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  • Abstract Number: 2362 • 2017 ACR/ARHP Annual Meeting

    Novel Biomarkers for the Prediction of Subclinical Coronary Artery Atherosclerosis in Patients with Rheumatoid Arthritis

    Joan Bathon1, Jenny Van Eyk2, Nick Knowlton3, Ivan Ferraz-Amaro4, Jon T. Giles5, C. Michael Stein6, Mary Chester M. Wasko7 and Michael Centola8, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Advanced Clinical BioSystems Research Institute , Cedars-Sinai Medical Center, Los Angeles, CA, 3Department of Arthritis and Clinical Rheumatology, Oklahoma Medical Research Foundation, Oklahoma, OK, 4Rheumatology, Hospital Universitario de Canarias, La Laguna, Tenerife, Spain, 5Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 6Medicine, Vanderbilt University Medical Center, Nashville, TN, 7Lupus Center, Pittsburgh, PA, 8Arthritis and Immunology, Oklahoma Medical Research Foundation, Oklahoma, OK

    Background/Purpose: Cardiovascular (CV) disease risk prediction models, that were originally developed for use in the general population, have been found to have suboptimal performance in…
  • Abstract Number: 2363 • 2017 ACR/ARHP Annual Meeting

    Does Galectin-3 Have Utility As a Biomarker of Subclinical Cardiovascular Disease in RA Patients Independently of RA Disease Activity?

    Amanda Nussdorf1, Isabelle Amigues2 and Joan Bathon3, 1Columbia University Medical Center, New York, NY, 2Division of Rheumatology, Columbia University Medical Center, New York, NY, 3Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose: Galectin-3 is a beta-galactoside-binding lectin and is a marker of cardiovascular disease (CVD) in the general population. However, galectin-3 level is also elevated in…
  • Abstract Number: 2364 • 2017 ACR/ARHP Annual Meeting

    Decrease in Cardiovascular Event Excess Risk in Rheumatoid Arthritis Since 2000: A Meta- Analysis of Controlled Studies

    Elisabeth Filhol1, Charlotte Hua2, Anaiz Nutz3, Françoise Flaisler1, Cédric Lukas4, Jacques Morel5, Bernard Combe5 and Cécile Gaujoux-Viala6, 1Rheumatology, Nîmes University Hospital, Nîmes, France, 2Reumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 3Rheumatology, Nîmes University Hospital and Montpellier University, Nîmes, France, 4Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, 5Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 6Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France

    Background/Purpose: Compared with the general population, patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease or events (CE): stroke, Myocardial Infarction (MI),…
  • Abstract Number: 2365 • 2017 ACR/ARHP Annual Meeting

    Poor Cardiovascular Risk Management in Rheumatoid Arthritis Patients Despite an Explicit Cardiovascular Risk Management Program

    Maaike Heslinga1, Inge van den Oever2, E. Griep3, Hanneke Griep-Wentink3, Yvo M. Smulders4, WF Lems5, Maarten Boers6, Alexandre Voskuyl7, Mike J.L. Peters4, Dirkjan van Schaardenburg2 and Michael Nurmohamed8, 1Amsterdam Rheumatology immunology Center | Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center | Reade, Amsterdam, Netherlands, 3Rheumatology, Antonius Hospital, Sneek, Netherlands, 4Internal Medicine, VU University Medical Center, Amsterdam, Netherlands, 5Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, 6Epidemiology & Biostatistics, VU Univ Medical Center F-wing, Amsterdam, Netherlands, 7Department of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, 8Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands

    Background/Purpose: In 2011, we started a cardiovascular (CV) risk management program for rheumatoid arthritis (RA) patients visiting Reade in the Netherlands. We previously reported the…
  • Abstract Number: 2366 • 2017 ACR/ARHP Annual Meeting

    High Uric Acid As a Risk Factor for Cardiovascular Diseases in Rheumatoid Arthritis Patients

    Adeeba Al-Herz1, Ali Aldei1, Khulood Saleh2, Adel Al-Awadhi3, Waleed Al-Kandari2, Eman Hasan4, Aqeel Ghanem5, Mohammad Hussain4, Ibrahim Nahar5, Fatemah Abutiban6, Ahmad Alenizi6, Yaser Ali5, Hebah Alhajeri5, Sawsan Hayat5, Ahmad Khadrawy2, Ammad Fazal2, Khaled Mokaddem1, Agaz Zaman5, Ghada Mazloum5, Youssef Bartella1, Sally Hamed1, Ramia Alsouk6 and Ahmed Al-Saber7, 1Rheumatology, Al-Amiri Hospital, Kuwait city, Kuwait, 2Rheumatology, Farwania Hospital, Farwania, Kuwait, 3Faculty of Medicine, Kuwait, Kuwait, 4Al-Amiri Hospital, Kuwait city, Kuwait, 5Rheumatology, Mubarak Al-Kabeer Hospital, Hawally, Kuwait, 6Rheumatology, Jahra Hospital, Jahra, Kuwait, 7Department of Mathematics, Kuwait Technical College, Kuwait city, Kuwait

    Background/Purpose: Rheumatoid arthritis (RA) patients have an increased risk of cardiovascular diseases (CVD). It is unclear whether an elevated serum uric acid (UA) further increases…
  • Abstract Number: 2367 • 2017 ACR/ARHP Annual Meeting

    The Effect of Glucocorticoids on Bone Mineral Density in Patients with Rheumatoid Arthritis:  a Systematic Review and Meta-Analysis

    Anne-Birgitte Blavnsfeldt1,2, Malissa Dawn Thomsen3, Simon Tarp4, Bente Langdahl2,5, Ellen-Margrethe Hauge2,6 and Annette de Thurah7,8, 1Rheumatology, Aarhus Universityhospital, Aarhus C, Denmark, 2Department of Clinical Medicine, Aarhus University, Aarhus C, Denmark, 3Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark, 4The Parker Institute, Bispebjerg & Frederiksberg Hospital, Copenhagen, Denmark, 5Endocrinology, Aarhus University Hospital, Aarhus, Denmark, 6Aarhus Universityhospital, Aarhus C, Denmark, 7Department of Rheumatology, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, 8Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

    Background/Purpose: The role of glucocorticoids (GCs) in the treatment of rheumatoid arthritis (RA) is widely debated. GCs stimulate bone resorption and impair bone formation. Inflammatory…
  • Abstract Number: 2368 • 2017 ACR/ARHP Annual Meeting

    Global Circumferential Strain By Assessed a Feature Tracking Cardiac Magnetic Resonance (CMR) Imaging  Was Associated with Myocardial Fibrosis in RA Patients

    Yasuyuki Kobayashi1, Hitomi Kobayashi2, Isamu Yokoe3, Atsuma Nishiwaki4, Akiyuki Kotoku5 and Masami Takei4, 1Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 2Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, 4Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 5Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Individuals with RA have a 1.5-2.0 fold higher risk of developing congestive heart failure (CHF) than the general population. It is important to understand…
  • Abstract Number: 2369 • 2017 ACR/ARHP Annual Meeting

    Relationship of Bone Mineral Density and Inflammatory Burden with Carotid Plaque Formation in Rheumatoid Arthritis: A 5-Year Prospective Study

    Na Ri Kim, Jong Wan Kang, Jung Su Eun, Ji Hun Kim, Jin Young Kang, Gi Bum Bae, Sang Jin Lee, Eon Jeong Nam and Young Mo Kang, Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea, Republic of (South)

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease. The incidence of the cardiovascular (CV) disease is significantly increased in patients with RA…
  • Abstract Number: 2370 • 2017 ACR/ARHP Annual Meeting

    Endothelial Nitric Oxide Synthase Gene Polymorphism As a Risk Factor of Hypertension in Patients with Rheumatoid Arthritis

    Mykola Stanislavchuk1,2, Kateryna Zaichko2 and Ayad Sulaiman2, 1Internal Medicine, VNMU n.a. M. Pirogov, Vinnytsia, Ukraine, 2Rheumatology, Vinnytsia Regional Clinical Hospital, Vinnytsia, Ukraine

    Background/Purpose: Rheumatoid arthritis (RA) and hypertension (HT) are multifactorial polygenic diseases. The incidence of hypertension in patients with RA is higher than in the general…
  • Abstract Number: 2371 • 2017 ACR/ARHP Annual Meeting

    The Efficacy of Tofacitinib in Patients with Rheumatoid Arthritis Stratified By Baseline Body Mass Index

    Ara Dikranian1, Miguel Angel Gonzalez-Gay2, Frank Wellborne3, Jose Maria Alvaro-Gracia4, Liza Takiya5, Lori Stockert5, Douglass Chapman6, Svitlana Tatulych7, Palle Dahl8 and Jeffrey R. Curtis9, 1Cabrillo Center for Rheumatic Disease, San Diego, CA, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Houston Institute for Clinical Research, Houston, TX, 4Hospital Universitario de La Princesa, IIS Princesa, Madrid, Spain, 5Pfizer Inc, Collegeville, PA, 6Pfizer Inc, New York, NY, 7Pfizer Inc, Groton, CT, 8Pfizer Inc, Ballerup, Denmark, 9University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This post-hoc analysis aims to explore the efficacy of tofacitinib…
  • Abstract Number: 2372 • 2017 ACR/ARHP Annual Meeting

    Obesity and the Impact on Treat to Target Goals and Functional Ability in RA. Results from Two Multi-Centre UK Inception Cohorts

    Elena Nikiphorou1, Sam Norton2, Patrick Kiely3 and Adam Young4, 1Academic Rheumatology Department, King's College London, London, United Kingdom, 2Academic Rheumatology, King´s College London, London, United Kingdom, 3St George's Hospital, London, United Kingdom, 4University of Hertfordshire, Hertford, United Kingdom

    Background/Purpose: The links between inflammation, obesity and joint dysfunction are well established.   How these translate into clinical disease activity and functional disability in rheumatoid arthritis…
  • Abstract Number: 2373 • 2017 ACR/ARHP Annual Meeting

    Low or High BMI Negatively Impacts RA Disease Activity in an Asian RA Cohort

    Claire Teo1, KP Leong2, CM Woo3, X Tang3, J WL Tan4, TY Lian4 and ET Koh2, 1Rheumatology, Allergy and Immunology Department, Tan Tock Seng Hospital, Singapore, Singapore, 2Rheumatology/Allerg/Immunology, Tan Tock Seng Hospital, Singapore, Singapore, 3Clinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore, 4Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: The association of body mass index (BMI) with the outcomes of rheumatoid arthritis (RA) has been inconsistent in the literature. It is postulated that…
  • Abstract Number: 2374 • 2017 ACR/ARHP Annual Meeting

    Obesity Impacts ESR and Not Other Measures of Rheumatoid Arthritis Disease Activity

    Ana Maheshwari1, Oumoul Barry1 and MJ Bergman2, 1Internal Medicine, Mercy Catholic Medical Center, Darby, PA, 2Medicine, Drexel University College of Medicine, Philadelphia, PA

    Background/Purpose: Disease activity measurement is a cornerstone to treat to target strategy. The impact of body mass index (BMI) on disease activity in rheumatoid arthritis…
  • Abstract Number: 2375 • 2017 ACR/ARHP Annual Meeting

    Does the Body Mass Index Have Any Influence in the Characteristics of Early Arthritis Patients?

    Pablo Moreno Fresneda1, Lola Martínez-Quintanilla Jiménez1, Ana M. Ortiz Garcia2, Eva Tomero3, Rosario García-Vicuña4 and Isidoro Gonzalez-Alvaro2, 1Rheumatology, Rheumatology Division, Hospital Universitario La Princesa, IIS-IP, Madrid, Spain, 2Rheumatology, Rheumatology Service, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, 3Hospital La Princesa. Madrid., Madrid, Spain, 4Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain

    Background/Purpose: Obesity has been proposed as a risk factor to develop rheumatoid arthritis (RA) and it has been associated with a worse response to several…
  • Abstract Number: 2376 • 2017 ACR/ARHP Annual Meeting

    Weight Histories Expose the Systematic Underestimation of the Risks of Obesity on Mortality in Rheumatoid Arthritis

    Joshua Baker1, Bryant R. England2, Ted R. Mikuls3 and Kaleb Michaud4, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Emerging evidence suggests that long-term weight loss is an important confounder that results in an underestimation of the risks of obesity in chronic illness.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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