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  • Abstract Number: 2107 • 2017 ACR/ARHP Annual Meeting

    Therapeutic Response to Prednisone in Relation to Age in Polymyalgia Rheumatica: A Controlled Study

    Aline Charpentier1, Frank Verhoeven2,3, Maxime Sondag1, Xavier Guillot4, Clément Prati5 and Daniel Wendling6, 1rheumatology, CHU de Besançon, Besancon, France, 2EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche-Comté, Besançon, France, 3Service de Rhumatologie, CHRU J Minjoz, Besançon, France, 4EA 4267 FDE, FHU INCREASE, Université de Bourgogne FrancheComté, Besançon, France, 5Service de Rhumatologie, CHU J Minjoz, Besancon, France, 6Service de Rhumatologie, CHU Jean Minjoz, Besancon, France

    Background/Purpose: Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disorder which usually affect patients over 65 years old. Different poor prognostic factors are involved in prednisone…
  • Abstract Number: 2108 • 2017 ACR/ARHP Annual Meeting

    Colchicine Treatment May be Protective Against Ventricular Arrhythmias in FMF Patients

    Aslı Gozek Ocal1, Lutfi Ocal2 and Mehmet Engin Tezcan3, 1Internal Medicine, University of Medical Sciences Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey, 2Cardiology, University of Medical Sciences Kosuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey, 3Rheumatology, University of Medical Sciences Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, Turkey

    Background/Purpose: Familial Mediterranean fever (FMF) is an autoinflammatory disease. Colchicine is used in FMF patients for preventing attacks and amyloidosis. There were conflicting reports as…
  • Abstract Number: 2109 • 2017 ACR/ARHP Annual Meeting

    Hyperferritinemic Syndrome in a General Hospital

    Ignacio Javier Gandino1, Florencia Pierini2, Jose Maximiliano Martinez P3, Santiago Ruta2, Marina Scolnik2 and Enrique R Soriano4, 1Reumatologia, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina, 3Rheumatology, Internal Medicine Service, Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, 4Argentina, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

    Background/Purpose: Hyperferritinemia is associated with inflammatory conditions, such as rheumatologic diseases. Objectives: To determine which diseases are associated with hyperferritinemia in a tertiary hospital; to…
  • Abstract Number: 2110 • 2017 ACR/ARHP Annual Meeting

    Blood Group ”a“ Was Increased in FMF Patients and Blood Group ”0“ May be Associated with Colchicine Resistance

    Abdulsamet Erden1, Ezgi Deniz Batu2, Berkan Armagan3, Hafize Emine Sonmez4, Alper Sari3, Selcan Demir4, Emre Bilgin5, Esra Fırat5, Levent Kilic1, Yelda Bilginer6, Omer Karadag1, Umut Kalyoncu1 and Sedat Kiraz1, 1Department of Internal Medicine, Divison of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Department of Pediatrics, Divison of Rheumatology, Hacettepe University Faculty of Medicine, ANKARA, Turkey, 3Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 4Department of Pediatrics, Divison of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 5Department of Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey, 6Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, ANKARA, Turkey

    Background/Purpose: Colchicine is the main therapy for familial Mediterranean fever (FMF). However, about 5-10% of FMF patients are colchicine-resistant (1). The reason for colchicine resistance…
  • Abstract Number: 2111 • 2017 ACR/ARHP Annual Meeting

    Anti-N-Methyl-D-Aspartate Receptor Encephalitis – Expanding Our Understanding of the Clinical Needs of Pediatric Patients with This Complex Disorder

    Katherine A. Battisti1, Tobias J. Tsai2, Angela Pickersgill3 and Sheetal S. Vora4, 1Emergency Medicine, Nationwide Children's Hospital, Columbus, OH, 2Physical Medicine and Rehabilitation, Levine Children's Hospital/Carolinas Medical Center, Charlotte, NC, 3Pediatrics, Levine Children's Hospital, Charlotte, NC, 4Pediatric Rheumatology, Levine Children's Hospital, Charlotte, NC

    Background/Purpose: Although recognized only 10 years ago, anti-N-Methyl-D-Aspartate receptor encephalitis (anti-NMDAR encephalitis) has become a leading cause of encephalitis with an identifiable etiology in pediatric…
  • Abstract Number: 2112 • 2017 ACR/ARHP Annual Meeting

    Anti-TNFα Versus Rituximab in Refractory Peripheral Ulcerative Keratitis Associated to Rheumatic Diseases. Multicenter Study of 24 Patients

    Lucia C. Domínguez-Casas1, Vanesa Calvo-Río1, Olga Maiz-Alonso2, Ana Blanco3, Emma Beltran4, Lucía Martínez Acosta5, Maria Concepcion Alvarez de Buergo6, Esteban Rubio-Romero7, David Diaz-Valle8, R López-González9, Angel Garcia-Aparicio10, Antonio Juan Mas11, Enar Pons1, Rosalia Demetrio12, Nuria Vegas-Revenga1, José Luis Martín-Varillas1, Belén Atienza-Mateo1, Carlos Fernández-Díaz1, Jose L. Hernández13, Miguel Angel González-Gay1 and Ricardo Blanco1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 2Hospital Universitario Donostia. San Sebastian. Spain, Donostia, Spain, 3Ophthalmology, Hospital Universitario Donostia. San Sebastian. Spain, San Sebastián, Spain, 4Rheumatology, Hospital General Universitario de Valencia. Spain, Valencia, Spain, 5Ophtalmology, Hospital Peset. Valencia. Spain, Valencia, Spain, 6Rheumatology, Hospital Río Carrión. Palencia. Spain, Palencia, Spain, 7Hospital Universitario Virgen del Rocío. Sevilla. Spain, Sevilla, Spain, 8Hospital Clínico San Carlos. Madrid. Spain, Madrid, Spain, 9Rheumatology, Complejo Hospitalario de Zamora. Spain, Zamora, Spain, 10Rheumatology, Hospital de Toledo. Toledo. Spain, Toledo, Spain, 11Rheumatology, Hospital Son Llàtzer. Palma de Mallorca. Spain, Mallorca, Spain, 12Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 13Internal Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain

    Background/Purpose: Peripheral ulcerative keratitis (PUK) is a severe inflammation of the outer portions of the cornea that may lead to perforation. It may be associated…
  • Abstract Number: 2113 • 2017 ACR/ARHP Annual Meeting

    Familial Mediterranean Fever in Chinese Adult Patients

    Di Wu and Min Shen, Rheumatology, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose :Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease (AUID) worldwide. There have been hardly any cases reported in Chinese population. We…
  • Abstract Number: 2114 • 2017 ACR/ARHP Annual Meeting

    Interstitial Pneumonia with Autoimmune Features (IPAF): Are There Definable Subsets?

    Sepehr Mesdaghinia1, Julio Arturo Huapaya2, Brainerd Ewarien2 and Virginia D. Steen1, 1Rheumatology, MedStar Georgetown University Hospital, Washington, DC, 2Medicine, MedStar Georgetown University Hospital, Washington, DC

    -       Background/Purpose: Interstitial lung disease (ILD) can be an early manifestation of an occult connective tissue disease (CTD).  It is important to separate these patients…
  • Abstract Number: 2115 • 2017 ACR/ARHP Annual Meeting

    Mast Cell Activation Features in Ehlers-Danlos/Joint Hypermobility Patients: A Retrospective Analysis in Light of an Emerging Disease Cluster

    Dave Lee1 and Eric Mueller2, 1Arthritis Northwest, PLLC, Spokane, WA, 2Discus Analytics LLC., Spokane, WA

    Background/Purpose: Mast cells are immune cells often residing in connective tissue, best known for their role in allergic and anaphylactic responses1. Mast cell activation syndrome…
  • Abstract Number: 2116 • 2017 ACR/ARHP Annual Meeting

    Evaluation of Connective Tissue Diseases in Patients Presenting with Interstitial Lung Disease in a Referral Center in Santiago, Chile

    Verónica Wolff1,2, Matías Florenzano1, Angela Rivera3, Carolina Cuellar4, Juan Maya5, Mauricio Salinas1,6, Cristian Ibarra1, Angélica Bello7 and Daniela Soto8, 1Rheumatic Lung diseases Unit, Instituto Nacional del Tórax, Santiago, Chile, 2Rheumatology Unit, Hospital del Salvador, Facultad de Medicina, Universidad de Chile, Santiago, Chile, 3Rheumatology Unit, Hospital Del Salvador, Facultad de Medicina, Universidad de Chile, Santiago, Chile, 4Rheumatology unit, Hospital Del Salvador, Facultad de Medicina, Universidad de Chile, SANTIAGO, Chile, 5Rheumatology Unit, Hospital del Salvador. Facultad de Medicina. Universidad de Chile, Santiago, Chile, 6Facultad de Medicina, Universidad de Chile, Santiago, Chile, 7Instituto Nacional del Tórax - Universidad de Chile, SANTIAGO, Chile, 8Instituto Nacional del Tórax - Universidad de Chile, Santiago, Chile

    Background/Purpose: Connective tissue diseases (CTDs) are systemic autoimmune disorders that can compromise the lung. Interstitial lung disease (ILD) is one of the mayor forms of…
  • Abstract Number: 2117 • 2017 ACR/ARHP Annual Meeting

    C-Reactive Protein and Serum Amyloid a  in Sepsis, Acute Appendicitis and  Familial Mediterranean Fever

    Oguzhan Selvi1, Serdal Ugurlu2, Murat Bolayirli3, Kenan Barut4, Sezgin Sahin4, Amra Adrovic4, Mustafa Akker5, Bilgesu Ergezen6, Osman Simsek7, Ozgur Kasapcopur4,8 and Huri Ozdogan1, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 3Istanbul University, Cerrahpasa Medical Faculty, Department of Biochemistry, Istanbul, Turkey, 4Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, 5Department of Anesthesiolog, Sisli Hamidiye Training and Research Hospital, Istanbul, Turkey, 6Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 7Istanbul University, Cerrahpasa Medical Faculty, Department of General Surgery, Istanbul, Turkey, 8Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy

    Background/Purpose: Familial Mediterranean Fever (FMF) is an autoinflammatory disease characterized by recurrent inflammatory attacks. Attacks are accompanied by substantial increase in acute phase reactants such…
  • Abstract Number: 2118 • 2017 ACR/ARHP Annual Meeting

    Asymptomatic Tendinitis of Flexor Digitorum Tendons in Patients with Type 2 Diabetes : A Single-Center, Cross-Sectional Prevalence Study

    Kyung Min Ko1, Jun-Ki Min2 and Su-Jin Moon3, 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South), 2Bucheon St. Mary's Hospital, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Bucheon, Korea, Republic of (South), 3Bucheon St. Mary's Hospital, Division of rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Bucheon, Korea, Republic of (South)

    Background/Purpose: Diabetes is a metabolic disease that is characterized by chronic and persistent hyperglycemia that eventually results in microvascular and macrovascular complications. These vascular complications…
  • Abstract Number: 2119 • 2017 ACR/ARHP Annual Meeting

    Rheumatological Immune Related Adverse Events in Malignancy Patients Treated with Anti-Programmed Cell Death (PD) 1 Antibodies

    Emma Mitchell1, Peter Lau2, Chloe Khoo2, Kortnye Smith2, Benjamin Brady2, Mark Shackleton2, Grant McArthur2, Ian Wicks1,3,4 and Shahneen Sandhu2, 1Rheumatology, Royal Melbourne Hospital, Melbourne, Australia, 2Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia, 3Medicine, University of Melbourne, Melbourne, Australia, 4Wicks Lab, Walter and Eliza Hall Institute, Melbourne, Australia

    Background/Purpose: Immune checkpoint inhibitors (ICIs), including anti-programmed cell death 1 (anti-PD 1) antibodies, are established therapies for advanced malignancies, including melanoma, and non-small cell lung…
  • Abstract Number: 2120 • 2017 ACR/ARHP Annual Meeting

    Quality, Content and Readability Assessment of Patient Education Websites Relating to Ehlers-Danlos Syndrome

    Ahmed Omar1,2, Laura Passalent3, Leslie Soever4, Medha Soowamber5 and Simon Carette6, 1Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 3Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 4Toronto General Hospital, Toronto, ON, Canada, 5University Health Network, Toronto, ON, Canada, 6Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Ehlers-Danlos Syndrome (EDS) is a heritable connective tissue disease that presents in myriad ways. Education is an essential component in managing this complex condition.…
  • Abstract Number: 2121 • 2017 ACR/ARHP Annual Meeting

    Autoantibodies As Biomarkers for the Identification of Pre-Clinical Stages of Autoimmune Diseases: Demonstration of Inflammatory and Fibrotic Activity in the Liver of Asymptomatic and Biochemically Normal Individuals with Anti-Mitochondria Antibodies

    Danielle Baldo1, Alessandra Dellavance1, Maria Lucia Ferraz2 and Luis Eduardo C. Andrade3,4, 1Research and Development Department, Fleury Medicine and Health Laboratories, São Paulo, Brazil, 2Gastroenterology Division, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, 3Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil, 4Immunology Division, Fleury Medicine and Health, São Paulo, Brazil

    Background/Purpose: Circulating autoantibodies precede clinical onset of several autoimmune diseases. The characteristics of the so-called pre-clinical stage of autoimmune diseases are poorly understood. Anti-mitochondria autoantibodies…
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