- Abstract Number: 2652 • 2018 ACR/ARHP Annual Meeting - Engaging the Cholinergic Anti-Inflammatory Pathway By Stimulating the Vagus Nerve Reduces Pain and Fatigue in Patients with SLEBackground/Purpose: Musculoskeletal (MS) pain is a common symptom of patients with Systemic Lupus Erythematosus (SLE) affecting up to 95% of patients and contributing to…
- Abstract Number: 2653 • 2018 ACR/ARHP Annual Meeting - Contraceptive Documentation in Systemic Lupus Erythematosus Patients at a Safety Net HospitalBackground/Purpose: Systemic Lupus Erythematosus (SLE) predominately affects reproductive aged women. Contraceptive counseling is an important quality indicator in SLE patient care. Here we evaluate current…
- Abstract Number: 2654 • 2018 ACR/ARHP Annual Meeting - Exposure to Air Pollution and the Onset and Progression of Systemic Lupus ErythematosusBackground/Purpose: Air pollution may contribute to many autoimmune diseases including systemic lupus erythematosus (SLE), but limited information is available on its role in the onset…
- Abstract Number: 2655 • 2018 ACR/ARHP Annual Meeting - SLE-Key® Ruleout Testing in Support of Patient Triage in the Clinical Rheumatology SettingBackground/Purpose: SLE diagnosis and classification can be challenging. The low incidence of SLE limits primary care physician experience with the disease, but the impact of…
- Abstract Number: 2656 • 2018 ACR/ARHP Annual Meeting - Apremilast As Treatment of Refractory Skin Lupus LesionsBackground/Purpose: Skin lesions of lupus may be refractory to standard therapy. Apremilast is an orally small molecule which inhibits phosphodiesterase-4 (PDE-4) that modulates some inflammatory…
- Abstract Number: 2657 • 2018 ACR/ARHP Annual Meeting - Assessment of Habitual Physical Activity and Performance during Maximal Exercise Test in Systemic Lupus Erythematosus PatientsBackground/Purpose: Patients with systemic lupus erythematosus (SLE) present low physical capacity when compared to healthy controls. In addition to chronotropic incompetence during exercise, slow recovery…
- Abstract Number: 2658 • 2018 ACR/ARHP Annual Meeting - Real World Medication Use in Incident Systemic Lupus Erythematosus and Lupus Nephritis PatientsBackground/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease that causes inflammation in connective tissues and can involve multiple organs systems. Lupus nephritis (LN) is…
- Abstract Number: 2659 • 2018 ACR/ARHP Annual Meeting - Clinical Features, Damage Accrual and Survival in Patients with Familial Systemic Lupus Erythematosus (SLE): Data from a Multiethnic, Multinational Latin American Lupus CohortBackground/Purpose: GLADEL (Grupo Latino Americano De Estudio de Lupus) has previously shown that a 14.1% of its patients have relatives with an autoimmune disease (1).…
- Abstract Number: 2660 • 2018 ACR/ARHP Annual Meeting - Low-Dose Interleukin-2 Treatment of Refractory Lupus NephritisBackground/Purpose: Lupus nephritis (LN) is a common and serious organ manifestation of SLE and is associated with substantial patient morbidity and mortality. The production of…
- Abstract Number: 2661 • 2018 ACR/ARHP Annual Meeting - Metformin Combined with Conventional Therapy Increases Absolute Number of Regulatory T Cells in Patients with Systemic Lupus ErythematosusBackground/Purpose:To observe the clinical efficacy of metformin in the treatment of SLE and regulation of CD4+ Treg and Th17 cells.Methods:Thirty-one patients with SLE, fulfilled the ACR…
- Abstract Number: 2662 • 2018 ACR/ARHP Annual Meeting - Changes in Blood Pressure and Proteinuria at One Year in Two Lupus Nephritis Clinical TrialsBackground/Purpose: Hypertension predicts poor long-term renal outcomes for patients with lupus nephritis (LN) [1, 2]. We sought to characterize relationships between blood pressure and proteinuria…
- Abstract Number: 2663 • 2018 ACR/ARHP Annual Meeting - Comparison of Clinical and Laboratory Profiles in 3575 Systemic Lupus Erythematosus Patients with and without Sjögren’s Syndrome: Data from the Spanish Society for Rheumatology Lupus RegistryBackground/Purpose: The clinical coexistence of Systemic Lupus Erythematosus (SLE) and Sjögren's Syndrome (SS) was recognized in 1959. The prevalence of SS among patients with SLE…
- Abstract Number: 2664 • 2018 ACR/ARHP Annual Meeting - Long-Term Clinical Outcomes in a Cohort of Adults with Childhood-Onset Systemic Lupus ErythematosusBackground/Purpose: Childhood-onset SLE (cSLE) is a severe lifelong multisystem autoimmune disease. Long-term outcome data are limited. Here, we report for the first time on the…
- Abstract Number: 2665 • 2018 ACR/ARHP Annual Meeting - Treatment Trends of Systemic Lupus Erythematosus during Early-Years of the DiseaseBackground/Purpose: Systemic lupus erythematosus (SLE) is treated with glucocorticoids, anti-malarials, immunosuppressive medications, and, more recently, biologics (specifically, belimumab and rituximab). While belimumab had positive results…
- Abstract Number: 2666 • 2018 ACR/ARHP Annual Meeting - Trends in Treatment of Systemic Lupus Erythematosus and Lupus Nephritis: 2006-2016Background/Purpose: Glucocorticoids, anti-malarials and conventional immunosuppressive agents have been the mainstay of therapy for systemic lupus erythematosus (SLE) and lupus nephritis (LN); more recently biologic…
