospital, Sligo, Ireland, 8Rheumatology, Kerry General Hospital, Co Kerry, Ireland, 9Department of Rheumatology, Tallaght Hospital, TCD, Dublin 24, Ireland, 10Department of Rheumatology, University Hospitals Limerick, Ireland, Limerick, Ireland, 11Rheumatology, Cork University Hospital, Cork, Ireland, 12Rheumatology, Our Lady's Hospital, Co Meath, Ireland, 13St. Vincent's University Hospital, Department of Rheumatology. UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland

    Background/Purpose: Obesity is a worldwide public health concern, due to its association with morbidity and mortality. Existing literature looking at obesity in axial spondyloarthropathy (axSpA)…
  • Abstract Number: 2509 • 2017 ACR/ARHP Annual Meeting

    High Prevalence of Sarcopenia in Axial Spondyloarthropathy Cohort

    Gillian Fitzgerald1 and Finbar O' Shea2, 1Rheumatology, St James's Hospital, Dublin 8, Ireland, 2St Jame, Dublin, Ireland

    Background/Purpose: Sarcopenia, or age-related loss of muscle mass, is well documented in the general population and is associated with functional limitation and increased mortality. Literature…
  • Abstract Number: 2510 • 2017 ACR/ARHP Annual Meeting

    Prevalence of and Factors Associated with Sarcopenia in Patients of Ankylosing Spondylitis

    Ran Song1, Sang-Hoon Lee1, Ji-Young Choi2, Yeon-Ah Lee2, Seung-Jae Hong2 and Hyung-In Yang3, 1Rheumatology, Kyung Hee University Hospital at Gang dong, Seoul, Korea, Republic of (South), 2Rheumatology, Kyung Hee University Hospital, Seoul, Korea, Republic of (South), 3Kyung Hee University Hospital at Gang dong, Seoul, Korea, Republic of (South)

    Background/Purpose: Sarcopenia is characterized by progressive and generalized loss of skeletal muscle mass and strength with a risk of adverse outcomes such as physical disability…
  • Abstract Number: 2511 • 2017 ACR/ARHP Annual Meeting

    Irritable Bowel Syndrome and Its Impact on Patient-Reported Outcomes in Axial Spondyloarthritis: Is It an Overlooked Comorbidity?

    Tor Olofsson1, Elisabeth Mogard1, Jan Marsal2, Mats Geijer3, Lars Erik Kristensen4, Elisabet Lindqvist1 and Johan K Wallman5, 1Department of Clinical Sciences Lund, Rheumatology, Lund University, Lund, Sweden, 2Department of Clinical Sciences Lund, Gastroenterology, Lund University, Lund, Sweden, 3Department of Radiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden, 4Department of Rheumatology, Copenhagen University Hospital, Frederiksberg and Bispebjerg, The Parker Institute, Copenhagen, Denmark, 5Department of Clincial Sciences Lund, Rheumatology, Lund University, Lund, Sweden

    Background/Purpose: While inflammatory bowel disease (IBD) is a well-known comorbidity in axial spondyloarthritis (SpA), little is known about functional bowel problems, such as irritable bowel…
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